Inflammation and genomics in the critical care unit.

Abstract:

:Inflammation is a physiologic response to irritants, injury, and infection. Inflammatory dysregulation is believed to contribute to mortality and morbidity in illnesses common to critical care units, such as burns, trauma, sepsis, and cardiovascular disease. This article reviews the approaches used to investigate the molecular basis of inflammatory function. Genomic findings are providing insight into clinical diagnosis and treatment of inflammatory derangements in critically ill patients.

authors

Winkelman C

doi

10.1016/j.ccell.2008.01.007

subject

Has Abstract

pub_date

2008-06-01 00:00:00

pages

213-21, vi

issue

2

eissn

0899-5885

issn

1558-3481

pii

S0899-5885(08)00008-7

journal_volume

20

pub_type

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