Blood-brain barrier: mechanisms governing permeability and interaction with peripherally acting μ-opioid receptor antagonists.

abstract：:The Accreditation Council for Graduate Medical Education has shifted to competency-based medical education. This educational framework requires the description of educational outcomes based on the knowledge, skills and behaviors expected of competent trainees. It also requires an assessment program to provide formativ...

journal_title：Regional anesthesia and pain medicine

authors： Woodworth G,Maniker RB,Spofford CM,Ivie R,Lunden NI,Machi AT,Elkassabany NM,Gritsenko K,Kukreja P,Vlassakov K,Tedore T,Schroeder K,Missair A,Herrick M,Shepler J,Wilson EH,Horn JL,Barrington M

更新日期：2020-08-01 00:00:00

abstract：:Abrupt cessation of intrathecal baclofen (ITB) administration can cause a life-threatening withdrawal syndrome that requires prompt diagnosis and urgent treatment. The current therapy for this condition is administration of propofol, benzodiazepines, paralytics and supportive care. This study reports a 53-year-old pat...

journal_title：Regional anesthesia and pain medicine

authors： Bellinger A,Siriwetchadarak R,Rosenquist R,Greenlee JD

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The transversus abdominis plane (TAP) block can be used as part of a multimodal analgesia protocol after abdominal surgery. This study investigated whether a pneumoperitoneum during abdominal surgery influences the spread of local anesthetics. METHODS:Nine fresh frozen cadavers were used for ...

journal_title：Regional anesthesia and pain medicine

authors： Desmet M,Helsloot D,Vereecke E,Missant C,van de Velde M

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:We report a case of perioperative management of a single-ventricle patient with Fontan-associated liver disease undergoing hepatectomy. CASE REPORT:A 12-year-old boy with Fontan circulation was scheduled for partial hepatectomy to remove a liver mass in segment 6. He received stent implantation to relieve co...

journal_title：Regional anesthesia and pain medicine

authors： Maeda A,Shibata SC,Okitsu K,Imada T,Takahashi A,Uchiyama A,Kamibayashi T,Fujino Y

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this study is to examine the effects of head-up tilt (70 degrees ) 30 minutes after right or left stellate ganglion block (SGB) on RR interval, QT interval, the rate-corrected QT (QTc) interval, QT dispersion (QTD), and the rate-corrected QT dispersion (QTcD) using computerized meas...

journal_title：Regional anesthesia and pain medicine

authors： Fujii K,Yamaguchi S,Egawa H,Hamaguchi S,Kitajima T,Minami J

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Third occipital nerve block (TONB) is commonly used in the diagnosis and treatment of upper neck pain and cervicogenic headaches. Although fluoroscopy is the current imaging standard for TONB, ultrasound (US) guidance offers a promising, radiation-free alternative. In this randomized, observer-blinded trial,...

journal_title：Regional anesthesia and pain medicine

authors： Finlayson RJ,Etheridge JP,Vieira L,Gupta G,Tran DQ

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We present 2 case reports that illustrate that chronic intrathecal (IT) baclofen administration may be efficacious in treating patients with long-standing complex regional pain syndrome, type I (CRPS I) who have failed treatment with multiple drugs and procedures. CASE REPORTS:Both cases pres...

journal_title：Regional anesthesia and pain medicine

authors： Zuniga RE,Perera S,Abram SE

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Success in performing ultrasound-guided peripheral nerve blockade (PNB) demands sound knowledge of sonoanatomy, good scanning techniques, and proper hand-eye coordination. The objectives of our study were to evaluate whether simulator training aids success of novice operators in ultrasound-gui...

journal_title：Regional anesthesia and pain medicine

authors： Niazi AU,Haldipur N,Prasad AG,Chan VW

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Multimodal analgesic clinical pathways for joint replacement patients often include perineural catheters, but long-term adherence to these pathways has not yet been investigated. Our primary aim was to determine adherence rate to a knee arthroplasty clinical pathway for patients undergoing sta...

journal_title：Regional anesthesia and pain medicine

authors： Steckelberg RC,Funck N,Kim TE,Walters TL,Lochbaum GM,Memtsoudis SG,Giori NJ,Indelli PF,Graham LJ,Mariano ER

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Continuous brachial plexus blocks at the interscalene level are associated with known diaphragm dysfunction from phrenic nerve paresis. More distal blocks along the brachial plexus may provide postsurgical analgesia while potentially having less effect on diaphragm function. Continuous intersc...

journal_title：Regional anesthesia and pain medicine

authors： Auyong DB,Yuan SC,Choi DS,Pahang JA,Slee AE,Hanson NA

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Arthroscopic anterior cruciate ligament (ACL) reconstruction of the knee is a painful procedure requiring intensive postoperative pain management. This prospective study investigates analgesic quality after a femoral block as compared with intra-articular injection of local anesthetic. METHOD...

journal_title：Regional anesthesia and pain medicine

authors： Iskandar H,Benard A,Ruel-Raymond J,Cochard G,Manaud B

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We describe a new therapeutic modality for sacroiliac joint syndrome that represents an alternative to other treatment modalities. We report on four cases of sacroiliac joint syndrome with severe pain. METHODS:Three patients had undergone operative treatment of the lumbar spine and one patien...

journal_title：Regional anesthesia and pain medicine

authors： Srejic U,Calvillo O,Kabakibou K

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We hypothesized that ultrasound-guided wrist blocks may be faster to perform, and may increase success rate, compared with nerve stimulation-guided wrist blocks. METHODS:Sixty patients undergoing ambulatory endoscopic carpal tunnel release were randomly allocated to receive median and ulnar n...

journal_title：Regional anesthesia and pain medicine

authors： Macaire P,Singelyn F,Narchi P,Paqueron X

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The current intensity at which a motor response is elicited with an intraneural needle placement has been inadequately studied. We hypothesized that electrical current delivered through an intraneurally placed needle does not always result in an evoked motor response. Our secondary objective w...

journal_title：Regional anesthesia and pain medicine

authors： Tsai TP,Vuckovic I,Dilberovic F,Obhodzas M,Kapur E,Divanovic KA,Hadzic A

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:No study has compared cervical interlaminar epidural steroid injection (CIESI) with epidural catheter advancement to the side and level of pathology versus standard C7-T1 CIESI. This study investigated whether cervical radicular pain is more effectively treated by CIESI with a targeted epidura...

journal_title：Regional anesthesia and pain medicine

authors： McCormick ZL,Nelson A,Bhave M,Zhukalin M,Kendall M,McCarthy RJ,Khan D,Nagpal G,Walega DR

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:This study aimed to describe and assess the accuracy and feasibility of a novel technique for ultrasound-guided maxillary nerve block using the lateral pterygoid plate (LPP) approach via the pterygopalatine fossa (PPF) in a soft cadaveric model. METHODS:Ten soft cadavers were studied. The cur...

journal_title：Regional anesthesia and pain medicine

authors： Kampitak W,Tansatit T,Shibata Y

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Cluster headache is an uncommon debilitating condition for which effective management remains a challenge. We describe the use of gabapentin in the treatment and prophylaxis of cluster headache in a patient who was refractory to other treatments. CASE REPORT:A 38-year-old man had a history of...

journal_title：Regional anesthesia and pain medicine

authors： Tay BA,Ngan Kee WD,Chung DC

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:The ideal spread of local anesthetic for effective, rapid, and safe sciatic nerve block is debated. We hypothesized that subparaneural ultrasound-guided injection results in faster onset and has a better success rate than extraneural circumferential spread. METHODS:Patients undergoing elective tibial, foot,...

journal_title：Regional anesthesia and pain medicine

authors： Choquet O,Noble GB,Abbal B,Morau D,Bringuier S,Capdevila X

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The incidence of postdural puncture headache (PDPH) after epidural wet tap for obstetric patients may be as high as 75%. We have studied how subsequent placement of a subarachnoid catheter immediately after confirmation of a wet tap, and leaving the catheter in place for 24 hours affects the i...

journal_title：Regional anesthesia and pain medicine

authors： Ayad S,Demian Y,Narouze SN,Tetzlaff JE

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Ischemic preconditioning of tissue that is to undergo procedure-induced underperfusion has been used in a number of surgical settings to reduce the subsequent inflammatory response and its sequelae. The objective of this prospective, randomized study was to evaluate the effect of ischemic prec...

journal_title：Regional anesthesia and pain medicine

authors： Memtsoudis SG,Valle AG,Jules-Elysse K,Poultsides L,Reid S,Starcher B,Ma Y,Sculco TP

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Hematoma is typically cited as one mechanism of nerve injury following axillary block. However, documented cases of this are lacking. METHODS:A healthy 38-year-old man was scheduled for surgical removal of a tumor of the hand. A transarterial axillary block was performed with a 22-gauge short...

journal_title：Regional anesthesia and pain medicine

authors： Ben-David B,Stahl S

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVE:Our objective was to describe the first reported use of an axillary brachial plexus block to treat the entrapment of a transradial artery catheter due to vasospasm. CASE REPORT:A 42-year-old man undergoing transradial arterial cardiac catheterization suffered arterial vasospasm causing the catheter to become...

journal_title：Regional anesthesia and pain medicine

authors： Fitzgerald BM,Babbel LA,Bacomo FK,Dhanjal ST

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Epinephrine, 25 microg and 200 microg, has been found to prolong the duration of intrathecal labor analgesia when added to an opioid. In our hospital we use the standard epidural mixture, prepared by the pharmacist, containing epinephrine 1:800,000; i.e., 1.25 microg/mL for both spinal and epi...

journal_title：Regional anesthesia and pain medicine

authors： Vercauteren MP,Jacobs S,Jacquemyn Y,Adriaensen HA

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Because of the uncertainty and limitations in available randomized controlled trials, we performed an analysis of the Medicare claims database to determine whether an association exists between postoperative epidural analgesia and mortality. METHODS:A 5% nationally random sample of Medicare beneficiaries fr...

journal_title：Regional anesthesia and pain medicine

authors： Wu CL,Hurley RW,Anderson GF,Herbert R,Rowlingson AJ,Fleisher LA

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Bupivacaine is a racemic mixture of S(-)- and R(+)-enantiomers. Both isomers have similar potency as local anesthetics, but the S(-)-enantiomer produces less central nervous system and cardiovascular toxicity. Local anesthetic-induced convulsion is likely to be associated with not only sodium ...

journal_title：Regional anesthesia and pain medicine

authors： Ueta K,Sugimoto M,Suzuki T,Uchida I,Mashimo T

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:This study examined whether perioperative multimodal analgesia (MMA) improves the effectiveness of intravenous nutrition (IVN) as a means of preventing protein wasting following major upper abdominal surgery (UAS). The MMA regimen utilized combined epidural opioid/local anesthetic and the syst...

journal_title：Regional anesthesia and pain medicine

authors： Barratt SM,Smith RC,Kee AJ,Mather LE,Cousins MJ

更新日期：2002-01-01 00:00:00

abstract：:The past century has seen immense progress in the advancement of methodology to evaluate efficacy of treatment interventions for acute and chronic pain. Continuing challenges revolve around how to best select and measure primary efficacy outcomes for a given analgesic trial. Recognizing the complex, multidimensional, ...

journal_title：Regional anesthesia and pain medicine

authors： Gilron I,Jensen MP

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND/IMPORTANCE:Ultrasound (US)-guided cervical selective nerve root injections (CSNRI) have been proposed as an alternative to fluoroscopic (FL) -guided injections. When choosing US guidance, the proceduralist should be aware of potential issues confirming vertebral level, be clear regarding terminology, and up ...

journal_title：Regional anesthesia and pain medicine

authors： Ehsanian R,Schneider BJ,Kennedy DJ,Koshkin E

更新日期：2021-01-13 00:00:00

abstract：:Although interscalene brachial plexus block (ISB) remains the gold standard for analgesia after shoulder surgery, the inherent risks of ipsilateral phrenic nerve block and hemidiaphragmatic paralysis (HDP) limit its use in patients with preexisting pulmonary compromise. In a previous Daring Discourse (2017), our resea...

journal_title：Regional anesthesia and pain medicine

authors： Tran DQ,Layera S,Bravo D,Cristi-Sanchéz I,Bermudéz L,Aliste J

更新日期：2019-09-20 00:00:00

abstract：:The COVID-19 outbreak is on the world. While many countries have imposed general lockdown, emergency services are continuing. Healthcare professionals have been infected with the virulent severe acute respiratory syndrome coronavirus-2 (SARS), which spreads by close contact and aerosols. The anesthesiologist is partic...

journal_title：Regional anesthesia and pain medicine

authors： Ashokka B,Chakraborty A,Subramanian BJ,Karmakar MK,Chan V

更新日期：2020-07-01 00:00:00