Abstract:
:By using an analogy between the magnetization of a paramagnetic material in an external magnetic field and the electric polarization of the lateral wall of outer hair cells in response to the transmembrane potential, we show that, based on experimental data on the charge transfer across the membrane, it is impossible to make a statement about the number of possible conformational states of the motor molecule, prestin. Although the choice of model affects the values of derived parameters, such as total charge and motor charge, this is frequently overlooked in the literature.
journal_name
Biophys Jjournal_title
Biophysical journalauthors
Scherer MP,Gummer AWdoi
10.1529/biophysj.105.059782subject
Has Abstractpub_date
2005-05-01 00:00:00pages
L27-9issue
5eissn
0006-3495issn
1542-0086pii
S0006-3495(05)73356-7journal_volume
88pub_type
杂志文章abstract::The efficiency of various patterns of pulsatile stimulation is determined in a model in which a receptor becomes desensitized in the presence of its stimulatory ligand. The effect of stochastic or chaotic changes in the duration and/or interval between successive pulses in a series of square-wave stimuli is investigat...
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