Effects of gabapentin in acute inflammatory pain in humans.

abstract：BACKGROUND AND OBJECTIVES:Stellate ganglion block (SGB) is one treatment option for human trigeminal nerve injury. The aim of this study was to evaluate the effectiveness of cervical sympathetic ganglia blocks (SB) by comparing the recovery of severed nerves in 2 rat models, treated or not treated by SB. METHODS:The i...

journal_title：Regional anesthesia and pain medicine

authors： Hanamatsu N,Yamashiro M,Sumitomo M,Furuya H

更新日期：2002-05-01 00:00:00

abstract：:Perioperative outcomes research has gained widespread interest and is viewed as increasingly important among different specialties, including anesthesiology. Outcomes research studies serve to help in the adjustment of risk, allocation of resources, and formulation of hypotheses to guide future research. Pursuing high...

journal_title：Regional anesthesia and pain medicine

authors： Memtsoudis SG,Mazumdar M,Stundner O,Hargett MJ

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The acetylcholinesterase inhibitor neostigmine has shown peripherally mediated analgesic action in recent preclinical and clinical studies. The present study investigates the effectiveness of adding neostigmine to a local anesthetic, mepivacaine, in patients receiving axillary brachial plexus ...

journal_title：Regional anesthesia and pain medicine

authors： Bone HG,Van Aken H,Booke M,Bürkle H

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Peripherally administered opioids, e.g., intra-articular morphine, exert their analgesic action on local opioid receptors. The present study investigated the safety and efficacy of intrabursal oxycodone and bupivacaine in comparison with bupivacaine infiltration and interscalene brachial plexu...

journal_title：Regional anesthesia and pain medicine

authors： Muittari P,Kirvelä O

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Chronic pain is both prevalent and costly. Despite advances in understanding the anatomy, physiology, and biochemistry of nociception and development of potent analgesic agents and advanced technology, a significant number of people continue to experience pain and related disability. The perce...

journal_title：Regional anesthesia and pain medicine

authors： Turk DC

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Previously, we have demonstrated that extending a continuous femoral nerve block (cFNB) from overnight to 4 days after total knee arthroplasty (TKA) provides clear benefits during the infusion, but not subsequent to catheter removal. However, there were major limitations in generalizing the results of that i...

journal_title：Regional anesthesia and pain medicine

authors： Ilfeld BM,Shuster JJ,Theriaque DW,Mariano ER,Girard PJ,Loland VJ,Meyer S,Donovan JF,Pugh GA,Le LT,Sessler DI,Ball ST

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The study goal was to compare the effect of epinephrine in different doses on pulmonary gas exchange in a rat model of bupivacaine-induced cardiac depression. METHODS:Twenty-four adult male Sprague-Dawley rats were divided into 4 groups (n = 6), and each group received a bupivacaine infusion (...

journal_title：Regional anesthesia and pain medicine

authors： Wang QG,Wu C,Xia Y,Dong JJ,Lin TT,Liu QY,Papadimos TJ,Xu XZ

更新日期：2017-05-01 00:00:00

abstract：:High-dose opioid administration is associated with significant adverse events. Evidence suggests that low-dose ketamine infusions improve perioperative analgesia over conventional opioid management, but usage is highly variable. Ketamine's adverse drug effects (ADEs) are well known, but their prevalence during low-dos...

journal_title：Regional anesthesia and pain medicine

authors： Schwenk ES,Goldberg SF,Patel RD,Zhou J,Adams DR,Baratta JL,Viscusi ER,Epstein RH

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Accurate needle control during ultrasound (US)-guided nerve blocks may be an elusive goal for the anesthesiologist. Despite modifications to increase echogenicity, needle visibility still requires precise alignment within the transducer beam. In this study, we evaluated a magnetically guided u...

journal_title：Regional anesthesia and pain medicine

authors： Swenson JD,Klingler KR,Pace NL,Davis JJ,Loose EC

更新日期：2016-05-01 00:00:00

abstract：:In March of 2010, President Barack Obama signed into law the Patient Protection and Affordable Care Act, ushering in an era of health care reform. Section 6002 of the bill, the Physician Payment Sunshine Act, requires manufacturers of drugs, devices, biological therapeutics, and medical supplies to disclose to the Cen...

journal_title：Regional anesthesia and pain medicine

authors： Dickerson DM,Naidu RK

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:The majority of intrathecal pumps are implanted by anesthesiologists. Despite a recent increase in case reports involving intrathecal catheter-tip inflammatory masses, this complication is rarely reported in the anesthesiology literature. The present case report describes a patient with spinal cord compressi...

journal_title：Regional anesthesia and pain medicine

authors： Peng P,Massicotte EM

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Gabapentin is an anticonvulsant that has been shown to be effective in the treatment of neuropathic and inflammatory pain in animal and human studies. The analgesic effect of its perioperative use has not been fully elucidated. METHODS:This systematic review (meta-analysis) included 12 random...

journal_title：Regional anesthesia and pain medicine

authors： Hurley RW,Cohen SP,Williams KA,Rowlingson AJ,Wu CL

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Ultrasound-guided regional anesthesia is a rapidly growing field. There exists little information regarding the competencies involved with such a practice. The objective of this exploratory study was to characterize the behavior of novices as they undertook the challenges of learning a new tec...

journal_title：Regional anesthesia and pain medicine

authors： Sites BD,Spence BC,Gallagher JD,Wiley CW,Bertrand ML,Blike GT

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Epidural catheters are seldom difficult to remove from patients. In fact, a review of the literature demonstrates only a few cases pertaining to epidurals and the unusual complication of catheter entrapment. METHODS:This case report involves an uncomplicated obstetric patient who had an epidu...

journal_title：Regional anesthesia and pain medicine

authors： Jongleux EF,Miller R,Freeman A

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Quadratus lumborum (QL) block is a new regional analgesic technique for upper and lower abdominal surgeries as part of a multimodal analgesic regime. It has also been reported to relieve pain after total hip arthroplasty (THA). In this prospective, randomized, double-blind study, we compared Q...

journal_title：Regional anesthesia and pain medicine

authors： Kukreja P,MacBeth L,Sturdivant A,Morgan CJ,Ghanem E,Kalagara H,Chan VWS

更新日期：2019-10-25 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Practitioners mix faster-onset, intermediate-duration local anesthetics (LAs) with slower-onset, long-duration LAs to get fast peripheral nerve block (PNB) onset and long duration. We hypothesized that 1.5% mepivacaine (with epinephrine) (mepivacaine) or 1.5% mepivacaine (with epinephrine) mix...

journal_title：Regional anesthesia and pain medicine

authors： Laur JJ,Bayman EO,Foldes PJ,Rosenquist RW

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Arthroscopic anterior cruciate ligament (ACL) reconstruction of the knee is a painful procedure requiring intensive postoperative pain management. This prospective study investigates analgesic quality after a femoral block as compared with intra-articular injection of local anesthetic. METHOD...

journal_title：Regional anesthesia and pain medicine

authors： Iskandar H,Benard A,Ruel-Raymond J,Cochard G,Manaud B

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Prior to this investigation, there was no approach to compare both the potency of local anesthetics and their time course of action in a reproducible nociceptive system in humans. We tested whether the vascularly isolated vein segment is appropriate for such an approach. METHODS:In six health...

journal_title：Regional anesthesia and pain medicine

authors： Holthusen H,Lipfert P,Klement W

更新日期：1999-07-01 00:00:00

abstract：:The introduction of ultrasound guidance for regional anesthesia has resulted in an explosion of interest in its use for postoperative analgesia, particularly for orthopedic surgery. Regional anesthesia demonstrates unequivocal superiority compared with systemic opioids with respect to analgesia, reduced opioid consump...

journal_title：Regional anesthesia and pain medicine

authors： Choi S,Trang A,McCartney CJ

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Whether patients titrate themselves to an individualized blood or plasma opioid concentration (the so-called minimum effective concentration or [MEC]) has been debated extensively. Nevertheless, there is consistent opinion that during patient controlled analgesia (PCA) patients balance accepta...

journal_title：Regional anesthesia and pain medicine

authors： Woodhouse A,Mather LE

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Percutaneous peripheral nerve stimulation (PNS) is an analgesic modality involving the insertion of a lead through an introducing needle followed by the delivery of electric current. This modality has been reported to treat chronic pain as well as postoperative pain the day following knee surg...

journal_title：Regional anesthesia and pain medicine

authors： Ilfeld BM,Gabriel RA,Said ET,Monahan AM,Sztain JF,Abramson WB,Khatibi B,Finneran JJ 4th,Jaeger PT,Schwartz AK,Ahmed SS

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Epidural anesthesia (EA) is known to reduce postoperative thromboembolic complications, but mechanisms are incompletely understood. In this study, we tested the hypothesis that local anesthetics (LA) prevent postoperative hypercoagulability without affecting physiologic aggregation and coagula...

journal_title：Regional anesthesia and pain medicine

authors： Hollmann MW,Wieczorek KS,Smart M,Durieux ME

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Anesthesia and analgesia with paravertebral block are reportedly variable. Existence of an endothoracic fascia has been proposed as one of the possible mechanisms leading to variability. We undertook an electron-microscopy imaging study to investigate the endothoracic fascia in the thoracic pa...

journal_title：Regional anesthesia and pain medicine

authors： Stopar Pintaric T,Veranic P,Hadzic A,Karmakar M,Cvetko E

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Lipid infusion reverses systemic local anesthetic toxicity. The acceptable upper limit for lipid administration is unknown and has direct bearing on clinical management. We hypothesize that high volumes of lipid could have undesirable effects and sought to identify the dose required to kill 50% of the animal...

journal_title：Regional anesthesia and pain medicine

authors： Hiller DB,Di Gregorio G,Kelly K,Ripper R,Edelman L,Boumendjel R,Drasner K,Weinberg GL

更新日期：2010-03-01 00:00:00

abstract：:This article qualitatively assesses and summarizes randomized, controlled studies regarding benefits of ultrasound (US) for brachial plexus block and also examines those studies that have compared different brachial plexus block techniques using US.Studies were identified by a search of PUBMED and EMBASE databases usi...

journal_title：Regional anesthesia and pain medicine

authors： McCartney CJ,Lin L,Shastri U

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We hypothesized that ultrasound-guided wrist blocks may be faster to perform, and may increase success rate, compared with nerve stimulation-guided wrist blocks. METHODS:Sixty patients undergoing ambulatory endoscopic carpal tunnel release were randomly allocated to receive median and ulnar n...

journal_title：Regional anesthesia and pain medicine

authors： Macaire P,Singelyn F,Narchi P,Paqueron X

更新日期：2008-07-01 00:00:00

abstract：:The blood-brain barrier (BBB) describes the unique properties of endothelial cells (ECs) that line the central nervous system (CNS) microvasculature. The BBB supports CNS homeostasis via EC-associated transport of ions, nutrients, proteins and waste products between the brain and blood. These transport mechanisms also...

journal_title：Regional anesthesia and pain medicine

authors： Viscusi ER,Viscusi AR

更新日期：2020-09-01 00:00:00

abstract：:Despite a growing awareness about the importance of gender equity and the rising number of women in medicine, women remain persistently underrepresented in pain medicine and anesthesiology. Pain medicine ranks among the bottom quartile of medical specialties in terms of female applicants, female trainees, and proporti...

journal_title：Regional anesthesia and pain medicine

authors： Doshi TL,Bicket MC

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:0.1% bupivacaine for obstetric epidural analgesia is given by infusion, using a loading dose of a higher concentration alone or in combination with opioid analgesics. A single dose of 0.1% without any additive for relief of first-stage labor pain has not yet been documented. METHODS:Fifty-eig...

journal_title：Regional anesthesia and pain medicine

authors： Christiaens F,Verborgh C,Dierick A,Camu F

更新日期：1998-03-01 00:00:00

abstract：:Shoulder surgery is associated with significant postoperative pain in many patients. The use of an interscalene nerve block offers good analgesia but is associated with a high incidence of an ipsilateral phrenic nerve block. Several strategies to avoid this adverse effect have been studied. Possible strategies are (1)...

journal_title：Regional anesthesia and pain medicine

authors： Verelst P,van Zundert A

更新日期：2013-01-01 00:00:00