The effect of increased tissue pressure on blood flow.

Abstract:

:Theoretical consideration of the factors involved in maintaining vascular equilibrium and experimental evidence in animals and man indicate that at high tissue pressures there may be a sharp decline in blood flow and, in certain situations, complete cessation of blood flow even at tissue pressures below mean arterial pressure. At least two mechanisms appear to be involved: active closure of small arterioles under vasomotor tone when transmural pressure is lowered, either by falls in intravascular pressure or rises in tissue pressure, and passive collapse of soft-walled capillaries when tissue pressure rises above intracapillary pressure. These mechanisms are likely to assume particular importance when tissues are surrounded by non-compliant fascia and may thus be involved in compartmental syndromes.

journal_name

Clin Orthop Relat Res

authors

Ashton H

doi

10.1097/00003086-197511000-00004

subject

Has Abstract

pub_date

1975-11-01 00:00:00

pages

15-26

issue

113

eissn

0009-921X

issn

1528-1132

pub_type

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