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Clinical perspectives of the primary spontaneous coronary artery dissection.

Abstract：

:Spontaneous coronary artery dissection is a rare cause of acute coronary syndrome or sudden death. Typically it affects young women during the peripartum period and those using oral contraceptives. The pathophysiology remains unclear, but an eosinophilic periadventitial inflammation has been commonly observed in such cases. Unlike atherosclerotic intimal dissection, the dissection plane in the spontaneous dissection lies within the media or between the media and adventitia. Due to the rarity of the condition, the optimal management of the spontaneous coronary artery dissection has not been established and it may range from conservative medical treatment to percutaneous or surgical interventions depending upon the anatomy of the dissection, compromise of the vessel lumen and the clinical circumstances. The reported prognosis varies widely. Spontaneous coronary artery dissection should be considered in the differential diagnosis in young persons with precordial chest pain, especially women in the peripartum state and those using oral contraceptives. The clinical perspectives of the primary spontaneous coronary artery dissection are elaborated.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Gowda RM,Sacchi TJ,Khan IA

doi

10.1016/j.ijcard.2004.11.029

subject

Has Abstract

pub_date

2005-12-07 00:00:00

pages

334-6

issue

3

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(05)00271-8

journal_volume

105

pub_type

信件,评审

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