Abstract:
:In spite of reports on cytokines induction by the Brucella DNA in murine model, there is no comparison between pathogenic and appropriate vaccine strains in human. We investigated the cytokines profile of human peripheral blood mononuclear cells (PBMCs) induced by DNA extracted from pathogenic isolates of Brucella melitensis and B. abortus as well as Rev1 and S19; the appropriate vaccine strains. It was observed that despite differential induction of Interleukin(IL)-12 and IL-10 production, identical IL-12/IL-10 concentration ratio was obtained by all Brucella strains DNAs that was 2 after 24 h and 4 after 5 days of incubation. In addition, IL-2 and Interferon(IFN)-gamma production were profoundly increased compared to the medium at day 3 and 5 respectively but IFN-alpha was not induced. Therefore, Brucella strains DNAs are Th1 inducing component with similar pattern in human PBMCs.
journal_name
Microbiol Resjournal_title
Microbiological researchauthors
Lashkarbolouki T,Ardestani SK,Kariminia A,Ziaee AA,Torkabadi E,Ebrahimi Mdoi
10.1016/j.micres.2006.07.012subject
Has Abstractpub_date
2008-01-01 00:00:00pages
466-72issue
4eissn
0944-5013issn
1618-0623pii
S0944-5013(06)00092-9journal_volume
163pub_type
杂志文章abstract::In a laboratory incubation study, methane (CH4) production in two saline soils and a nonsaline soil sample was investigated under flooded conditions. Mean CH4 production was remarkable (630.86 ng CH4/g) in nonsaline alluvial soil, but low (12.97 ng CH4/g) in acid sulfate saline (Pokkali) soil which was attributed to t...
journal_title:Microbiological research
pub_type: 杂志文章
doi:10.1016/S0944-5013(00)80035-X
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journal_title:Microbiological research
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journal_title:Microbiological research
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journal_title:Microbiological research
pub_type: 杂志文章
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journal_title:Microbiological research
pub_type: 杂志文章
doi:10.1078/0944-5013-00078
更新日期:2001-01-01 00:00:00
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journal_title:Microbiological research
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journal_title:Microbiological research
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doi:10.1016/j.micres.2004.07.002
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journal_title:Microbiological research
pub_type: 杂志文章
doi:10.1016/j.micres.2016.09.005
更新日期:2016-12-01 00:00:00
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journal_title:Microbiological research
pub_type: 杂志文章
doi:10.1016/S0944-5013(96)80026-7
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journal_title:Microbiological research
pub_type: 杂志文章
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journal_title:Microbiological research
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journal_title:Microbiological research
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abstract::The community and Cd-resistance of endophytic fungi from roots of Salix variegata Franch. collected from the water-level-fluctuation zone of Three Gorges Reservoir Region, China, were investigated. A total of 53 strains were isolated and identified to 13 morphotaxa, in which Chromosporium, Fusarium and Gonatobotrys we...
journal_title:Microbiological research
pub_type: 杂志文章
doi:10.1016/j.micres.2015.03.013
更新日期:2015-07-01 00:00:00
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journal_title:Microbiological research
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doi:10.1016/j.micres.2014.08.008
更新日期:2015-01-01 00:00:00
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journal_title:Microbiological research
pub_type: 杂志文章
doi:10.1016/S0944-5013(11)80052-2
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abstract::Salmonella enterica serovar Enteritidis (S. Enteritidis, SE) is a major cause of foodborne diseases for humans. The completeness of the O-chain antigen of Lipopolysaccharide (LPS) determines whether a S. Enteritidis strain is smooth or rough. However, genes that are involved in the synthesis of LPS and rough-smooth va...
journal_title:Microbiological research
pub_type: 杂志文章
doi:10.1016/j.micres.2018.05.001
更新日期:2018-01-01 00:00:00
abstract::For a long a time programmed cell death was thought to be a unique characteristic of higher eukaryotes, but evidence has accumulated showing that programmed cell death is a universal phenomenon in all life forms. Many different types of bacterial programmed cell death systems have been identified, rivalling the eukary...
journal_title:Microbiological research
pub_type: 杂志文章,评审
doi:10.1016/j.micres.2017.11.016
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