Influence of breast cancer margin assessment method on the rates of positive margins and residual carcinoma.

Abstract:

BACKGROUND:We hypothesized that the method of breast cancer margin assessment may be associated with different rates of positive margins and residual carcinoma. METHODS:A total of 178 breast cancer specimens were divided into 2 groups (A and B) based on the margin assessment method used. Rates of positive margins, re-excision, and residual carcinoma at re-excision were compared and analyzed statistically. RESULTS:At least 1 margin was positive in 64.7% in group A and in 65.2% in group B. At directed re-excision 54% in group A and 51% in group B had residual carcinoma. The lateral margin was positive in 44% in group A compared with 26% in group B (P = .06). The posterior margin was positive in 19% in group A and in 51% in group B (P = .001). CONCLUSIONS:Two different breast cancer specimen margin assessment methods had comparable rates of positive margins and residual carcinoma at re-excision. Different patterns of specific margin positivity suggest that the method of margin assessment may alter results.

journal_name

Am J Surg

authors

Méndez JE,Lamorte WW,de Las Morenas A,Cerda S,Pistey R,King T,Kavanah M,Hirsch E,Stone MD

doi

10.1016/j.amjsurg.2006.06.009

subject

Has Abstract

pub_date

2006-10-01 00:00:00

pages

538-40

issue

4

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(06)00443-0

journal_volume

192

pub_type

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