Abstract:
:In comparing 101 psychotic patients subtyped by DSM-III criteria into paranoia, schizophrenia, schizoaffective, and affective disorders, we failed to distinguish them on the basis of delusional and hallucinatory experiences. These 'productive', 'positive' or 'irritative' symptoms--which the literature tends to link with temporolimbic dysfunction--did not appear specifically linked to schizophrenia. By contrast, 'negative' or 'deficit' symptoms--which the literature tends to relate to frontal lobe dysfunction--appeared more specific--especially for the disorganized subtype of schizophrenia. Although these data tend to support Bleulerian over Schneiderian conceptualization of schizophrenia, the heterogeneity of neuropsychological deficits implied in the negative symptom complexes limits the nosologic utility of the rubric of schizophrenia so defined.
journal_name
Psychopathologyjournal_title
Psychopathologyauthors
Mauri M,Borri C,Giannotti D,Zambotto S,Cassano GB,Akiskal HSdoi
10.1159/000284747subject
Has Abstractpub_date
1992-01-01 00:00:00pages
5-10issue
1eissn
0254-4962issn
1423-033Xjournal_volume
25pub_type
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