Abstract:
AIMS AND OBJECTIVES:To examine the impact and obstacles that individual Institutional Research Ethics Committee (IRECs) had on a large-scale national multi-centre clinical audit called the National Benchmarks and Evidence-based National Clinical guidelines for Heart failure management programmes Study. BACKGROUND:Multi-centre research is commonplace in the health care system. However, IRECs continue to fail to differentiate between research and quality audit projects. METHODS:The National Benchmarks and Evidence-based National Clinical guidelines for Heart failure management programmes study used an investigator-developed questionnaire concerning a clinical audit for heart failure programmes throughout Australia. Ethical guidelines developed by the National governing body of health and medical research in Australia classified the National Benchmarks and Evidence-based National Clinical guidelines for Heart failure management programmes Study as a low risk clinical audit not requiring ethical approval by IREC. RESULTS:Fifteen of 27 IRECs stipulated that the research proposal undergo full ethical review. None of the IRECs acknowledged: national quality assurance guidelines and recommendations nor ethics approval from other IRECs. Twelve of the 15 IRECs used different ethics application forms. Variability in the type of amendments was prolific. Lack of uniformity in ethical review processes resulted in a six- to eight-month delay in commencing the national study. CONCLUSIONS:Development of a national ethics application form with full ethical review by the first IREC and compulsory expedited review by subsequent IRECs would resolve issues raised in this paper. IRECs must change their ethics approval processes to one that enhances facilitation of multi-centre research which is now normative process for health services. RELEVANCE TO CLINICAL PRACTICE:The findings of this study highlight inconsistent ethical requirements between different IRECs. Also highlighted are the obstacles and delays that IRECs create when undertaking multi-centre clinical audits. However, in our clinical practice it is vital that clinical audits are undertaken for evaluation purposes. The findings of this study raise awareness of inconsistent ethical processes and highlight the need for expedient ethical review for clinical audits.
journal_name
J Clin Nursjournal_title
Journal of clinical nursingauthors
Driscoll A,Currey J,Worrall-Carter L,Stewart Sdoi
10.1111/j.1365-2702.2007.02219.xsubject
Has Abstractpub_date
2008-08-01 00:00:00pages
2212-20issue
16eissn
0962-1067issn
1365-2702pii
JCN2219journal_volume
17pub_type
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journal_title:Journal of clinical nursing
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journal_title:Journal of clinical nursing
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