Abstract:
:At bilateral orchiopexy bilateral biopsies may be indicated to determine fertility potential. It is currently unknown if the serum inhibin B levels at time of orchiopexy reflect the testicular status of the bilaterally cryptorchid child. The aim of this study was to relate the results of inhibin B and FSH measurements with testicular biopsy parameters in bilateral cryptorchid boys. Included were 25 boys with bilateral cryptorchidism, median 2.5 years (9 months to 5.5 years) at surgery for bilateral cryptorchidism with simultaneous testicular biopsies, and blood sample for inhibin B and FSH. The number of spermatogonia and gonocytes was measured in 100 tubular transverse sections, the S/T and the mean-S/T of the patient was found, and expressed as percent of lowest normal value. Inhibin B and FSH were measured and related to age-specific values. Forty percent (10/25) of the patients had very low mean-S/T (mean-S/T<10% of lowest normal-value). Inhibin B was decreased in 24% (6/25) of the patients, all with decreased mean-S/T, predominantly with a mean-S/T<10% of lowest normal-value (p<0.05). There was a negative correlation between inhibin B and FSH (p<0.05). In cases of mean-S/T<10% of lowest normal-value and decreased inhibin B, we found increased FSH in 9% (2/22) of the patients and hypergonadotropic hypogonadism was suspected. Low FSH was found in 5% (1/22) of the patients and hypogonadotropic hypogonadism was suspected. Low inhibin B predicts a serious condition in respect of infertility. Low FSH and inhibin B indicates examination for hypogonadotropic hypogonadism. In bilateral cryptorchid boys inhibin B levels correlated negatively to FSH.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Cortes D,Thorup J,Hogdall E,Norgaard-Pedersen B,Petersen BL,Hogdall Cdoi
10.1007/s00383-006-1839-9subject
Has Abstractpub_date
2007-02-01 00:00:00pages
163-9issue
2eissn
0179-0358issn
1437-9813journal_volume
23pub_type
杂志文章abstract::Colonic interposition is a treatment option in childhood when esophageal replacement (ER) is necessary. We reviewed 18 children who underwent ER by colon between 1984 and 1999. There were 5 with esophageal atresia and 13 with corrosive esophagitis; 15 had long-term follow-up (mean 38 months). Three procedures were per...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830000422
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVES:Both aquaporin (AQP) 1 and the stem-cell factor/C-kit system seem to have a definite role in testis function, but very few studies have been reported in humans, especially in the paediatric age group. With the present study we wanted to investigate the expression of these proteins to better delineate their r...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-003-1125-z
更新日期:2004-04-01 00:00:00
abstract::In many very-low-birth-weight (VLBW) infants the ductus arteriosus fails to close spontaneously, and they subsequently develop signs and symptoms of poor tissue perfusion and heart failure. This study evalutes the results of early surgical closure of patent ductus arteriosus (PDA). We retrospectively reviewed the reco...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830000515
更新日期:2001-07-01 00:00:00
abstract::A case of extrahepatic biliary atresia (EBA) associated with trisomy 18 is presented. A 1-month-old boy was suspected to have Alagille syndrome with obstructive jaundice, a systolic heart murmur, growth retardation, and a small, pointed chin. However, surgery and chromosomal analysis revealed EBA associated with triso...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050536
更新日期:1999-01-01 00:00:00
abstract:PURPOSE:To study the gender assignment and hormonal treatment advocated for disorders of sexual differentiation (DSD). METHODS:A study was done on patients who were reviewed in the Pediatric Intersex Clinic to evaluate the pattern of gender assignment and hormonal treatment advocated. RESULTS AND CONCLUSION:The patie...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-008-2232-7
更新日期:2008-10-01 00:00:00
abstract:AIM:The Ncx/Hox11L.1 gene is required for adequate development of enteric neurons in mice and Ncx/Hox11L.1 deficient (Ncx-/-) mice are used as a model for human intestinal neuronal dysplasia (IND) because of similar histopathology (hyperganglionosis), however, some 50% of Ncx-/- mice develop megacolon with a caliber ch...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-009-2451-6
更新日期:2009-11-01 00:00:00
abstract:PURPOSE:The purpose of this study was to review the clinical characteristics and prognosis of children with adrenocortical tumors (ACT). METHODS:We retrospectively reviewed the medical records of 28 patients with ACT at our hospital between March 2010 and March 2017. RESULTS:The main clinical presentations were sexua...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-018-4409-z
更新日期:2019-03-01 00:00:00
abstract:INTRODUCTION:Objectively evaluating the lack of bowel control (fecal incontinence) continues to be a challenge. Many have attempted to measure the severity of fecal incontinence and to evaluate its impact on the quality of life by developing standardized scoring systems. Some of these systems have been validated but no...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-016-3909-y
更新日期:2016-08-01 00:00:00
abstract::To evaluate the efficacy of ultrasound (US) guided percutaneous sclerotherapy in the pediatric population, 14 hydatid liver cysts (HLC) in eight male patients whose ages ranged between 6 and 16 years (mean 9.9 years) were treated. The maximum diameter was 110 mm. Albendazole was administered orally to all patients for...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830000356
更新日期:2000-01-01 00:00:00
abstract::Numerous case reports in the literature have suggested a causal link between beta-haemolytic streptococcal infection and delayed-onset right-sided diaphragmatic hernia/eventration in the perinatal age group. We report a child with antenatally documented right diaphragmatic eventration 4 weeks before birth who subseque...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:
更新日期:1997-03-21 00:00:00
abstract::Surgical extirpation is the treatment of choice for symptomatic mullerian duct remnants (prostatic utricle, PU), and several surgical approaches have been described for the treatment of this pathology. A group of 11 patients with symptomatic PU were observed and treated. Associated anomalies included proximal or penos...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:
更新日期:1997-03-21 00:00:00
abstract:UNLABELLED:Necrotizing enterocolitis (NEC) is a serious condition with a high morbidity and mortality commonly affecting premature babies. Data for the impact of the long-term disease burden in developing countries are limited although poor long-term outcome of surgically managed patients has been shown in terms of inc...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-010-2583-8
更新日期:2010-04-01 00:00:00
abstract:PURPOSE:Voltage-gated potassium ion channels have long been implicated in gastrointestinal motility. Recent studies have highlighted the role of voltage-gated channel subfamily G member 3 (KCNG3) and 4 (KCNG4) genes in the electrical functioning of interstitial cells of Cajal and PDGFRα+ cells of the mouse colon. We de...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-018-4394-2
更新日期:2019-02-01 00:00:00
abstract::Recently, laparoscopic orchidopexy has been accepted as the standard procedure of management for clinically impalpable testes. However, many techniques have been described for the delivery of the mobilized testes. In this report, a new approach is described. The use of a fourth "scroto-peritoneal" port, makes complete...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050372
更新日期:1998-07-01 00:00:00
abstract:PURPOSE:Laparoscopic-assisted anorectoplasty (LAARP) is considered to benefit the patients with vesico-prostatic fistula. The aim of this study is to present the details of our LAARP technique for improving the short- and long-term outcomes in the patients with high and intermediate types of anorectal malformations (AR...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-019-04614-x
更新日期:2020-03-01 00:00:00
abstract::Accidental ingestion of corrosive substances remains a major health hazard in children. Most infants and children who ingest caustic substances present with very few symptoms or signs. Approximately 40% of caustic substance ingestions result in esophageal injury, but the optimal management of caustic esophageal burns ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-004-1331-3
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND:Preoperative factors have been correlated with pre-incision hypotension (PIH) in children undergoing surgery, suggesting that PIH can be predicted through preoperative screening. We studied blood pressure (BP) changes in the 12 min following the induction of anesthesia to study the incidence of post-inductio...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-018-4359-5
更新日期:2018-12-01 00:00:00
abstract::The successful use of a combination of "patch, drain, and wait" (PDW) and home total parenteral nutrition (TPN) in the management of a case of acute, catastrophic midgut volvulus in a 2-year-11-month-old boy with near-total ischemia/necrosis of his small intestine is reported. The PDW approach to the highly effective ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:
更新日期:1997-03-21 00:00:00
abstract:BACKGROUND:Cervicovaginal atresia is a rare Mullerian anomaly. The management of cervicovaginal atresia has evolved from historical recommendations of hysterectomy to various reconstructive procedures more recently. The latter carries a risk of significant morbidity and unknown fertility. We present our experience in t...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-014-3550-6
更新日期:2014-10-01 00:00:00
abstract::Colostomy shift en masse is a novel technique in which the colostomy is shifted along with a rim of skin and abdominal wall tissue. This provides additional length of distal bowel if needed during pull-through anastomosis. We have treated three cases (two Hirschsprung's disease and one anorectal malformation) with col...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-003-1043-0
更新日期:2003-11-01 00:00:00
abstract::Gastroschisis closure is performed either primarily or after staged reduction of the prolapsed bowel. A technique for surgical closure of the abdominal wall defect is described which allows for an almost scarless appearance of the abdominal surface with preservation of a midline umbilicus. ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-008-2215-8
更新日期:2008-09-01 00:00:00
abstract::Traditionally, open repair of esophageal atresia (EA) with tracheoesophageal fistula (TEF) required thoracotomy. Innovations in minimal access surgery have created a thoracoscopic technique resulting in violation of the pleural space. Most pediatric surgeons favor an extrapleural approach for open repair. We present a...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-005-1366-0
更新日期:2005-04-01 00:00:00
abstract::Peri-catheter calcification is an unusual and previously unreported complication of central venous (CV) catheterization in infants. A 1. 9 Fr Silastic CV catheter was placed in a term infant for administration of total parenteral nutrition and antibiotics following intra-abdominal sepsis. The catheter was removed, wit...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050418
更新日期:1998-10-01 00:00:00
abstract::In the published version, the Acknowledgements section was missing a funding note of co-author Dr C Verrill. The corrected version should read as follows. ...
journal_title:Pediatric surgery international
pub_type: 已发布勘误
doi:10.1007/s00383-020-04624-0
更新日期:2020-04-01 00:00:00
abstract:AIM:Prepubertal testicular tumors are rare in children. We aim to present clinical and histological features of prepubertal testicular tumors through the analysis of the long-term experiences of a single medical center of China. MATERIALS AND METHODS:A total of 67 children (≤ 14 years) treated for testicular tumor at ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-018-4366-6
更新日期:2018-12-01 00:00:00
abstract::Pullthrough procedures for Hirschsprung diseases typically have favorable results. However, some children experience long-term postoperative complications comprising stooling disorders, such as intermittent enterocolitis, severe stool retention, intestinal obstruction, as well as incontinence. Reoperative Hirschsprung...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-016-4045-4
更新日期:2017-04-01 00:00:00
abstract::Parathyroid carcinoma is unusual and its intrathyroidal variant is extremely rare. Therefore, few cases have been reported to describe a case of parathyroid carcinoma located inside the thyroid gland. The case corresponds to a 14-year-old girl who came to the office with a severe osteoarticular disease, depression, ca...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-011-2904-6
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND/PURPOSE:To determine the frequency and characteristics of suspected cow's milk protein allergy (CMPA) in infants with gastroschisis and response to change in milk. METHODS:A retrospective cohort study of 111 consecutive infants with gastroschisis. RESULTS:64 episodes suggesting non-IgE-mediated CMPA occurr...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-015-3664-5
更新日期:2015-03-01 00:00:00
abstract:PURPOSE:Partial hepatectomy (PH) can be an inevitable surgical therapy in some conditions, such as hepatic malignancies, trauma or partial liver transplantation. Its capacity for regeneration distinguishes the liver from other essential organs. Regeneration is a complex process involving growth factors, cytokines, tran...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-009-2529-1
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVES:This study reviews the results of our previously described modification of the minimally invasive (Nuss) procedure for correction of pectus excavatum. It utilizes a subxyphoid incision with central fixation to maximize safe bar passage and minimize bar displacement. METHODS:Consecutive patients corrected wi...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-017-4195-z
更新日期:2018-01-01 00:00:00