[Solitary and multiple chorangiomas--clinical consequences, expression of growth factors and differences in the growth rate].

Abstract:

BACKGROUND:Chorangiomas are regarded as hamartous lesions of the placenta which may complicate a pregnancy if they grow large. The etiology of these lesion is still unclear. We suspected a link between the development of chorangiomas and an increase of the expression of the angiogenic growth factor bfgf and angiopoietin-1 within the tumour. MATERIAL AND METHODS:We examined 20 placentas without tumour, 19 placentas with solitary chorangiomas and 10 placentas with multiple chorangiomas (chorangiomatosis) with respect of the difference in clinical complications, regarding the expression of bfgf and angiopoietin-1 and with regard to the proliferation rate. RESULTS:The expression of the growth factors in solitary chorangiomas did not differ from that in the normal placental tissue. Both groups showed moderate expression of growth factors. In placentas with multiple chorangiomas all cases were associated with a strong expression of bfgf and angiopoietin-1. Proliferating cells and fibroblasts were seen more often in placentas with chorangiomatosis. There were clinical differences with regard to the maternal age. The mean age in case of normal placentas was 24 years, in placentas with solitary chorangiomas 32 years and for placentas with multiple chorangiomas 28 years. There were more complications such as HELLP-syndrome, diabetes, preterm birth and additional maturational arrest of the placenta in case of chorangiomas. CONCLUSION:There is a link between the development of multiple chorangiomas and an increase of the expression of bfgf and angiopoietin-1 in the placenta. In our study there is no correlation between multiple tumours and complications of pregnancy.

authors

Guschmann M

doi

10.1055/s-2003-37838

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

6-11

issue

1

eissn

0948-2393

issn

1439-1651

journal_volume

207

pub_type

杂志文章
  • Intrapartum ST segment analyses (STAN) using simultaneous invasive and non-invasive fetal electrocardiography: a report of 6 cases.

    abstract::The objective of this study was to analyze ST segment analyses (STAN) using simultaneous traditional - gold standard invasive (fetal scalp electrode) and newly available non-invasive abdominal fetal electrocardiography (fECG) during delivery.This was a prospective observational study of non-invasive fetal ECG using 5 ...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-0034-1375606

    authors: Reinhard J,Hayes-Gill B,Yuan J,Schiermeier S,Louwen F

    更新日期:2014-06-01 00:00:00

  • [Severe autoimmune thrombocytopenia in pregnancy].

    abstract::Maternal thrombocytopenia is a frequent finding in pregnancy. The clinically important causes of maternal thrombocytopenia in pregnancy are gestational thrombocytopenia and autoimmune thrombocytopenia. We report a case of refractory idiopathic thrombocytopenic purpura by a 30-year-old pregnant woman, gravida 3, para 2...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:

    authors: Widmer A,Brühwiler H,Krause M,Lüscher KP

    更新日期:1999-11-01 00:00:00

  • [An unusual course of fetal gastroschisis].

    abstract::We report on prenatal diagnosis of gastroschisis at 20th gestational week. In addition to gastroschisis intraabdominal intestinal stenosis was detected. As a consequence cesarean section was planned close to term. Control examinations in the last trimester didn't confirm initial diagnosis so that the recommended mode ...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:

    authors: Wilhelm C,Prömpeler H,Rädecke J,Krüger M,Breckwoldt M

    更新日期:1998-03-01 00:00:00

  • [Intrauterine growth retardation--perinatal mortality and postnatal morbidity in a perinatal center].

    abstract:OBJECTIVES:The intrauterine growth retardation (IUGR) contributes specially to perinatal mortality and morbidity. An effective treatment is not yet available. The purpose of this study is to analyse the perinatal data of a cohort with IUGR-infants including mortality and morbidity and to describe prematurity and IUGR a...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-2000-9581

    authors: Meyberg R,Boos R,Babajan A,Ertan AK,Schmidt W

    更新日期:2000-11-01 00:00:00

  • [Fetal monitoring intra partum with cardiotocography and fetal blood sampling analysis and its possible influence on the C-section rate].

    abstract::In times of rising c-section rates worldwide the obstetricians feel a big responsibility in avoiding a secondary c-section for non-reassuring fetal heart rate. No other experimental method has been established beside the gold standard (cardiotocography and fetal blood sampling) in daily routine until today. The two ca...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-2004-818961

    authors: Butterwegge M

    更新日期:2004-04-01 00:00:00

  • [Prevention of preterm birth by Shirodkar cerclage--clinical results of a retrospective analysis].

    abstract::In spite of the continuous progress in prenatal care, 1 out of 10 babies is born too early--tendency rising worldwide. As a consequence of the heterogeneous aetiology of preterm birth, there is still no single and efficient interventional therapy. Cerclage is one option for pregnancies with cervical insufficiency, whe...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章,多中心研究

    doi:10.1055/s-0034-1382070

    authors: Schubert RA,Schleussner E,Hoffmann J,Fiedler A,Stepan H,Gottschlich A

    更新日期:2014-08-01 00:00:00

  • [Bilateral renal agenesis in insulin-dependent maternal diabetes mellitus (IDDM)--a case report].

    abstract::We report a fetal bilateral renal agenesis in a woman suffering from insulin-dependent diabetes mellitus. Early diagnosis of this lethal congenital anomaly allows well-timed termination of pregnancy. Transvaginal sonography in combination with color flow mapping render possible an accurate diagnosis of bilateral renal...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:

    authors: Ruhland F,Ohlinger R,Radmann D,Heinrich J

    更新日期:1998-11-01 00:00:00

  • [Interdisciplinary treatment of early-onset ornithine transcarbamylase (OTC) deficiency. Two case reports and a review].

    abstract:PATIENT REPORTS:We report on a male preterm infant (gestational age 31 weeks, birth weight 1420 g) and a male term infant (gestational age 38 weeks, birth weight 3680 g) with ornithine transcarbamylase (OTC) deficiency. After inconspicuous cardiopulmonary adjustment, both entered a state of metabolic crisis with respir...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-2001-19056

    authors: Hübler A,Seidel J,Patzer L,Bellstedt K,Schramm D

    更新日期:2001-11-01 00:00:00

  • [The lactobacilli-protection system of pregnant women--efficient prevention of premature births by early detection of disturbances].

    abstract:BACKGROUND:The most frequent cause of preventable early premature births (< 32 + 0 gestational weeks) is urogenital tract infection (UTI). Screening for UTI and Chlamydia are now standard examinations. Detection of ascending genital infections, especially bacterial vaginosis, plays an ever-increasing role. Lactobacilli...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-2005-871305

    authors: Saling E,Schreiber M

    更新日期:2005-08-01 00:00:00

  • [Changes in umbilical cord blood acid-base status after delivery in dependence on time intervall--a continuing forensic problem].

    abstract:BACKGROUND:The time window for measuring blood gases in the umbilical cord after birth is often discussed controversial with regard to birth damage claims. METHODS:53 umbilical cords from spontaneous deliveries at term were double clamped at room temperature directly after birth and paired arterial and venous samples ...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-0032-1323794

    authors: Butterwegge M,Kappen R,Rath W

    更新日期:2012-12-01 00:00:00

  • [Removal of a broken silastic catheter with a "snare"-catheter in a neonate].

    abstract::Silastic central catheters inserted peripherally are used in neonatology since more than 20 years. Typical complications include catheter associated infection, thrombosis and malposition. Pericardial effusion, fracture and embolisation are rare. We report the case of a female newborn with congenital diaphragmatic hern...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-2007-960543

    authors: Haase R,Lieser U,Nagel F,Syska J

    更新日期:2007-02-01 00:00:00

  • [Incarceration of the Gravid Uterus in the Second Trimester - Diagnostics, Successful Therapy and Review of Literature].

    abstract::A rare complication in obstetrics is the incarceration of the gravid uterus. If the uterus remains retroverted, the fundus persists in the pelvic cavity. Due to growth, the familiar anatomy of the uterus changes and undetected incarceration can lead to a serious maternal morbidity. Early treatment can enable a normal ...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/a-1285-8338

    authors: Hüner B,Handke-Vesely A,Janni W,Reister F

    更新日期:2020-11-12 00:00:00

  • [Breech presentation - more than just caesarean vs. spontaneous birth].

    abstract::The cesarean section rate and the associated complications are still rising in Germany. An important indication is term breech in singletons. Not significant data concerning a higher morbidity or mortality in vaginal breech birth indicate the cesarean but a deficit in education and experience. ...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-0032-1309052

    authors: Louwen F,Leuchter LM,Reitter A

    更新日期:2012-08-01 00:00:00

  • [Angiogenic factors and their role in pathogenesis and prediction of preeclampsia].

    abstract::Angiogenic factors like placental growth factor (PlGF) and its anti-angiogenic antagonists soluble fms-like tyrosine kinase 1 (sFlt1) and soluble endoglin (sEng) are closely related to the pathogenesis of preeclampsia and intrauterine growth restriction (IUGR). The discovery and investigation of these angiogenic facto...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0029-1224142

    authors: Stepan H,Jank A

    更新日期:2009-06-01 00:00:00

  • [Delivery following surgically treated sacrococcygeal teratoma in the mother].

    abstract::The delivery of a 23 para I who was born herself with a sacrococcygeal teratoma of the type II is reported. After the extirpation of the tumor and of the coccyx an anomaly of the pelvis is found in the sense of a pygopagic pelvis (stretching and bending of the sacrum towards the dorsum). This anomaly and the scars in ...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:

    authors: Kohlberger P,Helbich T,Schaller A

    更新日期:1997-07-01 00:00:00

  • [Longitudinal study of 24-hour blood pressure behavior in pregnancy and puerperium in patients with normal pregnancy, pre-eclampsia and HELLP syndrome].

    abstract::Ante- and postpartum noninvasive 24-hour ambulatory blood pressure measurements were performed in 18 normotensive pregnants and 36 patients with mild (n = 16) or severe preeclampsia (n = 12) or HELLP-syndrome (n = 8). In contrast to normotensive pregnancy (n = 18) displaying a decline of systolic and diastolic blood p...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:

    authors: Ruschitzka F,Schulz E,Kling H,Schrader J,Rath W

    更新日期:1996-05-01 00:00:00

  • [Case report of 39-Year-Old Gravida III, Para III with Inverted Uterus after Breech Birth].

    abstract::An inverted uterus is defined as the eversion of the uterus into the vagina. It is a very rare event but has to be treated as an emergency. A woman with an inverted uterus is in serious danger of developing atony with high blood loss in a short time. This can lead to hypovolemic shock and circulatory failure. Therapy ...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/a-0828-8696

    authors: Findeklee S

    更新日期:2020-02-01 00:00:00

  • Overview Tumour Disease and Oncologic Therapy During Pregnancy.

    abstract::Newly diagnosed cancer in pregnancy is an issue with increasing importance, because fulfilling the wish to have a child is shifted later in life. Tumour disease is diagnosed in around 0.1% of all pregnancies in Germany. Most common tumour entities involve the breast, the cervix and the hematopoietic system. As tumour ...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0044-100259

    authors: Findeklee S

    更新日期:2018-04-01 00:00:00

  • [Psychosocial child development after successful infertility treatment].

    abstract::The long-term development of children after assisted reproduction, especially the physical, mental and social development, has attracted increasing interest. Most studies are focused on singletons after ART compared to those after spontaneous conception. A distinction is made between health, cognitive and psychosocial...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-0033-1347206

    authors: Kowalcek I

    更新日期:2013-06-01 00:00:00

  • Zum Beitrag: Frühgeburtenrate in 6 Perinatalzentren in Baden-Württemberg – Potenzial zur Reduktion der Frühgeborenenzahl.

    abstract::Frühgeburtenrate in 6 Perinatalzentren in Baden-Württemberg – Potential zur Reduktion der Frühgeborenenzahl Sehr geehrte Damen und Herren,mit großem Interesse haben wir die Arbeit von Trotter et al. 1 gelesen und teilen die Auffassung, dass eine Vermeidung von Frühgeburten und eine Reduzierung der Frühgeburtenrate unb...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/a-0950-6770

    authors: Rossi R,Heller G,Maier RF

    更新日期:2019-08-01 00:00:00

  • [Progressive systemic sclerosis and pregnancy].

    abstract::Progressive systemic sclerosis is a connective tissue disease with inflammation and fibrosis. Pregnant women with progressive systemic sclerosis have an increased risk for preterm births and probably for small-for-date babies. We report the case of a 28-year-old II G O P suffering from progressive systemic sclerosis w...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-2005-916247

    authors: Brinckmann A,Broermann L,Heidenreich W

    更新日期:2005-12-01 00:00:00

  • [Pregnant Women with Gestational Diabetes in Berlin - An Analysis of Perinatal Data Especially Regarding Immigration Background].

    abstract::To date there has not been a systematic analysis of pregnant patients with an immigrant background and gestational diabetes in Germany, even though the number of these patients has been rising continuously since the 1980s. METHODS:The case number estimate for this prospective study targeted 160 patients with gestatio...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/a-1270-8258

    authors: Hees KA,Podkaminskij S,Breckenkamp J,Borde T,Klapp C,Henrich W,David M

    更新日期:2020-11-02 00:00:00

  • [Periodontal diseases--a review on the association between maternal periodontitis and adverse pregnancy outcome].

    abstract::Several prospective clinical trials have indicated an association between maternal periodontal status and adverse pregnancy outcome, e.g., low birth weight, pre-term birth and pre-eclampsia. However, the translation of these findings into clinical care and decision making is still a matter of debate. Gynecologists and...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0034-1385859

    authors: Manegold-Brauer G,Hoesli I,Brauer HU,Beikler T

    更新日期:2014-12-01 00:00:00

  • [Lipoma of the corpus callosum in a newborn infant: misinterpretation of cranial ultrasound by coincidence with thrombocytopenia].

    abstract::Among the very rare intracerebral lipomas, those of the corpus callosum are the most frequent. Due to the advanced technology and the frequent use of ultrasonography these lesions are diagnosed more and more often. A female neonate was admitted to our hospital because of a progressive thrombocytopenia. Pregnancy was c...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:

    authors: Abou Lebdi KJ,Kentrup H,Reul J,Alzen G,Heimann G

    更新日期:1998-09-01 00:00:00

  • Geburtshilfliche Notfälle – eine neue Serie zum Neuen Jahr.

    abstract::Liebe Leserinnen und Leser,vielleicht befinden Sie sich in der Ausbildung zum Facharzt für Gynäkologie und Geburtshilfe oder erinnern sich noch gut daran. Ein großer Anteil der Weiterbildung findet in einer Klinik statt, und man fürchtet den ersten Dienst. Man steht am Kreißbett und ist stets respektvoll gespannt, geb...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/a-0734-4708

    authors: de Sousa MT

    更新日期:2018-12-01 00:00:00

  • [Ear acupuncture points in newborn triplets].

    abstract::The current study demonstrates for the first time the presence of ear acupuncture points in prematurely delivered triplets of 31 weeks and two days gestational age. Pregnancy was an IVF pregnancy and caesarean section was performed because of preeclampsia. Ear acupuncture points were determined with the Svesa point se...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-2007-960676

    authors: Stähler van Amerongen K,Kuhn A,Surbek D,Nelle M

    更新日期:2007-04-01 00:00:00

  • [Complicating neonatal Escherichia coli meningitis].

    abstract::Neonatal Escherichia coli meningitis is a serious disease with high mortality and poor outcome. Ventriculitis, brain abscess and subdural empyema are frequent, with no homogeneous recommendations available for these complications. The case of a newborn infant who developed sepsis and meningitis caused by E. coli is p...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-2004-815521

    authors: Sonntag J,Kaczmarek D,Brinkmann G,Kammler G,Hellwege HH

    更新日期:2004-02-01 00:00:00

  • [Hodgkin's disease in pregnancy--case report and literature review].

    abstract::We report the case of a 24-year-old Gravida II/Para I who was diagnosed with Hodgkin's disease (stage 2A) at week 28 of pregnancy. Due to clinical progression, a dose-reduced adriamycin, bleomycin, vincristin, dacarbazine chemotherapy was started at week 32. After unsuccessful induction of labor at week 35, secondary ...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-2003-39153

    authors: Schäffer M,Hegenbart U,Klostermann K,Stepan H

    更新日期:2003-03-01 00:00:00

  • [Can subpartal fetal acidosis be avoided? Investigations on the complex causes of intrauterine asphyxia].

    abstract:OBJECTIVE:The extent to which faulty medical treatment and defective apparatus are concomitant causes for the development of subpartal acidosis was investigated in a retrospective study. At the same time, the incidence of acidosis in the Lippe-Detmold Hospital, Department of Gynaecology and Obstetrics, its morbidity an...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章

    doi:10.1055/s-2002-34962

    authors: Roemer VM,Mähling B

    更新日期:2002-09-01 00:00:00

  • [H1N1--pregnancy as risk factor].

    abstract::There have been repeated reports of a particularly severe course of disease on H1N1 infection in pregnant women. Complemented by a review of the current literature, this paper gives an overview of recommendations with respect to vaccination, therapy and prophylaxis in this risk group. ...

    journal_title:Zeitschrift fur Geburtshilfe und Neonatologie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0030-1251973

    authors: Landt S,Sina F,Kimmig R,Schmidt M

    更新日期:2010-04-01 00:00:00