Estimating the future health burden of chronic hepatitis C and human immunodeficiency virus infections in the United States.

abstract：:To evaluate, among 70 hepatitis C virus (HCV)-monoinfected and 36 human immunodeficiency virus (HIV)-coinfected naïve patients with genotypes 1/4 receiving weight-adjusted pegylated interferon-alpha-2b/ribavirin, viral kinetics and the feasibility to predict treatment failure measuring early HCV-RNA decreases. HCV-RNA...

journal_title：Journal of viral hepatitis

authors： Moreno A,Bárcena R,García-Garzón S,Moreno L,Quereda C,Muriel A,Zamora J,Mateos ML,Pérez-Elías MJ,Antela A,Diz S,Moreno A,Moreno S

更新日期：2006-07-01 00:00:00

abstract：:To evaluate the cost-effectiveness of ledipasvir/sofosbuvir (LDV/SOF) in treatment-naïve patients with chronic hepatitis C (CHC) genotype 1 (GT1) in the absence or mild fibrosis (F0-F1) versus advanced fibrosis (F2-F4), from the perspective of the Spanish Health System. A Markov model was developed to simulate disease...

journal_title：Journal of viral hepatitis

authors： Buti M,Domínguez-Hernández R,Oyagüez I,Casado MA,Esteban R

更新日期：2017-09-01 00:00:00

abstract：:We evaluated the effect of sustained virologic response (SVR) from direct-acting antiviral (DAA)- and interferon-based treatments on hepatocellular carcinoma (HCC) risk in a large population-based cohort in Canada. We used data from the BC Hepatitis Testers Cohort, which includes ~1.3 million individuals tested for HC...

journal_title：Journal of viral hepatitis

authors： Janjua NZ,Wong S,Darvishian M,Butt ZA,Yu A,Binka M,Alvarez M,Woods R,Yoshida EM,Ramji A,Feld J,Krajden M

更新日期：2020-08-01 00:00:00

abstract：:Drug users with chronic hepatitis C virus (HCV) infection are frequently co-infected with human immunodeficiency virus-1 (HIV-1), but it is still not clear whether HIV-1 worsens the natural history of hepatitis C. To investigate this, we conducted a multicentre observational study in 163 drug addicts with histological...

journal_title：Journal of viral hepatitis

authors： Romeo R,Rumi MG,Donato MF,Cargnel MA,Viganò P,Mondelli M,Cesana B,Colombo M

更新日期：2000-07-01 00:00:00

abstract：:Long-term safety of treatment with hepatitis B virus (HBV) polymerase inhibitors is a concern. Adefovir dipivoxil (ADV) therapy has previously been associated with impairment of renal function. Limited data are available on the safety of combination therapy with nucleos(t)ide analogues and interferon alfa (IFNα). The ...

journal_title：Journal of viral hepatitis

authors： Mederacke I,Yurdaydin C,Großhennig A,Erhardt A,Cakaloglu Y,Yalcin K,Gurel S,Zeuzem S,Zachou K,Chatzikyrkou C,Bozkaya H,Dalekos GN,Manns MP,Wedemeyer H,Hep-Net\/International Delta Hepatitis Study Group.

更新日期：2012-06-01 00:00:00

abstract：:The incidence of, and risk factors for, acute hepatitis A (AHA) were assessed by using data collected from the Italian surveillance system of acute viral hepatitis (SEIEVA). To this end, a case-control study within a population-based surveillance for acute viral hepatitis was performed. AHA incidence has been estimate...

journal_title：Journal of viral hepatitis

authors： Tosti ME,Spada E,Romanò L,Zanetti A,Mele A,SEIEVA collaborating group.

更新日期：2008-10-01 00:00:00

abstract：:Mixed cryoglobulinaemia, when not secondary to other well-defined immunological disorders, is commonly associated with hepatitis C virus (HCV) infection. However, a minority of cases lack evidence of HCV infection and are, therefore, defined as 'true essential' mixed cryoglobulinaemias. We thoroughly investigated thre...

journal_title：Journal of viral hepatitis

authors： Casato M,Lilli D,Donato G,Granata M,Conti V,Del Giudice G,Rivanera D,Scagnolari C,Antonelli G,Fiorilli M

更新日期：2003-11-01 00:00:00

abstract：:Hepatitis delta virus (HDV) RNA editing controls the formation of hepatitis-delta-antigen-S and -L and therefore indirectly regulates HDV replication. Editing is thought to be catalysed by the adenosine deaminase acting on RNA1 (ADAR1) of which two different forms exist, interferon (IFN)-alpha-inducible ADAR1-L and co...

journal_title：Journal of viral hepatitis

authors： Hartwig D,Schütte C,Warnecke J,Dorn I,Hennig H,Kirchner H,Schlenke P

更新日期：2006-03-01 00:00:00

abstract：:This open label study was initiated to assess the safety and efficacy of lymphoblastoid interferon-alpha (IFN-alpha) and thymosin alpha 1 (T alpha 1) in the treatment of 11 patients with chronic hepatitis B, who had failed to respond to standard IFN-alpha 2b therapy, and in four interferon naive patients. These fiftee...

journal_title：Journal of viral hepatitis

authors： Rasi G,Mutchnick MG,Di Virgilio D,Sinibaldi-Vallebona P,Pierimarchi P,Colella F,Favalli C,Garaci E

更新日期：1996-07-01 00:00:00

abstract：:There are few extant studies on the prevalence of HBV infection in couples preparing for pregnancy. We assessed the prevalence of hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) in couples preparing for pregnancy in rural China, and the association between HBV prevalence and the statuses of HBsAg...

journal_title：Journal of viral hepatitis

authors： Liu J,Zhang S,Wang Q,Shen H,Zhang M,Zhang Y,Yan D,Liu M

更新日期：2017-08-01 00:00:00

abstract：:Chronic hepatitis C infection leads to increased hepatocyte apoptosis. Because engulfment of apoptotic bodies (ABs) by hepatic stellate cells (HSC) is profibrogenic, we compared the effects of ABs derived from hepatitis C virus (HCV)-negative vs HCV-infected (Con1+) Huh7 hepatoblastoma cells on fibrogenic and activati...

journal_title：Journal of viral hepatitis

authors： Gieseler RK,Marquitan G,Schlattjan M,Sowa JP,Bechmann LP,Timm J,Roggendorf M,Gerken G,Friedman SL,Canbay A

更新日期：2011-11-01 00:00:00

abstract：:Cameroon is thought to have one of the highest prevalences of hepatitis C virus (HCV) infection in the world (4.9% among adults). A marked cohort effect exists in several communities where ≈50% of the elderly are infected. Better assessment of HCV distribution is needed for planning treatment programmes. We tested for...

journal_title：Journal of viral hepatitis

authors： Njouom R,Siffert I,Texier G,Lachenal G,Tejiokem MC,Pépin J,Fontanet A

更新日期：2018-08-01 00:00:00

abstract：:Hepatitis delta virus (HDV) is a serious cause of liver-related morbidity and mortality. Coexistent infection with HDV tends to aggravate the course of hepatitis B virus (HBV)-associated liver disease. The aim of this study was to determine the prevalence of HDV infection among patients chronically infected with HBV i...

journal_title：Journal of viral hepatitis

authors： Bahcecioglu IH,Aygun C,Gozel N,Poyrazoglu OK,Bulut Y,Yalniz M

更新日期：2011-07-01 00:00:00

abstract：:The efficacy of monotherapy with interferon (IFN) (conventional or pegylated IFN) in dialysis patients with chronic hepatitis C remains unclear, although a number of clinical trials have been published addressing this issue. The aim of the study was to evaluate the efficacy and safety of monotherapy by conventional or...

journal_title：Journal of viral hepatitis

authors： Fabrizi F,Dixit V,Messa P,Martin P

更新日期：2008-02-01 00:00:00

abstract：:The aim of this study was to assess the validity of categorization of chronic hepatitis B viral infection into stages or phases based upon measures of disease activity and viral load, assuming these phenotypes will be useful for prognostication and determining the need for antiviral therapy. We assessed the phenotype ...

journal_title：Journal of viral hepatitis

authors： Di Bisceglie AM,Lombardero M,Teckman J,Roberts L,Janssen HL,Belle SH,Hoofnagle JH,Hepatitis B Research Network (HBRN).

更新日期：2017-04-01 00:00:00

abstract：:Cholangiocarcinoma is the second most common liver cancer in the world. The aetiology of the disease is diverse incorporating a variety of conditions leading to biliary stasis, biliary and liver inflammation, but a large number of cases still occur in the absence of established risk factors. Its incidence and mortalit...

journal_title：Journal of viral hepatitis

authors： Ralphs S,Khan SA

更新日期：2013-05-01 00:00:00

abstract：:Bacteremia has rarely been reported in patients receiving treatment for hepatitis C virus (HCV) infection. We describe the features and investigation of four cases of Staphylococcus aureus bacteremia occurring between 3 November 2004 and 10 January 2005 in patients on therapy for chronic HCV infection. The unusual occ...

journal_title：Journal of viral hepatitis

authors： Webster D,Ahmed R,Tandon P,Chui L,McDonald RR,Obarianyk A,Antonishyn N,Doucette K

更新日期：2007-08-01 00:00:00

abstract：:The Andaman and Nicobar Islands, Union Territory of India, are home to six primitive tribes. Studies carried out earlier among these tribes revealed very high rates of hepatitis B infection. We have now studied hepatitis A and E infection among them. A total of 951 serum samples were collected from four accessible tri...

journal_title：Journal of viral hepatitis

authors： Murhekar MV,Sehgal SC,Murhekar KM,Padbhidri SP,Chitambar SD,Arankalle VA

更新日期：2002-07-01 00:00:00

abstract：:Testing and linkage to care are important determinants of hepatitis C virus (HCV) treatment effectiveness. Public health clinics serve populations at high risk of HCV. We investigated their potential to serve as sites for HCV testing, initiation of and linkage to HCV care. Cross-sectional study of patients accessing s...

journal_title：Journal of viral hepatitis

authors： Falade-Nwulia O,Mehta SH,Lasola J,Latkin C,Niculescu A,O'Connor C,Chaulk P,Ghanem K,Page KR,Sulkowski MS,Thomas DL

更新日期：2016-05-01 00:00:00

abstract：:Transcription of p21 was activated in hepatitis C virus (HCV) Core-expressing HepG2 cells where its upstream p53 was stabilized. However, this effect was not absolutely required for the activation of p21 by Core, as demonstrated in Hep3B cells. In addition, an opposite effect on the transcription of p21 was observed i...

journal_title：Journal of viral hepatitis

authors： Kwun HJ,Jang KL

更新日期：2003-07-01 00:00:00

abstract：SUMMARY:Both absolute viral load and log decline in viral load from baseline were found clinically useful in predicting sustained virological response and lack of sustained virological response (non-sustained virological response, NSVR) to treatment. We assessed the clinical utility of hepatitis C virus (HCV) RNA quant...

journal_title：Journal of viral hepatitis

authors： Terrault NA,Pawlotsky JM,McHutchison J,Anderson F,Krajden M,Gordon S,Zitron I,Perrillo R,Gish R,Holodniy M,Friesenhahn M

更新日期：2005-09-01 00:00:00

abstract：:In resource-rich countries, the incidence of and mortality from AIDS has fallen dramatically since the introduction of combination antiretroviral therapy. In contrast, developed countries have observed increases in the public health burden associated with the hepatitis C virus (HCV). We compared past and current trend...

journal_title：Journal of viral hepatitis

authors： Palmateer NE,Hutchinson SJ,McLeod A,Codere G,Goldberg DJ

更新日期：2007-12-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is currently the most important cause of chronic viral hepatitis in the world and one of the most frequent indications for liver transplantation. HCV uses different strategies to evade the innate and adaptive immune response, and this evasion plays a key role in determining viral pers...

journal_title：Journal of viral hepatitis

authors： Fernández-Ponce C,Dominguez-Villar M,Muñoz-Miranda JP,Arbulo-Echevarria MM,Litrán R,Aguado E,García-Cozar F

更新日期：2017-05-01 00:00:00

abstract：:The prevalence of chronic hepatitis C virus (HCV) and the presence of human pegivirus 2 (HPgV-2) have not been examined in Cameroon, although HCV has been associated with HPgV-2 infections previously. Herein we aimed to characterize the burden and genetic diversity of HCV and the presence of HPgV-2 in Cameroon. Retros...

journal_title：Journal of viral hepatitis

authors： Rodgers MA,Holzmayer V,Vallari A,Olivo A,Forberg K,Fuhrman J,Coller KE,Awazi B,Kenmegne Sidje JB,Frankel MB,Berg MG,Mbanya D,Ndembi N,Cloherty GA

更新日期：2019-01-01 00:00:00

abstract：:This study examined the association between chronic HBV or HCV infection and the risk of extrahepatic cancers. A total of 537 103 adults aged ≥20 years without history of cancer were identified from the Korean National Health Insurance Service-National Sample Cohort between 2003 and 2013. The difference in cancer inci...

journal_title：Journal of viral hepatitis

authors： Hong CY,Sinn DH,Kang D,Paik SW,Guallar E,Cho J,Gwak GY

更新日期：2020-09-01 00:00:00

abstract：:A randomized trial was conducted to assess the efficacy of interferon-alpha (IFN) daily in combination with ribavirin in 301 naïve patients with chronic hepatitis C (CHC). Patients were randomized to receive ribavirin 1.2 g daily (QD) for 48 weeks with either IFN 5 MU (thrice weekly) TIW for 8 weeks followed by IFN 3 ...

journal_title：Journal of viral hepatitis

authors： Tassopoulos NC,Ketikoglou I,Tsantoulas D,Raptopoulou M,Hatzis G,Vafiadis I,Sidiropoulos L,Kanatakis S,Anagnostopoulos G,Sypsa V,Hatzakis A,Hellenic Viral Hepatitis Research Network.

更新日期：2003-09-01 00:00:00

abstract：:With the advent of direct-acting antivirals (DAAs), the treatment of chronic hepatitis C virus (HCV) infection (CHC) has been revolutionized. Modern interferon- and potentially also ribavirin-free combinations consisting of 2 or 3 direct-acting antivirals (DAA) promise sustained virological response rates (SVR) of abo...

journal_title：Journal of viral hepatitis

authors： Boesecke C,Rockstroh JK

更新日期：2015-01-01 00:00:00

abstract：SUMMARY:Noninvasive markers that accurately follow changes in fibrosis may provide alternatives to liver biopsy for assessment of histological endpoints of antiviral therapy in chronic hepatitis C (CHC). This study compared two commercially available serum marker panels (HCV FibroSURE and FIBROSpect II) during interfer...

journal_title：Journal of viral hepatitis

authors： Patel K,Benhamou Y,Yoshida EM,Kaita KD,Zeuzem S,Torbenson M,Pulkstenis E,Subramanian GM,McHutchison JG

更新日期：2009-03-01 00:00:00

abstract：:Hepatitis C virus (HCV) and hepatitis B virus (HBV) frequently coinfect and persist long after clinical resolution. We assessed the incidence of low-level (occult) HCV infection (OCI) after sustained virological response (SVR) to standard anti-HCV therapy in individuals with or without past exposure to HBV to recogniz...

journal_title：Journal of viral hepatitis

authors： Pham TN,Coffin CS,Churchill ND,Urbanski SJ,Lee SS,Michalak TI

更新日期：2012-02-01 00:00:00

abstract：:The aim of this study was to evaluate the pharmacokinetic profile of daclatasvir (DCV) and asunaprevir (ASV) dual therapy in haemodialysis patients infected with hepatitis C virus (HCV). Eighteen haemodialysis patients and 54 patients with normal renal function were treated with DCV and ASV dual therapy for 24 weeks. ...

journal_title：Journal of viral hepatitis

authors： Kawakami Y,Imamura M,Ikeda H,Suzuki M,Arataki K,Moriishi M,Mori N,Kokoroishi K,Katamura Y,Ezaki T,Ueno T,Ide K,Masaki T,Ohdan H,Chayama K

更新日期：2016-11-01 00:00:00