Abstract:
:A facile stereoselective synthesis of (Z)- and (E)-allyl sulfides has been accomplished from Morita-Baylis-Hillman acetates in one-pot by treatment with benzene thiol in the presence of catalytic amounts of 15% aqueous NaOH and TBAI in DMSO at room temperature. The method has been applied for the synthesis of (Z)-3-(4-methoxybenzylidene)thiochroman-4-one, a potent antifungal compound.
journal_name
Chem Pharm Bull (Tokyo)journal_title
Chemical & pharmaceutical bulletinauthors
Das B,Chowdhury N,Damodar K,Banerjee Jdoi
10.1248/cpb.55.1274subject
Has Abstractpub_date
2007-08-01 00:00:00pages
1274-6issue
8eissn
0009-2363issn
1347-5223pii
JST.JSTAGE/cpb/55.1274journal_volume
55pub_type
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