Abstract：
:Cleft lip and/or palate (CL/P) are caused by many factors. The aim of this study was to investigate the effects of genetic point mutations in CL/P pathogenesis. ICR and AJ strain mice were used. Ethylnitrosourea (ENU) was injected into 10-week-old male mice (G0) intraperitoneally at a dose of 250 mg/kg. The males were bred with two untreated virgin females of the same strain on day 100 after injection. The uterine contents (G1) of one female were examined on day 18.5 of pregnancy. From the other female, the offspring were delivered naturally, and F3 mice (G3) were also examined in the same way. In ICR strain mice, cleft palate only (CPO) was increased in both the G1 and G3. The frequency was significantly higher in the G3 than the G1 generation. Cleft lip was not observed. In AJ strain mice, CL/P increased in both the G1 and G3. In the G3, the frequency of CPO was increased significantly. Genes related to CPO may be recessive in phenotype. CPO and cleft lip differ from a genetic viewpoint. Point mutations play a significant role in cleft lip and palate.
journal_name
Int J Oral Maxillofac Surgjournal_title
International journal of oral and maxillofacial surgeryauthors
Yamada T,Fujiwara K,Mishima K,Sugahara Tdoi
10.1016/j.ijom.2004.03.004subject
Has Abstractpub_date
2005-01-01 00:00:00pages
74-7issue
1eissn
0901-5027issn
1399-0020pii
S0901502704000980journal_volume
34pub_type
杂志文章abstract：:The solitary fibrous tumour (SFT), also known as a localized fibrous mesothelioma, is a neoplasm characterized by the proliferation of capillaries surrounded by masses of round or spindle-shaped cells. SFT has been discovered in many locations, however, it is extremely rare for SFT to be found in the intraoral region....
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1054/ijom.2001.0201
更新日期：2002-12-01 00:00:00
abstract：:A 7-year-old boy presented in whom a metaphyseal fibrous defect was diagnosed. The lesion was enucleated under local anesthesia. The postoperative course was uneventful and there have been no signs of recurrence as of 14 months after operation. Although rare, metaphyseal fibrous defect should be included in the differ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(05)80834-3
更新日期：1997-04-01 00:00:00
abstract：:During the first counselling after the birth of a child with cleft lip and palate (CLP) information about the malformation should be delivered and a long-standing relationship between the cleft team and the affected family must be established. The present study was conducted to evaluate the parents' experiences, needs...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2009.12.013
更新日期：2010-03-01 00:00:00
abstract：:This study was designed to enumerate the number of perforations to the maxillary sinus while performing apicoectomy on maxillary premolar and molar teeth and to evaluate possible complications as a result of these perforations. A total of 472 apicoectomies were performed in 440 patients; perforations occurred in 10.4%...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：
更新日期：1999-06-01 00:00:00
abstract：:The aim of the present review was to analyze the main clinical signs and symptoms observed in patients with thyroglossal duct cysts (TGDCs). Secondarily we investigated the outcomes following the different types of treatment of TGDCs in children and adults. Three selected strings were run on the PubMed database to ret...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.ijom.2014.07.007
更新日期：2015-01-01 00:00:00
abstract：:Thirty-eight patients with skeletal open bite were studied retrospectively to assess stability of surgical-orthodontic treatment when small plate internal fixation was used. 86% of the sample population showed stable clinical results. Follow-up was from 1-5 years. Only 1 patient experienced skeletal relapse (3%) and 5...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(05)80180-8
更新日期：1991-08-01 00:00:00
abstract：:The advent of customized three-dimensional (3D) printing allows the affordable manufacturing of sophisticated medical devices, thereby providing swift and simple solutions to specific needs in modern healthcare. Meanwhile, certain devices such as industrial mandibular external fixators (EFs) have become less and less ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2020.02.012
更新日期：2020-11-01 00:00:00
abstract：:Posterior capsulitis, which is characterized by pain and inflammation localized above and behind the condyle of the mandible, usually develops as a result of premature contacts in dental occlusion. The pain at the affected side is related to the severe spasm of M. Pterygoideus Lateralis or the splinting action of the ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0300-9785(86)80090-4
更新日期：1986-06-01 00:00:00
abstract：:Many different surgical and non-surgical techniques are used for the treatment of temporomandibular joint (TMJ) hypermobility. One of these methods is autologous blood injection into the TMJ. The fate of the autologous blood used for treatment of recurring condylar dislocation is still not completely understood. The a...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2012.07.001
更新日期：2013-03-01 00:00:00
abstract：:Parotid lymph node (PLN) metastasis greatly worsens the prognosis of patients with oral squamous cell carcinoma (OSCC) and poses a great challenge for further treatment of OSCC. The clinicopathological characteristics and treatment strategies for PLN metastasis from OSCC need to be comprehensively elucidated. A retros...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2020.07.014
更新日期：2020-07-31 00:00:00
abstract：:The purpose of the current retrospective chart review is to describe the outcomes of conservative or surgical treatment of stage 2 bisphosphonate-related osteonecrosis of the jaws (BRONJ). 14 charts (mean patient age 69.07 ± 10.37 years) describing 19 BRONJ stage 2 sites were identified. According to the treatment pro...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,评审
doi：10.1016/j.ijom.2012.05.012
更新日期：2012-11-01 00:00:00
abstract：:The aim of this study was to analyse signs and symptoms present in patients with parotid gland carcinoma and to assess their prognostic value. A retrospective study of data from 131 patients who were treated surgically was performed. Evaluation of prognostic factors was possible in 109 patients who completed a minimum...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2011.12.020
更新日期：2012-07-01 00:00:00
abstract：:No consensus has been reached on the use of dental implants in human immunodeficiency virus (HIV)-positive patients. This systematic review evaluated dental implants in HIV-positive patients in terms of implant survival and success rates, marginal bone loss, and complications. The review was conducted according to the...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2018.02.010
更新日期：2018-10-01 00:00:00
abstract：:This study retrospectively investigates the incidence and risk factors for venous thromboembolism (VTE) in patients undergoing maxillofacial surgery. Data were obtained from patients treated between January 2005 and June 2006. Patients' records were reviewed for complaints and information relating to deep venous throm...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2009.10.024
更新日期：2010-03-01 00:00:00
abstract：:A case of tophaceous pseudogout (i.e., calcium pyrophosphate dihydrate (CPPD) crystal deposition disease) in the temporomandibular joint (TMJ), extending to the base of the skull, is reported. A 38-year-old man was referred to the hospital with mild pain in the right chin and tip of the tongue. Panoramic radiography s...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2016.08.018
更新日期：2017-03-01 00:00:00
abstract：:The technique of camouflage, a non-invasive procedure to correct flaws in the texture and colour of the facial skin, is presented. The acceptance and use of camouflaging by 52 patients with different diagnoses are presented. The advantages of camouflaging are discussed in comparison to medical tattooing. ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
abstract：:The increasing incidence of oral squamous cell carcinoma (SCC) especially among younger people has been observed in many parts of the world. The objective of this study was to delineate the profile of patients with oral SCC with an emphasis on younger people in northern Thailand between 1991-2000. The medical records ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1054/ijom.2003.0503
更新日期：2004-01-01 00:00:00
abstract：:A case of metastatic osteosarcoma in the submental vestibule of the oral cavity and the lung is described in an 18-year-old male with primary osteosarcoma occurring in the sacrum. Dissemination of osteosarcoma to other organs, especially early to the lung, is common, but its metastasis to the oral mucosa has been rare...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2006.04.004
更新日期：2006-11-01 00:00:00
abstract：:The aim of this study was to evaluate the long-term survival of craniofacial implants and prostheses and to identify factors associated with failure in a cohort of patients. A 25-year retrospective analysis was conducted at Royal Melbourne Hospital. Data included demographic characteristics, age, site and cause of the...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2018.01.013
更新日期：2018-06-01 00:00:00
abstract：:This technical note demonstrates the benefits of preoperative planning, involving the use of rapid prototype models and rehearsal of the surgical procedure, using image-guided navigational surgery. Optimum reconstruction of large defects can be achieved with this technique. ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2013.04.019
更新日期：2013-08-01 00:00:00
abstract：:The purpose of this study was to determine whether orbital reconstruction with customized implants can correct post-traumatic orbital deformities such as late enophthalmos and delayed diplopia. The hypothesis proposed was that an overcorrection of the orbital volume is needed to resolve enophthalmos. A retrospective o...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2016.04.007
更新日期：2016-09-01 00:00:00
abstract：:This investigation compared the results of 2 types of wound closure after mandibular third molar removal. In both the test group and the control group, the molars were removed using a mucoperiosteal flap as described by Szmyd; a wedge of tissue distal to the second molar was removed before closure to secure self-irrig...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(88)80164-4
更新日期：1988-04-01 00:00:00
abstract：:The aim of this study was to investigate the position and course of the mandibular canal through the mandibular ramus using computed tomographic (CT) imaging and to relate the findings to performing sagittal split ramus osteotomies. The mandibles of 35 patients with skeletal Class III prognathism with symmetry (12 mal...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2004.06.001
更新日期：2005-05-01 00:00:00
abstract：:From 47 anatomic specimens, vertical sections were cut in the molar region, and computer-assisted measurements of both height and width of the alveolar ridge were made to assess the available bone volume for endosseous implant placement. The mean ridge heights ranged between 9.30 and 3.23 mm, the highest and lowest va...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(95)80029-8
更新日期：1995-08-01 00:00:00
abstract：:Septic arthritis of the temporomandibular joint (TMJ) has a high morbidity, is infrequently reported, and has been described almost exclusively in adults. We present two cases of septic arthritis of the TMJ that occurred in children after minor blunt trauma. Literature related to septic arthritis of the TMJ was review...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,评审
doi：10.1016/s0901-5027(05)80519-3
更新日期：1993-10-01 00:00:00
abstract：:Arthroscopy of the rabbit temporomandibular joint was evaluated experimentally on 22 rabbits. A small arthroscope with so-called "Selfoc"-system was employed. The reaction to arthroscopy was analyzed clinically. Macroscopic dissection and histology were then employed to detect possible pathological changes in the join...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0300-9785(86)80137-5
更新日期：1986-04-01 00:00:00
abstract：:This study is a retrospective review of the records of all cases treated in the authors' department since 1991 to identify patients with condylar masses diagnosed as osteochondromas. In 2186 cases of benign and malignant cysts/tumours of the maxillofacial region (1560 malignant and 626 benign), 8 osteochondromas of th...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,评审
doi：10.1016/j.ijom.2010.02.015
更新日期：2010-06-01 00:00:00
abstract：:A case of large cell neuroendocrine carcinoma (LCNEC) of the tongue base is described. It was characterized by solid tumor nests with central necrosis and rosette formation resembling basaloid squamous cell carcinoma. Immunohistochemical examination revealed that this tumor had neuroendocrine differentiation. It was d...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2008.12.012
更新日期：2009-03-01 00:00:00
abstract：:The aim of this study was to compare the postoperative stability of the mandible after a bilateral lengthening procedure, either by bilateral sagittal split osteotomy (BSSO) or distraction osteogenesis (DOG). All patients who underwent mandibular advancement surgery between March 2001 and June 2004 were evaluated; 26 ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2008.09.007
更新日期：2009-01-01 00:00:00
abstract：:Systemic sclerosis (SSc) is a relatively rare condition characterized by the excessive production and deposition of collagen within tissue. This condition is thought to be immunologically mediated and, in addition to its notorious cutaneous manifestations, often involves multiple organs. A case is presented of systemi...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2007.07.025
更新日期：2008-02-01 00:00:00
