Abstract:
:One fifth of neurons in the medial-temporal lobe of human epilepsy patients respond selectively to categories of images, such as faces or cars. Here we show that responses of hippocampal neurons are rapidly modified as subjects alternate (over 60 sec) between two tasks (1) identifying images from a category, or (2) playing a simple video game superimposed on the same images. Category-selective responses, present when a subject identifies categories, are eliminated when the subject shifts to playing the game for 87% of category-selective hippocampal neurons. By contrast, responses in the amygdala are present during both tasks for 72% of category-selective amygdalar neurons. These results suggest that attention to images is required to evoke selective responses from single neurons in the hippocampus, but is not required by neurons in the amygdala.
journal_name
J Cogn Neuroscijournal_title
Journal of cognitive neuroscienceauthors
Steinmetz PNdoi
10.1162/jocn.2008.21017subject
Has Abstractpub_date
2009-02-01 00:00:00pages
347-58issue
2eissn
0898-929Xissn
1530-8898journal_volume
21pub_type
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