Abstract:
PURPOSE:Our aim was to develop a screening test to predict Dravet syndrome before the first birthday based on the clinical characteristics of infants and the SCN1A mutation analysis.
METHODS:Ninety-six patients who experienced febrile seizures before the age of one were enrolled. The patients were divided into two groups-the Dravet syndrome group (n = 46) and the non-Dravet syndrome group (n = 50). We compared the clinical characteristics before one year of age of the two groups. We analyzed all coding exons of the SCN1A gene by the direct sequencing method. Scores from 0 to 3 were assigned to each risk factor based on the odds ratio and p-value.
RESULTS:An age of onset of febrile seizure
journal_name
Epilepsiajournal_title
Epilepsiaauthors
Hattori J,Ouchida M,Ono J,Miyake S,Maniwa S,Mimaki N,Ohtsuka Y,Ohmori Idoi
10.1111/j.1528-1167.2007.01475.xsubject
Has Abstractpub_date
2008-04-01 00:00:00pages
626-33issue
4eissn
0013-9580issn
1528-1167pii
EPI1475journal_volume
49pub_type
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