Abstract:
OBJECTIVES:To determine the prevalence of depression in a cohort of elderly men as assessed using a 30-item Geriatric Depression Scale (GDS) score and to describe the association between this score and sex steroids, androgen receptor (AR) polymorphism, and general health status. DESIGN:Observational study on the relationship between sex steroid status and health-related parameters. SETTING:Community-based. PARTICIPANTS:Ambulatory men (n=236 in 1997, n=192 in 2000) aged 70 and older at inclusion in 1996, interviewed in 1997 and 2000. MEASUREMENTS:Serum levels of testosterone, estradiol, sex hormone binding globulin (SHBG), dehydroepiandrosterone-sulfate (DHEAS), cortisol, and the AR gene cytosine, adenine, guanine (CAG)-repeat length polymorphism were determined. Free testosterone and free estradiol were calculated. Questionnaires included GDS, 36-item Short Form, and Rapid Disability Rating Scale-2. RESULTS:Median age was 75.3 years (interquartile range=73.5-78.5). A GDS score of 11 or greater was found in 30 (12.7%) men. Age and GDS score were significantly interrelated (P<.01), as were all health-assessment scores. GDS scores were not related to (free) testosterone or AR polymorphism in 1997 or 2000. In 1997 only (n=236), higher GDS scores were related to higher estradiol, free estradiol, and DHEAS levels. CONCLUSION:The data did not support a role for testosterone in depression in elderly community-based men as assessed using the GDS.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
T'Sjoen GG,De Vos S,Goemaere S,Van Pottelbergh I,Dierick M,Van Heeringen C,Kaufman JMdoi
10.1111/j.1532-5415.2005.53212.xsubject
Has Abstractpub_date
2005-04-01 00:00:00pages
636-42issue
4eissn
0002-8614issn
1532-5415pii
JGS53212journal_volume
53pub_type
杂志文章abstract:OBJECTIVES:To determine whether serum levels of 25-hydroxyvitamin D (25(OH)D) and parathyroid hormone (PTH) predict accelerated decline in muscular strength or onset of new disability in mobility and upper extremity functioning over a 3-year follow-up. DESIGN:A community-based prospective cohort study. PARTICIPANTS:S...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.1532-5415.2002.50219.x
更新日期:2002-05-01 00:00:00
abstract:OBJECTIVES:To assess the association between ownership of Chinese elder care facilities and their performance quality and to compare the case-mix profile of residents and facility characteristics in government-owned and private-sector homes. DESIGN:Cross-sectional study. SETTING:Census of elder care homes surveyed in...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.12647
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVES:To determine the effect of differing methods of dispensing wheelchairs. DESIGN:Quasi-experimental by day of week. SETTING:Department of Veterans Affairs Medical Center. PARTICIPANTS:Eighty-four community-dwelling, cognitively intact patients prescribed a standard manual wheelchair. INTERVENTION:A multifa...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2005.53502.x
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVES:To develop and evaluate a model to estimate inpatient resource utilization for seriously ill patients using periodic medical record abstraction and hospital length of stay. DESIGN:A prospective cohort study of prognoses and preferences and outcomes of seriously ill hospitalized adults. The predictive model ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2000.tb03127.x
更新日期:2000-05-01 00:00:00
abstract:OBJECTIVES:To examine whether arterial stiffness is a risk factor for falls in community-dwelling older people. DESIGN:Prospective cohort study. SETTING:Community population, Sydney, Australia. PARTICIPANTS:Community-dwelling older adults (mean age 79.8±4.4, 52.2% female; N=481). MEASUREMENTS:Carotid-femoral pulse ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.12931
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVE:Recent studies have suggested that vascular dementia in older persons is more common than previously hypothesized. A substantial proportion of dementia in old age may be an early manifestation of cerebrovascular disease (CVD), that eventually becomes clinically evident as an acute cerebrovascular accident. Th...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1996.tb00908.x
更新日期:1996-03-01 00:00:00
abstract:OBJECTIVES:To validate the Executive Interview (EXIT25) as a screening instrument for executive cognitive dysfunction in patients with mild dementia. DESIGN:Validation using group comparison and correlation studies. SETTING:The Copenhagen University Hospital Memory Clinic, a multidisciplinary outpatient clinic based ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2005.53470.x
更新日期:2005-09-01 00:00:00
abstract::The relationship between atrial natriuretic peptide (ANP) and age was studied. In elderly subjects (65 to 84 years) higher basal ANP levels were found as compared with those found in young subjects (21 to 23 years). Volume loading (750 mL 0.9% NaCl in 60 minutes) increased ANP levels only in the aged group, and plasma...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1990.tb01502.x
更新日期:1990-11-01 00:00:00
abstract:OBJECTIVES:To examine the cost-effectiveness of a randomized, clinical trial of a home-based intervention for caregivers of people with dementia. DESIGN:This cost-effectiveness analysis examined Resources for Enhancing Alzheimer's Caregivers Health (REACH II), a multisite, randomized, clinical trial, from June 2002 th...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2007.01569.x
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVES:To describe the prevalence of and characteristics associated with major and minor depression in older medical inpatients and to compare associated characteristics by sex and history of depression. DESIGN:Cross-sectional study of two patient samples, with and without a screening diagnosis of major or minor d...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2005.53404.x
更新日期:2005-08-01 00:00:00
abstract:OBJECTIVES:To describe the essential components of an Agile Implementation (AI) process, which rapidly and effectively implements evidence-based healthcare solutions, and present a case study demonstrating its utility. DESIGN:Case demonstration study. SETTING:Integrated, safety net healthcare delivery system in India...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15283
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:The need for mentorship in aging research among postdoctoral trainees and junior faculty across medical disciplines and subspecialties is increasing, yet senior personnel with expertise in aging are lacking to fulfill the traditional dyadic mentorship role. Facilitated peer mentorship is grounded in collabor...
journal_title:Journal of the American Geriatrics Society
pub_type: 评论,杂志文章
doi:10.1111/jgs.15792
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVE:To describe a broad range of physical disability by examining the association between a four-level measure of disability, based on self-report of difficulty in performing functional activities, and previously identified risk factors for disability. DESIGN:Cross-sectional. SETTING:Community-based. PARTICIPA...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1996.tb04065.x
更新日期:1996-12-01 00:00:00
abstract:OBJECTIVES:To examine the association between persistent delirium and 1-year mortality in newly admitted postacute care (PAC) facility patients with delirium who were followed regardless of residence. DESIGN:Observational cohort study. SETTING:Eight greater-Boston skilled nursing facilities specializing in PAC. PART...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2008.02092.x
更新日期:2009-01-01 00:00:00
abstract::This study involved a 1st generation of 194 aged residents at the Philadelphia Geriatric Center plus 2nd and 3rd generations of 357 and 306 offspring, respectively. Serum cholesterol levels (including type of abnormality) and triglyceride levels were determined. The results suggest that hyperlipidemia at all ages is r...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1975.tb00896.x
更新日期:1975-11-01 00:00:00
abstract:OBJECTIVES:To understand characteristics of older at-risk drinkers and reasons why they decide to change or maintain their alcohol consumption. DESIGN:Secondary analysis of data from a randomized controlled trial to reduce drinking in at-risk drinkers. SETTING:Three primary care sites in southern California. PARTICI...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/jgs.12394
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVES:To evaluate the association between pressure-redistributing support surface (PRSS) use and incident pressure ulcers in older adults with hip fracture. DESIGN:Secondary analysis of data from prospective cohort with assessments performed as soon as possible after hospital admission and on alternating days for...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2011.03446.x
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVES:To map the extent, range, and nature of research on the effectiveness, level of use, and perceptions about electronic medication administration records (eMARs) in long-term care facilities (LTCFs) and identify gaps in current knowledge and priority areas for future research. DESIGN:Scoping review of quantit...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/jgs.15384
更新日期:2018-07-01 00:00:00
abstract::The author's concept of loneliness is described, especially as it concerns the elderly. An attempt is made to develop an understanding of the word, with its implications for guidance in the nursing profession. The nurse's defenses against her own feelings of loneliness and depression can inhibit therapeutic interactio...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1978.tb05048.x
更新日期:1978-04-01 00:00:00
abstract:OBJECTIVES:Only limited data are available regarding smoking and health in later life and, in particular, in the older Chinese population. This paper reports the relationship between smoking and mortality in a Chinese cohort aged 70 years and older. SETTING:A population-based study conducted in Hong Kong. PARTICIPANT...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1999.tb01565.x
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVES:To determine the extent of muscle weakness in older female hip fracture patients compared with healthy older and young women; to determine the extent to which this weakness is caused by a decline of the force produced per unit area of muscle rather than by a decline in muscle bulk; and to investigate the mec...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1998.tb02756.x
更新日期:1998-08-01 00:00:00
abstract:OBJECTIVES:To quantify the prevalence of documented urinary tract infection (UTI), nonspecific symptoms, and antibiotic treatment of suspected UTI in nursing homes (NHs) in the tropics and to describe the typical resident likely to receive antibiotic treatment for suspected UTI and factors associated with the developme...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15179
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVES:To determine whether genetic variants in the ciliary neurotrophic factor (CNTF) gene are associated with muscle strength in older women. DESIGN:Cross-sectional analysis of baseline data from the Women's Health and Aging Studies I (1992) and II (1994), complementary population-based studies. SETTING:Twelve ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2006.00693.x
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVE:To identify a set of geriatric conditions as optimal targets for quality improvement to be used in a quality measurement system for vulnerable older adults. DESIGN:Discussion and two rounds of ranking of conditions by a panel of geriatric clinical experts informed by literature reviews. METHODS:A list of 78...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2000.tb04691.x
更新日期:2000-04-01 00:00:00
abstract::As the complexity, prevalence and visibility of ethical dilemmas in medical care of the elderly have grown, hospitals and nursing homes have attempted to develop mechanisms for responding to these difficult ethical issues. While it is known that many hospitals rely on education and advice provided by an ethics committ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1988.tb01786.x
更新日期:1988-02-01 00:00:00
abstract:OBJECTIVES:To examine the effects of dehydroepiandrosterone (DHEA) supplementation on cognitive function and quality of life in healthy older adults. DESIGN:Double-blind, randomized, controlled clinical trial. SETTING:Clinical research facility. PARTICIPANTS:One hundred ten men and 115 women aged 55 to 85 (mean +/- ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2008.01768.x
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVES:To determine the utility of hypodermoclysis in the management of dehydration in nursing home residents and to review the recent literature on the use of clysis in older adults. DESIGN:A retrospective chart review. SETTING:Two continuing care retirement community nursing home units in Cincinnati. PARTICIPA...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/j.1532-5415.1996.tb01870.x
更新日期:1996-08-01 00:00:00
abstract:OBJECTIVES:To investigate the effect of eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA) supplementation on quality of life (QOL). DESIGN:Randomized, double-blind, placebo-controlled trial. SETTING:Independently living individuals from the general older Dutch population. PARTICIPANTS:Three hundred two ind...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2009.02361.x
更新日期:2009-08-01 00:00:00
abstract::Brain atrophy in 154 men and 147 women without neurologic deficits was quantitatively studied by means of computed tomography. The ages ranged from 20 to 79 years. The volume percentage of brain to cranial cavity (Craniocerebral Index, or CCI) was calculated by means of computer programs available in CT systems. The m...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1982.tb07092.x
更新日期:1982-04-01 00:00:00
abstract::To examine the long-term effects of aerobic exercise on the occurrence and time to onset of cardiovascular diagnoses, 184 initially healthy older subjects were randomized into either a long-term exercise group (Group A, n = 80), a short-term exercise group (Group B, n = 42), or a contract control group (Group C, n = 6...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1532-5415.1990.tb03492.x
更新日期:1990-03-01 00:00:00