Effect of CO(2) pneumoperitoneum on ventilation-perfusion relationships during laparoscopic cholecystectomy.

Abstract:

BACKGROUND:Previous studies have shown that pneumoperitoneum transiently reduces venous admixture as assessed by a calculation based on the shunt formula, and increases arterial oxygen tension (PaO(2)) in patients without heart or lung disease. The aim of the present study was to further explore the relationship between ventilation-perfusion (V(A)/Q) before and during pneumoperitoneum by using the multiple inert gas technique. METHODS:Nine patients without heart or lung disease (ASA I), with a mean age of 42 years, scheduled for laparoscopic cholecystectomy were included. After premedication and induction of anaesthesia, radial artery and pulmonary artery catheters were introduced percutaneously. The V(A)Q relationships were evaluated by the multiple inert gas elimination technique before and during pneumoperitoneum to obtain a direct measure of the pulmonary shunt. RESULTS:Induction of pneumoperitoneum decreased the pulmonary shunt from 5.8 (4.5) to 4.1 (3.2)% (P<0.05) and increased PaO(2) from 21.7 (5.9) to 24.7 (4.8) kPa (P<0.01). During surgery, the shunt increased from 3.2 (2.8) to 5.2 (3.4)% to the same level as before pneumoperitoneum induction. No area with low V(A)Q was seen. Dead space ventilation amounted to 20.0 (1.2)% in the supine position and did not change during the investigation. CONCLUSIONS:In patients without heart or lung disease, pneumoperitoneum at an intra-abdominal pressure level of 11-13 mmHg causes a transient reduction of the pulmonary shunt. The mechanisms underlying the present finding remain to be elucidated.

authors

Andersson L,Lagerstrand L,Thörne A,Sollevi A,Brodin LA,Odeberg-Wernerman S

doi

10.1034/j.1399-6576.2002.460513.x

subject

Has Abstract

pub_date

2002-05-01 00:00:00

pages

552-60

issue

5

eissn

0001-5172

issn

1399-6576

pii

aas460513

journal_volume

46

pub_type

临床试验,杂志文章
  • From intracranial pressure to intracranial pressure wave-guided intensive care management of a patient with an aneurysmal subarachnoid haemorrhage.

    abstract::We report on a 65-year-old female with an aneurysmal subarachnoid hemorrhage (SAH) that was followed clinically, radiologically and electrophysiologically before and after converting from intracranial pressure (ICP)-guided to ICP wave-guided intensive care management. Intracranial pressure-guided management is aimed a...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.2007.01269.x

    authors: Eide PK,Sorteberg W,Meling T,Jörum E,Hald J,Stubhaug A

    更新日期:2007-04-01 00:00:00

  • Anaesthetic-induced cardioprotection in an experimental model of the Takotsubo syndrome - isoflurane vs. propofol.

    abstract:BACKGROUND:Takotsubo syndrome (TS) is an acute cardiac condition with a substantial mortality for which no specific treatment is available. We have previously shown that isoflurane attenuates the development of left ventricular (LV) dysfunction in an experimental TS-model. We compared the effects of equi-anaesthetic do...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aas.12857

    authors: Oras J,Redfors B,Ali A,Lundgren J,Sihlbom C,Thorsell A,Seeman-Lodding H,Omerovic E,Ricksten SE

    更新日期:2017-03-01 00:00:00

  • MAC for halothane and isoflurane during normothermia and hypothermia in the newborn piglet.

    abstract:BACKGROUND:Halothane and isoflurane are frequently used in studies of perinatal hypoxia and ischemia. Little information exists on the minimum alveolar concentration (MAC) necessary to prevent movement to a painful stimulus in newborn pigs and no information on the effects of hypothermia on MAC in pigs. Hypothermia is ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1996.tb04468.x

    authors: Satas S,Haaland K,Thoresen M,Steen PA

    更新日期:1996-04-01 00:00:00

  • Cervical epidural steroid injection for cervicobrachialgia.

    abstract::Fifty patients with chronic resistant cervicobrachialgia were randomly divided into two groups. Twenty-five patients (group A) were treated with cervical epidural steroid/lidocaine injections and 17 patients (group B) were treated with steroid/lidocaine injections into the posterior neck muscles. Another eight patient...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1399-6576.1993.tb03765.x

    authors: Stav A,Ovadia L,Sternberg A,Kaadan M,Weksler N

    更新日期:1993-08-01 00:00:00

  • Epidural versus combined spinal epidural block for cesarean section.

    abstract::In a controlled study a single segment combined spinal epidural (CSE) block was compared with epidural block for cesarean section. Thirty healthy parturients were randomly divided into two groups. In both groups a T4 block was aimed at. Bupivacaine was used to provide analgesia in both groups. All patients receiving C...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1399-6576.1988.tb02689.x

    authors: Rawal N,Schollin J,Wesström G

    更新日期:1988-01-01 00:00:00

  • Determination of 'recruited volume' following a PEEP step is not a measure of lung recruitability.

    abstract:BACKGROUND:It has been proposed that the analysis of positive end-expiratory pressure (PEEP)-induced volume changes can quantify alveolar recruitment. The potential of a lung to be recruited is expected to be high in acute respiratory distress syndrome (ARDS), where collapsed lung tissue is very common. The volume chan...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aas.12432

    authors: Stahl CA,Möller K,Steinmann D,Henzler D,Lundin S,Stenqvist O

    更新日期:2015-01-01 00:00:00

  • Anaesthesiological airway management in Denmark: assessment, equipment and documentation.

    abstract:BACKGROUND:Failed intubation remains one cause of anaesthesia-related morbidity and mortality. In a recent survey in Denmark, 20% of respondents reported preventable mishaps in airway management. METHODS:Assessment of the airway, and its documentation, as well as the availability of various equipment to manage a diffi...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.0001-5172.2004.0337.x

    authors: Mellado PF,Thunedborg LP,Swiatek F,Kristensen MS

    更新日期:2004-03-01 00:00:00

  • Mathematical model of renal elimination of fluid and small ions during hyper- and hypovolemic conditions.

    abstract::This study is concerned with the formulation of a 'kidney module' linked to the plasma compartment of a larger mathematical model previously developed. Combined, these models can be used to predict, amongst other things, fluid and small ion excretion rates by the kidney; information that should prove useful in evaluat...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1399-6576.2003.00037.x

    authors: Gyenge CC,Bowen BD,Reed RK,Bert JL

    更新日期:2003-02-01 00:00:00

  • Piritramide and alfentanil display similar respiratory depressant potency.

    abstract:BACKGROUND:The question whether some opioids exert less respiratory depression than others has not been answered conclusively. We applied pharmacokinetic/pharmacodynamic (PKPD) modeling to obtain an estimate of the C50 for the depression of CO2 elimination as a measure of the respiratory depressant potency of alfentani...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1046/j.1399-6576.2003.00251.x

    authors: Bouillon T,Garstka G,Stafforst D,Shafer S,Schwilden H,Hoeft A

    更新日期:2003-11-01 00:00:00

  • Ear injury caused by elevated intratympanic pressure during general anaesthesia.

    abstract::Two cases of middle-ear injury, due to sharp fluctuations of intratympanic pressure as a result of general anaesthesia with nitrous oxide are presented. A study is reported indicating that the degree of these fluctuations is a function of the concentration of nitrous oxide. In order to reduce the risk of middle-ear in...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1980.tb01539.x

    authors: Man A,Segal S,Ezra S

    更新日期:1980-06-01 00:00:00

  • Hypertensive response to thiopental in man during cardiopulmonary bypass.

    abstract::We report the effect of 250 mg of sodium thiopental on vascular tone at constant blood flow in 26 patients undergoing cardiopulmonary bypass while the ascending aorta was cross-clamped. Light anaesthesia was effected with fentanyl and enflurane, muscle relaxation with pancuronium. After a latent period of 10.5 +/- 0.7...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1986.tb02475.x

    authors: Pauca AL,Roy RC

    更新日期:1986-10-01 00:00:00

  • Opioid use in cancer pain. Is a more liberal approach enhancing toxicity?

    abstract::The majority of cancer patients develop pain before death. This pain has been shown to be underdiagnosed and undertreated. Opioid use has increased in the past 20 years in both developing and developed countries. The changing pattern in opioid use has resulted in the emergence of neurotoxicity as a major side effect o...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1034/j.1399-6576.1999.430910.x

    authors: Daeninck PJ,Bruera E

    更新日期:1999-10-01 00:00:00

  • Comparison of fentanyl and halothane as supplement to nitrous-oxide-oxygen anaesthesia for coronary artery surgery.

    abstract::Twenty unselected patients suffering from incapacitating angina, in spite of medication with nitrates, beta-blockers and calcium antagonists, were studied before and during coronary artery bypass surgery. Fentanyl or halothane was randomly used in combination with nitrous oxide for maintenance of anaesthesia in order ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1399-6576.1985.tb02152.x

    authors: Fischerström A,Ohqvist G,Settergren G

    更新日期:1985-01-01 00:00:00

  • Platelet gel and fibrin sealant reduce allogeneic blood transfusions in total knee arthroplasty.

    abstract:BACKGROUND:Total knee arthroplasty (TKA) is often associated with a considerable amount of post-operative blood loss, necessitating the transfusion of allogeneic blood, which can add to the complications. Optimization of strategies to reduce the need for blood transfusion is desired. This study was designed to evaluate...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1399-6576.2006.001005.x

    authors: Everts PA,Devilee RJ,Brown Mahoney C,Eeftinck-Schattenkerk M,Box HA,Knape JT,van Zundert A

    更新日期:2006-05-01 00:00:00

  • Contributions of myocardial ischemia and heart rate to ST segment changes in patients with or without coronary artery disease.

    abstract:BACKGROUND:ST changes related to ischemia at different heart rates (HRs) have not been well described. We aimed to analyze ST dynamic changes by vectorcardiography (VCG) during pacing-induced HR changes for subjects with proven coronary artery disease (CAD) and without (non-CAD). METHODS:Symptomatic CAD patients sched...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.2007.01507.x

    authors: Häggmark S,Haney MF,Johansson G,Reiz S,Näslund U

    更新日期:2008-02-01 00:00:00

  • Comparison of two prehospital predictive models for mortality and impaired consciousness after severe traumatic brain injury.

    abstract:BACKGROUND:The primary aim was to investigate the performance of a National Advisory Committee for Aeronautics based predictive model (NACA-BM) for mortality at 14 days and a reference model using motor GCS (GCS-RM). The secondary aim was to compare the models for impaired consciousness of survivors at 14 days (IC-14; ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aas.13229

    authors: Pannatier M,Delhumeau C,Walder B

    更新日期:2019-01-01 00:00:00

  • Effects of high thoracic epidural anaesthesia on the peripheral airway reactivity in dogs.

    abstract:BACKGROUND:It has been speculated that epidural anaesthesia may induce bronchoconstriction via the mechanism of a sympathetic blockade. However, this hypothesis has not been confirmed by any experimental evidence. Therefore, we investigated the effects of high thoracic epidural anaesthesia with neural sympathetic block...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1998.tb05085.x

    authors: Yuan HB,Tang GJ,Kou YR,Lee TY

    更新日期:1998-01-01 00:00:00

  • A case of suspected non-neurosurgical adult fatal propofol infusion syndrome.

    abstract::A previously healthy woman (20 years old) was admitted to our hospital with several fractures after a car accident. She was sedated with propofol, etc. in doses ranging from 1.4 to 5.1 mg/kg/h for 88 h. She developed multiple organ failure with rhabdomyolysis and died. This case fulfils (except acidosis) the criteria ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.2006.00904.x

    authors: Eriksen J,Povey HM

    更新日期:2006-01-01 00:00:00

  • Thoracic epidural analgesia via the lumbar approach using nerve stimulation in a pediatric patient with Down syndrome.

    abstract::This case illustrates the threading of an epidural catheter with electrical stimulation guidance from the lumbar epidural space to the thoracic space in a pediatric patient. A 17-year-old boy with Down syndrome, weighing 48 kg, was scheduled to undergo a laparotomy for duodenal obstruction and gastrostomy tube inserti...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.2005.00684.x

    authors: Tsui BC,Entwistle L

    更新日期:2005-05-01 00:00:00

  • Bilateral eye hemorrhage after laparoscopic cholecystectomy.

    abstract::A case of bilateral eye hemorrhage after laparoscopic cholecystectomy, probably caused by an increase in venous blood pressure due to carbon dioxide insufflation, is reported. ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1399-6576.2001.450821.x

    authors: Calenda E,Muraine M,Zerzour H,Sambo B,Siahmed K

    更新日期:2001-09-01 00:00:00

  • Comparison of parenteral diclofenac and ketoprofen for postoperative pain relief after maxillofacial surgery.

    abstract::Non-steroidal anti-inflammatory drugs (NSAID) effectively reduce the need for opioid analgesia after various types of surgery. The efficacy of diclofenac and ketoprofen to relieve pain after maxillofacial surgery was compared in the present study. In a randomized and double-blind fashion, 90 ASA I-II patients (16-60 y...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1399-6576.1995.tb05599.x

    authors: Niemi L,Tuominen M,Pitkänen M,Rosenberg PH

    更新日期:1995-01-01 00:00:00

  • Intraoperative MgSO4 infusion protects oxygenation and lung mechanics in COPD patients during general anesthesia. A randomized clinical trial.

    abstract:BACKGROUND:The purpose of this study was to examine the effects of an intraoperative MgSO4 infusion on arterial oxygenation and lung mechanics in patients with moderate COPD undergoing cancer larynx surgery under general anesthesia (GA). Our primary outcome was arterial oxygenation determined by the PaO2 and PaO2 /FiO2...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aas.13684

    authors: Ahmed A,Sayed AH,Elkholy J,Elshal S,Badwy A,Abdelhamid B,Ollaek M

    更新日期:2020-11-01 00:00:00

  • Non-transport emergency medical service missions - a retrospective study based on medical charts.

    abstract:BACKGROUND:In Finland, approximately 40% of emergency medical service (EMS) missions do not result in transport of the patient to a hospital by ambulance, and there is wide variability in the reasons underlying non-transport decisions. The aim of this study was to describe the context of these EMS non-transport mission...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aas.13071

    authors: Pekanoja S,Hoikka M,Kyngäs H,Elo S

    更新日期:2018-05-01 00:00:00

  • Decisions not to resuscitate in a Swedish university hospital.

    abstract:BACKGROUND:Cardiopulmonary resuscitation (CPR) has the potential to save many lives. Used indiscriminately though, it may be harmful and not in the best interest of the patient. An advance directive to refrain from resuscitation in selected patients is probably not uncommon in Sweden, but guidelines ruling this are sti...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1997.tb04642.x

    authors: Friberg H,Adolfsson A,Lundberg D

    更新日期:1997-11-01 00:00:00

  • Failure to protect against myocardial ischemia-reperfusion injury with sevoflurane postconditioning in old rats in vivo.

    abstract:BACKGROUND:Sevoflurane post-conditioning (SpostC) protects young hearts against ischemia-reperfusion injury. It is unknown whether the infarct-limiting effect is also maintained in aged cohorts and whether there are age-associated differences in the underlying mechanisms. METHODS:Young or old rats were randomly subjec...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aas.12156

    authors: Li H,Zhou C,Chen D,Fang N,Yao Y,Li L

    更新日期:2013-09-01 00:00:00

  • Is development of hyperalgesia, allodynia and myoclonus related to morphine metabolism during long-term administration? Six case histories.

    abstract:BACKGROUND:Recently, clinical reports have suggested a relationship between the occurrence of hyperalgesia, allodynia and/or myoclonus and treatment with high doses of morphine in humans. Although few clinical descriptions of these phenomena are available, experimental work supports the notion that high doses of morphi...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.1998.tb05378.x

    authors: Sjøgren P,Thunedborg LP,Christrup L,Hansen SH,Franks J

    更新日期:1998-10-01 00:00:00

  • Wound infiltration with local anesthetics for post-operative pain relief in lumbar spine surgery: a systematic review.

    abstract:BACKGROUND:In this systematic review, we evaluated double-blind, randomized and controlled trials on the effect of wound infiltration with local anesthetics compared with the effect of placebo on post-operative pain after lumbar spine surgery. METHODS:Medline, the Cochrane Library and Google Scholar were searched for ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/j.1399-6576.2011.02629.x

    authors: Kjærgaard M,Møiniche S,Olsen KS

    更新日期:2012-03-01 00:00:00

  • Intraoperative awareness: detected by the structured Brice interview?

    abstract:BACKGROUND:Awareness is a rare complication in general anesthesia, but its consequences are stressful. Efforts must be undertaken to prevent, diagnose, and, if occurring, treat it. The incidence of awareness is higher following anesthesia involving the use of muscle relaxants. As a part of a quality assurance program a...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1034/j.1399-6576.2002.460402.x

    authors: Enlund M,Hassan HG

    更新日期:2002-04-01 00:00:00

  • Gas embolism: an exceptional complication of radial arterial catheterization.

    abstract:BACKGROUND:We report a rare complication of radial arterial catheterization in a 74-year-old man who had undergone retroperitoneal surgery for an infra-renal aortic aneurysm. A right subclavian venous catheter and a right radial artery catheter were inserted for hemodynamic monitoring. RESULTS:The patient suddenly wen...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.1399-6576.2004.00476.x

    authors: Dube L,Soltner C,Daenen S,Lemarieé J,Asfar P,Alquier P

    更新日期:2004-10-01 00:00:00

  • Vasopressor hormone response following mesenteric traction during major abdominal surgery.

    abstract:BACKGROUND:We investigated the vasopressor hormone response following mesenteric traction (MT) with hypotension due to prostacyclin (PGI2) release in patients undergoing abdominal surgery with a combined general and epidural anesthesia. METHODS:In a prospective, randomized, placebo-controlled study we administered 400...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1399-6576.1998.tb05355.x

    authors: Brinkmann A,Seeling W,Wolf CF,Kneitinger E,Schönberger C,Vogt N,Orend KH,Büchler M,Radermacher P,Georgieff M

    更新日期:1998-09-01 00:00:00