Postradiation sarcoma of the chest wall: report of two cases.

Abstract:

:Postradiation sarcoma is a rare late complication of external radiotherapy. We herein present two cases with this disease. A 54-year-old man had undergone a lobectomy and chest wall resection for Pancoast type lung cancer 7 years previously. He had undergone irradiation with a total dose of 50 Gy. Computed tomography (CT) demonstrated a tumorous expansion of the right lateral thoracic wall. A pathological examination confirmed a diagnosis of osteosarcoma. A 60-year-old woman had undergone a resection of the lateral chest wall mass, which was diagnosed to be Hodgkin's disease in 1991. Chemotherapy was given postoperatively. A tumorous lesion arose again and irradiation was performed with a total dose of 110 Gy. In 2000, two tumors appeared in the irradiation field. A pathological examination showed a sarcoma with divergent differentiation. In 2003, a tumor recurred and was diagnosed to be a liposarcoma. Patients who have received radiotherapy should therefore be followed up while taking into consideration the possible development of postradiation sarcoma.

journal_name

Surg Today

journal_title

Surgery today

authors

Ninomiya H,Miyoshi T,Shirakusa T,Shiraishi T,Yamamoto N,Nabeshima K

doi

10.1007/s00595-004-3300-9

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

1101-4

issue

12

eissn

0941-1291

issn

1436-2813

journal_volume

36

pub_type

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