Abstract:
:Most studies investigating articular cartilage changes use global parameters and neglect the large topological variation in the response of cartilage to immobilization and remobilization. We hypothesized a registration-based semi-automatic segmentation method would be highly reproducible to detect local changes in patellar articular cartilage thickness. We also hypothesized thinning of the cartilage is detectable in the smaller subregions of the patella in patients with a spinal cord injury (SCI) and the use of difference maps would allow us to detect early local thinning of the patellar cartilage. To determine the reproducibility, magnetic resonance images of the knee of seven healthy volunteers were acquired four times. Longitudinal changes were measured in the knees of seven patients with SCI as soon as possible, 6 months, and 12 months after the injury. Thickness maps and morphologic parameters for the cartilage of the patella and the four sub-regions were computed. The individual difference maps of 43% of the patients showed local areas of substantial thinning 6 and 12 months after injury.
journal_name
Clin Orthop Relat Resjournal_title
Clinical orthopaedics and related researchauthors
Vanwanseele B,Pirnog C,Székely G,Stüssi Edoi
10.1097/BLO.0b013e3180308431subject
Has Abstractpub_date
2007-03-01 00:00:00pages
98-102eissn
0009-921Xissn
1528-1132journal_volume
456pub_type
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journal_title:Clinical orthopaedics and related research
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journal_title:Clinical orthopaedics and related research
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journal_title:Clinical orthopaedics and related research
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journal_title:Clinical orthopaedics and related research
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journal_title:Clinical orthopaedics and related research
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journal_title:Clinical orthopaedics and related research
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journal_title:Clinical orthopaedics and related research
pub_type: 杂志文章
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journal_title:Clinical orthopaedics and related research
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journal_title:Clinical orthopaedics and related research
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journal_title:Clinical orthopaedics and related research
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journal_title:Clinical orthopaedics and related research
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journal_title:Clinical orthopaedics and related research
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