Influence of radiation therapy on reconstructive flaps after radical resection of head and neck cancer.

Abstract:

:This study was undertaken to evaluate the influence of radiotherapy (RT) on reconstructive flaps after radical excision of head and neck cancer. Eighty-eight reconstructive flaps were used in 82 patients who received RT either before (PREOP group, 14 flaps) or after (POSTOP group, 74 flaps) surgery. The success and healing rates of the flaps were evaluated. The success and healing rates were lower in the PREOP group than in the POSTOP group (86% vs 99%, P=0.026 for success; and 64% vs 95%, P=0.003 for healing). The rate of acute radiation reaction in flaps in the POSTOP group was significantly lower than in the surrounding normal tissues (35% vs 84%, P=0.003). Late side effects of RT were rare. Our results suggest good radiation tolerance of reconstructive flaps after radical tumour excision in the head and neck region. Success and healing of the flap are likely to be better if RT is administered after surgery.

authors

Wang Z,Qiu W,Mendenhall WM

doi

10.1054/ijom.2002.0320

subject

Has Abstract

pub_date

2003-02-01 00:00:00

pages

35-8

issue

1

eissn

0901-5027

issn

1399-0020

pii

S0901-5027(02)90320-6

journal_volume

32

pub_type

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