Omeprazole is more effective than a histamine H2-receptor blocker for maintaining a persistent elevation of gastric pH after colon resection for cancer.

Abstract:

BACKGROUND:An assessment was made of the change and the effect of a histamine H(2)-receptor blocker (H(2)-blocker) or omeprazole on gastric pH after surgery. METHODS:Eighty patients who underwent colon resection for colorectal cancer were divided into groups of 20. Group I received neither H(2)-blocker nor omeprazole. Group II received cimetidine hydrochloride 1,200 mg daily, group III received ranitidine hydrochloride 200 mg daily, group IV received omeprazole 40 mg twice daily for 5 days. Gastric juice was measured preoperatively and then twice daily until the fifth postoperative day. RESULTS:The gastric pH decreased after surgery. The gastric pH increased on the first postoperative day after the administration of H(2)-blockers (P <0.001), but started to decrease on the second postoperative day. The gastric pH increased and remained high throughout the study period for the omeprazole group (P <0.001). CONCLUSIONS:The administration of an H(2)-blocker can significantly elevate the gastric pH value for patients after resection of colorectal cancer, but only lasts for 24 to 48 hours. Omeprazole is more effective than an H(2)-blocker at maintaining a persistent elevation of gastric pH.

journal_name

Am J Surg

authors

Hsu TC,Su CF,Leu SC,Huang PC,Wang TE,Chu CH

doi

10.1016/j.amjsurg.2002.10.002

subject

Has Abstract

pub_date

2004-01-01 00:00:00

pages

20-3

issue

1

eissn

0002-9610

issn

1879-1883

pii

S0002961003004318

journal_volume

187

pub_type

临床试验,杂志文章,随机对照试验
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    journal_title:American journal of surgery

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    doi:10.1016/0002-9610(79)90115-6

    authors: Brown PW

    更新日期:1979-04-01 00:00:00

  • Hypoalbuminemia at admission is associated with increased incidence of in-hospital complications in geriatric trauma patients.

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    doi:10.1016/j.amjsurg.2015.06.013

    authors: Garwe T,Albrecht RM,Stoner JA,Mitchell S,Motghare P

    更新日期:2016-07-01 00:00:00

  • Treatment and outcome of patients with chest wall recurrence after mastectomy and breast reconstruction.

    abstract:BACKGROUND:Chest wall recurrence (CWR) in the setting of previous mastectomy and breast reconstruction can pose complex management dilemmas for clinicians. We examined the impact of breast reconstruction on the treatment and outcomes of patients who subsequently developed a CWR. METHODS:Between 1988 and 1998, 155 brea...

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    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2003.11.006

    authors: Chagpar A,Langstein HN,Kronowitz SJ,Singletary SE,Ross MI,Buchholz TA,Hunt KK,Kuerer HM

    更新日期:2004-02-01 00:00:00

  • Peptide YY augments postprandial small intestinal absorption in the conscious dog.

    abstract::Since feeding increases intestinal fluid and electrolyte losses in short bowel syndrome, an agent increasing postprandial small bowel absorption might have a therapeutic role. Peptide YY (PYY) has recently been shown to increase net small bowel absorption under basal conditions. The aim of this study was to determine ...

    journal_title:American journal of surgery

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    doi:10.1016/0002-9610(94)90100-7

    authors: Bilchik AJ,Hines OJ,Zinner MJ,Adrian TE,Berger JJ,Ashley SW,McFadden DW

    更新日期:1994-06-01 00:00:00

  • Impact of intraoperative myocardial tissue acidosis on postoperative adverse outcomes and cost of care for patients undergoing prolonged aortic clamping during cardiopulmonary bypass.

    abstract:BACKGROUND:This study examined the impact of intraoperative myocardial acidosis and adverse postoperative outcomes on the cost of cardiac surgical care. METHODS:Myocardial tissue pH corrected to 37 degrees C (pH(37C)) was measured in 162 patients with cross-clamp (XC) duration of 119 minutes or longer. Perioperative d...

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    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2008.01.023

    authors: Healey CM,Kumbhani DJ,Healey NA,Crittenden MD,Gibson SF,Khuri SF

    更新日期:2009-02-01 00:00:00

  • EEA esophageal stapling for control of bleeding esophageal varices.

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    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(80)90125-7

    authors: Cooperman M,Fabri PJ,Martin EW Jr,Carey LC

    更新日期:1980-12-01 00:00:00

  • A survey of robotic surgery training curricula in general surgery residency programs: How close are we to a standardized curriculum?

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    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2018.11.006

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    更新日期:2019-02-01 00:00:00

  • Free tissue transfer to extend the limits of limb salvage for lower extremity tissue loss.

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    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(97)00175-x

    authors: Gooden MA,Gentile AT,Mills JL,Berman SS,Demas CP,Reinke KR,Hunter GC,Westerband A,Greenwald D

    更新日期:1997-12-01 00:00:00

  • Colorectal carcinoma associated with ulcerative colitis: a study of prognostic indicators.

    abstract::Fifty-two patients with ulcerative colitis and colorectal cancer undergoing colectomy at the Mount Sinai Hospital between 1973 and 1988 were studied retrospectively to determine the correlation of age, sex, duration of colitis, tumor location, number of cancers, tumor differentiation, colloid content, presence of sign...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(05)80638-5

    authors: Heimann TM,Oh SC,Martinelli G,Szporn A,Luppescu N,Lembo CA,Kurtz RJ,Fasy TM,Greenstein AJ

    更新日期:1992-07-01 00:00:00

  • Enhanced recovery after surgery: A clinical review of implementation across multiple surgical subspecialties.

    abstract::Enhanced recovery after surgery (ERAS) is a multimodal protocol applied towards perioperative patient care. ERAS programs are implemented by a multidisciplinary team centered around the patient, incorporating outpatient clinical staff, preoperative nurses, anesthesiologists, operative nurses, postoperative recovery st...

    journal_title:American journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1016/j.amjsurg.2019.11.009

    authors: Smith TW Jr,Wang X,Singer MA,Godellas CV,Vaince FT

    更新日期:2020-03-01 00:00:00

  • Misdiagnosis of primary epiploic appendagitis.

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    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(98)00103-2

    authors: Rao PM,Rhea JT,Wittenberg J,Warshaw AL

    更新日期:1998-07-01 00:00:00

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    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2012.10.044

    authors: Hu W,Liang Y,Zhang S,Hu Y,Liu J

    更新日期:2013-09-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:2011-07-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1016/0002-9610(75)90472-9

    authors: Attie JN,Khafif RA

    更新日期:1975-10-01 00:00:00

  • Total infrarenal aortic occlusion.

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    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(77)90331-2

    authors: Casali RE,Tucker E,Read RC,Thompson BW

    更新日期:1977-12-01 00:00:00

  • Hemodynamic performance of carotid artery shunts.

    abstract::Although the use of shunts for carotid artery surgery remains controversial, the hemodynamics of the shunts currently available have not been carefully evaluated in vivo. We developed an animal model using contralateral carotid artery ligation, which produced ipsilateral carotid blood flows (640 +/- 44 ml/min) and int...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(89)90354-1

    authors: Aufiero TX,Thiele BL,Rossi JA,Miller CA,Neumyer MM

    更新日期:1989-08-01 00:00:00

  • Specific but limited role of new imaging techniques in decision-making about intraabdominal abscesses.

    abstract::Despite the very high accuracy rate of imaging studies (ultrasound, computed tomography, liver-lung-spleen scans and gallium-67 scans) in detecting intraabdominal abscesses, our experience with 80 recent cases indicate that these techniques have not significantly altered traditional methods of decision-making about wh...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(82)90195-7

    authors: Wright HK,Dunn E,MacArthur JD,Pelliccia O

    更新日期:1982-04-01 00:00:00

  • A simple method to control intractable bleeding after endoscopic sphincterotomy.

    abstract::A successful method for controlling intractable bleeding after endoscopic sphincterotomy is described. By passing a Fogarty catheter into the duodenum, balloon tamponade of the bleeding point is possible. By such a technique, major resective surgery can be avoided. ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(94)90092-2

    authors: Bardaxoglou E,Campion JP,Maddern G,Siriser F,Launois B

    更新日期:1994-02-01 00:00:00

  • Percutaneous Denver peritoneovenous shunt insertion.

    abstract::A simplified technique for insertion of a peritoneovenous shunt is described. By using a "peel-away" sheath at both ends of the shunt, the insertion is much quicker and less traumatic to the patient. ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(06)80078-4

    authors: Weaver DW,Wiencek RG,Bouwman DL

    更新日期:1990-06-01 00:00:00

  • Synchronous non-small cell lung cancers.

    abstract:INTRODUCTION:The few series of synchronous lung cancers have included small cell and carcinoid tumors. We wished to determine the prognosis for patients with synchronous non-small cell lung cancer (NSCLC). METHODS:A database of 3034 lung cancer patients was reviewed for synchronous NSCLC. Survival was determined by Ka...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/S0002-9610(96)00019-0

    authors: Pommier RF,Vetto JT,Lee JT,Johnston KM

    更新日期:1996-05-01 00:00:00

  • Single-port laparoscopic colectomy is safe and feasible in patients with previous abdominal surgery.

    abstract:BACKGROUND:The aim of this study was to assess the impact of previous abdominal surgery (PAS) on single-port laparoscopic colectomy (SPLC). METHODS:We studied 429 consecutive patients who underwent SPLC in our department from May 2009 to December 2013. Patients were divided into 2 groups: those with PAS (PAS group) an...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2014.06.015

    authors: Tei M,Wakasugi M,Omori T,Ueshima S,Tori M,Akamatsu H

    更新日期:2015-06-01 00:00:00

  • Sex-based differences in mitral valve Re-operation after mitral valve repair: Truth or myth?

    abstract:BACKGROUND:Outcomes after mitral valve (MV) repair are known to be worse in women. Less is known about sex-based differences in MV repair durability. METHODS:All adult patients undergoing MV repair from 2002 to 2016 were reviewed. Of 2463 cases, 947 (39%) were women. Re-operation risk was defined as any intervention f...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2020.06.069

    authors: Hirji SA,Guetter CR,Trager L,Yazdchi F,Landino S,Lee J,Anastasopulos A,Percy E,McGurk S,Pelletier MP,Aranki S,Shekar PS,Kaneko T

    更新日期:2020-11-01 00:00:00

  • Primary nonphylloides breast sarcomas.

    abstract:BACKGROUND:The prevalence of primary breast sarcoma is low, occurring in fewer than 1% of women with breast malignancies. The purpose of this study was to examine the presentation, treatment, and prognosis of patients presenting with these neoplasms. METHODS:This was a retrospective review of patients with a primary b...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/s0002-9610(03)00269-1

    authors: Blanchard DK,Reynolds CA,Grant CS,Donohue JH

    更新日期:2003-10-01 00:00:00

  • Overutilization of regional burn centers for pediatric patients--a healthcare system problem that should be corrected.

    abstract:BACKGROUND:Minor burns represent .96% to 1.5% of emergency department visits, yet burn center referral is common. Analysis of the Grady Memorial Hospital Burn Center examined the feasibility and savings if pediatric burns were managed locally with as-needed consultation. METHODS:Prospective data on 219 consecutive adm...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2011.06.036

    authors: Vercruysse GA,Ingram WL,Feliciano DV

    更新日期:2011-12-01 00:00:00

  • Standard D2 versus extended D2 (D2+) lymphadenectomy for gastric cancer: an interim safety analysis of a multicenter, randomized, clinical trial.

    abstract:BACKGROUND:A multicenter, randomized, clinical trial was initiated to evaluate the possible benefits of extended D2 (D2+) lymphadenectomy after potentially curative resection of gastric cancer. METHODS:Standard D2 lymphadenectomy was defined according to the Japanese Gastric Cancer Association classification. D2+ lymp...

    journal_title:American journal of surgery

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.amjsurg.2006.04.018

    authors: Kulig J,Popiela T,Kolodziejczyk P,Sierzega M,Szczepanik A,Polish Gastric Cancer Study Group.

    更新日期:2007-01-01 00:00:00

  • Carcinoma of the lip.

    abstract::(1) Carcinoma of the lip occurs predominantly in men in their seventh and eighth decades of life. (2) Epidermoid carcinoma is the most common malignant lip tumor. (3) Metastases to cervical lymph nodes are uncommon. (4) Elective neck dissection is not indicated. (5) Therapeutic radical neck dissection can benefit the ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(79)90427-6

    authors: Heller KS,Shah JP

    更新日期:1979-10-01 00:00:00

  • Recurrent ventricular tachycardia: how effective is surgical management?

    abstract::Previous "blind" surgical intervention for recurrent, sustained ventricular tachycardia has been disappointing. Successful surgical intervention requires that a local arrhythmia circuit be interrupted, ablated, or disengaged from the adjacent healthy myocardium while incurring minimal injury to the remaining functiona...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(83)90128-9

    authors: Harken AH,Josephson ME

    更新日期:1983-06-01 00:00:00

  • Tibial artery injuries.

    abstract::Twenty-eight consecutive patients with tibial or peroneal artery injury are reported. Of these, eight underwent direct arterial repair, eight received vein graft reconstruction, and the involved artery was ligated in the remainder, with amputation required for various reasons in four. Tibial or peroneal artery injury ...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/0002-9610(82)90021-6

    authors: Holleman JH Jr,Killebrew LH

    更新日期:1982-09-01 00:00:00

  • Surgical skills curricula in American College of Surgeons Accredited Education Institutes: An international survey.

    abstract:BACKGROUND:A clear understanding of simulation-based curricula in use at American College of Surgeons Accredited Education Institutes (ACS-AEIs) is lacking. METHODS:A 25-question online survey was sent to ACS-AEIs. RESULTS:The response rate approached 60%. The most frequent specialties to use the ACS-AEIs are general...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2016.08.011

    authors: Ghaderi I,Fitzgibbons S,Watanabe Y,Lachapelle A,Paige J,Association for Surgical Education Simulation Committee.

    更新日期:2017-04-01 00:00:00

  • High-resolution computed tomography accurately predicts resectability in hilar cholangiocarcinoma.

    abstract:INTRODUCTION:Despite the use of radiologic, endoscopic, and laparoscopic staging techniques, the rate of nontherapeutic laparotomies in patients with hilar cholangiocarcinoma remains high. This study evaluated the accuracy of preoperative high-resolution computed tomography (HRCT) to determine resectability in this set...

    journal_title:American journal of surgery

    pub_type: 杂志文章

    doi:10.1016/j.amjsurg.2006.10.024

    authors: Aloia TA,Charnsangavej C,Faria S,Ribero D,Abdalla EK,Vauthey JN,Curley SA

    更新日期:2007-06-01 00:00:00