Abstract:
:Postradiation sarcoma is a rare late complication of external radiotherapy. We herein present two cases with this disease. A 54-year-old man had undergone a lobectomy and chest wall resection for Pancoast type lung cancer 7 years previously. He had undergone irradiation with a total dose of 50 Gy. Computed tomography (CT) demonstrated a tumorous expansion of the right lateral thoracic wall. A pathological examination confirmed a diagnosis of osteosarcoma. A 60-year-old woman had undergone a resection of the lateral chest wall mass, which was diagnosed to be Hodgkin's disease in 1991. Chemotherapy was given postoperatively. A tumorous lesion arose again and irradiation was performed with a total dose of 110 Gy. In 2000, two tumors appeared in the irradiation field. A pathological examination showed a sarcoma with divergent differentiation. In 2003, a tumor recurred and was diagnosed to be a liposarcoma. Patients who have received radiotherapy should therefore be followed up while taking into consideration the possible development of postradiation sarcoma.
journal_name
Surg Todayjournal_title
Surgery todayauthors
Ninomiya H,Miyoshi T,Shirakusa T,Shiraishi T,Yamamoto N,Nabeshima Kdoi
10.1007/s00595-004-3300-9subject
Has Abstractpub_date
2006-01-01 00:00:00pages
1101-4issue
12eissn
0941-1291issn
1436-2813journal_volume
36pub_type
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