Therapies on the horizon for cholesterol reduction.

abstract：:Hospitals typically use Center for Medicare and Medicaid Services' (CMS) Hospital Readmission Reduction Program (HRRP) administrative reports as the standard of heart failure (HF) admission quantification. We aimed to evaluate the HF admission population identified by CMS HRRP definition of HF hospital admissions comp...

journal_title：Clinical cardiology

authors： Cox ZL,Lai P,Lewis CM,Lenihan DJ

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Isolated left ventricular abnormal trabeculation (ILVAT) is defined as > 3 coarse trabeculations of the left ventricular wall, apically to the papillary muscles, in hearts without congenital malformations. HYPOTHESIS:The aims of the study were to assess by echocardiography the prevalence of ILVAT, to confir...

journal_title：Clinical cardiology

authors： Stöllberger C,Finsterer J,Valentin A,Blazek G,Tscholakoff D

更新日期：1999-02-01 00:00:00

abstract：:The effects of monotherapy with atenolol or diltiazem-SR on blood pressure, 24-h blood pressure (BP) load, and exercise capacity were tested in patients with mild to moderate (stages I and II) essential hypertension. After 3-week single-blind placebo therapy, patients with sitting diastolic blood pressure (SDBP) of 94...

journal_title：Clinical cardiology

authors： Chrysant SG,Miller E

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:There is increasing evidence that chronic atrial fibrillation (AF) is associated with a prothrombotic or hypercoagulable state. HYPOTHESIS:This study was undertaken to determine whether short-term exercise in patients with chronic AF would shift the overall hemostatic balance toward a more prothrombotic sta...

journal_title：Clinical cardiology

authors： Li-Saw-Hee FL,Blann AD,Edmunds E,Gibbs CR,Lip GY

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Massive evidence supports that increase of lipids bring more risk of atherosclerosis. However, it is not clear if lipids measured a long time ago bear more risk than the current measurement. HYPOTHESIS:Lipids measured currently is more associated with carotid atherosclerosis than lipids measured long time a...

journal_title：Clinical cardiology

authors： Huang Y,Yu X,Millican D,Wu L,Shi P,Lu M,Wu Y

更新日期：2012-08-01 00:00:00

abstract：:The importance of a history of angina pectoris on long-term timolol treatment after myocardial infarction was studied with respect to mortality and reinfarction. The analyses were performed retrospectively using cohorts from the Norwegian timolol multicenter study. In patients without angina pectoris prior to the infa...

journal_title：Clinical cardiology

authors： Gundersen T,Kjekshus J

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:Fluoroscopy has been an essential part of every electrophysiological procedure since its inception. However, till now no clear standards regarding acceptable x-ray exposure nor recommendation how to achieve them have been proposed. HYPOTHESIS:Current norms and quality markers required for optimal clinical r...

journal_title：Clinical cardiology

authors： Kosiuk J,Fiedler L,Ernst S,Duncker D,Pavlović N,Guarguagli S,Stegmann C,Miskowiec D,Garcia R,Russo V,Yakushev A,Szegedi N,De Potter T

更新日期：2021-01-01 00:00:00

abstract：:The Randomized Endo-vein Graft Prospective (REGROUP) trial (ClinicalTrials.gov NCT01850082) is a randomized, intent-to-treat, 2-arm, parallel-design, multicenter study funded by the Cooperative Studies Program (CSP No. 588) of the US Department of Veterans Affairs. Cardiac surgeons at 16 Veterans Affairs (VA) medical ...

journal_title：Clinical cardiology

authors： Zenati MA,Gaziano JM,Collins JF,Biswas K,Gabany JM,Quin JA,Bitondo JM,Bakaeen FG,Kelly RF,Shroyer AL,Bhatt DL

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Atherosclerotic cardiovascular disease is prevalent among renal transplant patients. Increase in serum total cholesterol, low-density lipoprotein, and very low-density lipoprotein is common in those patients. Alterations in chylomicron metabolism, however, are also related to atherogenesis and were not studi...

journal_title：Clinical cardiology

authors： De Lima JJ,Latrilha Mda C,Toffoletto O,Ianhez LE,Krieger EM,Maranhão RC

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:The efficacy of prophylactic coronary revascularization with percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) surgery in patients with abdominal aortic aneurysm (AAA) scheduled for open repair surgery remains controversial. HYPOTHESIS:Concomitant coronary artery disease (CAD) ...

journal_title：Clinical cardiology

authors： Hosokawa Y,Takano H,Aoki A,Inami T,Ogano M,Kobayashi N,Tanabe J,Yokoyama H,Kato T,Takagi H,Umemoto T,Takayama M,Mizuno K

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Syncope is a common clinical problem with a variety of underlying mechanisms, some of which occur more frequently in 1 of the sexes or at a certain age. HYPOTHESIS:There may be clinically significant age- and gender-related differences in patients with unexplained syncope. METHODS:Five hundred seventy pati...

journal_title：Clinical cardiology

authors： Edvardsson N,Garutti C,Rieger G,Linker NJ,PICTURE Study Investigators.

更新日期：2014-10-01 00:00:00

abstract：:Women's health and well-being are shaped by a combination of healthcare policies that impact the type of health insurance coverage they benefit from, as well as access to preventive, screening, and treatment services. Furthermore, more distal policies, such as those that pertain to housing, education, and employment, ...

journal_title：Clinical cardiology

authors： Brindis CD,Freund KM

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Therapeutic hypothermia improves survival for selected patients who remain comatose after cardiac arrest. Hypothermia triggers changes in electrocardiographic (ECG) parameters; however, the association of these changes to in-hospital mortality remains unclear. HYPOTHESIS:QT interval changes induced by thera...

journal_title：Clinical cardiology

authors： Lam DH,Dhingra R,Conley SM,Kono AT

更新日期：2014-02-01 00:00:00

abstract：:The treatment of hypertension continues to be challenging due to the lack of understanding regarding underlying modulators of blood pressure as well as co-existing conditions such as atherosclerosis and diabetes. This has led to uncertainty regarding treatment strategy and intensity. The INternational VErapamil SR/tra...

journal_title：Clinical cardiology

authors： Kolloch RE

更新日期：2001-11-01 00:00:00

abstract：:Hypertrophic cardiomyopathy predisposes patients to atrial fibrillation and the development of systemic embolization. We describe a rare case of bilateral renal artery thrombosis which presented as acute renal failure requiring dialysis. The patient was successfully treated with a selective, continuous infusion of uro...

journal_title：Clinical cardiology

authors： Fu GY,Candela RJ,Mishkind M,Obarski T,Yakubov SJ

更新日期：1994-11-01 00:00:00

abstract：:Pulmonary hypertension comprises a family of disorders occurring as a primary disease or as a complication of a large number of respiratory and cardiac diseases. Pulmonary hypertension is present when pulmonary artery pressure or mean pressure exceeds 30 mmHg or 20 mmHg, respectively. Underlying the hemodynamic change...

journal_title：Clinical cardiology

authors： Moraes D,Loscalzo J

更新日期：1997-08-01 00:00:00

abstract：:Cross-sectional echocardiography was performed on two patients with mitral regurgitation in whom M-mode echocardiographic findings were not specific for the etiology of mitral regurgitation. In one patient, flail motion of the free edge of the anterior mitral leaflet into the left atrium was demonstrated only by cross...

journal_title：Clinical cardiology

authors： Ogawa S,Mardelli TJ,Hubbard FE

更新日期：1978-08-01 00:00:00

abstract：:Heart transplantation is the only curative therapy for chronic heart failure, and it plays an important role in the treatment of chronic heart failure with a survival rate of approximately 50% of all patients after 10 years. This has to be kept in mind when alternative therapies enter into our daily routine in treatin...

journal_title：Clinical cardiology

authors： Garbade J,Barten MJ,Bittner HB,Mohr FW

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Little is known about the relationship of body fluid status with the levels and fluctuations of B-type natriuretic peptide (BNP) over the long-term. HYPOTHESIS:If BNP is to become useful for monitoring of patients with chronic heart failure (HF), the levels should reliably reflect both decompensation and im...

journal_title：Clinical cardiology

authors： Kataoka H

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Low levels of high-density lipoprotein cholesterol (HDL-C; <40 mg/dL) are associated with increased risk of cardiovascular events, but it is unclear whether lower thresholds (<30 mg/dL) are associated with increased hazard. HYPOTHESIS:Very low levels of HDL-C may provide prognostic information in acute coro...

journal_title：Clinical cardiology

authors： Hagström E,Roe MT,Hafley G,Neely ML,Sidhu MS,Winters KJ,Prabhakaran D,White HD,Armstrong PW,Fox KA,Ohman EM,Boden WE,TRILOGY ACS Investigators.

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Total serum transforming growth factor-beta 1 (tsTGF-β1) is increased in patients with Marfan syndrome (MFS), but it has not been assessed in thoracic aortic aneurysm and dissection (TAAD), Loeys-Dietz syndrome (LDS), and bicuspid aortic valve disease (BAVD). HYPOTHESIS:tsTGF-β1 is increased in genetic aort...

journal_title：Clinical cardiology

authors： Hillebrand M,Millot N,Sheikhzadeh S,Rybczynski M,Gerth S,Kölbel T,Keyser B,Kutsche K,Robinson PN,Berger J,Mir TS,Zeller T,Blankenberg S,von Kodolitsch Y,Goldmann B

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Although ischemic threshold reportedly is lower in the early morning than in the afternoon, the mechanisms that account for the diurnal change in minimal coronary vascular resistance in the potentially ischemic area are unknown. HYPOTHESIS:We hypothesized that calcium-channel blockers and alpha 1 blockers m...

journal_title：Clinical cardiology

authors： Fujita M,Tanaka T,Nakae I,Tamaki S,Kihara Y,Nohara R,Sasayama S

更新日期：1998-05-01 00:00:00

abstract：:The case of a 73-year-old man with right heart failure and systolic and diastolic murmur at the fourth left intercostal space is described. There was a history of rheumatic fever. Two-dimensional echocardiography showed rheumatic change of the tricuspid valve with giant right atrium and ventricle, which was confirmed ...

journal_title：Clinical cardiology

authors： Fujii S,Funaki K,Denzumi N

更新日期：1986-07-01 00:00:00

abstract：:Rapid assessment of patients presenting with acute chest pain is essential, in order to distinguish between those who have a life-threatening condition, such as myocardial infarction or unstable angina, and the substantial proportion who do not have an acute coronary syndrome. It is thus of vital importance that relia...

journal_title：Clinical cardiology

authors： Husted SE

更新日期：2000-01-01 00:00:00

abstract：:Two cases with acute myocardial infarction are presented. Both had thrombotic occlusion of the infarct-related artery. Following successful thrombolysis with streptokinase, coronary angiography was normal. These cases prove that "myocardial infarction with normal coronaries" can be associated with coronary thrombosis ...

journal_title：Clinical cardiology

authors： Fernandez MS,Pichard AD,Marchant E,Lindsay J Jr

更新日期：1983-11-01 00:00:00

abstract：:Several investigators have documented the successful use of oral sustained-release theophylline in treating symptomatic bradycardia and sick sinus syndrome. This paper reports a case of chronotropic incompetence in which specific exercise indices, including the chronotropic response index, were used to measure the the...

journal_title：Clinical cardiology

authors： Dixon WC 4th,Bauch TD

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Current National Cholesterol Education Program (NCEP) guidelines recognize low-density lipoprotein cholesterol (LDL-C) below 100 mg/dl as an optimal level. Evidence supporting this is scant. Both LDL-C and C reactive protein (CRP) are known correlates of atherosclerosis progression. HYPOTHESIS:We examined t...

journal_title：Clinical cardiology

authors： Kent SM,Coyle LC,Flaherty PJ,Markwood TT,Taylor AJ

更新日期：2004-01-01 00:00:00

abstract：:Angioplasty in patients with unstable coronary artery disease is associated with higher complication rates compared with patients with stable disease. In this report we describe our results from a group of patients with unstable disease (unstable angina pectoris and postmyocardial infarction) where a strategy of delay...

journal_title：Clinical cardiology

authors： Rozenman Y,Gilon D,Zelingher J,Sapoznikov D,Lotan C,Mosseri M,Weiss AT,Hasin Y,Gotsman MS

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Inflammatory process plays an important role in the pathogenesis of acute coronary syndromes. HYPOTHESIS:The study was undertaken to evaluate whether admission levels of C-reactive protein (CRP), fibrinogen, interleukin-6 (IL-6). and macrophage colony stimulating factor (MCSF) can predict short-term prognos...

journal_title：Clinical cardiology

authors： Rallidis LS,Zolindaki MG,Manioudaki HS,Laoutaris NP,Velissaridou AH,Papasteriadis EG

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Inflammation is a key factor in the development of atherosclerotic disease and acute coronary syndromes (ACS). The P2Y(12) receptor antagonists ticagrelor (AZD6140) and clopidogrel may have anti-inflammatory effects. The objective of this analysis from the Dose Confirmation Study Assessing Anti-Platelet Effe...

journal_title：Clinical cardiology

authors： Husted S,Storey RF,Harrington RA,Emanuelsson H,Cannon CP

更新日期：2010-04-01 00:00:00