The relation of germ cells per tubule in testes, serum inhibin B and FSH in cryptorchid boys.

Abstract:

:At bilateral orchiopexy bilateral biopsies may be indicated to determine fertility potential. It is currently unknown if the serum inhibin B levels at time of orchiopexy reflect the testicular status of the bilaterally cryptorchid child. The aim of this study was to relate the results of inhibin B and FSH measurements with testicular biopsy parameters in bilateral cryptorchid boys. Included were 25 boys with bilateral cryptorchidism, median 2.5 years (9 months to 5.5 years) at surgery for bilateral cryptorchidism with simultaneous testicular biopsies, and blood sample for inhibin B and FSH. The number of spermatogonia and gonocytes was measured in 100 tubular transverse sections, the S/T and the mean-S/T of the patient was found, and expressed as percent of lowest normal value. Inhibin B and FSH were measured and related to age-specific values. Forty percent (10/25) of the patients had very low mean-S/T (mean-S/T<10% of lowest normal-value). Inhibin B was decreased in 24% (6/25) of the patients, all with decreased mean-S/T, predominantly with a mean-S/T<10% of lowest normal-value (p<0.05). There was a negative correlation between inhibin B and FSH (p<0.05). In cases of mean-S/T<10% of lowest normal-value and decreased inhibin B, we found increased FSH in 9% (2/22) of the patients and hypergonadotropic hypogonadism was suspected. Low FSH was found in 5% (1/22) of the patients and hypogonadotropic hypogonadism was suspected. Low inhibin B predicts a serious condition in respect of infertility. Low FSH and inhibin B indicates examination for hypogonadotropic hypogonadism. In bilateral cryptorchid boys inhibin B levels correlated negatively to FSH.

journal_name

Pediatr Surg Int

authors

Cortes D,Thorup J,Hogdall E,Norgaard-Pedersen B,Petersen BL,Hogdall C

doi

10.1007/s00383-006-1839-9

subject

Has Abstract

pub_date

2007-02-01 00:00:00

pages

163-9

issue

2

eissn

0179-0358

issn

1437-9813

journal_volume

23

pub_type

杂志文章
  • Benefit of preformed silos in the management of gastroschisis.

    abstract::Gastroschisis is traditionally managed by primary closure (PC) or delayed closure after surgical silo placement. Bedside insertion of preformed silos (PFS) and delayed closure has become more widespread, although its benefits remain unclear. To identify differences in outcome of infants managed with PFS compared with ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-007-2004-9

    authors: Allotey J,Davenport M,Njere I,Charlesworth P,Greenough A,Ade-Ajayi N,Patel S

    更新日期:2007-11-01 00:00:00

  • A review of congenital lung malformations with a simplified classification system for clinical and research use.

    abstract:PURPOSE:Congenital lung abnormalities are rare malformations increasingly detected early by prenatal ultrasound. Whether management of these frequently asymptomatic lesions should be surgical or conservative is an unresolved issue. The necessary prospective studies are limited by the absence of a widely accepted practi...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章,评审

    doi:10.1007/s00383-017-4062-y

    authors: Seear M,Townsend J,Hoepker A,Jamieson D,McFadden D,Daigneault P,Glomb W

    更新日期:2017-06-01 00:00:00

  • Feasibility of perineal sagittal approaches in patients without anorectal malformations.

    abstract::Perineal sagittal approaches (posterior sagittal anorectoplasty and anterior and posterior sagittal transanorectal approaches) allow complete anatomic exposure of the perineum and lower pelvis. Moreover, they reduce the risk of damaging important structures because the incision is led in the midline. Therefore, many s...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-004-1295-3

    authors: Pini Prato A,Martucciello G,Torre M,Jasonni V

    更新日期:2004-10-01 00:00:00

  • Posterior urethral valves: the scenario in a developing center.

    abstract::We have reviewed 233 patients with posterior urethral valves treated in a single center in Calcutta, India, over the last 20 years: 37 were neonates, 75 were between 1 and 12 months, 88 were between 1 and 5 years, and 33 were more than 5 years old when first seen. The clinical presentation and methods employed in diag...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s003830000495

    authors: Chatterjee SK,Banerjee S,Basak D,Basu AK,Chakravarti AK,Chatterjee US,Haque J

    更新日期:2001-01-01 00:00:00

  • The use of mesenchymal stem cells in bladder augmentation.

    abstract:PURPOSE:To compare integration of bladder acellular matrix (BAM) with the bladder when seeded with mesenchymal stem cells (MSC) and when MSC are injected intravenously (IV). METHODS:MSCs were isolated from bone marrow of EPM-1 Wistar male rats. Female rats were distributed into: Group A-BAM augmentation; Group B-BAM a...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-014-3465-2

    authors: Leite MT,Freitas-Filho LG,Oliveira AS,Semedo-Kuriki P,Laks M,Arias VE,Peixoto PS

    更新日期:2014-04-01 00:00:00

  • Presenilin genes are downregulated during somitogenesis in the cadmium-induced omphalocele chick model.

    abstract:PURPOSE:Although the precise pathogenesis of ventral body wall (VBW) defects is not clearly understood, it has recently postulated that disruption of somite development during early embryogenesis may cause failure of proper VBW formation. The administration of cadmium (Cd) after 60 h of incubation induces omphalocele s...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-011-2994-1

    authors: Doi T,Fujiwara N,Puri P,Bannigan J,Thompson J

    更新日期:2012-02-01 00:00:00

  • A new instrument for suction rectal biopsy in the diagnosis of Hirschsprung's disease.

    abstract::A new instrument for suction rectal biopsy in infants suspected of having Hirschsprung's disease is described that can be completely dismantled, physically cleaned, lubricated, and heat-sterilised. These attributes are new and are absolutely critical today. The instrument has been used in 60 patients (ca. 180 biopsies...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/BF01194812

    authors: Freeman JK

    更新日期:1997-01-01 00:00:00

  • Urgent distal splenorenal shunt in low-body weight patients.

    abstract::The authors report two patients with extrahepatic portal hypertension and repeated massive bleeding from esophageal varices who underwent urgent distal splenorenal shunting (DSRS) after having proved refractory to medical treatment, endoscopic sclerotherapy, and ligation of esophageal varices. Their ages and weights w...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s003830100014

    authors: Vila Carbó JJ,Ibáñez V,Lluna J,Roca A,Genovés I,García-Sala C

    更新日期:2001-11-01 00:00:00

  • A transvesical approach to mullerian duct remnants

    abstract::Surgical extirpation is the treatment of choice for symptomatic mullerian duct remnants (prostatic utricle, PU), and several surgical approaches have been described for the treatment of this pathology. A group of 11 patients with symptomatic PU were observed and treated. Associated anomalies included proximal or penos...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:

    authors: Benedetto VD,Bagnara V V,Guys JM,Meyrat JM,Monfort G

    更新日期:1997-03-21 00:00:00

  • Modified PATIO repair for urethrocutaneous fistula post-hypospadias repair: operative technique and outcomes.

    abstract:BACKGROUND:To describe a modification of PATIO repair for urethrocutaneous fistula repair and evaluate its outcome. METHODS:We studied 15 boys who underwent modified PATIO repair from Jan 2010 to Sept 2015. Parameters studied included age, type of hypospadias, age at first urethroplasty, hypospadias repair technique, ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-016-3983-1

    authors: Rathod K,Loyal J,More B,Rajimwale A

    更新日期:2017-01-01 00:00:00

  • Management of nocturnal enuresis in children with desmopressin and bladder physiotherapy.

    abstract::In the last 2 years, 29 children with nocturnal enuresis were treated in the outpatient departments of the Departments of Urology and Pediatric Surgery of the Aristotle University, Thessaloniki. There were 22 boys and 7 girls aged 7 to 12 years. The clinical examination was normal in all cases. All children had underg...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s003830050317

    authors: Yannakoyorgos K,Ioannides E,Zahariou A,Anagnostopoulos D,Kasselas V,Kalinderis A

    更新日期:1998-04-01 00:00:00

  • Management of large primary spontaneous pneumothorax in children: radiological guidance, surgical intervention and proposed guideline.

    abstract:PURPOSE:Primary spontaneous pneumothorax (PSP) is managed in accordance with the adult British Thoracic Society (BTS) guidelines due to lack of paediatric evidence and consensus. We aim to highlight the differences and provide a best practice surgical management strategy for PSP based on experience of two major paediat...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-015-3787-8

    authors: Soccorso G,Anbarasan R,Singh M,Lindley RM,Marven SS,Parikh DH

    更新日期:2015-12-01 00:00:00

  • Laparotomy or drain for perforated necrotizing enterocolitis: who gets what and why?

    abstract::Between 1974 and 1988, 86 newborns with perforated necrotizing enterocolitis (NEC) were treated by either laparotomy (usually involving a bowel resection and a temporary stoma) or a peritoneal drain under local anesthesia. The survival of babies in the laparotomy group was 57% versus 59% in the drained group. However,...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:

    authors: Azarow KS,Ein SH,Shandling B,Wesson D,Superina R,Filler RM

    更新日期:1997-02-01 00:00:00

  • Cajal-like cells in the upper urinary tract: comparative study in various species.

    abstract::The interstitial cells of Cajal (ICC) play an important role in the control of gut motility. The recognition that the ICC cell membrane harbors the c-kit receptor (CD117) sparked rapid advancement in ICC research on the gut and certain pathologies using immunochemical and molecular methods. The question arises whether...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-004-1314-4

    authors: Metzger R,Schuster T,Till H,Franke FE,Dietz HG

    更新日期:2005-03-01 00:00:00

  • Retrocaval ureter in children: a report of two cases.

    abstract::Retrocaval ureter is a relatively rare anomaly that usually manifests in the third or fourth decades. Symptoms are due to ureteric obstruction, either extrinsic by the abnormal inferior vena cava (IVC), or intrinsic ureteric hypoplasia. Surgery is needed for symptomatic cases and involves transection and relocation of...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-003-1038-x

    authors: Soundappan SV,Barker AP

    更新日期:2004-02-01 00:00:00

  • Left-sided gastroschisis and pseudoexstrophy: a rare combination of anomalies.

    abstract::Pseudoexstrophy is a rare variant of the exstrophy/epispadias complex, comprised of the musculoskeletal defects of classic exstrophy but with an intact bladder and urethra. We present a case of a neonate with left-sided gastroschisis and pseudoexstrophy, the first reported combination of these two anomalies. The anoma...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-004-1217-4

    authors: Orpen NM,Mathievathaniy M,Hitchcock R

    更新日期:2004-07-01 00:00:00

  • Complete surgical resection plus chemotherapy prolongs survival in children with stage 4 neuroblastoma.

    abstract::The factors that affect survival in patients with stage 4 neuroblastoma vary. Several prospective and retrospective studies have provided conflicting conclusions regarding the benefit of combining aggressive chemotherapy with complete surgical resection. We analyzed our experience to evaluate the effect of complete su...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-004-1353-x

    authors: Koh CC,Sheu JC,Liang DC,Chen SH,Liu HC

    更新日期:2005-02-01 00:00:00

  • Rupture of the right hemidiaphragm due to blunt trauma in children: a diagnostic dilemma.

    abstract::The diagnosis of right-sided diaphragmatic rupture (RDR) due to blunt abdominal trauma is often missed in the acute setting, especially in the absence of other thoracoabdominal injuries. We describe two such children. The problems associated with the diagnosis and management of RDR are discussed to emphasize the need ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s003830100686

    authors: Sharma AK,Kothari SK,Gupta C,Menon P,Sharma A

    更新日期:2002-03-01 00:00:00

  • Universal distribution of c-kit-positive cells in different types of Hirschsprung's disease.

    abstract::Interstitial cells of Cajal (ICCs) have been reported to play the role of a pacemaker in regulating bowel motility. The relationship between neurons and ICCs, however, remains unclear. Hirschsprung's disease (HD) is an ideal model for investigating this relationship. The operated specimens obtained from 6 short and 3 ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-002-0931-z

    authors: Taguchi T,Suita S,Masumoto K,Nada O

    更新日期:2003-06-01 00:00:00

  • The management of nephroblastoma with cavo-atrial disease at presentation: experience from a developing country.

    abstract:PURPOSE:To describe the management of cavoatrial extension of nephroblastoma in a developing country. PATIENTS AND METHODS:Of 406 consecutive children with Wilms tumour, 40 (10%) presented with tumour extension into the inferior vena cava (IVC) (30), right atrium or right ventricle and form the inception cohort. Of th...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-010-2667-5

    authors: Hadley GP,Sheik-Gafoor MH,Buckels NJ

    更新日期:2010-12-01 00:00:00

  • Pulmonary artery size has prognostic value in low birth weight infants with congenital diaphragmatic hernia.

    abstract:AIM:The aim of this study was to examine the relationship between birth weight, pulmonary artery (PA) size, and outcome in congenital diaphragmatic hernia (CDH) to establish if PA size has prognostic value. METHODS:The subjects for this study were 39 consecutive left-sided CDH patients treated at our institution accor...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-011-2899-z

    authors: Takahashi T,Koga H,Tanaka T,Shoji H,Takeda S,Shimizu T,Lane GJ,Yamataka A,Okazaki T

    更新日期:2011-08-01 00:00:00

  • Meatal and corpus spongiosum advancement: a better technique for distal hypospadias repair.

    abstract:OBJECTIVE:Several procedures have been described for repair of distal hypospadias. However, these are not without any complications. Corpus spongiosum advancement is a new technique employed in our patients for distal hypospadias repair with excellent clinical outcome and no post-operative complications. PATIENTS AND ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-013-3292-x

    authors: Dutta HK

    更新日期:2013-06-01 00:00:00

  • Postgraduate medical education in paediatric surgery: videoconferencing--a possible solution for Africa?

    abstract::Africa faces a triple burden of disease; HIV, tuberculosis and malaria. Despite this, its population is expected to double over the next 45 years. There is a dire shortage of medical specialists and many countries lack suitably qualified doctors to train medical specialists. Videoconferencing offers the opportunity to...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-007-2085-5

    authors: Hadley GP,Mars M

    更新日期:2008-02-01 00:00:00

  • Separation of ischiopagus tetrapus conjoined twins in the Sultanate of Oman.

    abstract::Premature male ischiopagus tetrapus twins weighing 2.2 kg were born unexpectedly. They required initial ventilation for respiratory distress syndrome and an emergency laparotomy for intestinal obstruction at 10 days of age. At 8 months of age, formal separation was carried out. Primary skin closure was possible withou...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/BF01372144

    authors: Freeman NV,Fahr J,Al-Khusaiby S

    更新日期:1997-04-01 00:00:00

  • Perforated tubular duplication of the transverse colon: a rare cause of meconium peritonitis with prenatal diagnosis.

    abstract::The transverse colon is an exceptional location of intestinal duplication. Perforated duplications are rarely described in neonates. Meconium peritonitis (MP) can originate from prenatal perforated intestinal duplication. The authors report a case of a baby girl with prenatal diagnosis of MP. Rapid worsening of clinic...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-004-1349-6

    authors: Piolat C,N'die J,Andrini P,Althuser M,Jouk PS,Jacquier C,Dyon JF

    更新日期:2005-02-01 00:00:00

  • Surgical jejunostomy and radiological gastro-jejunostomy tube feeding in children: risks, benefits and nutritional outcomes.

    abstract:PURPOSE:Radiologically inserted gastrojejunal tubes (RGJ) and surgical jejunostomy (SJ) are established modes of jejunal feeding. The aim of the study is to review nutritional outcomes, complications and the practical consideration to enable patients and carers to make informed choice. METHODS:Retrospective review of ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-018-4303-8

    authors: Singh RR,Eaton S,Roebuck DJ,Barnacle AM,Chippington S,Cross KMK,De Coppi P,Curry JI

    更新日期:2018-09-01 00:00:00

  • Anomalies associated with oesophageal atresia in Asians and Europeans.

    abstract::Oesophageal atresia (OA) is often associated with anomalies of other systems. The genetic contribution to the formation of the VACTERL association is not clear. The objective of this study was to evaluate the incidence of associated anomalies in two different racial populations. The associated anomalies in neonates wi...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s003830100692

    authors: van Heurn LW,Cheng W,de Vries B,Saing H,Jansen NJ,Kootstra G,Tam PK

    更新日期:2002-05-01 00:00:00

  • Reappraisal of the role of the bilioenteric conduit in the pathogenesis of postoperative cholangitis.

    abstract::The incidence of postoperative cholangitis has changed very little despite progressive improvement in the treatment of biliary atresia. The role of the bilioenteric conduit in its pathogenesis is still uncertain. A retrospective study of 39 patients undergoing either a conventional Kasai operation (group 1, n = 20) or...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s003830050008

    authors: Chuang JH,Lee SY,Shieh CS,Chen WJ,Chang NK

    更新日期:2000-01-01 00:00:00

  • Focal nodular hyperplasia in a child with Beckwith-Wiedemann syndrome.

    abstract::Beckwith-Wiedemann Syndrome (BWS) is associated with somatic overgrowth and a high risk for embryonal tumors, including hepatoblastoma, a highly malignant liver tumor of childhood. Focal nodular hyperplasia (FNH), on the other hand, is a benign tumor of the liver that is uncommon in childhood. Herein we describe a cas...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-005-1469-7

    authors: Bordeianou L,Ryan DP,Goldstein AM

    更新日期:2005-09-01 00:00:00

  • Effect of Lomodex-MgSO(4) in the prevention of reperfusion injury following unilateral testicular torsion: an experimental study in rats.

    abstract::Fertility in patients treated for unilateral testicular torsion has been shown to be significantly reduced in all the reported series to date, implying that the present-day treatment requires further refinement in the form of adjunct pharmacotherapeutic intervention (Lomodex and MgSO(4)) in addition to scrotal explora...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-004-1317-1

    authors: Adivarekar PK,Bhagwat SS,Raghavan V,Bandivdekar AH

    更新日期:2005-03-01 00:00:00