Abstract：
OBJECTIVES:To investigate whether atherosclerosis of the ascending aorta, internal carotid arteries, and coronary arteries is predictive of postoperative delirium in subjects undergoing coronary artery bypass graft (CABG) surgery. DESIGN:Prospective cohort study. SETTING:Boston Veterans Affairs Healthcare System. PARTICIPANTS:Thirty-six male veterans undergoing primary CABG surgery. MEASUREMENTS:Subjects underwent Duplex ultrasound to assess stenosis in the internal carotid arteries. Information on the ascending aortic plaque, as assessed by transesophageal echocardiogram, and the number of coronary vessels bypassed was collected. To create an atherosclerosis score, the number of atherosclerotic areas was added. A validated delirium battery was administered to the subjects preoperatively and on postoperative Days 2 and 5. RESULTS:Fifteen subjects (41.7%) developed delirium postoperatively. In bivariate analysis, carotid stenosis of 50% or more (relative risk (RR)=3.5, 95% confidence interval (CI)=1.5-8.1) and moderate-severe ascending aortic plaque (RR=2.9, 95% CI=1.0-8.5) were significantly associated with the development of delirium. There was a trend toward a significant association for three or more vessels bypassed (RR=9.6, 95% CI=0.6-145.3). After controlling for age, baseline cognition, and medical comorbidity, the atherosclerosis score was significantly associated with postoperative delirium (adjusted RR=2.7, 95% CI=1.1-6.8). CONCLUSION:In this preliminary report, atherosclerosis in the carotid arteries, aorta, and coronary circulation is associated with the development of delirium after CABG surgery. Further investigation into atherosclerosis as a risk factor for delirium is warranted.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Rudolph JL,Babikian VL,Birjiniuk V,Crittenden MD,Treanor PR,Pochay VE,Khuri SF,Marcantonio ERdoi
10.1111/j.1532-5415.2005.53165.xsubject
Has Abstractpub_date
2005-03-01 00:00:00pages
462-6issue
3eissn
0002-8614issn
1532-5415pii
JGS53165journal_volume
53pub_type
杂志文章abstract：OBJECTIVES:To report use of breast cancer treatment (surgery, radiation, and chemotherapy) by patients with Alzheimer's disease (AD). DESIGN:Retrospective cohort study. SETTING:Surveillance, Epidemiology, and End Results (SEER) is a population-based cancer registry covering 14% of the U.S. population. PARTICIPANTS:F...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2005.00467.x
更新日期：2005-11-01 00:00:00
abstract：:Ambulatory cardiac (Holter) monitoring is often recommended in the routine evaluation of patients who fall; however, the prevalence of arrhythmias in old people is high, and the usefulness of such monitoring is unproven. As part of a large study of institutionalized elderly fallers, we compared Holter findings of fall...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1989.tb02639.x
更新日期：1989-05-01 00:00:00
abstract：BACKGROUND:Coffee and tea are two of the most widely consumed beverages worldwide and have been associated with reduced risk of mortality in some studies. However, it is unknown whether consumption of these beverages is associated with survival to an advanced age. OBJECTIVE:To examine associations of coffee and tea co...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.16467
更新日期：2020-09-01 00:00:00
abstract：:Newly enacted Federal regulations have focused increasing attention on the use of psychoactive drugs and on the treatment of disruptive behavior in the nursing home. To study the interaction between resident behavior and staff distress in nursing homes, we measured the frequency of seven types of behavior problems amo...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1991.tb02702.x
更新日期：1991-08-01 00:00:00
abstract：OBJECTIVES:To determine the efficacy of antidepressants in people with depression and dementia. DESIGN:A systematic review and meta-analysis based on a literature search of Medline and Cochrane Trials Registry for acute-phase, double-blind, placebo-controlled, parallel-design, random-assignment trials of antidepressan...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,meta分析,评审
doi：10.1111/j.1532-5415.2011.03355.x
更新日期：2011-04-01 00:00:00
abstract：:This study was undertaken to identify the demographic characteristics of patients aged 55 or older in a drug-overdose group admitted to the Emergency Department of Arizona Health Sciences Center during the 3-year period, August 1975-July 1978. Of the 646 overdose patients observed, 60 (9.5 percent) were aged 55 or old...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1980.tb00004.x
更新日期：1980-12-01 00:00:00
abstract：OBJECTIVES:To identify factors that influence the breast cancer treatment decisions of women aged 80 and older. DESIGN:Medical record review. SETTING:One academic primary care clinic and two community health centers in Boston. PARTICIPANTS:Sixty-five women aged 80 and older diagnosed with breast cancer between 1994 ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2011.03820.x
更新日期：2012-03-01 00:00:00
abstract：:A study was made of 50 patients drawn at random from a Skilled Nursing Facility (SNF) attended by seven physicians. For 59 percent of these patients, polypharmacy was practiced but no substantiating diagnoses were recorded. Approximately half of the drugs were administered pro re nata. More drugs were prescribed in po...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1979.tb04139.x
更新日期：1979-03-01 00:00:00
abstract：OBJECTIVES:To assess the frequency of diagnostic errors in older adults presenting to the emergency department (ED) with symptoms suggestive of Chikungunya virus infection (CVI) and to compare the rates of misdiagnosis of older and younger adults. DESIGN:Cross-sectional study performed in the University Hospitals of M...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.15492
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVES:To determine the utility of hypodermoclysis in the management of dehydration in nursing home residents and to review the recent literature on the use of clysis in older adults. DESIGN:A retrospective chart review. SETTING:Two continuing care retirement community nursing home units in Cincinnati. PARTICIPA...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,评审
doi：10.1111/j.1532-5415.1996.tb01870.x
更新日期：1996-08-01 00:00:00
abstract：OBJECTIVES:To quantify incidence of tooth loss, prosthodontic dental restoration, and chewing difficulty onset and the effect of tooth loss and prosthodontic restoration on chewing difficulty onset. DESIGN:A prospective cohort study of oral health and related behaviors with in-person interviews and clinical examinatio...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2004.52253.x
更新日期：2004-06-01 00:00:00
abstract：PURPOSE:To evaluate the use of a vacuum tumescence device in the treatment of impotence in couples wishing to restore coital function, whose male partners had unsatisfactory results from penile implants or in whom the man was impotent following treatment for prostate or colon carcinoma. SUBJECTS:Convenience sample of ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1992.tb01831.x
更新日期：1992-01-01 00:00:00
abstract：OBJECTIVES:To assess the physical and mental health status of older long-term cancer survivors. DESIGN:Cohort study using propensity score methods to control for baseline differences between cancer survivors and controls. SETTING:General community population in the United States. PARTICIPANTS:Nine hundred sixty-four...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2005.00507.x
更新日期：2005-12-01 00:00:00
abstract：:Older adults often receive suboptimal care during hospitalizations and transitions to postacute settings. Inpatient geriatric services have been shown to increase care quality but have not improved patient outcomes consistently. Acute Care for the Elderly units improve patient outcomes but are resource intensive. Tran...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2009.02682.x
更新日期：2010-02-01 00:00:00
abstract：:Widowed residents of two nursing homes who were oriented to person, time, and place were interviewed to determine the extent to which they had hallucinatory experiences of their deceased spouse. Fifty-two interviews were completed with 46 widows and six widowers. Results are reported for the widows. Twenty-eight (61%)...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1985.tb04619.x
更新日期：1985-08-01 00:00:00
abstract：OBJECTIVES:To determine whether mean leukocyte telomere length (LTL) serves as a biomarker of disability assessed according to activities of daily living (ADLs) and what factors may modify this relationship. DESIGN:Retrospective cross-sectional study. SETTING:A subset of the National Long Term Care Survey (NTLCS), a ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2010.02948.x
更新日期：2010-07-01 00:00:00
abstract：OBJECTIVES:To study how well the scoring on each item of the MMSE relates to the sum-score when the purpose is to identify persons with cognitive impairment, and to identify an equally effective subset of MMSE items for predicting cognitive impairment. DESIGN:Retrospective survey of MMSE data for 850 elderly. SETTING...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1992.tb01804.x
更新日期：1992-11-01 00:00:00
abstract：:A retrospective analysis was made of the records of 100 consecutive geriatric patients with community-acquired bacteremia, admitted to a suburban hospital. The most frequently identified tissue sources for these bacteremias were the urinary tract (34 percent), biliary tract (20 percent), and lungs (13 percent). In 11 ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1980.tb00622.x
更新日期：1980-07-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:Facing penalties for preventable 30-day hospital readmissions, many provider groups have implemented programs to remedy this problem, but the cost efficacy and value of such programs are not well delineated. The objective was to compare total cost of care over 30 days of individuals enrolled in th...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.15203
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVES:To investigate racial and ethnic differences in graft and recipient survival in elderly kidney transplant recipients. DESIGN:Retrospective cohort. SETTING:First-time, kidney-only transplant recipients aged 60 and older of age at transplantation transplanted between July 1996 and October 2010 (N = 44,013). ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.13845
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVES:To evaluate the safety and efficacy of donepezil in the management of patients with Alzheimer's disease (AD) residing in nursing home facilities. DESIGN:Twenty-four-week, randomized, multicenter, parallel-group, double-blind, placebo-controlled trial. SETTING:Twenty-seven nursing homes across the United St...
journal_title：Journal of the American Geriatrics Society
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：2001-12-01 00:00:00
abstract：OBJECTIVES:Insomnia, especially difficulty maintaining sleep, is prevalent among older adults and increases the incidence of falls and fractures. Moreover, the drugs used to treat it exacerbate the risk. Yet current therapies fail to address one of its most common causes in older adults: nocturia and its primary contri...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.16144
更新日期：2019-12-01 00:00:00
abstract：:The literature has identified significant successes in cardiac resuscitation with the use of automated external defibrillators (AEDs) in public areas. As of September 2004, the Food and Drug Administration has authorized the purchase of these devices by the general public without a prescription. For the practicing ger...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,评审
doi：10.1111/j.1532-5415.2005.00569.x
更新日期：2006-01-01 00:00:00
abstract：:Given the American Geriatrics Society's (AGS) commitment to improving health care for older adults by, among other means, educating older people and their caregivers about their health and healthcare choices, the AGS was delighted when, in late 2011, the American Board of Internal Medicine Foundation invited the Socie...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/jgs.12226
更新日期：2013-04-01 00:00:00
abstract：OBJECTIVES:To estimate the cost-effectiveness of an intervention to increase pneumococcal, influenza, and pertussis-containing vaccine uptake in adults aged 65 and older in primary care practices. DESIGN:Markov decision analysis model, comparing the cost-effectiveness of the 4 Pillars Practice Transformation Program w...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1111/jgs.14588
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVES:To search for a potential role of endothelin-1 (ET-1), a potent vasoconstrictor and presumably neurotoxic 21-amino acid peptide, for dysfunction of brain signal processing and cerebrovascular morbidity in nondemented patients with cerebral arteriosclerosis. DESIGN:Cross-sectional study with longitudinal fol...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1997.tb05166.x
更新日期：1997-04-01 00:00:00
abstract：OBJECTIVES:To evaluate the effect of medical Primary Integrated Interdisciplinary Elder Care at Home (PIECH) on acute hospital use and mortality in a frail elderly population. DESIGN:Comparison of acute hospital care use for the year before entering the practice (pre-entry) with the most-recent 12-month period (May 1,...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2012.03965.x
更新日期：2012-07-01 00:00:00
abstract：OBJECTIVES:To determine the relationship between apolipoprotein E (APOE) epsilon4 and Alzheimer's disease (AD) in the Mexican Mestizo population, as well as its effects on the cognitive profile of AD and elderly Mestizos without dementia. DESIGN:Cross-sectional analysis of a cohort study. SETTING:Evaluations were con...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2007.01606.x
更新日期：2008-04-01 00:00:00
abstract：OBJECTIVES:To investigate whether higher circulating levels of C-reactive protein (CRP), interleukin-6 (IL-6), and alpha1-antichymotrypsin (ACT) are associated with worse cognitive function and decline in old age. DESIGN:Two independent population-based cohort studies. SETTING:The Rotterdam Study (mean follow-up 4.6 ...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2007.01159.x
更新日期：2007-05-01 00:00:00
abstract：OBJECTIVES:To determine the performance of the Patient Health Questionnaire 2 (PHQ-2) against the criterion standard for diagnosing major depression, the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), and to examine its performance across age, sex, and racial/ethnic groups. DESIGN:Cros...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2007.01103.x
更新日期：2007-04-01 00:00:00
