Abstract:
BACKGROUND AND PURPOSE:Comprehensive metabolic evaluation has become an important aspect of the management of recurrent nephrolithiasis, yet the role of stone analysis is often neglected or perhaps underestimated. The purpose of this study was to determine the role of stone analysis in medical decision making in patients with recurrent nephrolithiasis. MATERIALS AND METHODS:We evaluated 100 consecutive stone-forming patients who had undergone compositional stone analysis as well as comprehensive metabolic evaluation at our institution. An analysis of stone composition in relation to metabolic disturbances was performed. Patients were stratified into two groups: calcium and non-calcium stone formers. RESULTS:Patients having non-calcium stones were found to have a metabolic analysis reflecting specific metabolic disorders. Alternatively, patients with calcium stones were heterogeneous with regard to metabolic disorders, but there was a significant likelihood of renal tubular acidosis in those patients with calcium phosphate calculi. On the basis of these results, a simplified metabolic evaluation and nonselective medical therapy based on stone composition was formulated to facilitate assessment, management, and monitoring of stone disease. CONCLUSIONS:Compositional stone analysis should be an integral part of the metabolic evaluation of patients with nephrolithiasis. Moreover, stone analysis alone may provide guidance for therapeutic treatment and obviate a formal metabolic evaluation.
journal_name
J Endouroljournal_title
Journal of endourologyauthors
Kourambas J,Aslan P,Teh CL,Mathias BJ,Preminger GMdoi
10.1089/089277901750134548subject
Has Abstractpub_date
2001-03-01 00:00:00pages
181-6issue
2eissn
0892-7790issn
1557-900Xjournal_volume
15pub_type
杂志文章abstract:BACKGROUND AND PURPOSE:Transurethral resection of the bladder (TURB), the first step in treatment of patients with urothelial bladder cancers, is limited by technicalities, surgeon skill, and random chance. When high-risk superficial diseases are discovered, a repeated TURB is indicated. We reviewed current literature ...
journal_title:Journal of endourology
pub_type: 杂志文章,meta分析,评审
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更新日期:2011-11-01 00:00:00
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journal_title:Journal of endourology
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journal_title:Journal of endourology
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更新日期:2004-11-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1993.7.289
更新日期:1993-08-01 00:00:00
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journal_title:Journal of endourology
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journal_title:Journal of endourology
pub_type: 临床试验,杂志文章
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更新日期:2011-04-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1994.8.29
更新日期:1994-02-01 00:00:00
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journal_title:Journal of endourology
pub_type: 临床试验,杂志文章
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journal_title:Journal of endourology
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journal_title:Journal of endourology
pub_type: 杂志文章
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journal_title:Journal of endourology
pub_type: 杂志文章
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2002-10-01 00:00:00
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journal_title:Journal of endourology
pub_type: 临床试验,杂志文章
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更新日期:2011-04-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/089277901750426337
更新日期:2001-08-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2021-01-20 00:00:00
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journal_title:Journal of endourology
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更新日期:2015-10-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2007-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:1998-12-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2012-03-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
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更新日期:2003-11-01 00:00:00
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