Abstract:
OBJECTIVES:The relationship between the efficacy of the anticholinergic action of disopyramide, cibenzoline and aprindine and age was examined in patients with paroxysmal and persistent atrial fibrillation. METHODS:This prospective, randomized study included 278 patients (200 men, 78 women, mean age 61 +/- 11 years) divided into two groups; the non-elderly group (age below 60 years) and the elderly group (age over 60 years). Successful termination was defined as conversion of sinus rhythm within 30 min of intravenous administration of 50 mg disopyramide (n = 91), 70 mg cibenzoline (n = 93) or 100 mg aprindine (n = 94) in this prospective and randomized study. RESULTS:No statistically significant difference was found in patient characteristics between the three agents. 1) The rate of conversion to sinus rhythm after disopyramide administration in the non-elderly group(37.8%) was significantly higher than that in the elderly group (17.4%, p = 0.0361). 2) The rate of conversion to sinus rhythm after cibenzoline administration in the non-elderly group (62.2%) tended to be greater than that in the elderly group (43.8%, p = 0.0972). 3) The rate of conversion to sinus rhythm after aprindine administration in the non-elderly group (25.6%) was not significantly higher than that in the elderly group (18.2%, p = 0.4474). CONCLUSIONS:The anticholinergic action of antiarrhythmic agents has an effect on successful termination in non-elderly patients with paroxysmal and persistent atrial fibrillation.
journal_name
J Cardioljournal_title
Journal of cardiologyauthors
Komatsu T,Nakamura S,Suzuki O,Yomogida K,Horiuchi D,Abe N,Kameda K,Owada S,Tomita H,Oikawa K,Okumura Ksubject
Has Abstractpub_date
2003-04-01 00:00:00pages
191-8issue
4eissn
0914-5087issn
1876-4738journal_volume
41pub_type
杂志文章abstract:OBJECTIVES:Nifekalant is a class III antiarrhythmic drug, which prolongs the refractory period of the atrial and ventricular myocardium, without negative inotropic action. Intravenous nifekalant was administered in four patients with atrial tachyarrhythmia and severe heart failure to terminate or prevent atrial tachyar...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2002-03-01 00:00:00
abstract::To define the histopathogenesis of successful and unsuccessful recanalization following selective intracoronary thrombolysis, coronary angiography (CAG) in thrombolysis and histologic findings were compared in 13 patients who died within four days (mean 1.5 days) after the procedure. Thirteen infarct-related arteries ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1989-06-01 00:00:00
abstract::An 83-year-old woman presented with dilated cardiomyopathy. Cardiac resynchronization therapy was performed. Two weeks later, cardiac output and ventricular wall motion were estimated using impedance cardiography and tissue Doppler echocardiography with and without pacing. Cardiac output increased from 3.5 to 4.5 l/mi...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2003-07-01 00:00:00
abstract::Little is known about the efficacy and safety of intensive lowering of low-density lipoprotein cholesterol (LDL-C) with statin/ezetimibe therapy after coronary stent implantation in patients with stable angina. Fifty patients with stable angina were randomly divided into an atorvastatin (10 mg/day) (A) group and an at...
journal_title:Journal of cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jjcc.2012.03.002
更新日期:2012-08-01 00:00:00
abstract::This study qualified the severity and localization of reverse redistribution of technetium-99 m (Tc)-tetrofosmin rest imaging. Both Tc-tetrofosmin and thallium-201 (Tl) rest imaging with early images and delayed images were obtained in the subacute phase of myocardial infarction in 21 patients with first anterior myoc...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1999-07-01 00:00:00
abstract::A 32-year-old woman presented with a rare case of tricuspid valve endocarditis causing inflammatory reopening of the spontaneously closed ventricular septal defect (VSD), associated with aortic valve malformation. She was admitted to our hospital because of fever lasting 4 weeks. Severe aortic regurgitation was reveal...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Missense mutations in KCNH2, a gene encoding the Kv11.1 channel, cause long QT syndrome (LQTS) type 2 primarily by disrupting the intracellular transport of Kv11.1 to the plasma membrane. The present study aimed to clarify the functional changes by two novel KCNH2 missense mutations. METHODS:We performed ge...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2017.10.004
更新日期:2018-04-01 00:00:00
abstract::Ischemic heart disease is the leading cause of morbidity and mortality in a worldwide epidemic. Myocardial ischemia is characterized by an imbalance between myocardial oxygen supply and demand, causing cardiac dysfunction, arrhythmias, myocardial infarction, and sudden death. Various clinical ischemic manifestations a...
journal_title:Journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jjcc.2008.07.016
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVES:Brain natriuretic peptide (BNP) and QRS duration have been reported as independent predictors for cardiac events in patients with heart failure. The present study investigated the relationships between BNP and QRS duration to assess the prognostic value in patients with heart failure. METHODS:We prospective...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND:The effect of elevated blood glucose (BG) levels on the long-term prognosis of acute decompensated heart failure (ADHF) patients has not been well defined. The purpose of this study is to evaluate the long-term prognosis of ADHF with elevated BG. METHODS:A cohort of patients consecutively admitted to the ca...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2016.05.013
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Although several clinical studies have evaluated plasma adiponectin levels in response to chronic heart failure, little is known about the relation between cardiac function and metabolic factors including adiponectin in patients with acute myocardial infarction (AMI). METHODS AND RESULTS:We analyzed 50 cons...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2008.08.012
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:The relation between systolic blood pressure (sBP) on admission and the extent of fluid re-distribution in patients with acute heart failure (AHF) remains unclear. This study aimed to investigate this relation. METHODS:We enrolled consecutive patients who were admitted for AHF in our cardiology department a...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2019.03.003
更新日期:2019-09-01 00:00:00
abstract::Serial echocardiographic analyses of the left ventricle (LV) were performed in 61 patients with aortic regurgitation before, one-six months, and six years after aortic valve replacement (AVR). There was no significant difference in the preoperative hemodynamic and echocardiographic data between 54 survivors and six de...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1989-06-01 00:00:00
abstract:BACKGROUND:Recurrence after catheter ablation of persistent atrial fibrillation (AF) remains an unsolved issue. This study aimed to explore the association between the left atrial appendage peak flow velocity (LAAV) and AF recurrence after ablation in persistent AF patients. METHODS:Fifty-three consecutive patients wh...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2015.04.009
更新日期:2015-11-01 00:00:00
abstract::Although the mechanism for the occurrence of acute myocardial infarction (MI) has been investigated by many pathological and clinical studies, it has not been adequately clarified yet. Although the disruption of vulnerable plaque is a well-known cause of acute MI, there are many silent plaque disruptions detected in t...
journal_title:Journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jjcc.2020.08.007
更新日期:2020-09-10 00:00:00
abstract::This is a report of 3 cases of cardiac sarcoidosis. None of the 3 patients had other overt systemic involvement. Multinucleated giant cells and non-caseating epithelial cell granulomas with small lymphocytic infiltrations were detected in the endomyocardial biopsy specimen. Some focal left ventricular wall motion abno...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Nowadays, early detection and treatment can often keep chronic kidney disease patients from getting worse and prevent the occurrence of cardiovascular disease. Cystatin C (Cys-C) is a new marker for renal dysfunction. This study investigated whether Cys-C played an important role for screening coronary arter...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2009.06.003
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:A single and local administration of L-arginine after balloon angioplasty enhances nitric oxide (NO) generation and inhibits lesion formation in animals. OBJECTIVES:The present study assessed the effect of increasing NO to inhibit restenosis after percutaneous transluminal coronary angioplasty (PTCA) in hum...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2004-07-01 00:00:00
abstract:BACKGROUND:There is an ongoing debate regarding optimal management of patients with paradoxical low gradient severe aortic stenosis (PLG-SAS). We hypothesized that the presence of symptoms is closely associated with future adverse outcome. We aimed to determine the relation between symptoms and outcome in patients with...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2018.12.017
更新日期:2019-06-01 00:00:00
abstract::The usefulness of electrophysiologic study and Holter monitoring for predicting the long-term efficacy of amiodarone was investigated in 31 patients with sustained ventricular tachycardia (VT) and organic heart disease. Patients underwent both electrophysiologic study and Holter monitoring before and during oral admin...
journal_title:Journal of cardiology
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-11-01 00:00:00
abstract::Slow flow or no-reflow is a serious complication during percutaneous coronary intervention (PCI), but little is known about the risk factors. A 64-year-old man underwent coronary angiography and PCI for stable angina. Pre-interventional intravascular ultrasound demonstrated an ultrasound attenuated coronary plaque, as...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2007-04-01 00:00:00
abstract:BACKGROUND:Along with the global aging, the number of geriatric patients with acute myocardial infarction (AMI) has been increasing. However, temporal trends in the prevalence and outcomes of geriatric patients with AMI, with a special reference to heart failure (HF) on admission, remain to be elucidated. METHODS:The ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2019.10.006
更新日期:2020-05-01 00:00:00
abstract::To assess tricuspid regurgitation (TR) in patients with permanent transvenous right ventricular (RV) pacing, we performed phonocardiographic, contrast and pulsed Doppler echocardiographic studies in 18 patients with transvenous leads for RV pacing. In addition, a pathological study was performed on 26 autopsy cases wi...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1987-06-01 00:00:00
abstract::Ischemic preconditioning is an attenuation of myocardial ischemia by repeated brief coronary occlusions observed during percutaneous transluminal coronary angioplasty (PTCA). The effects of the time delay between balloon inflations during PTCA on ischemic preconditioning were investigated in 48 patients with chronic s...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract::To determine right (RV) and left ventricular (LV) volumes, a new technique was developed using ECG-gated single-photon emission computed tomography (SPECT). RV volumes of nine patients and LV volumes of 22 patients measured by SPECT and biplane contrast cineangiography were compared. In addition, volume and ejection f...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1987-06-01 00:00:00
abstract:OBJECTIVES:Only a few examinations are available to critically ill patients. We assessed the efficacy of transesophageal echocardiography (TEE) in the management of patients with cardiac arrest or shock. METHODS:Among a total of 2,021 patients who underwent TEE over the past 13 years at our institution, we reviewed 18...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2004-11-01 00:00:00
abstract::To elucidate the circumstances involving sudden death, deaths among 20,685 male employees of "K" company during a six-year period from April 1981 to March 1987 were reviewed. The subject age ranged from 19 through 59 years, and averaged 38.6 years. Information concerning each death was obtained from the death reports ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::To evaluate right ventricular (RV) function in severe left ventricular (LV) failure, we measured RV and LV ejection fractions (EF) in 18 patients with old myocardial infarction (OMI) and in 18 with dilated cardiomyopathy (DCM) using cardiac blood pool scintigraphy. In patients with OMI, RVEF was significantly greater ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1987-12-01 00:00:00
abstract::The effects of elective percutaneous transluminal coronary angioplasty (PTCA) performed one month after coronary reperfusion therapy in patients with acute myocardial infarction (AMI) were observed using exercise Tl-201 myocardial scintigraphy performed before and after PTCA. Myocardial perfusion in Tl-201 scintigraph...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Chronic renal disease (CKD) is a determinant of coronary artery calcification (CAC), which is a predictor of cardiovascular events. However, in a population without CKD, the association between CAC and renal function is unclear. CAC is affected by sex. This study aimed to determine whether serum cystatin C, ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2017.05.001
更新日期:2017-12-01 00:00:00