Abstract:
BACKGROUND:While numerous promising short-term results of open gastric bypass for morbid obesity were published, the long-term outcome of earlier versions was somewhat disappointing. Thus, it was not until 1993 that this procedure was reintroduced with current modifications and now performed laparoscopically. Published long-term results of gastric bypass are still lacking. METHODS:Out of an original population of 195 patients, we retrospectively analyzed the outcome of 98 patients (82 women, 16 men, mean age 32 years [range 17-54], mean weight 132 kg [range 65-200], mean BMI 46.6 kg/m2) operated on in Erlangen with mean follow-up 22.9 years (range 16.5-25.4). 3 different bariatric operations were performed: horizontal gastroplasty (HGP, n=18), stapled Roux-en-Y gastric bypass (S-RYGBP, n=14) and transected Roux-en-Y gastric bypass (T-RYGBP, n=66). BMI and percentage of excess weight loss (%EWL) were calculated at time 0, and after 1, 2, 3, 10, 15, 20 and 25 years. RESULTS:Statistically significant weight loss was found for the whole patient population at every postoperative time-point compared to preoperative values. Maximal weight loss was achieved mainly during the first 3 years. However, initial and long-term outcome after HGP was significantly worse than after S-RYGBP or T-RYGBP. Gender did not significantly influence the results. CONCLUSION:Traditional open gastric bypass resulted in acceptable and safe long-term weight reduction. It may be assumed that laparoscopic gastric bypass with modern tiny pouch volumes based on the lesser curvature achieves even better and life-long weight reduction.
journal_name
Obes Surgjournal_title
Obesity surgeryauthors
Günther K,Vollmuth J,Weissbach R,Hohenberger W,Husemann B,Horbach Tdoi
10.1381/096089206776116543subject
Has Abstractpub_date
2006-03-01 00:00:00pages
288-96issue
3eissn
0960-8923issn
1708-0428journal_volume
16pub_type
杂志文章相关文献
OBESITY SURGERY文献大全abstract:INTRODUCTION:Obesity in the world has been increasing, and the number of diabetic patients will increase by 114%, and the best treatment results are achieved through surgery. Several techniques have been described; the gastric bypass of an anastomosis (MGB/OAGB) has been gaining popularity for its simplicity and good r...
journal_title:Obesity surgery
pub_type: 临床试验,杂志文章
doi:10.1007/s11695-019-04071-4
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Effectiveness of gastric bypass (GBP) on reduction of vascular risk factors is well established, but GBP induces nutritional deficits that could reduce the cardiovascular benefit of weight loss. Particularly, hyperhomocysteinemia, now clearly identified as a vascular risk factor, has been described after GBP...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-010-0269-x
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Adjustable banding is safe, low invasive, and effective for losing weight. METHODS:69 patients underwent this procedure by laparotomy or laparoscopy. RESULTS:Patients operated by laparotomy lost more weight than those operated by laparoscopy, but in 4 patients we were forced to re-operate in order to remov...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/096089200321643584
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:Gastric electrical stimulation (GES) has been proposed as a promising therapeutic option in treating obesity for 20 years. Currently, the available device of GES cannot meet the clinical needs. The purpose of this study is to verify the effect of a new type of adjustable gastric electrical stimulator in redu...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-013-1037-5
更新日期:2014-01-01 00:00:00
abstract:INTRODUCTION:Laparoscopic single anastomosis gastric bypass (SAGB) is increasingly performed for morbidly obese patients. AIM OF WORK:This pilot study aims primarily at evaluating the incidence of bile gastritis after SAGB. The occurrence of reflux oesophagitis and reflux symptoms were also assessed. PATIENTS AND MET...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-017-2885-1
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Biliopancreatic diversion (BPD) is the most effective bariatric procedure. Around 70% of these patients have secondary hyperparathyroidism (SH) in the long term as a consequence of calcium and vitamin D malabsorption. This work was aimed to study the influence of SH on bone turnover and its relationship with...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-009-0028-z
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:One-anastomosis gastric bypass/mini-gastric bypass (OAGB/MGB) remains controversial because it may cause chronic biliary reflux (BR). The risk of developing esogastric cancer due to BR after OAGB/MGB is based on the results of experimental rat studies using esojejunostomy (EJ). The aim of this study was to a...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-020-04521-4
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Sleeve gastrectomy plus side-to-side jejunoileal anastomosis (JI-SG), a relatively new approach to bariatric surgeries, has shown promising results for treating obesity and metabolic comorbidities. This study investigated the feasibility and safety of JI-SG in weight loss and diabetes remission compared with...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-015-1811-7
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Along with the development of technology, robotic approach is being performed for laparoscopic Roux-en-Y gastric bypass (LRYGB). Some literatures reported same or better peri-operative outcomes with the robotic procedure. The aim of this study is to compare our experience in robot-assisted LRYGB (RA-LRYGB) w...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-015-1884-3
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:Morbid obesity is a risk factor of nonalcoholic steatohepatitis (NASH). Obstructive sleep apnea (OSA) could also be an independent risk factor for elevated liver enzymes and NASH. The relationships between liver injuries and OSA in morbidly obese patients requiring bariatric surgery were studied prospectivel...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-007-9085-3
更新日期:2007-04-01 00:00:00
abstract:BACKGROUND:Overweight and obesity independently increase cardiovascular risk, while even modest weight loss can result in clinically significant improvements in cardiovascular risk and reduce long-term mortality. Lowering the body mass index (BMI) threshold for bariatric surgery to those with moderate obesity might be ...
journal_title:Obesity surgery
pub_type: 杂志文章,评审
doi:10.1007/s11695-013-0877-3
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:A current management dilemma in laparoscopic sleeve gastrectomy (LSG) patients is the development of significant gastroesophageal reflux symptoms after surgery. Treatment is typically directed towards reducing acid reflux despite the surgical removal of parietal cell mass. In contrast, laparoscopic Roux-en-Y...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-014-1480-y
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Susceptibility to obesity is associated with a notable inter-individual variation. The aim of the present study was to compare the effectiveness of sleeve gastrectomy (SG) on weight loss and metabolic profile in obesity-prone (OP) rats vs animals that are non-susceptible to obesity (NSO). METHODS:Young male...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-015-1915-0
更新日期:2016-07-01 00:00:00
abstract:INTRODUCTION:miRNAs are small non-coding RNAs, some of which are expressed in adipose tissues, are present in the circulation, and are regulated in obesity. Bariatric surgery (BS) has been proposed to lead to activation of brown adipose tissue, an effect that may be related to beneficial effects of BS on systemic metab...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-019-04104-y
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Dumping syndrome is not infrequent after laparoscopic Roux-en-Y gastric bypass and could result in dreaded complications, such as hypoglycemia or syncope. Those patients who failed medical therapy and diet modification, regarded as intractable dumping syndrome, may be considered as candidates for revisional ...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-015-1607-9
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Obesity and type 2 diabetes mellitus (T2DM) represent significant healthcare burdens. Surgical management is superior to traditional medical therapy. Laparoscopic sleeve gastrectomy (LSG) and gastric bypass (both Roux-en-Y (RYGB) and one anastomosis gastric bypass (OAGB) are the most commonly performed metab...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-020-04921-6
更新日期:2020-12-01 00:00:00
abstract:INTRODUCTION:Bariatric surgery is considered the most effective treatment for obesity. A recent worldwide survey demonstrated that Laparoscopic Sleeve Gastrectomy (LSG) is the most commonly performed bariatric procedure, while Laparoscopic Adjustable Gastric Banding (LAGB) has been almost abandoned. OBJECTIVES:The aim...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-018-3161-8
更新日期:2018-08-01 00:00:00
abstract::A morbidly obese 42-year-old woman presented with a 1-week history of left chest pain. She had undergone laparoscopic adjustable gastric banding 16 months earlier with a body mass index (BMI) of 49.2 kg/m2. Diagnostic workup revealed a large left pleural empyema and ruled out band slippage. At left thoracotomy, a misd...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-007-9374-x
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Bariatric surgery is the only effective and long-lasting treatment of morbidly obese patients. However, the safety and efficacy of bariatric surgery in patients with hepatitis B viral (HBV) infection is not clear. The aim of the present study is to investigate whether HBV infection influences clinic features...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-007-9346-1
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVE(S):Monitoring and prevention of long-term nutrient deficiency after laparoscopic Roux-en-Y gastric bypass (LRYGB) remains ill defined due to limited surgical follow-up after bariatric surgery. This study compared nutrient supplementation as well as surgeon and primary care physician (PCP) follow-up between pa...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-016-2364-0
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:The aim is to evaluate the effects of IGB in overweight or class I obese patients, by analyzing body composition and quality of life (QOL). METHODS:Prospective study including patients with BMI 27-34.9 kg/m2.body composition analysis (BCA) was performed before IGB implantation and its removal, after 6 month...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-018-3209-9
更新日期:2018-06-01 00:00:00
abstract::We present a novel technique for the retrieval of intragastric balloons used in the treatment of patients with morbid obesity. Although specifically-designed instruments are available for this purpose, this simple technique makes use of instruments that are readily available in an endoscopy suite equipped for simple t...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/0960892052993567
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:The revisional surgery for patients with inadequate weight loss after biliopancreatic diversion with duodenal switch (BPD/DS) is controversial. It has not yet been determined whether a common channel should be shortened or gastric pouch volume reduced. Since the revision of the distal anastomosis remains tec...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/096089203322190907
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND:The authors examined associations between lifetime Axis I and Axis II disorders and weight loss following gastric surgery for morbid obesity. METHODS:44 morbidly obese subjects who had undergone vertical banded gastroplasty (VBG) were systematically interviewed with the Diagnostic Interview Schedule (DIS) a...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1381/096089203322509327
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND:Hepatitis C virus (HCV) is an important cause of liver cirrhosis and its complications. The safety and efficacy of bariatric surgery in patients with HCV infection is not clear. METHODS:Charts were reviewed to identify patients with HCV infection before bariatric surgery. Bariatric surgical patients with no...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-018-3615-z
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Intragastric band migration is an unusual but major long-term complication of gastric banding: its frequency ranges from 0.5-3.8% and always requires removal of the band. Different laparoscopic, laparotomic or endoscopic methods are currently used for band removal. METHODS:571 morbidly obese patients underw...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-007-9060-z
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:Multimodal protocols may enhance postoperative recovery. The aim of this study was to evaluate the influence of a multimodal protocol in the clinical results, insulin resistance, and inflammatory response to trauma in morbidly obese patients undergoing sleeve gastrectomy. METHODS:The population of the study...
journal_title:Obesity surgery
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11695-015-1573-2
更新日期:2015-09-01 00:00:00
abstract::In France, 1,000 obese persons per month undergo a bariatric operation. Obesity surgery requires coordination and monitoring of aftercare. The French public health-care insurer asked the medical associations involved in obesity management to provide guidelines for obesity surgery. The recommendations were developed by...
journal_title:Obesity surgery
pub_type: 杂志文章,评审
doi:10.1381/096089205774859236
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND:The motility of the upper gut after Roux-en-Y gastric bypass (RYGBP) is underexplored. We aimed to investigate the oesophago-gastro-Roux limb motor activity during fasting and after food intake. METHODS:Eighteen morbidly obese patients were examined at least 2 years after RYGBP. A high-resolution manometry ...
journal_title:Obesity surgery
pub_type: 临床试验,杂志文章
doi:10.1007/s11695-015-1639-1
更新日期:2015-10-01 00:00:00
abstract:INTRODUCTION:Obesity is a serious lifestyle disease with various comorbidities and an augmented risk of cancer. Laparoscopic sleeve gastrectomy (LSG) has recently become the most popular bariatric procedure worldwide. While the cost-effectiveness is a major healthcare providers' concern, the point of histological exam ...
journal_title:Obesity surgery
pub_type: 杂志文章
doi:10.1007/s11695-018-3485-4
更新日期:2019-01-01 00:00:00