Abstract:
OBJECTIVE:To assess the role of magnetic resonance imaging, specifically magnetic resonance spectroscopy (MRS) and susceptibility-weighted imaging (SWI), in the evaluation of children with traumatic brain injury (TBI). DATA SOURCES:Literature review and data from our recently published clinical studies. STUDY SELECTION:Children with pediatric TBI who underwent SWI. SWI is a 3-dimensional high-resolution magnetic resonance imaging technique that is more sensitive in detecting hemorrhagic lesions seen with diffuse axonal injury (DAI) than conventional imaging. MRS acquires metabolite information that reflects neuronal integrity and function from multiple brain regions and offers early prognostic information regarding outcome. DATA EXTRACTION:Literature review. DATA SYNTHESIS:Literature review and review of recently published data from our institution. CONCLUSIONS:The data suggest that more sensitive imaging techniques that provide early evidence of injury and that are better predictors of outcome are needed to identify children at risk for such deficits. Specifically, the number and volume of hemorrhagic DAI lesions as well as changes in spectral metabolites such as reduced N-acetylaspartate or elevations in choline-related compounds correlate with neurologic disability and impairments of global intelligence, memory, and attention.
journal_name
Arch Phys Med Rehabiljournal_title
Archives of physical medicine and rehabilitationauthors
Ashwal S,Babikian T,Gardner-Nichols J,Freier MC,Tong KA,Holshouser BAdoi
10.1016/j.apmr.2006.07.275subject
Has Abstractpub_date
2006-12-01 00:00:00pages
S50-8issue
12 Suppl 2eissn
0003-9993issn
1532-821Xpii
S0003-9993(06)01280-9journal_volume
87pub_type
杂志文章,评审abstract:OBJECTIVE:To describe group therapy utilization in spinal cord injury (SCI) inpatient rehabilitation. DESIGN:Prospective observational study. SETTING:Six inpatient rehabilitation facilities. PARTICIPANTS:Patients (N=1376) receiving initial rehabilitation after traumatic SCI. INTERVENTIONS:Not applicable. MAIN OUTC...
journal_title:Archives of physical medicine and rehabilitation
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更新日期:2013-04-01 00:00:00
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journal_title:Archives of physical medicine and rehabilitation
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journal_title:Archives of physical medicine and rehabilitation
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journal_title:Archives of physical medicine and rehabilitation
pub_type: 临床试验,杂志文章
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journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章,多中心研究
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更新日期:2010-09-01 00:00:00
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更新日期:2010-02-01 00:00:00
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journal_title:Archives of physical medicine and rehabilitation
pub_type: 临床试验,杂志文章
doi:
更新日期:1982-05-01 00:00:00
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更新日期:2006-04-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2014-05-01 00:00:00
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journal_title:Archives of physical medicine and rehabilitation
pub_type: 临床试验,杂志文章
doi:
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pub_type: 杂志文章
doi:
更新日期:1990-03-01 00:00:00
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doi:
更新日期:1984-09-01 00:00:00
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doi:
更新日期:1987-02-01 00:00:00
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journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
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更新日期:2011-04-01 00:00:00
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更新日期:2004-07-01 00:00:00
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更新日期:2010-03-01 00:00:00
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更新日期:2010-04-01 00:00:00
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更新日期:1983-03-01 00:00:00
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更新日期:2016-03-01 00:00:00
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更新日期:2021-01-13 00:00:00
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更新日期:2017-10-01 00:00:00
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更新日期:2012-11-01 00:00:00
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更新日期:2013-03-01 00:00:00
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更新日期:2010-10-01 00:00:00
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journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
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更新日期:2009-02-01 00:00:00
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journal_title:Archives of physical medicine and rehabilitation
pub_type: 杂志文章
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更新日期:1998-06-01 00:00:00