Abstract:
BACKGROUND:The relationship between morbid obesity (MO) and insulin resistance (IR) has been widely demonstrated. The euglycemic-hyperglycemic clamp method for diagnosis of IR is neither practical nor cost-effective for population-based studies. However, the application of mathematical models (HOMA, QUICKI and Mf(fm) indices) can be useful. METHODS:The data from 171 patients were retrospectively evaluated. We recorded general anthropometric parameters and the basal levels of glucose, triglycerides and insulin and calculated the metabolic indexes both before surgery (Capella gastric bypass) and 6, 12, 24, 36 and 48 months after the operation. RESULTS:Before surgery, patients could be classified according to their waist-hip ratio (WHR) into 2 groups. Group A (n = 131, 108 females and 23 males) with WHR values 1.10 +/- 0.1 SD for males and 0.94 +/- 0.1 for females (central obesity); and Group B (n = 40, 34 females and 6 males) with WHR values 0.90 +/- 0.1 for males and 0.84 +/- 0.1 for females (peripheral obesity). Group A patients showed elevated serum levels of glucose, triglycerides and insulin and high values of the HOMA index with low values of QUICKI and Mf(fm). Group B patients showed lower levels of glucose, triglycerides, insulin and HOMA index and higher values of QUICKI and Mf(fm). These abnormal levels began to decrease 6 months after bypass and the QUICKI and Mf(fm) began to increase. CONCLUSIONS:The high baseline levels of insulin and the high prevalence of hypertension, diabetes or both conditions in patients with central obesity confirm that they suffer a metabolic syndrome, Meanwhile, patients with peripheral obesity with lower levels of chemical parameters and of the metabolic indices suffer peripheral resistance against insulin. Clinical application of these mathematical indices can be useful in patients with MO; they are easily performed and lack the high costs and risks associated with the clamp technique.
journal_name
Obes Surgjournal_title
Obesity surgeryauthors
Ruano M,Silvestre V,Castro R,García-Lescún MC,Aguirregoicoa E,Marco A,Rodríguez A,García-Blanch Gdoi
10.1381/096089206776945048subject
Has Abstractpub_date
2006-05-01 00:00:00pages
549-53issue
5eissn
0960-8923issn
1708-0428journal_volume
16pub_type
杂志文章相关文献
OBESITY SURGERY文献大全abstract:BACKGROUND:Bariatric surgery is the most effective treatment for morbid obesity and associated medical co morbidities. There is currently minimal surgical treatment penetration of this widespread disease. BLIS has been able to improve the access to bariatric surgery for cash-pay patients by alleviating concern about th...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-012-0745-6
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:It is unclear whether specific gut microbiota is associated with remission of type 2 diabetes (T2D) after distinct types of bariatric surgery. AIMS:The aim of this study is to examine gut microbiota changes after laparoscopic Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG) surgery in obese patien...
journal_title:Obesity surgery
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11695-016-2399-2
更新日期:2017-04-01 00:00:00
abstract:AIM:Our primary aim was to determine whether non-attendance at pre-operative clinics were associated with non-attendance at post-operative clinics and its influence on weight loss. We also sought to examine the relationship between gender, ethnicity and post-operative clinic attendance with respect to weight loss post-...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-019-03843-2
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Long-term effects of bariatric surgery in morbidly obese type 1 patients are unknown. Five to eight-year experience in the case series of type 1 diabetes subjects is presented. METHODS:Three poorly controlled type 1 diabetes patients, aged 19, 23, and 28 underwent Roux-en-Y gastric bypass surgery. RESULTS:...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-010-0074-6
更新日期:2010-04-01 00:00:00
abstract::Gastric leak after sleeve gastrectomy can lead to significant morbidity and mortality. The aim of this study was to examine the safety and efficacy of endoscopic deployment of a covered esophageal stent in the management of leaks after sleeve gastrectomy. Three consecutive patients who underwent sleeve gastrectomy at ...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-010-0186-z
更新日期:2010-09-01 00:00:00
abstract:UNLABELLED:Laparoscopic gastric banding and Roux-en-Y gastric bypass are widely used for the treatment of morbid obesity. The impact of these two procedures on health-related quality of life has not been analyzed in comparative studies. METHODS:A matched-pair analysis of a prospectively collected database was performe...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-008-9522-y
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:Gastric banding is a safe and efficient bariatric procedure. We report here the results of 591 consecutive gastric bandings in terms of excess weight loss with up to 10 years follow-up and the complications. METHODS:Between June 1996 and September 2006, 591 patients underwent laparoscopic adjustable gastric...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-008-9470-6
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:This study evaluated early and medium-term changes in bone turnover markers, and their associations with weight loss, total bone mineral density (BMD), and hormonal changes after biliopancreatic diversion (BPD). METHODS:Ancillary study from a one-year prospective cohort of 16 individuals assessed before, 3 ...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-018-3617-x
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Laparoscopic adjustable gastric banding is a safe and effective treatment method for morbid obesity. Injection port dislocation, tube perforation and access port infection are generally classified among the minor complications, although they can require a reoperation at the port-site or even at the level of ...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/096089202762552791
更新日期:2002-04-01 00:00:00
abstract::The sleeve gastrectomy (SG) is the most popular weight loss procedure in the USA. Despite its popularity, little is definitively known about the variables that correlate with weight loss. We performed a literature search to find studies that reported variables that correlated with weight loss following SG. Forty-eight...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-018-03666-7
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Research about personality factors involved in successful outcome after bariatric surgery has led to contrasting results. The reasons for such discrepancies may include the lack of assessment of adaptive personality traits and of psychiatric co-morbidity, which may limit the reliability of personality findin...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/096089206777822278
更新日期:2006-07-01 00:00:00
abstract::Two morbidly obese patients are presented. The first patient is a 38-year-old superobese female with BMI 56.2 in a wheelchair secondary to multiple sclerosis. The second patient is a 49-year-old female with BMI 47.7 confined to a wheelchair secondary to spinal cord transection due to a motor vehicle accident. Both pat...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-008-9466-2
更新日期:2008-12-01 00:00:00
abstract::The relevance of a post-gastroplasty physician-and dietitian-supervised support group for weight loss, dietary habits, dietary knowledge, and exercise has been assessed. Two post vertical banded gastroplasty groups were compared: those who did (n = 10) and those who did not (n = 11) attend a monthly post-gastroplasty ...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/096089293765559070
更新日期:1993-11-01 00:00:00
abstract:PURPOSE:Growing evidence in the literature suggests that obesity is capable of altering reproductive hormone levels and male fertility. Effects on classic semen parameters and sperm DNA fragmentation (SDF), however, have not been properly established. Additionally, the impact of bariatric surgery (BS) on those paramete...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-020-04851-3
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:In bariatric surgery patients, weight loss and long-term weight maintenance are related to food intake and eating patterns. To improve the diet orientation in the bariatric surgery postoperative period, we assessed the postoperative eating patterns and related them to weight loss. METHODS:This was a transve...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-008-9704-7
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:Bariatric surgery is performed mostly on obese women of reproductive age. Many studies have analyzed pregnancy outcomes after bariatric surgery, but only a small number have studied the impact of pregnancy on the postoperative outcomes. PURPOSE:To study the effect of pregnancy on outcomes after bariatric su...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-020-04643-9
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Variations have been proposed in order to improve weight loss and decrease complication profiles in Roux-en-Y gastric bypass (RYGB) patients. We previously reported a preliminary result of pericardial patch ring RYGB. We aim to report a detailed result of banded RYGB by comparing these patients to non-banded...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-017-2832-1
更新日期:2018-01-01 00:00:00
abstract::End-stage renal failure is most commonly caused by the obesity-related diseases, diabetes mellitus and essential hypertension, and is best treated with renal transplantation. Obesity may contribute to poor patient and graft survival, and is an exclusion criterion in some renal transplant programs. Diet and exercise pr...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/0960892053723349
更新日期:2005-04-01 00:00:00
abstract::A peculiar category of persons with obesity lacking common metabolic disturbances has been depicted and termed as metabolically healthy obesity (MHO). Yet, although MHO patients are free of obesity-associated complications, they might not be entirely precluded from developing cardio-metabolic disorders. Among patients...
journal_title:Obesity surgery
pub_type: 杂志文章,评审
doi:10.1007/s11695-019-03964-8
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are performed in patients with obesity and type 2 diabetes mellitus (T2DM). The aim of this study is to evaluate retrospectively the clinical efficacy of RYGB and SG in two groups of obese T2DM patients. METHODS:From the hospital database, we extra...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-012-0657-5
更新日期:2012-10-01 00:00:00
abstract::Severe thiamine (vitamin B-1) deficiency is a medical emergency that has long been recognized as a potential complication of bariatric surgery. The incidence of this rare complication is largely unknown. We describe a super-obese male patient with extreme lower limb weakness 3 months following a duodenal switch operat...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-008-9539-2
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:Lapaparoscopic adjustable gastric banding (LAGB) has become a widespread method to treat morbid obesity. Long-term complications and failures require a strategy for reoperation. METHODS:1,180 patients have been operated on from April 1995 to December 2003. 151 had reoperation for complications (12.7%) exclu...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/0960892041719545
更新日期:2004-08-01 00:00:00
abstract:BACKGROUND:The technical aspects of access-port (AP) placement are not generally described in Lap-Band series. METHODS:From November 2000 to April 2002, we performed Lap-Band procedures laparoscopically on 180 patients. A retrospective review was conducted of 3 consecutive AP-placement techniques in nonselected and de...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/096089203322618759
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND:The study aim was to determine the prevalence of abnormal serum biochemistries associated with micronutrient deficiencies before and after laparoscopic sleeve gastrectomy (LSG). METHODS:Two hundred and one patients had LSG surgery between May 2011 and May 2014. Using a prospective cohort study design, data ...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-017-3007-9
更新日期:2018-08-01 00:00:00
abstract::The prevalence of morbid obesity has been increasing worldwide. Therefore, multiple laparoscopic adjustable gastric bandings (LAGBs) have been placed in Belgium in the nineties. The procedure was considered as minimal invasive with low morbidity rates. However, some publication cases suggest a possible association bet...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-019-03708-8
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Obesity has become a global epidemic. Surgical treatment of obesity and metabolic disorders in China is increasing rapidly, but it is still a new discipline even to health professionals. As an important member of the multidisciplinary team, the knowledge and attitudes of nurses provide crucial health care to...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-019-04173-z
更新日期:2020-02-01 00:00:00
abstract::The ability to obtain accurate histories for a comparative study of compulsive overeating and alcoholism was severely compromised by the high degree of denial, shame and self-blame present in these two overlapping disease entities. Areas of overlap included similar progression of the disease, familial tendencies, and ...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/096089293765559827
更新日期:1993-02-01 00:00:00
abstract::One of the roles of the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) is to provide guidance on the management of patients seeking surgery for adiposity-based chronic diseases. The role of endoscopy around the time of endoscopy is an area of clinical controversy. In 2018, IFSO comm...
journal_title:Obesity surgery
pub_type: 杂志文章,评审
doi:10.1007/s11695-020-04720-z
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:The continuing need for simple, safe, and effective procedures led us to design a new operation for treating morbid obesity. METHODS:Thirty-two patients underwent our novel procedure, sleeve gastrectomy plus side-to-side jejunoileal anastomosis (SG plus), and were followed for 6 to 24 months. A matched coho...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-012-0637-9
更新日期:2012-07-01 00:00:00
abstract::In bariatric surgery, laparoscopic adjustable gastric banding (LAGB) has proven effective in reducing weight and improving obesity-associated comorbidities. Recently, however, laparoendoscopic single-site (LESS) surgery has been proposed to minimize the invasiveness of laparoscopic surgery. The aim of this study is to...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-010-0259-z
更新日期:2011-07-01 00:00:00