Regulation of rat APJ receptor messenger ribonucleic acid expression in magnocellular neurones of the paraventricular and supraopric nuclei by osmotic stimuli.

abstract：:Vasopressin and its fragment peptides such as [pGlu4, Cyt6]AVP(4-9) (AVP(4-9) represent putative neuromodulators within central nervous homeostatic, memory and behavioural circuits. To localize their central receptor systems, the previously characterized monoclonal anti-idiotypic antibody mAb 237 was employed in immun...

journal_title：Journal of neuroendocrinology

authors： Jurzak M,Fahrenholz F,Gerstberger R

更新日期：1993-10-01 00:00:00

abstract：:The apelin receptor (APJ receptor, APJR) has recently come to prominence following the isolation and identification of its endogenous ligand, apelin, from bovine stomach tissue extracts. Investigation of APJR mRNA expression has revealed a hypothalamic distribution similar to that of vasopressin suggesting that the ap...

journal_title：Journal of neuroendocrinology

authors： O'Carroll AM,Don AL,Lolait SJ

更新日期：2003-11-01 00:00:00

abstract：:In the present study, we investigated the effects of the cannabinoid receptor agonist CP55,940 on excitatory and inhibitory synaptic transmission in the rat supraoptic nucleus. Whole-cell patch clamp recordings were performed on supraoptic neurones in in vitro brain slice preparations. CP55,940 significantly reduced t...

journal_title：Journal of neuroendocrinology

authors： Soya A,Serino R,Fujihara H,Onaka T,Ozaki Y,Saito T,Nakamura J,Ueta Y

更新日期：2005-09-01 00:00:00

abstract：:Psychiatric patients suffering from anxiety disorders or endogenous depression exhibit increased activity in their hypothalamo-pituitary-adrenocortical (HPA) axis. Recently, two Wistar rat lines, bred for high (HAB) and low (LAB) anxiety-related behaviour on the elevated plus-maze, were described as a unique psychopat...

journal_title：Journal of neuroendocrinology

authors： Landgraf R,Wigger A,Holsboer F,Neumann ID

更新日期：1999-06-01 00:00:00

abstract：:In immature neurones, high basal [Cl(-)](i) results in membrane depolarisation following GABA(A) receptor activation, which is critical for various developmental processes including steroid-mediated sexual differentiation of the hypothalamus. Previously, we demonstrated that oestradiol enhances GABA-mediated Ca(2+) in...

journal_title：Journal of neuroendocrinology

authors： Perrot-Sinal TS,Sinal CJ,Reader JC,Speert DB,McCarthy MM

更新日期：2007-04-01 00:00:00

abstract：:During the oestrus cycle, varying spine synapse density correlates positively with varying local synthesis of oestradiol in the hippocampus. In this context, the roles of the oestrogen receptor (ER) subtypes ERα and β are not fully understood. In the present study, we used neonatal hippocampal slice cultures from fema...

journal_title：Journal of neuroendocrinology

authors： Zhou L,Fester L,Haghshenas S,de Vrese X,von Hacht R,Gloger S,Brandt N,Bader M,Vollmer G,Rune GM

更新日期：2014-07-01 00:00:00

abstract：:During development, melatonin receptors are transiently expressed in multiple neuroendocrine tissues, suggesting a novel role for melatonin in developmental physiology. The best characterised model of melatonin signalling during development is the pars distalis of the rat pituitary. However, although many studies have...

journal_title：Journal of neuroendocrinology

authors： Johnston JD,Klosen P,Barrett P,Hazlerigg DG

更新日期：2006-01-01 00:00:00

abstract：:Peripartum hormones and sensory cues from young modify the maternal brain in ways that can render females either at risk for, or resilient to, elevated anxiety and depression. The neurochemical systems underlying these aspects of maternal emotional and mood states include the inhibitory neurotransmitter GABA and the n...

journal_title：Journal of neuroendocrinology

authors： Lonstein JS,Maguire J,Meinlschmidt G,Neumann ID

更新日期：2014-10-01 00:00:00

abstract：:Identification of kisspeptin (Kiss1) and its G protein-coupled receptor 54 (Kiss1r) as an essential component of the hypothalamic-pituitary-gonadal (HPG) axis controlling gonadotrophin secretion raises the possibility that kisspeptin-Kiss1r signalling may play a critical role in the transduction of stress-induced supp...

journal_title：Journal of neuroendocrinology

authors： Kinsey-Jones JS,Li XF,Knox AM,Wilkinson ES,Zhu XL,Chaudhary AA,Milligan SR,Lightman SL,O'Byrne KT

更新日期：2009-01-01 00:00:00

abstract：:The spatial and temporal expression of steroidogenic genes in zebrafish has not been fully characterised. Because zebrafish are increasingly employed in endocrine and stress research, a better characterisation of steroidogenic pathways is required to target specific steps in the biosynthetic pathways. In the present s...

journal_title：Journal of neuroendocrinology

authors： Weger M,Diotel N,Weger BD,Beil T,Zaucker A,Eachus HL,Oakes JA,do Rego JL,Storbeck KH,Gut P,Strähle U,Rastegar S,Müller F,Krone N

更新日期：2018-04-01 00:00:00

abstract：:Abstract The central nervous system of the protochordate ascidian Styela plicata has been investigated by means of immunocytochemical techniques in order to localize peptides of the glucagon/secretin family. In particular, glucagon- and peptide histidine isoleucine-containing neurons were localized in the cortex of th...

journal_title：Journal of neuroendocrinology

authors： Pestarino M

更新日期：1990-10-01 00:00:00

abstract：:Seasonal rhythms in physiology are widespread among mammals living in temperate zones. These rhythms rely on the external photoperiodic signal being entrained to the seasons, although they persist under constant conditions, revealing their endogenous origin. Internal long-term timing (circannual cycles) can be reveale...

journal_title：Journal of neuroendocrinology

authors： Sáenz de Miera C

更新日期：2019-01-01 00:00:00

abstract：:Emerging evidence supports a role of purinergic P2X3 receptors in modulating nociceptive signalling in sensory neurones. Previously, we showed that dorsal root ganglion (DRG) neurones (L1-S1) express both oestrogen receptor (ER)α and ERβ receptors. In the present study, we investigated the expression of P2X3 receptors...

journal_title：Journal of neuroendocrinology

authors： Cho T,Chaban VV

更新日期：2012-05-01 00:00:00

abstract：:The involvement of dopamine receptors in the inhibitory effect of Cholecystokinin octapeptide on ingestive behaviour was investigated. Male rats were infused intraorally with a 1 M solution of sucrose and the amount ingested after treatment with the dopamine receptor agonist apomorphine was compared with that after tr...

journal_title：Journal of neuroendocrinology

authors： Bednar I,Qureshi GA,Södersten P

更新日期：1992-12-01 00:00:00

abstract：:Similar to leptin, resistin acts centrally to increase renal sympathetic nerve activity (RSNA). In high-fat fed animals, the sympatho-excitatory effects of leptin are retained, in contrast to the reduced actions of leptin on dietary intake. In the present study, we investigated whether the sympatho-excitatory actions ...

journal_title：Journal of neuroendocrinology

authors： Habeeballah H,Alsuhaymi N,Stebbing MJ,Badoer E

更新日期：2017-08-01 00:00:00

abstract：:The present study was conducted to visualize neuropeptides in the SCN of a mustelid, the American mink in which seasonal cycles of reproduction rely totally on the annual changes in day length. At this time, data in mustelids are lacking. Results were obtained with in situ hybridization (ISH) using synthetic oligonucl...

journal_title：Journal of neuroendocrinology

authors： Martinet L,Bonnefond C,Peytevin J,Monnerie R,Marcilloux JC

更新日期：1995-01-01 00:00:00

abstract：:RFamide-related peptide-3 (RFRP-3) is a neuropeptide produced in cells of the paraventricular nucleus and dorsomedial nucleus of the ovine hypothalamus. In the present study, we show that these cells project to cells in regions of the hypothalamus involved in energy balance and reproduction. A retrograde tracer (Fluor...

journal_title：Journal of neuroendocrinology

authors： Qi Y,Oldfield BJ,Clarke IJ

更新日期：2009-08-01 00:00:00

abstract：:Rat pituitary homogenates were submitted to differential and density gradient centrifugation. Subcellular fractions as well as the purified secretory granules were examined in electron microscopy, radioimmunological techniques, protease digestion, alkaline treatment and immunoblotting. The global outcome of these expe...

journal_title：Journal of neuroendocrinology

authors： Bollengier F,Geerts A,Matton A,Mahler A,Velkeniers B,Hooghe-Peters E,Vanhaeist L

更新日期：1993-12-01 00:00:00

abstract：:In vivo microdialysis and retrodialysis were used to investigate the role of oxytocin (OXY) release in the mediobasal hypothalamus (MBH) of the ewe in the control of sexual receptivity. Initial experiments showed that OXY release was significantly increased in ovariectomized animals treated with progesterone and oestr...

journal_title：Journal of neuroendocrinology

authors： Kendrick KM,Fabre-Nys C,Blache D,Goode JA,Broad KD

更新日期：1993-02-01 00:00:00

abstract：:Previous studies showed that various stressors can induce delayed (days) and long-lasting (weeks) increases of vasopressin (AVP) stores in terminals of CRH neurons in the external zone of the median eminence (ZEME) in adult rats. Here we tested whether this long-lasting neuroplastic change can be induced by mechanisms...

journal_title：Journal of neuroendocrinology

authors： Schmidt ED,Janszen AW,Binnekade R,Tilders FJ

更新日期：1997-01-01 00:00:00

abstract：:Corticotropin-releasing hormone and arginine vasopressin gene transcription were studied in the parvocellular cells of the hypothalamic paraventricular nucleus in response to both adrenalectomy and the injection of corticosterone. Following 6 days ADX, there was an increase in AVP mRNA, AVP hnRNA and CRH mRNA but not ...

journal_title：Journal of neuroendocrinology

authors： Ma XM,Levy A,Lightman SL

更新日期：1997-10-01 00:00:00

abstract：:Tryptophan is mainly metabolized in the brain through methoxyindole and kynurenine pathways. The methoxyindole pathway produces (among other compounds) melatonin, which displays inhibitory effects on human and animal central nervous systems, including a significant attenuation of excitatory, glutamate-mediated respons...

journal_title：Journal of neuroendocrinology

authors： León J,Vives F,Crespo E,Camacho E,Espinosa A,Gallo MA,Escames G,Acuña-Castroviejo D

更新日期：1998-04-01 00:00:00

abstract：:Abstract The effects of chronic administration of sex steroids on the content of vasoactive intestinal peptide (VIP) in the mediobasal hypothalamus and anterior pituitary were studied in adult rats. Gonadectomy had no effect on VIP concentration in the mediobasal hypothalamus or anterior pituitary gland. Estradiol ben...

journal_title：Journal of neuroendocrinology

authors： Lasaga M,Duvilanski BH,Seilicovich A,Afione S,Diaz Mdel C,Pisera D,Traktenberg R,Debeljuk L

更新日期：1991-02-01 00:00:00

abstract：:The seasonal changes of 2-[125I]iodomelatonin binding were studied using quantitative autoradiography in the pars tuberalis (PT) of the mink, a short-day breeder, kept out of doors. Studies were performed at 7 times of the year (July, September, October, January, February, and May), corresponding to different states o...

journal_title：Journal of neuroendocrinology

authors： Messager S,Caillol M,George D,Martinet L

更新日期：1997-07-01 00:00:00

abstract：:Steroid hormones modulate a variety of physiological functions in the hypothalamus. We attempted to identify steroid-regulated genes in the rat preoptic area-anterior hypothalamus by comparing differentially expressed mRNAs. Adult female rats were ovariectomized and, 1 week later, a silastic capsule containing 17beta-...

journal_title：Journal of neuroendocrinology

authors： Park S,Seong JY,Son GH,Kang SS,Lee S,Kim SR,Kim K

更新日期：2001-06-01 00:00:00

abstract：:In seasonal mammals living in temperate zones, photoperiod regulates prolactin secretion, such that prolactin plasma concentrations peak during the summer months and are lowest during the winter. In sheep, a short-day breeder, circulating prolactin has important modulatory effects on the reproductive system via inhibi...

journal_title：Journal of neuroendocrinology

authors： Christian HC,Imirtziadis L,Tortonese D

更新日期：2015-04-01 00:00:00

abstract：:Opioid effects on synaptic transmission in the mouse supraoptic nucleus (SON) were investigated using whole-cell, patch-clamp techniques. The mu-opioid receptor agonist, [D-Ala(2), N-Me-Phe(4), Gly(5)-ol]-enkephalin (DAMGO) decreased the amplitude of both evoked excitatory postsynaptic currents (eEPSCs) and inhibitory...

journal_title：Journal of neuroendocrinology

authors： Honda E,Ono K,Inenaga K

更新日期：2004-03-01 00:00:00

abstract：:Recent studies have revealed the occurrence of five first exon variants of the rat prolactin receptor mRNA, suggesting that multiple promoters direct prolactin receptor transcription in response to different regulatory factors. In the present study, regional expression of these first exon variants, as well as two prol...

journal_title：Journal of neuroendocrinology

authors： Nogami H,Hoshino R,Ogasawara K,Miyamoto S,Hisano S

更新日期：2007-08-01 00:00:00

abstract：:Ghrelin, an orexigenic hormone released from the empty stomach, provides a gut-brain signal that promotes many appetitive behaviours, including anticipatory and goal-directed behaviours for palatable treats high in sugar and/or fat. In the present study, we aimed to determine whether ghrelin is able to influence and/o...

journal_title：Journal of neuroendocrinology

authors： Bake T,Hellgren KT,Dickson SL

更新日期：2017-04-01 00:00:00

abstract：:NADPH-diaphorase has recently been shown to be the enzyme nitric oxide (NO) synthase, and to be present in the rat supraoptic nucleus (SON) and posterior pituitary. Investigations were carried out to assess whether there is any difference in the extent to which this enzyme is present, as assessed by light-microscopic ...

journal_title：Journal of neuroendocrinology

authors： Pow DV

更新日期：1992-08-01 00:00:00