Lipopolysaccharide increases gamma-aminobutyric acid synthesis in medial preoptic neurones in association with inhibition of steroid-induced luteinising hormone surge in female rats.

abstract：:During development, melatonin receptors are transiently expressed in multiple neuroendocrine tissues, suggesting a novel role for melatonin in developmental physiology. The best characterised model of melatonin signalling during development is the pars distalis of the rat pituitary. However, although many studies have...

journal_title：Journal of neuroendocrinology

authors： Johnston JD,Klosen P,Barrett P,Hazlerigg DG

更新日期：2006-01-01 00:00:00

abstract：:Regulation of pituitary gonadotrophins by the decapeptide gonadotrophin-releasing hormone 1 (GnRH1) is crucial for the development and maintenance of reproductive functions. A common amino acid sequence for this decapeptide, designated as 'mammalian' GnRH, has been identified in all mammals thus far investigated with ...

journal_title：Journal of neuroendocrinology

authors： Kalamatianos T,du Toit L,Hrabovszky E,Kalló I,Marsh PJ,Bennett NC,Coen CW

更新日期：2005-05-01 00:00:00

abstract：:In the present study, we investigated the effects of the cannabinoid receptor agonist CP55,940 on excitatory and inhibitory synaptic transmission in the rat supraoptic nucleus. Whole-cell patch clamp recordings were performed on supraoptic neurones in in vitro brain slice preparations. CP55,940 significantly reduced t...

journal_title：Journal of neuroendocrinology

authors： Soya A,Serino R,Fujihara H,Onaka T,Ozaki Y,Saito T,Nakamura J,Ueta Y

更新日期：2005-09-01 00:00:00

abstract：:Novel approaches to the characterization of coding carried by spike trains are discussed. Measuring firing frequency alone may only partially reflect spike patterning, and can only quantify changes of the most obvious kind. We have devised a method that combines probabilistic and information approaches to quantify the...

journal_title：Journal of neuroendocrinology

authors： Bhumbra GS,Inyushkin AN,Dyball RE

更新日期：2004-04-01 00:00:00

abstract：:Metabotropic glutamate receptor subtype 7 (mGluR7) is one of the group III mGluRs, which are negatively coupled to adenylate cyclase via Gi/Go proteins and localised to presynaptic active zones of the mammalian central nervous system. We previously reported that mGluR7 is essential for intermale aggression and amygdal...

journal_title：Journal of neuroendocrinology

authors： Masugi-Tokita M,Yoshida T,Kageyama S,Kawata M,Kawauchi A

更新日期：2018-03-01 00:00:00

abstract：:Both insulin and leptin action in the brain are considered to involve activation of phosphoinositide 3-kinase (PI3K), although the roles of different PI3K isoforms in insulin signalling in the hypothalamus are unknown. In the present study, we characterised the roles of these isoforms in hypothalamic insulin and lepti...

journal_title：Journal of neuroendocrinology

authors： Tups A,Anderson GM,Rizwan M,Augustine RA,Chaussade C,Shepherd PR,Grattan DR

更新日期：2010-06-01 00:00:00

abstract：:In addition to its established lactational roles, prolactin acts on multiple target tissues and its circulating levels are responsive to a range of physiological stimuli. The present study used immunohistochemistry to demonstrate that systemic administration of prolactin activates target cells in the arcuate nucleus a...

journal_title：Journal of neuroendocrinology

authors： Kirk SE,Grattan DR,Bunn SJ

更新日期：2019-06-01 00:00:00

abstract：:The novel apelin receptor (APJ receptor, APJR) has a restricted expression in the central nervous system suggestive of an involvement in the regulation of body fluid homeostasis. The endogenous ligand for APJR, apelin, is also highly concentrated in regions that are involved in the control of drinking behaviour. While...

journal_title：Journal of neuroendocrinology

authors： O'Carroll AM,Lolait SJ

更新日期：2003-07-01 00:00:00

abstract：:Proline-, glutamic acid- and leucine-rich protein 1 (PELP1) is an oestrogen receptor (ER) coregulator protein identified by our collaborative group. Work from our laboratory and others has shown that PELP1 is a scaffold protein that interacts with ERs and kinase signalling factors, as well as proteins involved in chro...

journal_title：Journal of neuroendocrinology

authors： Thakkar R,Sareddy GR,Zhang Q,Wang R,Vadlamudi RK,Brann D

更新日期：2018-02-01 00:00:00

abstract：:This study examined whether gonadal steroids are involved in regulating galanin receptor 1 (GalR1) mRNA expression in neurones that contain oestrogen receptor alpha (ERalpha), in three regions of the preoptic area (POA) known to be involved in the control of gonadotropin secretion. Double-labelling immunohistochemistr...

journal_title：Journal of neuroendocrinology

authors： Mitchell V,Lecompte F,Beauvillain JC

更新日期：2004-02-01 00:00:00

abstract：:Much progress has been made during the past 30 years with respect to elucidating the neural and endocrine pathways by which bodily needs for water and energy are brought to conscious awareness through the generation of thirst and hunger. One way that circulating hormones influence thirst and hunger is by acting on neu...

journal_title：Journal of neuroendocrinology

authors： McKinley MJ,Denton DA,Ryan PJ,Yao ST,Stefanidis A,Oldfield BJ

更新日期：2019-03-01 00:00:00

abstract：:Abstract Oxytocin- and vasopressin-binding sites were detected by autoradiography on films and on emulsion-coated sections of rat brains using highly selective [(125)|]-labelled oxytocin and vasopressin antagonists. Two distinct areas with high concentrations of oxytocin-binding sites were detected in the bed nucleus ...

journal_title：Journal of neuroendocrinology

authors： Kremarik P,Freund-Mercier MJ,Stoeckel ME

更新日期：1991-12-01 00:00:00

abstract：:Anabolic androgenic steroids (AAS) are synthetic derivatives of testosterone originally developed for clinical purposes but are now predominantly taken at suprapharmacological levels as drugs of abuse. To date, almost 100 different AAS compounds that vary in metabolic fate and physiological effects have been designed ...

journal_title：Journal of neuroendocrinology

authors： Oberlander JG,Porter DM,Penatti CA,Henderson LP

更新日期：2012-01-01 00:00:00

abstract：:Pituitary tumours are benign but cause significant problems, both because of their compressive effects on brain structures and also because of the syndromes of hormone excess or deficiency that they can cause. Endocrine therapy has become increasingly successful, with the development of dopamine agonists and somatosta...

journal_title：Journal of neuroendocrinology

authors： Davis JR,Trainer PJ

更新日期：2002-12-01 00:00:00

abstract：:Previous electrophysiological studies in the rat suggest that neurons in the diagonal band of Broca participate in baroreceptor-induced suppression of the spontaneous activity of vasopressin-secreting neurons in the hypothalamic supraoptic nucleus. In order to test this hypothesis, extracellular recordings were obtain...

journal_title：Journal of neuroendocrinology

authors： Cunningham JT,Nissen R,Renaud LP

更新日期：1992-06-01 00:00:00

abstract：:Localization in the nervous system of Drosophila melanogaster of a cloned Drosophila muscarinic acetylcholine receptor (mAChR) was investigated using a polyclonal antiserum raised against a peptide corresponding to the predicted receptor carboxyl terminal domain. Immunocytochemical studies on fly sections indicated th...

journal_title：Journal of neuroendocrinology

authors： Harrison JB,Chen HH,Blake AD,Huskisson NS,Barker P,Sattelle DB

更新日期：1995-05-01 00:00:00

abstract：:This study tested the hypothesis that photoperiod affects the ability of testosterone to reduce proopiomelanocortin (POMC) mRNA levels in the arcuate nucleus and luteinizing hormone-releasing hormone (LHRH) mRNA levels in both the preoptic area (POA) or medial basal hypothalamus (MBH). Twenty castrated male sheep were...

journal_title：Journal of neuroendocrinology

authors： Hileman SM,Kuehl DE,Jackson GL

更新日期：1998-08-01 00:00:00

abstract：:The most important zeitgeber for seasonal rhythmicity of physiology and behaviour in birds is the annual cycle of photoperiod. Regulatory mechanisms are less well understood in birds than in mammals since photic information can be perceived by photoreceptors in the retina and the pineal gland, as well as in the brain,...

journal_title：Journal of neuroendocrinology

authors： Brandstätter R

更新日期：2003-04-01 00:00:00

abstract：:It has been well established, particularly in animal models, that oestrogens exert neuroprotective effects in brain areas linked to cognitive processes. A key protective role could reside in the capacity of oestrogen to modulate the inflammatory response. However, the direct neuroprotective actions of oestrogens on ne...

journal_title：Journal of neuroendocrinology

authors： Sarchielli E,Guarnieri G,Idrizaj E,Squecco R,Mello T,Comeglio P,Gallina P,Maggi M,Vannelli GB,Morelli A

更新日期：2020-03-01 00:00:00

abstract：:Studies in rats suggest that neuropeptide Y (NPY) plays a stimulatory role in the generation of the preovulatory luteinizing hormone (LH) surge, via the Y1 receptor. We have investigated this issue using the oestradiol benzoate (EB)-treated ovariectomized (OVX) ewe which is a model for the preovulatory LH surge. A Y1 ...

journal_title：Journal of neuroendocrinology

authors： Estrada KM,Pompolo S,Morris MJ,Tilbrook AJ,Clarke IJ

更新日期：2003-11-01 00:00:00

abstract：:Hypothyroidism during pregnancy and the early postnatal period has severe neurological consequences for the developing offspring. The impact of milder degrees of perturbation of the thyroid axis as encompassed in conditions of subclinical hypothyroidism and hypothyroxinemia, however, has not been established. The pres...

journal_title：Journal of neuroendocrinology

authors： Royland JE,Parker JS,Gilbert ME

更新日期：2008-12-01 00:00:00

abstract：:Prenatal stress is considered as an early epigenetic factor able to induce long-lasting alterations in brain structures and functions. It is still unclear whether prenatal stress can induce long-lasting modifications in the hypothalamo-pituitary-adrenal axis. To test this possibility the effects of restraint stress in...

journal_title：Journal of neuroendocrinology

authors： Henry C,Kabbaj M,Simon H,Le Moal M,Maccari S

更新日期：1994-06-01 00:00:00

abstract：:There are three paralogous genes for gonadotrophin-releasing hormone (GnRH) peptides of vertebrates in general. GnRH1, the protein product of gnrh1 gene, is the hypophysiotrophic neuropeptide, and is a critical regulator of gonadotrophin secretion, whereas GnRH2 and GnRH3 are regarded to have neuromodulatory functions...

journal_title：Journal of neuroendocrinology

authors： Akazome Y,Kanda S,Oka Y

更新日期：2011-07-01 00:00:00

abstract：:The impairment in arginine vasopressin (AVP) secretion during sepsis is described in clinical and experimental studies and has been associated with oxidative stress, apoptosis, and diminished activation of hypothalamic neurons. Few studies have, however, assessed these abnormalities in sepsis survivors. Here we perfor...

journal_title：Journal of neuroendocrinology

authors： Santos-Junior NN,Catalão CH,Costa LH,Rossignoli BB,Dos-Santos RC,Malvar D,Mecawi AS,Rocha MJ

更新日期：2018-05-01 00:00:00

abstract：:Galanin-like peptide (GALP) mRNA is expressed in neurones of the hypothalamic arcuate nucleus and within pituicytes in the neurohypophysis. Several neuropeptides that are expressed in the arcuate nucleus participate in the neuroendocrine regulation of pituitary hormone secretion. Our objective was to determine the ext...

journal_title：Journal of neuroendocrinology

authors： Cunningham MJ,Krasnow SM,Gevers EF,Chen P,Thompson CK,Robinson IC,Smith MS,Clifton DK,Steiner RA

更新日期：2004-01-01 00:00:00

abstract：:The neural and neurochemical substrates regulating reproduction in birds remain vaguely defined. The findings that electrical stimulation in the medial preoptic area (ES/MPOA) or intracerebroventricular infusion of dopamine (DA) stimulated luteinising hormone (LH) and prolactin (PRL) release in female turkeys, led to ...

journal_title：Journal of neuroendocrinology

authors： Al-Zailaie KA,Kang SW,Youngren OM,Thayananuphat A,Bakken T,Chaiseha Y,Millam JR,Proudman JA,El Halawani ME

更新日期：2006-07-01 00:00:00

abstract：:Female Long-Evans rats exhibit stable individual differences in maternal behaviours such as pup licking/grooming and arched-back nursing posture (LG-ABN). These variations in maternal behaviour are accompanied by differences in lactation-induced increases in oxytocin receptor levels in brain regions known to mediate t...

journal_title：Journal of neuroendocrinology

authors： Francis DD,Champagne FC,Meaney MJ

更新日期：2000-12-01 00:00:00

abstract：:The present study aimed to measure the expression of transient receptor potential (TRP) channels in the magnocellular neurones of the paraventricular (PVN) and supraoptic nucleus (SON) in an animal model of hepatic cirrhosis associated with inappropriate vasopressin (AVP) release. In these studies, we used chronic bil...

journal_title：Journal of neuroendocrinology

authors： Nedungadi TP,Carreño FR,Walch JD,Bathina CS,Cunningham JT

更新日期：2012-04-01 00:00:00

abstract：:Opioid effects on synaptic transmission in the mouse supraoptic nucleus (SON) were investigated using whole-cell, patch-clamp techniques. The mu-opioid receptor agonist, [D-Ala(2), N-Me-Phe(4), Gly(5)-ol]-enkephalin (DAMGO) decreased the amplitude of both evoked excitatory postsynaptic currents (eEPSCs) and inhibitory...

journal_title：Journal of neuroendocrinology

authors： Honda E,Ono K,Inenaga K

更新日期：2004-03-01 00:00:00

abstract：:The regional distribution of neurones expressing aromatase mRNA in the ram hypothalamus was examined by in situ hybridization using 33P-labelled cRNA probes. The highest amounts of hybridization signal were observed in the central part of the medial preoptic nucleus and posterior medial part of the bed nucleus of the ...

journal_title：Journal of neuroendocrinology

authors： Roselli CE,Stormshak F,Resko JA

更新日期：2000-07-01 00:00:00