Dissociable contributions of MRI volume reductions of superior temporal and fusiform gyri to symptoms and neuropsychology in schizophrenia.

abstract：BACKGROUND:Anomalies in visual and auditory perception represent an important aspect of the symptomatic manifestation of schizophrenia (ScZ). However, there are currently no instruments available that allow the assessment of the full range of auditory and visual abnormalities using a self-report measure. METHODS:We de...

journal_title：Schizophrenia research

authors： Nikitova N,Keane BP,Demmin D,Silverstein SM,Uhlhaas PJ

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Verbal and visual memory deficits are prominent trait markers for schizophrenia, with impairments also observed in first-degree relatives [Snitz, B.E., Macdonald, A.W., 3rd, & Carter, C.S. (2006). Cognitive deficits in unaffected first-degree relatives of schizophrenia patients: a meta-analytic review of put...

journal_title：Schizophrenia research

authors： Skelley SL,Goldberg TE,Egan MF,Weinberger DR,Gold JM

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:The concept of dose equivalence of depot medication is important for many scientific and clinical purposes. METHODS:A systematic literature search on four second-generation antipsychotics available as long-acting injectable drugs and haloperidol was conducted. We used the minimum effective dose method which...

journal_title：Schizophrenia research

authors： Rothe PH,Heres S,Leucht S

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Proton magnetic resonance spectroscopy (1H-MRS) studies of schizophrenia suggest an effect of the disease or of antipsychotic medications on brain N-acetyl aspartate (NAA), a marker of neuronal viability. We studied in the rat the effect of antipsychotic drugs on NAA in several brain regions where NAA reduct...

journal_title：Schizophrenia research

authors： Bustillo J,Wolff C,Myers-y-Gutierrez A,Dettmer TS,Cooper TB,Allan A,Lauriello J,Valenzuela CF

更新日期：2004-01-01 00:00:00

abstract：:Non-compliance problems may rise to 50% among patients undergoing neuroleptic treatment. There are no direct measures available to predict compliance, if previous non-compliance is not taken into account. Attitudes towards neuroleptic treatment and insight into psychotic symptoms may vary during the course of the trea...

journal_title：Schizophrenia research

authors： Kampman O,Lehtinen K,Lassila V,Leinonen E,Poutanen O,Koivisto A

更新日期：2000-10-27 00:00:00

abstract：BACKGROUND:Aberrations in body perception are common in psychotic disorders. The insula and temporoparietal junction (TPJ) are involved in body ownership and spatial perception suggesting that abnormal structure of these regions might be related to the expression of perceptual aberrations in psychosis. METHODS:58 indi...

journal_title：Schizophrenia research

authors： Brosey EA,Woodward ND

更新日期：2017-01-01 00:00:00

abstract：:By employing a novel semi-parametric extrapolation method, the life expectancies after the first hospitalization for schizophrenia and the associated lifetime healthcare expenditures were both estimated. Based on the linkage between the National Health Insurance Research Database and the National Mortality Registry of...

journal_title：Schizophrenia research

authors： Lêng CH,Chou MH,Lin SH,Yang YK,Wang JD

更新日期：2016-03-01 00:00:00

abstract：:Earlier studies suggest that social competence has a higher predictive value for vocational outcome than psychopathology. These studies, however, show methodological shortcomings, including the fact that the instruments used for assessing social competence, psychopathology and work performance are strongly interrelate...

journal_title：Schizophrenia research

authors： Hoffmann H,Kupper Z

更新日期：1997-01-17 00:00:00

abstract：:Schizophrenia is a severe psychiatric disorder with lifetime prevalence of ~1% worldwide. A genotyping study was conducted using a custom panel of Illumina 1536 SNPs in 840 schizophrenia cases and 876 controls (351 patients and 385 controls from North India; and 436 patients, 401 controls and 143 familial samples with...

journal_title：Schizophrenia research

authors： Jajodia A,Kaur H,Kumari K,Gupta M,Baghel R,Srivastava A,Sood M,Chadda RK,Jain S,Kukreti R

更新日期：2015-03-01 00:00:00

abstract：:Deficits in emotion perception are common in people with schizophrenia and current research has focused on improving these deficits. In our previous research, we demonstrated that directing attention to salient facial features via attention shaping can improve these deficits among inpatients. In this study, we examine...

journal_title：Schizophrenia research

authors： Combs DR,Chapman D,Waguspack J,Basso MR,Penn DL

更新日期：2011-04-01 00:00:00

abstract：:Motivational deficits in patients with schizophrenia adversely affect various domains of daily living. This symptom in everyday life situations manifests in a complex behavioral pattern whose root cannot be simplified to an impaired reward-motivation scheme. This study aimed to identify impairment of the salience netw...

journal_title：Schizophrenia research

authors： Kim BH,Shin YB,Kyeong S,Lee SK,Kim JJ

更新日期：2018-07-01 00:00:00

abstract：:Morphologic abnormalities of the insular cortex have been described in psychotic disorders such as schizophrenia, but it remains unclear whether these changes predate the onset of psychosis or develop progressively over the course of illness. In this study, we used magnetic resonance imaging to investigate the gray ma...

journal_title：Schizophrenia research

authors： Takahashi T,Wood SJ,Yung AR,Phillips LJ,Soulsby B,McGorry PD,Tanino R,Zhou SY,Suzuki M,Velakoulis D,Pantelis C

更新日期：2009-06-01 00:00:00

abstract：:Levels of the histamine metabolites, tele-methylhistamine (t-MH) and tele-methylimidazoleacetic acid (t-MIAA), and metabolites of other aminergic transmitters and of norepinephrine were measured in cerebrospinal fluid of 36 inpatients with chronic schizophrenia and eight controls. The mean t-MH level from controls was...

journal_title：Schizophrenia research

authors： Prell GD,Green JP,Kaufmann CA,Khandelwal JK,Morrishow AM,Kirch DG,Linnoila M,Wyatt RJ

更新日期：1995-01-01 00:00:00

abstract：:Psychotic disorders are characterized by auditory verbal hallucinations (AVHs), and research has shown that AVHs are linked to deficits in working memory. Our understanding of AVHs across the psychosis continuum is limited. To date, little research has tested whether hallucination proneness (HP) is linked with abnorma...

journal_title：Schizophrenia research

authors： Gupta T,DeVylder JE,Auerbach RP,Schiffman J,Mittal VA

更新日期：2018-05-01 00:00:00

abstract：:Previous diffusion tensor imaging (DTI) studies have shown structural abnormalities of the cingulum bundle (CB) in patients with schizophrenia. However, regional specificity and functional relevance of the pregenual and dorsal CB subdivisions has not been fully studied. In the current study, 31 patients with schizophr...

journal_title：Schizophrenia research

authors： Takei K,Yamasue H,Abe O,Yamada H,Inoue H,Suga M,Muroi M,Sasaki H,Aoki S,Kasai K

更新日期：2009-10-01 00:00:00

abstract：:Sleep disturbances have been reliably reported in patients with schizophrenia, thus suggesting that abnormal sleep may represent a core feature of this disorder. Traditional electroencephalographic studies investigating sleep architecture have found reduced deep non-rapid eye movement (NREM) sleep, or slow wave sleep ...

journal_title：Schizophrenia research

authors： Ferrarelli F,Tononi G

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Childhood and adolescence represent the periods during which hallucinatory experiences occur at the greatest prevalence, and also constitute a critical window of vulnerability for the pathogenesis of psychotic disorders. The longitudinal course of hallucinatory experiences during late childhood and adolescen...

journal_title：Schizophrenia research

authors： Rubio JM,Sanjuán J,Flórez-Salamanca L,Cuesta MJ

更新日期：2012-07-01 00:00:00

abstract：:Theory of mind (ToM) is the ability to understand mental states of others and it is crucial for building sensitivity to other persons or events. Measuring ToM is important for understanding and rehabilitating social cognitive impairments in persons with schizophrenia. The Social Attribution Task-Multiple Choice (SAT-M...

journal_title：Schizophrenia research

authors： Lee HS,Corbera S,Poltorak A,Park K,Assaf M,Bell MD,Wexler BE,Cho YI,Jung S,Brocke S,Choi KH

更新日期：2018-11-01 00:00:00

abstract：:Schizophrenia and at-risk populations are suggested to exhibit referential cohesion deficits in language production (e.g., producing fewer pronouns or nouns that clearly link to concepts from previous sentences). Much of this work has focused on transcribed speech samples, while no work to our knowledge has examined r...

journal_title：Schizophrenia research

authors： Gupta T,Hespos SJ,Horton WS,Mittal VA

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:Recent years have witnessed growing interest in the role of the social environment in the development and outcomes of schizophrenia. We investigated whether neighborhood characteristics are associated with two important prognostic factors in early-course psychosis, age at onset of psychosis (AOP) and duration...

journal_title：Schizophrenia research

authors： Ku BS,Pauselli L,Manseau M,Compton MT

更新日期：2020-04-01 00:00:00

abstract：:Many neuropsychological studies have described deficits of memory and executive functions in patients with schizophrenia, and the severity of these deficits seems to be determinant in predicting the community outcome of these patients [Schizophr. Bull. 26 (2000) 119]. However, neuropsychological evaluation does not pr...

journal_title：Schizophrenia research

authors： Semkovska M,Bédard MA,Godbout L,Limoge F,Stip E

更新日期：2004-08-01 00:00:00

abstract：:Twenty-five schizophrenic patients diagnosed by DSM-III-R underwent event-related potentials and magnetic resonance imaging scans. Latency and amplitude of P300 waveform were measured using an auditory odd-ball paradigm. Anterior and posterior volumes of the superior temporal gyrus and medial temporal structure were m...

journal_title：Schizophrenia research

authors： Kawasaki Y,Maeda Y,Higashima M,Nagasawa T,Koshino Y,Suzuki M,Ide Y

更新日期：1997-08-29 00:00:00

abstract：:This study was a preliminary open clinical trial aimed at exploring the hypothesis that estrogen may provide protection against schizophrenia in women. Eleven women with acute psychotic symptoms, as scored on the BPRS, SAPS and SANS, had 0.02 mg estradiol added to neuroleptic treatment for eight weeks. Their response ...

journal_title：Schizophrenia research

authors： Kulkarni J,de Castella A,Smith D,Taffe J,Keks N,Copolov D

更新日期：1996-07-05 00:00:00

abstract：BACKGROUND:Higher cognitive dysfunction, lower perceptual disturbance and its relation to the structures that implicate such processes have been considered as key features in patients with schizophrenia. However, little is known about the relationship between perceptual processing and structural deficits in ultra-high-...

journal_title：Schizophrenia research

authors： Shin KS,Jung WH,Kim JS,Jang JH,Hwang JY,Chung CK,Kwon JS

更新日期：2012-09-01 00:00:00

abstract：:Schizophrenia is associated with significant brain abnormalities, including changes in brain metabolites as measured by proton magnetic resonance spectroscopy (MRS). What remains unclear is the extent to which these changes are a consequence of the emergence of psychotic disorders or the result of treatment with antip...

journal_title：Schizophrenia research

authors： Wood SJ,Berger GE,Wellard RM,Proffitt T,McConchie M,Velakoulis D,McGorry PD,Pantelis C

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Psychotic-like experiences (PLEs) during adolescence are not uncommon and potentially represent a clinical and public health concern. A greater understanding of their aetiology and patterns of change over time is needed. We aimed to describe trajectories of PLEs during adolescence, and examine their associat...

journal_title：Schizophrenia research

authors： Thapar A,Heron J,Jones RB,Owen MJ,Lewis G,Zammit S

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:In schizophrenic psychoses, the normal sexual dimorphism of the brain has been shown to be disrupted or even reversed. Little is known, however, at what time point in emerging psychosis this occurs. We have therefore examined, if these alterations are already present in the at-risk mental state (ARMS) for ps...

journal_title：Schizophrenia research

authors： Egloff L,Lenz C,Studerus E,Harrisberger F,Smieskova R,Schmidt A,Huber C,Simon A,Lang UE,Riecher-Rössler A,Borgwardt S

更新日期：2018-09-01 00:00:00

abstract：:Estrogen has been shown in animal studies to modulate both the dopamine and serotonin neurotransmitter systems - the main neurotransmitters implicated in the pathogenesis of schizophrenia. A double blind, 28 day, placebo-controlled study was conducted with three groups of women of child-bearing age (N=12 in each group...

journal_title：Schizophrenia research

authors： Kulkarni J,Riedel A,de Castella AR,Fitzgerald PB,Rolfe TJ,Taffe J,Burger H

更新日期：2001-03-01 00:00:00

abstract：:Outcomes for people with schizophrenia-spectrum disorders (SSDs) are generally poor, making it important to understand risk states and illness transition. The network approach, which conceptualizes psychopathology as a network of causally interacting symptoms, may hold promise in this regard. Here, we present a networ...

journal_title：Schizophrenia research

authors： Dodell-Feder D,Saxena A,Rutter L,Germine L

更新日期：2019-06-01 00:00:00

abstract：:The aim of this study is to compare the neurocognitive functions in individuals with clinical or genetic risk for psychosis, in patients with first-episode schizophrenia (FES) and in healthy controls. We compared cognitive functions of 52 individuals at ultra high risk (UHR) for psychosis, 53 patients with FES, their ...

journal_title：Schizophrenia research

authors： Üçok A,Direk N,Koyuncu A,Keskin-Ergen Y,Yüksel Ç,Güler J,Karadayı G,Akturan E,Devrim-Üçok M

更新日期：2013-12-01 00:00:00