Abstract：
:The aim of this study was to evaluate the associations of environmental exposure to dioxins with diabetes among general inhabitants in Japan. A cross-sectional study was performed on 1374 participants, who were not occupationally exposed to dioxins, aged 15-73 years, living widely in 75 different residential areas of 25 prefectures in Japan through 2002-2006. Seven polychlorinated dibenzo-p-dioxins (PCDDs), 10 polychlorinated dibenzofurans (PCDFs), 12 dioxin-like polychlorinated biphenyls (PCBs), which are assigned a toxic equivalency factor, and biochemical factors were determined in fasting blood. A questionnaire survey on life-style including past history of diseases and treatments was also performed. We examined the associations of the accumulated toxic equivalents (TEQs) of PCDDs+PCDFs, dioxin-like PCBs and total dioxins with prevalent diabetes. Simple and partial correlation analyses revealed that HbA1c correlated with the accumulated TEQs of PCDDs+PCDFs, dioxin-like PCBs and total dioxins. In logistic regression analyses, the third and the highest quartiles of dioxin-like PCBs had adjusted odds ratios (ORs) of 3.07 (95% CI 1.16-8.81) and 6.82 (95% CI 2.59-20.1) compared to the reference (first plus second quartiles). On the other hand, the highest but not the third quartiles of PCDDs+PCDFs and total dioxins had significantly higher adjusted ORs compared to the respective references. These associations persisted when the subjects with poor liver or poor renal function were removed from the analysis. This recent representative data from general inhabitants in Japan showed associations of environmental exposure to dioxins, especially dioxin-like PCBs, with diabetes.
journal_name
Environ Resjournal_title
Environmental researchauthors
Uemura H,Arisawa K,Hiyoshi M,Satoh H,Sumiyoshi Y,Morinaga K,Kodama K,Suzuki T,Nagai M,Suzuki Tdoi
10.1016/j.envres.2008.06.002subject
Has Abstractpub_date
2008-09-01 00:00:00pages
63-8issue
1eissn
0013-9351issn
1096-0953pii
S0013-9351(08)00131-Xjournal_volume
108pub_type
杂志文章abstract：BACKGROUND:We previously reported increased risk of breast cancer associated with early life exposure to two measures of air pollution exposure, total suspended particulates (TSP) and traffic emissions (TE), possible proxies for exposure to polycyclic aromatic hydrocarbons (PAHs). Exposure to PAHs has been shown to be ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.11.040
更新日期：2018-02-01 00:00:00
abstract：:Complex mixture exposures, such as those associated with water sources, are an important issue in health risk assessment. This study assessed the cytotoxicity of chemical mixtures extracted from water sources in regions of the Huai River Basin with high cancer incidences and built statistical models of cytotoxicity ba...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2014.12.027
更新日期：2015-02-01 00:00:00
abstract：OBJECTIVES:Uranium miners are chronically exposed to radon and its progeny, which are known to cause lung cancer and may be associated with leukemia. This study was undertaken to evaluate risk of non-lung solid cancers among uranium miners in Příbram region, Czech Republic. METHODS:A retrospective stratified case-coho...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2011.01.008
更新日期：2011-04-01 00:00:00
abstract：:Calcium has been proposed to diminish metal toxicity by the modulation of the oxidative stress. This study explores the effects of Ca availability and metal exposure on oxidative stress biomarkers in great tit (Parus major) nestlings. Nests were supplemented with Ca (Ca-supplemented group) or not supplemented (Control...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.01.047
更新日期：2019-04-01 00:00:00
abstract：:Multivariate statistical techniques, cluster analysis (CA) and factor analysis/principal component analysis (FA/PCA), were applied to analyze the similarities or dissimilarities among the sampling sites to identify spatial and temporal variations in water quality and sources of contamination (natural and anthropogenic...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2007.10.008
更新日期：2008-02-01 00:00:00
abstract：:Some studies have reported an association between overexposure to selenium and risk of amyotrophic lateral sclerosis (ALS), a rare degenerative disease of motor neurons. From 1986 through 2015, we followed a cohort in Northern Italy that had been inadvertently consuming tap water with unusually high concentrations of ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.108742
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:There is evidence that adult lead exposure increases cancer risk. IARC has classified lead as a 'probable' carcinogen, primarily based on stomach and lung cancer associations. METHODS:We studied mortality among men in a lead surveillance program in 11 states,. categorized by their highest blood lead (BL) te...
journal_title：Environmental research
pub_type： 杂志文章,多中心研究
doi：10.1016/j.envres.2014.03.008
更新日期：2014-07-01 00:00:00
abstract：BACKGROUND:Previous studies have found that human mobility restrictions could not only prevent the spread of COVID-19, but also improve the air quality because of the reduction of industrial production, transportation and traffic. It is noteworthy that air quality is also closely related to the risk of COVID-19 infecti...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109911
更新日期：2020-10-01 00:00:00
abstract：:This study examines the relationship between road traffic noise, self-reported sleep quality and mental health. The study is cross-sectional and based on data from a survey conducted in Oslo, Norway, in 2000. Psychological distress (Hopkins Symptom Checklist, HSCL-25) was measured along with self-reported somatic heal...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2014.02.010
更新日期：2014-05-01 00:00:00
abstract：:Lead levels (Pb) have been linked to both hyper- and hypo-reactivity of hypothalamic-pituitary-adrenal axis (HPA) axis to acute stress in animals and humans. Similarly, allostatic load (AL), the 'wear and tear' of chronic stress, is associated with inadequate HPA axis activity. We examined whether Pb levels would be a...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.01.012
更新日期：2017-04-01 00:00:00
abstract：:The arid region of Northwest China, located in the central Asia, responds sensitively to global climate change. Based on the newest research results, this paper analyzes the impacts of climate change on hydrology and the water cycle in the arid region of Northwest China. The analysis results show that: (1) In the nort...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2014.12.029
更新日期：2015-05-01 00:00:00
abstract：:Ultrafine particles (UFPs) have emerged as a potentially important environmental health concern as they are produced in large numbers by vehicle emissions and may contribute to previously reported associations between traffic pollution and acute cardiovascular morbidity. This review examines recent epidemiological evi...
journal_title：Environmental research
pub_type： 杂志文章,评审
doi：10.1016/j.envres.2012.03.001
更新日期：2012-05-01 00:00:00
abstract：:An exploratory survey was undertaken in the fall 1995 open-water fishing season with nine Bangladeshi and nine Vietnamese-origin sportfishers. Survey methodology and techniques of dietary and fish intake assessment were adapted to the cultural values and second language of each community. A 70-item instrument assessin...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.1998.3929
更新日期：1999-02-01 00:00:00
abstract：OBJECTIVE:This study aims to evaluate the association of air quality index (AQI) with cardiometabolic risk factors in a nationally representative sample of healthy adolescents. METHODS:This nationwide survey was conducted among a stratified multi-stage probability sample of students, aged 10-18 years, from 27 province...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2014.07.010
更新日期：2014-10-01 00:00:00
abstract：:Polycyclic aromatic hydrocarbons (PAHs) and phthalic acid esters (PAEs) which are structurally featured with one or more aromatic skeletons are often regarded as two important groups of organic pollutants due to the widespread distribution and notorious toxic effects in soils. Relative to the great number of structura...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.108838
更新日期：2019-12-01 00:00:00
abstract：:The effects of cadmium on the immune system have been extensively studied, although relatively little is known about the nature of the interaction between cadmium and lymphocytes. We describe studies that examine the uptake and subcellular distribution of cadmium in resting and mitogen-activated mouse splenic lymphocy...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(89)80071-4
更新日期：1989-08-01 00:00:00
abstract：BACKGROUND:The number of studies on air pollution with birth defects as the primary outcome has increased dramatically over the past two decades, but the potential role of specific air pollutants in congenital limb anomalies remains unclear. OBJECTIVES:To evaluate associations between preconception and first-trimester...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109643
更新日期：2020-08-01 00:00:00
abstract：:Air pollution epidemiological studies suggest that elevated exposure to fine particulate matter (PM2.5) is associated with higher prevalence of term low birth weight (TLBW). Previous studies have generally assumed the exposure-response of PM2.5 on TLBW to be the same throughout a large geographical area. Health effect...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2015.06.044
更新日期：2015-10-01 00:00:00
abstract：BACKGROUND:Inorganic arsenic is a lung, bladder, and skin carcinogen. One of the major sources of exposure to arsenic is through naturally contaminated drinking water. While positive associations have been observed between arsenic in drinking water and prostate cancer, few studies have explored this association in the ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2016.04.030
更新日期：2016-07-01 00:00:00
abstract：:In the face of multiple habitat alterations originating from both natural and anthropogenic factors, the fast-changing environments pose significant challenges for maintaining ecosystem integrity. Machine learning is a powerful tool for modeling complex non-linear systems through exploratory data analysis. This study ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109262
更新日期：2020-05-01 00:00:00
abstract：:Dam construction has significantly altered riparian hydrological regime and environmental conditions in the reservoir region, yet knowledge concerning how bacterial community and N-cycling genes respond to these changes remains limited. In this study, we investigated the bacterial community composition, network struct...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2021.110717
更新日期：2021-01-06 00:00:00
abstract：:The objective of this short paper is to call upon the scientific community to channel its attention to the duty and heedfulness of social justice issues. While recognized for decades the impact of social injustice on public health and its disproportionate effects on poorer communities, little has been done to systemat...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110675
更新日期：2020-12-26 00:00:00
abstract：:The extensive use of a geographic information system (GIS) and remote sensing in ecological risk assessment from a spatiotemporal perspective complements ecological environment management. Chromophoric dissolved organic matter (CDOM), which is a complex mixture of organic matter that can be estimated via remote sensin...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.06.020
更新日期：2017-10-01 00:00:00
abstract：:Lead (Pb) isotopic composition analysis is a useful tool to accurately identify the origin of Pb in environmental media. The existing calculation method of the contribution of Pb sources from Pb isotope ratios greatly restricted the development of Pb contamination source apportionment. In the present study, a new dist...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109475
更新日期：2020-06-01 00:00:00
abstract：:Soil pollution from heavy metals poses a serious risk for environment and public health. Phytoremediation is an eco-friendly and cheaper alternative compared to chemical-physical techniques. We carried out in vitro tests where three microorganisms Trichoderma harzianum, Saccharomyces cerevisiae and Wickerhamomyces ano...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109427
更新日期：2020-06-01 00:00:00
abstract：:The present study aimed to evaluate methylmercury in fish and human hair samples from an important hydroelectrical reservoir, Balbina (Brazil, Amazon). It presents a quite intense fishing activity and there is no known goldmining activity in its watershed. Fish and human hair were analyzed with a new extraction techni...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.1998.3836
更新日期：1998-05-01 00:00:00
abstract：:The Mediterranean Basin is undergoing a warming trend with longer and warmer summers, an increase in the frequency and the severity of heat waves, changes in precipitation patterns and a reduction in rainfall amounts. In this unique populated region, which is characterized by significant gaps in the socio-economic lev...
journal_title：Environmental research
pub_type： 杂志文章,评审
doi：10.1016/j.envres.2019.109107
更新日期：2020-03-01 00:00:00
abstract：:Methylmercury (MeHg) is the most bioavailable and toxic form of the globally distributed pollutant Hg. Organisms of higher trophic levels living in aquatic ecosystems have potentially higher concentrations of MeHg. In this work, we analysed both MeHg and inorganic Mercury (Hg(II)) concentrations from dorsal feathers o...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109526
更新日期：2020-07-01 00:00:00
abstract：:The effect of cadmium on thyroxine (T4) outer ring monodeiodination was studied in vivo and in vitro in the rat liver. One microgram of T4 was incubated with rat liver homogenates in 50 mM Tris--HCl buffer, pH 7.4, with or without 0.5, 5, and 50 mM dithiothreitol (DTT) for 60 min in the presence of 10(-8) to 10(-3) M ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(87)80206-2
更新日期：1987-04-01 00:00:00
abstract：:The present study assessed the protective effect of chitosan-nanoencapsulated quercetin (Qu-ChiNPs) against oxidative stress caused by silver nanoparticles (AgNPs). To this end, the transcription of prime genes regulating hepatic Keap1-Nrf2 pathway as well as downstream antioxidant enzymes were monitored prior to and ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109477
更新日期：2020-06-01 00:00:00
