Low-intensity ultrasound stimulation in distraction osteogenesis in rabbits.

Abstract:

:Low-intensity pulsed ultrasound has been shown to accelerate fracture healing. This experiment investigated its possible role in distraction. Thirty-four New Zealand White rabbits had distraction osteogenesis, followed by low-intensity pulsed ultrasound therapy. Seventeen animals had the ultrasound transducer switched off (controls). Four and 6 weeks postoperatively, tibiae were analyzed using quantitative computed tomography and four-point mechanical testing. Two tibiae from each group had histologic analysis at 4 weeks. No significant differences were identified between regenerates of ultrasound-treated and control groups with respect to bone mineral content, cross-sectional area, and strength. No significant reductions in osteopenia proximal and distal to the regenerate were observed. Histologic observation showed no differences in bone volume fraction, but ultrasound-treated regenerates appeared to have fewer trabeculae of increased thickness, and fewer osteoclasts. The modulation by ultrasound may occur by accelerating endochondral ossification through action on chondrocytes, yet distraction osteogenesis is largely intramembranous. Although ultrasound is proven to be effective in unconstrained systems such as plaster, the current study does not support the role of low-intensity pulsed ultrasound as an adjunct for patients having distraction osteogenesis in a rigid fixator. Additional research is needed to definitively support the use of low-intensity pulsed ultrasound in such situations.

journal_name

Clin Orthop Relat Res

authors

Uglow MG,Peat RA,Hile MS,Bilston LE,Smith EJ,Little DG

doi

10.1097/01.blo.0000093043.56370.5a

subject

Has Abstract

pub_date

2003-12-01 00:00:00

pages

303-12

issue

417

eissn

0009-921X

issn

1528-1132

pub_type

杂志文章
  • Femoral Component Varus Malposition is Associated with Tibial Aseptic Loosening After TKA.

    abstract:BACKGROUND:The notion that neutral alignment is mandatory to assure long-term durability after TKA has been based mostly on short-film studies. However, this is challenged by recent long-film studies. QUESTIONS/PURPOSES:We conducted this long-film study to know (1) whether the risk of aseptic revision for nontraumatic...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999.0000000000000012

    authors: Lee BS,Cho HI,Bin SI,Kim JM,Jo BK

    更新日期:2018-02-01 00:00:00

  • Osteoid osteoma of the hip in children.

    abstract::In 31 children with osteoid osteoma lesions about the hip ranging in age from 2 to 16 years, there was an inordinate frequency of diagnostic delay with 16 patients having symptoms for more than 12 months. The clinical features were dominated by pain, limp, restricted hip motion and thigh atrophy. Twelve patients did n...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-197501000-00006

    authors: Goldberg VM,Jacobs B

    更新日期:1975-01-01 00:00:00

  • CT evaluation of coverage and congruency of the hip prior to osteotomy.

    abstract::A computer-assisted model has been developed to improve the results of surgical techniques for reconstruction of hip dysplasia. This method assesses the coverage and congruency of the femoral head by evaluating multiple factors that may influence surgical planning. It achieves a more reliable image because the measure...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Klaue K,Wallin A,Ganz R

    更新日期:1988-07-01 00:00:00

  • Management of neuropathic arthropathy with the Charcot Restraint Orthotic Walker.

    abstract::A recently designed Charcot Restraint Orthotic Walker (CROW) was used in the treatment of 18 patients with diabetic neuroarthropathy involving the foot and ankle. Eight of these patients had no surgery before the use of the CROW. In ten patients, the device was used for prolonged immobilization after surgery for compl...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Morgan JM,Biehl WC 3rd,Wagner FW Jr

    更新日期:1993-11-01 00:00:00

  • The orthopaedist's role in healthcare system governance.

    abstract:BACKGROUND:Historically, physicians as participants in healthcare governance were shunned because of perceived potential for conflict of interest. This maxim is being revisited as health systems begin to appreciate the value presented by physician leaders. QUESTIONS/PURPOSES:This overview of the orthopaedist's role in...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-013-2950-6

    authors: Probe RA

    更新日期:2013-06-01 00:00:00

  • Surgical treatment of knee dysfunction in cerebral palsy.

    abstract::The prerequisites for normal gait are: (1) stability in the stance phase of gait, (2) clearance of the foot in the swing phase, (3) proper foot preposition in swing, and (4) an adequate step length. In the stance phase, the knee provides shock absorption and energy conservation; in the swing phase, it allows foot clea...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Gage JR

    更新日期:1990-04-01 00:00:00

  • The rise of academic orthopaedic surgery during the past 44 years.

    abstract::In accepting this invitation to write a prefatory chapter as a mini professional autobiography, it has become all too obvious that this has touched a few nerve endings that had healed many years ago. Contemplating personal experiences, thoughts, and philosophies and then writing them should have a purpose. During thes...

    journal_title:Clinical orthopaedics and related research

    pub_type: 传,历史文章,杂志文章

    doi:

    authors: Duthie RB

    更新日期:1994-03-01 00:00:00

  • Results of direct exchange or debridement of the infected total knee arthroplasty.

    abstract::In this literature review, 30 reports provided outcome data on 37 direct exchange arthroplasties, 530 open debridements, and 23 arthroscopic debridements. The average followup was approximately 4 years, but the range was broad (range, 0.02-14 years). Infection was controlled in 33 of the 37 infected total knee arthrop...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-200211000-00022

    authors: Silva M,Tharani R,Schmalzried TP

    更新日期:2002-11-01 00:00:00

  • Congenital pseudoarthrosis of the tibia: treatment with pulsing electromagnetic fields.

    abstract::Ninety-two patients with congenital pseudoarthrosis (infantile nonunion) were treated with pulsing electromagnetic fields (PEMF) in the United States and Europe in the past eight years. This represents the largest group of patients with infantile nonunions in which a common treatment modality has been used. Excluding ...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Kort JS,Schink MM,Mitchell SN,Bassett CA

    更新日期:1982-05-01 00:00:00

  • Medical specialty credentialing in the United States.

    abstract::Specialty boards serve the function of defining qualifications and issuing credentials to assure the public of the specialist's preparation and skill. Over the past 72 years, 23 such boards have been approved and now issue 31 different types of general specialty certificates and 57 types of subspecialty credentials. F...

    journal_title:Clinical orthopaedics and related research

    pub_type: 历史文章,杂志文章

    doi:

    authors: Langsley DG

    更新日期:1990-08-01 00:00:00

  • Acetabular preparation in cementless revision total hip arthroplasty.

    abstract::The rationale for and experience with the use of a hemispherical, cementless, microporous socket (Harris-Galante prosthesis) are presented as an approach to acetabular revision arthroplasty. Advantages are noted in preservation of existing bone, ease of rigid fixation, and bone grafting with either lyophylized particl...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: McGann WA,Welch RB,Picetti GD 3rd

    更新日期:1988-10-01 00:00:00

  • Displaced femoral neck fractures in the elderly: outcomes and cost effectiveness.

    abstract::The optimal treatment for displaced femoral neck fractures in elderly patients is a matter of controversy. Four surgical options are well supported in the orthopaedic literature: reduction with internal fixation, unipolar hemiarthroplasty, bipolar hemiarthroplasty, and total hip arthroplasty. Based on a review of the ...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-200102000-00027

    authors: Iorio R,Healy WL,Lemos DW,Appleby D,Lucchesi CA,Saleh KJ

    更新日期:2001-02-01 00:00:00

  • Emerging ideas: can erythromycin reduce the risk of aseptic loosening?

    abstract:BACKGROUND:Persistent inflammatory reaction to wear debris causes periprosthetic osteolysis and loosening. Some authors have advocated pharmaceutical approaches to reduce the inflammatory reaction. Erythromycin has antiinflammatory effects independent of its antimicrobial properties. Although oral erythromycin reported...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-011-1918-7

    authors: Ren W,Markel DC

    更新日期:2011-08-01 00:00:00

  • Magnetic resonance imaging of the shoulder.

    abstract::Magnetic resonance imaging (MRI) is proving to be an effective means for evaluating the shoulder. The use of a surface coil and high resolution scanning techniques have allowed detailed analysis of the normal anatomy of the shoulder. When evaluating for shoulder pathology, the choice of imaging plane and pulse sequenc...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:

    authors: Seeger LL

    更新日期:1989-07-01 00:00:00

  • Dislocation of the hip after reimplantation for infection: an analysis of risk factors.

    abstract::Dislocation is a well documented complication after a two-stage revision arthroplasty for a deep periprosthetic hip infection. We are aware of no reports specifically evaluating the risk factors for dislocation after reimplantation for infection. We hypothesized greater age, increase in the number of operations on the...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/01.blo.0000218747.92118.3a

    authors: Hartman CW,Garvin KL

    更新日期:2006-06-01 00:00:00

  • Transforming growth factor-beta in osteolytic breast cancer bone metastases.

    abstract::Breast cancers frequently metastasize to the skeleton and cause bone destruction. Tumor cells secrete factors that stimulate osteoclasts. The consequent osteolytic resorption releases active factors from the bone matrix, in particular transforming growth factor-beta (TGF-beta). The released factors then stimulate tumo...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:10.1097/01.blo.0000093055.96273.69

    authors: Guise TA,Chirgwin JM

    更新日期:2003-10-01 00:00:00

  • Intralesional curettage for grades II and III giant cell tumors of bone.

    abstract:UNLABELLED:Grade III Campanacci lesions are traditionally treated with wide resections based on their postulated aggressiveness and potential for local recurrence and metastasis. The purpose of this study was to determine if there was a difference in local recurrence rates of Grade II and III lesions treated with intra...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/01.blo.0000180051.27961.c3

    authors: Lackman RD,Hosalkar HS,Ogilvie CM,Torbert JT,Fox EJ

    更新日期:2005-09-01 00:00:00

  • The result of replacement of partial or total collateral ligaments with Marlex mesh in the knees of dogs.

    abstract::Marlex mesh is a synthetic material which has been used clinically to replace ligamentous structures. It serves as a scaffold for infiltration of the fibroblasts eventually becoming mature fibrocytes. In dogs, almost totally mature fibrocytes appear within the framework of the Marlex mesh prosthesis by the end of 3 mo...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Winston LA,Terry AF,Jardine JH,Parrish FF

    更新日期:1978-11-01 00:00:00

  • Resection of the forefoot in rheumatoid arthritis.

    abstract::A long-term review of 272 resections of the metatarsal heads and bases of the phalanges in 128 patients with severe rheumatoid feet is presented. The longest follow-up is 11 years and the average follow-up was 4.7 years. Recurrent deformity and callus formation was usually due to a long metatarsal shaft. The operation...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-197505000-00036

    authors: Marmor L

    更新日期:1975-05-01 00:00:00

  • Acetabular revision with metal mesh, impaction bone grafting, and a cemented cup.

    abstract:UNLABELLED:Impaction grafting is controversial in the presence of segmental and cavitary acetabular defects and requires the use of supplemental devices to close segmental defects. This approach, however, would allow treating combined deficiencies that could not be managed with impacted cancellous bone alone. We raised...

    journal_title:Clinical orthopaedics and related research

    pub_type: 临床试验,杂志文章

    doi:10.1007/s11999-008-0442-x

    authors: Buttaro MA,Comba F,Pusso R,Piccaluga F

    更新日期:2008-10-01 00:00:00

  • Ankle arthrodesis using internal screw fixation.

    abstract::Ankle arthrodesis treated by external fixation frequently results in complications from pin tract infections, loss of position, nonunion, and malunion. A method of ankle arthrodesis using 6.5-mm cancellous screws as the primary fixation hardware was developed. The most important screw is placed from the posterior mall...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Holt ES,Hansen ST,Mayo KA,Sangeorzan BJ

    更新日期:1991-07-01 00:00:00

  • Peripheral nerve complications following burn injury.

    abstract::The involvement of peripheral nerves in burn injury is not common, but when nerves are involved, prompt therapeutic intervention is necessary to avoid increased morbidity. Aside from the direct effects of the trauma, the burn team must anticipate dangerously excessive edema from circumferential burns, and avoid second...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Salisbury RE,Dingeldein GP

    更新日期:1982-03-01 00:00:00

  • Traumatic partial arrest of tibial physis.

    abstract::Two children with premature partial arrest of the tibial physis, one proximal and the other distal, were treated by resection of the bony bar and by the Langenskiold method of interposition of fat. In one child the arrest was the result of an open fracture and bony loss of the upper tibia. In the other child the arres...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Mayer V,Marchisello PJ

    更新日期:1984-03-01 00:00:00

  • Surgical treatment of displaced olecranon fractures by tension band wiring technique.

    abstract::Forty-five displaced olecranon fractures including 14 accompanying dislocated radial heads and seven radial head fractures were treated over a 13-year period by the tension band wiring technique. The use of supplemental internal fixation when necessary allows excellent results with the use of this technique, even in t...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:

    authors: Wolfgang G,Burke F,Bush D,Parenti J,Perry J,LaFollette B,Lillmars S

    更新日期:1987-11-01 00:00:00

  • Spinal infections in patients with compromised immune systems.

    abstract:UNLABELLED:Spinal infections are relatively uncommon but have potentially devastating consequences if not diagnosed and treated correctly. Compromised immunologic responsiveness, either transient or permanent, predisposes patients to more frequent and more severe infections. Through a Medline review of the English-lang...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:10.1097/01.blo.0000201176.87635.f3

    authors: Cunningham ME,Girardi F,Papadopoulos EC,Cammisa FP

    更新日期:2006-03-01 00:00:00

  • Articular cartilage injuries.

    abstract::The acute and repetitive impact and torsional joint loading that occurs during participation in sports can damage articular surfaces causing pain, joint dysfunction, and effusions. In some instances, this articular surface damage leads to progressive joint degeneration. Three classes of chondral and osteochondral inju...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章,评审

    doi:10.1097/00003086-200209000-00004

    authors: Buckwalter JA

    更新日期:2002-09-01 00:00:00

  • Epiphyseal plate involvement in osteosarcoma.

    abstract::Fourteen boys (56%) and 11 girls (44%) 4 to 17 years of age (mean, 12.2 years) who had osteosarcoma and open epiphyseal plates were studied. A possible correlation between transepiphyseal spread of osteosarcoma and radiologic and histopathologic findings was investigated. Epiphyseal plate invasion was detected radiolo...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-200004000-00006

    authors: Jesus-Garcia R,Seixas MT,Costa SR,Petrilli AS,Laredo Filho J

    更新日期:2000-04-01 00:00:00

  • Predictors of transfusion risk in elective knee surgery.

    abstract::Two hundred seventy-nine patients undergoing primary unilateral total knee replacement and 280 patients undergoing primary bilateral total knee replacements were reviewed retrospectively. Patients' height, weight, hemoglobin level before donation, hemoglobin level before surgery, autologous donation, number and type o...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1097/00003086-199812000-00008

    authors: Keating EM,Meding JB,Faris PM,Ritter MA

    更新日期:1998-12-01 00:00:00

  • Stratification of standardized TKA complications and adverse events: a brief communication.

    abstract:BACKGROUND:The Total Knee Arthroplasty (TKA) Complications Workgroup of the Knee Society developed a standardized list and definitions of complications associated with TKA. Twenty-two complications and adverse events believed important for reporting outcomes of TKA were identified. The Editorial Board of Clinical Ortho...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-013-2980-0

    authors: Iorio R,Della Valle CJ,Healy WL,Berend KR,Cushner FD,Dalury DF,Lonner JH

    更新日期:2014-01-01 00:00:00

  • Case report: Quantitative MRI of tibial tubercle transfer during active quadriceps contraction.

    abstract:BACKGROUND:The evaluation of distal transfer procedures relies primarily on qualitative clinical findings. Although quantitative MRI measurements provide an objective supplement to qualitative clinical findings, an association between qualitative clinical findings and quantitative patellofemoral indices has yet to be e...

    journal_title:Clinical orthopaedics and related research

    pub_type: 杂志文章

    doi:10.1007/s11999-010-1598-8

    authors: Duchman K,Mellecker C,El-Hattab AY,Albright JP

    更新日期:2011-01-01 00:00:00