Pancreaticoduodenectomy for nonperiampullary primary tumors.

Abstract:

INTRODUCTION:This review was performed to evaluate the outcome of patients undergoing pancreaticoduodenectomy (PD) for isolated metastatic or locally advanced nonperiampullary tumors at a single institution over a 13-year period. METHODS:Between 1983 and 1996, patients undergoing PD for metastatic or locally advanced nonperiampullary malignancies were identified. Medical records were reviewed and outcome factors and survival data analyzed. RESULTS:Eighteen patients were identified. The primary tumor histopathology included colon (n = 7), gastric (n = 4), renal cell (n = 3), lung (n = 2), bladder (n = 1), and melanoma (n = 1). The median length of hospital stay was 15 days (6 to 48) with one perioperative death (5.5%). The median tumor size was 5.5 cm (0.8 to 11.5), and 7 patients had positive peripancreatic lymph nodes. The median survival was 40 months, with a 5-year survival of 35%. CONCLUSIONS:Pancreaticoduodenectomy for nonperiampullary malignancy is infrequently indicated. However, in the absence of widely metastatic disease, PD should be considered for locally advanced tumors or isolated metastatic malignancy.

journal_name

Am J Surg

authors

Harrison LE,Merchant N,Cohen AM,Brennan MF

doi

10.1016/s0002-9610(97)00121-9

subject

Has Abstract

pub_date

1997-10-01 00:00:00

pages

393-5

issue

4

eissn

0002-9610

issn

1879-1883

pii

S0002961097001219

journal_volume

174

pub_type

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