Abstract:
PURPOSE/OBJECTIVES:To apply the Hanahan and Weinberg conceptual framework for tumor development to the specific biomarkers observed or expressed in ovarian cancer. DATA SOURCES:Data-based publications, topical reviews, and book chapters. DATA SYNTHESIS:Articles specific to ovarian cancer were reviewed to examine whether the six rules from the Hanahan and Weinberg conceptual framework were applicable to biomarkers of ovarian cancer. This approach allows for the application of a general framework for the development of solid tumors to the development of ovarian cancer. CONCLUSIONS:The six rules for tumor cell development outlined in the Hanahan and Weinberg conceptual framework are applicable to biomarkers expressed or observed in patients with ovarian cancer. IMPLICATIONS FOR NURSING:Oncology nurses can enhance their clinical teaching by integrating this information into their practice. Nurses who conduct research on ovarian cancer can use this framework to guide the selection of biomarker(s) for these studies. Finally, nurse educators can use this framework when teaching students key concepts in the care of patients with cancer.
journal_name
Oncol Nurs Forumjournal_title
Oncology nursing forumauthors
McLemore MR,Miaskowski C,Aouizerat BE,Chen LM,Dodd Mdoi
10.1188/08.ONF.403-409subject
Has Abstractpub_date
2008-05-01 00:00:00pages
403-9issue
3eissn
0190-535Xissn
1538-0688pii
8PW0TMP588173U7Tjournal_volume
35pub_type
杂志文章,评审abstract:PURPOSE/OBJECTIVES:To assess the PCHIMX-1 (Doran International), a new sterile medical device intended by its manufacturer to improve the quality and safety of cytotoxic drug infusions, as well as its influence on manipulation times required for pharmacy technicians and nurses and its effect on infusion line outflow pa...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/10.ONF.E370-E376
更新日期:2010-11-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To investigate nurses' planning and implementation of individualized patient care in relation to patients' emotional distress as assessed by nurses and whether nurses and patients perceived the implemented care in a similar manner. DESIGN:Prospective, comparative. SETTING:Five oncologic-hematologic...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/10.ONF.E34-E42
更新日期:2010-01-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To evaluate outcomes of an intervention designed to promote sleep and modify fatigue after adjuvant breast cancer chemotherapy. DESIGN:Prospective, repeated measures, quasi-experimental, feasibility study. SETTING:Midwestern urban oncology clinics. SAMPLE:21 female participants, ages 43-66 years (...
journal_title:Oncology nursing forum
pub_type: 临床试验,杂志文章
doi:10.1188/03.ONF.513-522
更新日期:2003-05-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To determine predictors of fall events in hospitalized patients with cancer and develop a scoring system to predict fall events. DESIGN:Retrospective medical record review. SETTING:A 1,200-bed tertiary care hospital in northeastern Ohio. SAMPLE:145 patients with cancer who did not have a fall even...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/12.ONF.E407-E415
更新日期:2012-09-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To review the literature regarding the development of hyperglycemia associated with neoadjuvant agents used in the treatment of solid tumor cancers. DATA SOURCES:Research articles were obtained from PubMed, CINAHL®, and Cochrane Reviews. The following search terms were used alone and in combination:...
journal_title:Oncology nursing forum
pub_type: 杂志文章,评审
doi:10.1188/14.ONF.E343-E354
更新日期:2014-11-01 00:00:00
abstract::Recently, clinicians and researchers alike have challenged the long-standing impression that survivors of bone marrow transplantation (BMT) experience a less than optimal quality of life (QOL). Despite the accumulating evidence suggesting that most adult survivors adjust relatively well within two to five years after ...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:
更新日期:1993-11-01 00:00:00
abstract::At the request of the ONS Board of Directors, a survey was conducted to determine the degree to which oncology nurses performed services listed in the Physicians Current Procedural Terminology manual--services for which physicians are reimbursed. Using a format modeled on a similar study of nurses in general, 100 rand...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract:PURPOSE:To explore perspectives of hospitalized adults with cancer regarding engagement in fall prevention plans. The primary aim was to discover new knowledge about patients' perspectives and improve the design of fall prevention strategies. A secondary aim was to compare fall-related perspectives of patients who had ...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/20.ONF.457-468
更新日期:2020-07-01 00:00:00
abstract::The primary goal of the thousands of registered trials in cancer research is to extend survival. With evaluation of efficacy, safety, and tolerability, healthcare providers must ensure that the principles described in the Belmont Report are upheld and that patients are truly informed when signing a consent form. In th...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/16.ONF.694-696
更新日期:2016-11-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To describe the quality of life (QOL) of long-term cancer survivors. DESIGN:Descriptive, mailed survey. SETTING:Membership of the National Coalition for Cancer Survivorship (NCCS), which is a nonprofit, peer-support network for people living with cancer. SAMPLE:687 (57%) of the 1,200 members of NC...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:
更新日期:1995-07-01 00:00:00
abstract:OBJECTIVES:To examine the association between performance-based neurocognitive and patient-reported cognitive function tests and identify characteristics that may explain observed discrepancies as a means to advance intervention development. SAMPLE & SETTING:40 adults diagnosed with a primary brain tumor (PBT) (hi...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/20.ONF.E1-E12
更新日期:2020-01-01 00:00:00
abstract::This phenomenologic study described the structure of self-transcendence in eight gay men with AIDS. The men provided oral or written descriptions of experiences associated with feelings of increased interconnectedness with others, sense of well-being, and meaning and purpose in life. The data were analyzed using Colai...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:
更新日期:1993-10-01 00:00:00
abstract:PROBLEM IDENTIFICATION:Oral anticancer medication (OAM) use has been steadily increasing, leading to several patient benefits. A notable challenge for nurses is accurate monitoring of patient OAM regimens because nonadherence is associated with poor health outcomes and decreased survival. Currently, no gold standard me...
journal_title:Oncology nursing forum
pub_type: 杂志文章,评审
doi:10.1188/16.ONF.576-582
更新日期:2016-09-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To examine the cultural beliefs and attitudes of African American prostate cancer survivors regarding the use of complementary and alternative medicine (CAM) modalities. RESEARCH APPROACH:Mixed methods with primary emphasis on a phenomenology approach. SETTING:In-person interviews in participants' ...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/07.ONF.359-364
更新日期:2007-03-01 00:00:00
abstract::One goal of oncology nursing is to help patients achieve the best possible quality of life. In the conventional care perspective, quality of life has four aspects: physical, emotional, social, and spiritual. From the complementary care perspective, it is defined as harmony of body, mind, and spirit. Integrating these ...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/02.ONF.25-27
更新日期:2002-01-01 00:00:00
abstract::Quality of life (QOL) was assessed in 10 patients receiving treatment with recombinant methionyl human granulocyte colony-stimulating factor (r-met-GCSF). The Ferrans & Powers Quality of Life Index (Cancer II) was administered at three different time points to patients with severe chronic neutropenia. Mean overall QOL...
journal_title:Oncology nursing forum
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1991-11-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To describe computer experience and preferences for multimedia design. DESIGN:Prospective, descriptive. SETTING:Physician office and outpatient cancer centers in an urban area in the southeastern United States. SAMPLE:Convenience sample of 22 volunteer patients with cancer from four racial groups....
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/06.ONF.787-792
更新日期:2006-07-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To analyze cancer brochures to estimate their reading level and assess their readability. DESIGN:Quantitative. SAMPLE:10 cancer brochures published by various cancer organizations. METHODS:SMOG was used to estimate reading grade level of the brochures; the Readability Assessment Instrument (RAIN) ...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/03.ONF.867-870
更新日期:2003-09-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To describe the quality of life (QOL) experienced by long-term survivors of cervical cancer and the factors that promoted their adaptation. DESIGN:Qualitative. SETTING:Homes and offices in the northeastern United States. SAMPLE:19 women diagnosed with cervical cancer from 1975-1995. METHODS:Semis...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/08.ONF.897-903
更新日期:2008-11-01 00:00:00
abstract:PROBLEM IDENTIFICATION:Involvement in treatment decision making (TDM) is considered a key element of patient- and family-centered care and positively affects outcomes. However, for adolescents and young adults (AYAs) with cancer, little is known about the current state of knowledge about their perspective on and involv...
journal_title:Oncology nursing forum
pub_type: 杂志文章,评审
doi:10.1188/19.ONF.E22-E37
更新日期:2019-01-13 00:00:00
abstract:PURPOSE/OBJECTIVES:To describe the usefulness of daily pain management diaries to outpatients with cancer who participated in a randomized clinical trial of the PRO-SELF Pain Control Program. DESIGN:Randomized clinical trial in which a daily pain management diary was used for data collection in the control group and f...
journal_title:Oncology nursing forum
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1188/02.ONF.1304-1313
更新日期:2002-10-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To investigate the relationships among physiologic variables, fatigue, and quality of life (QOL) in patients with multiple myeloma. DESIGN:Cross-sectional, descriptive, exploratory. SETTING:Outpatient ambulatory care clinics at a tertiary oncology center. SAMPLE:56 patients with multiple myeloma w...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/09.ONF.209-216
更新日期:2009-03-01 00:00:00
abstract:PURPOSES/OBJECTIVES:To describe the importance of a professional code of ethics and values in guiding and supporting the practice of nurses and to present the proposed Oncology Nursing Society (ONS) Statement of Core Values. DATA SOURCES:Published articles and books on nursing ethics and bioethics, as well as authors'...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To review and critique the studies that have investigated chemotherapy-induced impairments in cognitive function in women with breast cancer. DATA SOURCES:Published research articles and textbooks. DATA SYNTHESIS:Although studies of breast cancer survivors have found chemotherapy-induced impairment...
journal_title:Oncology nursing forum
pub_type: 杂志文章,评审
doi:10.1188/05.ONF.329-342
更新日期:2005-03-05 00:00:00
abstract:PROBLEM IDENTIFICATION:Identifying people with hematologic cancer who are at risk of deteriorating and dying is essential to enable open, honest discussions, leading to appropriate decision making and effective end-of-life care. . LITERATURE SEARCH:PubMed, CINAHL®, PsycINFO, and the Cochrane Central Register of Contro...
journal_title:Oncology nursing forum
pub_type: 杂志文章,评审
doi:10.1188/16.ONF.E178-E187
更新日期:2016-09-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To explore perceptions of colorectal cancer (CRC) and self-reported CRC screening behaviors among ethnic subgroups of U. S. blacks. DESIGN:Descriptive, cross-sectional, exploratory, developmental pilot. SETTING:Medically underserved areas in Hillsborough County, FL. SAMPLE:62 men and women aged 50...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/10.ONF.581-591
更新日期:2010-09-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To describe the development and implementation of a comprehensive menopausal assessment (CMA) and intervention program for women with a history of breast cancer. DATA SOURCES:Published articles selected from computerized databases, conference proceedings, bibliographies of pertinent articles and boo...
journal_title:Oncology nursing forum
pub_type: 杂志文章,评审
doi:10.1188/03.ONF.393-407
更新日期:2003-05-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To determine the feasibility of collecting symptom data at home from school-age children with acute lymphoblastic leukemia (ALL) and from their fathers and mothers and to obtain initial descriptions of pain, sleep disturbance, and fatigue experienced by the family members at home. DESIGN:Prospective...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/06.ONF.641-646
更新日期:2006-05-03 00:00:00
abstract:PURPOSE/OBJECTIVES:To compare the effectiveness of two low-intensity approaches for distressed patients with cancer and caregivers who had called cancer helplines seeking support. Baseline distress was hypothesized as a moderator of intervention effect. DESIGN:Randomized trial. SETTING:Community-based cancer helpline...
journal_title:Oncology nursing forum
pub_type: 杂志文章,随机对照试验
doi:10.1188/14.ONF.E256-E266
更新日期:2014-07-01 00:00:00
abstract::Human-caused climate change is a global emergency, and its harms are predicted to increase exponentially in the coming years, particularly if unsustainable practices continue unmitigated. Adverse effects of climate change on communities affected by or at risk for cancer, such as frail older adults, are already measura...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/20.ONF.135-144
更新日期:2020-03-01 00:00:00