Abstract:
:At bilateral orchiopexy bilateral biopsies may be indicated to determine fertility potential. It is currently unknown if the serum inhibin B levels at time of orchiopexy reflect the testicular status of the bilaterally cryptorchid child. The aim of this study was to relate the results of inhibin B and FSH measurements with testicular biopsy parameters in bilateral cryptorchid boys. Included were 25 boys with bilateral cryptorchidism, median 2.5 years (9 months to 5.5 years) at surgery for bilateral cryptorchidism with simultaneous testicular biopsies, and blood sample for inhibin B and FSH. The number of spermatogonia and gonocytes was measured in 100 tubular transverse sections, the S/T and the mean-S/T of the patient was found, and expressed as percent of lowest normal value. Inhibin B and FSH were measured and related to age-specific values. Forty percent (10/25) of the patients had very low mean-S/T (mean-S/T<10% of lowest normal-value). Inhibin B was decreased in 24% (6/25) of the patients, all with decreased mean-S/T, predominantly with a mean-S/T<10% of lowest normal-value (p<0.05). There was a negative correlation between inhibin B and FSH (p<0.05). In cases of mean-S/T<10% of lowest normal-value and decreased inhibin B, we found increased FSH in 9% (2/22) of the patients and hypergonadotropic hypogonadism was suspected. Low FSH was found in 5% (1/22) of the patients and hypogonadotropic hypogonadism was suspected. Low inhibin B predicts a serious condition in respect of infertility. Low FSH and inhibin B indicates examination for hypogonadotropic hypogonadism. In bilateral cryptorchid boys inhibin B levels correlated negatively to FSH.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Cortes D,Thorup J,Hogdall E,Norgaard-Pedersen B,Petersen BL,Hogdall Cdoi
10.1007/s00383-006-1839-9subject
Has Abstractpub_date
2007-02-01 00:00:00pages
163-9issue
2eissn
0179-0358issn
1437-9813journal_volume
23pub_type
杂志文章abstract::Parasitic infestations, mainly enterobiasis and amoebiasis, and poor toilet training practices are commonly associated with rectal prolapse in developing countries. Injection sclerotherapy is one of the commonly used modalities for treating partial rectal prolapse in children. Various materials are available for such ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-004-1197-4
更新日期:2004-05-01 00:00:00
abstract::The transanal endorectal pull-through (TAEPT) procedure is now widely performed for Hirschsprung's disease (HD), however, the colorectal function after TAEPT has not yet been adequately assessed. We evaluated the postoperative clinical outcome and colorectal function based on lower colonic manometry after TAEPT. Twent...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-1981-z
更新日期:2007-10-01 00:00:00
abstract:PURPOSE:Laparoscopic-assisted anorectoplasty (LAARP) is considered to benefit the patients with vesico-prostatic fistula. The aim of this study is to present the details of our LAARP technique for improving the short- and long-term outcomes in the patients with high and intermediate types of anorectal malformations (AR...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-019-04614-x
更新日期:2020-03-01 00:00:00
abstract::The Thomsen-Friedenreich cryptantigen (TCA) is located on the surface of all red cells, but is concealed by a layer of neuraminic acid. When bacteria that produce neuraminidase disrupt this coating, the TCA can be exposed and activated. If blood products containing antibody to the TCA are subsequently administered, ha...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050488
更新日期:1998-12-01 00:00:00
abstract:PURPOSE:With the widespread use of the obstetrical ultrasound, identification of a fetal suprarenal mass has become more common. Most of these masses prove to be congenital neuroblastomas (CNB), but the diagnosis is often confused with other benign lesions and the postnatal management remains to be controversial. METH...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-009-2531-7
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Although it is virtually impossible to formulate a scheme that can satisfactorily collect all different types of vaginal malformations, a simple classification would be of a considerable value and would permit logical operative decisions. Many classifications of anomalies of uterus and vagina have been propo...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-012-3121-7
更新日期:2012-08-01 00:00:00
abstract::Measurement of testicular volume is a more readily available method of estimating spermatogenesis in adolescence. Traditionally, testicular volumes have been measured with different type of orchidometers or calipers. The most widely used orchidometer is the Prader orchidometer introduced in 1966. This type of orchidom...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-005-1470-1
更新日期:2005-07-01 00:00:00
abstract::Congenital mesoblastic nephroma (CMN) is a rare paediatric renal neoplasm. It is a diagnostic challenge to the pathologists due to its close differentials having ominous prognosis. We present three cases of CMN with unusual morphology including evidence of renal dysplasia in one of them. ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-008-2279-5
更新日期:2009-01-01 00:00:00
abstract::We have reviewed 233 patients with posterior urethral valves treated in a single center in Calcutta, India, over the last 20 years: 37 were neonates, 75 were between 1 and 12 months, 88 were between 1 and 5 years, and 33 were more than 5 years old when first seen. The clinical presentation and methods employed in diag...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830000495
更新日期:2001-01-01 00:00:00
abstract::Pulmonary sequestrations are non-functional masses of lung tissue lacking normal communication with the tracheobronchial tree and systemic-circulation-derived blood supply. The disconnection between the normal airway and pulmonary arterial supply prevents pulmonary sequestrations from participating in respiration whil...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-017-4072-9
更新日期:2017-07-01 00:00:00
abstract::With advances in neonatology, there is an increasing need for central vascular access in extremely small (<1,000 g) premature infants. Although the use of peripherally inserted central venous lines have become common practice, surgeons still frequently perform central venous line placements via cut-down in difficult a...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-005-1474-x
更新日期:2005-09-01 00:00:00
abstract:PURPOSE:Pediatric genitalia injury represents 0.6% of all pediatric trauma. It is crucial for providers to understand whether pediatric patients are at risk for violent mechanisms, such as rape, assault, or other abuse. Therefore, we sought to perform a large database analysis of pediatric and adolescent female genital...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-020-04736-7
更新日期:2020-10-01 00:00:00
abstract::Anorectal injuries (ARI) are uncommon in children in civil practice. In developed countries the injuries are mainly due to sexual abuse and firearms. This report reviews the experience in tropical Africa. A retrospective study of children aged 12 years or less managed for ARI over 10 years was undertaken. There were s...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830000347
更新日期:2000-01-01 00:00:00
abstract::Macrophages (MPs) produce increased levels of proinflammatory cytokines in Crohn's disease; these cytokines are thought to play a central role in the occurrence of the disease. Biologics are currently available for anti-cytokine therapy, but treating intestinal inflammation through direct suppression of proinflammator...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-006-1767-8
更新日期:2006-11-01 00:00:00
abstract:PURPOSE:Laparoscopic-assisted anorectoplasty (LAARP) is a minimally invasive procedure in which the levator ani muscle is left to potentially improve postoperative fecal continence. This study aimed to retrospectively evaluate postoperative complications and long-term outcomes of fecal continence after LAARP and compar...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-018-4323-4
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:There are many advantages of a SMOF emulsion (SMOF-lipid), such as liver-protective properties and anti-inflammatory effects. The objective of this study was to compare the clinical outcomes of SMOF-lipid with medium-chain triglycerides (MCT) /long-chain triglycerides (LCT) in infants after intestinal surger...
journal_title:Pediatric surgery international
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00383-018-4422-2
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:The role of thymectomy in the treatment of juvenile myasthenia gravis (JMG) is poorly defined. The objective of this systematic review was to evaluate the effect of thymectomy on survival, disease severity, and peri-operative complications for patients with JMG. METHODS:A search of MEDLINE, EMBASE, and the ...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-017-4086-3
更新日期:2017-06-01 00:00:00
abstract::The transverse colon is an exceptional location of intestinal duplication. Perforated duplications are rarely described in neonates. Meconium peritonitis (MP) can originate from prenatal perforated intestinal duplication. The authors report a case of a baby girl with prenatal diagnosis of MP. Rapid worsening of clinic...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-004-1349-6
更新日期:2005-02-01 00:00:00
abstract::The issues of sexual function and fertility are becoming relevant in patients with posterior urethral valves (PUV), as more of them reach adulthood. To evaluate the semen of post-pubertal patients with PUV as a determinant of future fertility, all such patients (age >16 years) attending the follow-up urology clinic of...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830100679
更新日期:2002-03-01 00:00:00
abstract:OBJECTIVES:Both aquaporin (AQP) 1 and the stem-cell factor/C-kit system seem to have a definite role in testis function, but very few studies have been reported in humans, especially in the paediatric age group. With the present study we wanted to investigate the expression of these proteins to better delineate their r...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-003-1125-z
更新日期:2004-04-01 00:00:00
abstract:AIM:In chick embryos, administration of cadmium (Cd) induces ventral body wall defects (VBWD) similar to human omphalocele. It has been shown that failure of proper VBW formation may be due to disruption of somite development during early embryogenesis. In the VBWD chick model, Cd causes abnormal cell death in the somi...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-012-3202-7
更新日期:2013-01-01 00:00:00
abstract::Primary hydatid disease of the pancreas is rare. The authors report a 3-year-old girl who had a cystic mass in the head of the pancreas with no other viscera involved. At laparatomy the entire endocyst was totally extracted from the surrounding pancreatic parenchyma. The postoperative course was uneventful. She is cur...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050677
更新日期:1999-01-01 00:00:00
abstract::A neonate with gastroschisis had silo placement and near-infrared spectroscopy (NIRS) monitoring of intestinal haemoglobin oxygen saturation (RSO2). An ischemic loop of bowel demonstrated decreased RSO2, with reversal of clinical ischemia and RSO2 postoperatively. This demonstrates possible advantage of monitoring int...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-014-3591-x
更新日期:2014-11-01 00:00:00
abstract::The interstitial cells of Cajal (ICC) play an important role in the control of gut motility. The recognition that the ICC cell membrane harbors the c-kit receptor (CD117) sparked rapid advancement in ICC research on the gut and certain pathologies using immunochemical and molecular methods. The question arises whether...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-004-1314-4
更新日期:2005-03-01 00:00:00
abstract::Modern plastic and reconstructive surgery continues to significantly improve the functional and aesthetic post-burn sequelae in children. It has become a major factor in restoring mobility, aesthetic appearance, self-esteem, and quality of life. The entire spectrum of plastic reconstructive procedures should be availa...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/BF01076930
更新日期:1997-07-01 00:00:00
abstract::Diagnostic evaluation and treatment of blunt liver trauma in children have changed essentially over the last decades. In the period between January 1975 and December 2002, a total of 45 children, 18 girls and 27 boys, between the ages of 1 and 16 years (mean 8.19) were treated for liver rupture following blunt abdomin...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-004-1276-6
更新日期:2004-12-01 00:00:00
abstract::Juvenile papillomatosis (JP) is a rare benign, proliferative breast tumor in children. We observed a 9-year-old girl with a large soft-tissue mass at the lower outer quadrant of the left breast. Ultrasonography showed an ill-defined, inhomogeneous mass with numerous small, hypoechoic areas. The tumor was completely ex...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830000462
更新日期:2001-03-01 00:00:00
abstract::Fetal skin wounds heal scarlessly while adult wounds scar. Fetal wound healing occurs in a physiologically hypoxic environment whereas in adult wound healing, cells have to acutely adapt to hypoxia caused by locally impaired blood supply. We examined the expression of hypoxia-inducible factor 1 (HIF-1), a potent trans...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050735
更新日期:2000-01-01 00:00:00
abstract:PURPOSE:The loss of normal anatomic barriers in neonates with congenital diaphragmatic hernia (CDH) can predispose children to gastroesophageal reflux (GER). In an attempt to improve post-operative feeding, we have added a modified anterior fundoplication to restore natural gastric and esophageal positioning. METHODS:...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-009-2411-1
更新日期:2009-08-01 00:00:00
abstract:PURPOSE:Since DX/HA was approved by the Food and Drug Administration in 2001 as an acceptable tissue-augmenting substance for subureteral injection, endoscopic treatment has become increasingly popular for treating vesicoureteral reflux (VUR). However, most paediatric urologists still continue to recommend ureteral rei...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-010-2650-1
更新日期:2010-10-01 00:00:00