Abstract：
:Polyadenylated RNA was isolated from nuclei of cultured Drosophila cells, Schneider's line 2, and used as a template to synthesize a complementary DNA probe. Hybridization experiments were performed to study the relationship between nuclear and cytoplasmic RNA. About two-thirds of the nuclear polyadenylated RNA sequences exist in the cytoplasm. Experiments with fractionated cDNA probes demonstrated that RNA sequences that are frequent in the nucleus are also abundant in the cytoplasm. These findings are consistent with a precursor-product relationship in which some polyadenylated molecules in the nucleus are destined for the cytoplasm while other sequences are polyadenylated but not transferred.
journal_name
Biochemistryjournal_title
Biochemistryauthors
Levy B,McCarthy BJdoi
10.1021/bi00656a026subject
Has Abstractpub_date
1976-06-01 00:00:00pages
2415-9issue
11eissn
0006-2960issn
1520-4995journal_volume
15pub_type
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