Abstract:
:For the design of new synthetic substrates for the assay of pancreatic lipases activity, acyl dialkylglycerols of variable chain length were prepared. Titrimetric assay of these substrates showed the highest lipolytic activity of porcine pancreas lipase (pPL) with butanoyl dibutylglycerol. The activity is lower but comparable to that shown by pPL towards the classical substrate tributyrin. The 4-nitrophenylcarbonate of 1,2-di-O-butylglycerol, has been prepared and proposed as synthetic substrate for a new spectrophotometric assay of pancreatic lipases.
journal_name
Chem Phys Lipidsjournal_title
Chemistry and physics of lipidsauthors
Ciuffreda P,Loseto A,Manzocchi A,Santaniello Edoi
10.1016/s0009-3084(01)00143-8subject
Has Abstractpub_date
2001-06-01 00:00:00pages
105-10issue
2eissn
0009-3084issn
1873-2941pii
S0009308401001438journal_volume
111pub_type
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journal_title:Chemistry and physics of lipids
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