No effect of 50 Hz magnetic field observed in a pilot study on pentylenetetrazol-induced seizures and mortality in mice.

abstract：:Status epilepticus (SE) is a common neurological and medical emergency. Despite the significant mortality associated with SE, no human data have been available regarding cardiovascular changes prior to death in patients with this condition. This study was conducted to measure hemodynamic trends in the 24 h prior to de...

journal_title：Epilepsy research

authors： Boggs JG,Marmarou A,Agnew JP,Morton LD,Towne AR,Waterhouse EJ,Pellock JM,DeLorenzo RJ

更新日期：1998-08-01 00:00:00

abstract：PURPOSE:To discern more static and lesion based from more dynamic epilepsy-driven features of depression and personality in focal symptomatic epilepsy, change in personality and mood was examined as a function of focus lateralization and seizure outcome after epilepsy surgery. METHODS:Self-reported personality and dep...

journal_title：Epilepsy research

authors： Witt JA,Hollmann K,Helmstaedter C

更新日期：2008-12-01 00:00:00

abstract：:Involvement of opioid systems in the pathogenesis of absence epilepsy has been postulated. However, the role of the mu opioid receptor has not been fully elucidated as yet. In the present study the role of this receptor in absence epilepsy was investigated autoradiographically and pharmacologically. The density of mu ...

journal_title：Epilepsy research

authors： Przewłocka B,Lasoń W,Turchan J,de Bruin N,van Luijtelaar G,Przewłocki R,Coenen A

更新日期：1998-01-01 00:00:00

abstract：:A partially purified extract from American ginseng has been shown to have anticonvulsant activity. To identify the active components in this extract, the activities of the individual ginsenosides (Rb(1), Rb(3) and Rd), mixtures of the purified ginsenosides and a newly prepared Rb fraction were determined. One hour aft...

journal_title：Epilepsy research

authors： Lian XY,Zhang Z,Stringer JL

更新日期：2006-08-01 00:00:00

abstract：:The anticonvulsant activities of a noncompetitive (GYKI 52466) and a competitive (NBQX) AMPA/kainate antagonist were compared in the maximal electroshock (MES) seizure test and various chemoconvulsant models. Both antagonists were protective in the MES and pentylenetetrazol tests. GYKI 52466 was also protective agains...

journal_title：Epilepsy research

authors： Yamaguchi S,Donevan SD,Rogawski MA

更新日期：1993-07-01 00:00:00

abstract：PURPOSE:Pyridoxine-dependent epilepsy (PDE) is a rare autosomal recessive disorder caused by mutations of the ALDH7A1 gene. We aimed to analyze the relations between the clinical diagnosis and treatment of PDE and ALDH7A1 gene mutations in Chinese PDE patients. METHODS:The clinical manifestations, diagnosis and treatm...

journal_title：Epilepsy research

authors： Xue J,Qian P,Li H,Wu Y,Liu X,Yang Z

更新日期：2015-12-01 00:00:00

abstract：:The present study examined whether the perceived behavioral problems of children with idiopathic epilepsy differed from those of healthy controls according to parent proxy-reports and which factors are associated with these problems. The parents of 106 children with idiopathic epilepsy and 305 healthy controls aged 6-...

journal_title：Epilepsy research

authors： Dafoulis V,Kalyva E

更新日期：2012-06-01 00:00:00

abstract：:The motivational consequences of kindling were examined in the conditioned place preference paradigm. In a distinctive environment, rats received stimulation of the amygdala that triggered afterdischarge (AD) alone or AD and generalized seizures. After 4 conditioning trials, preference for the conditioning environment...

journal_title：Epilepsy research

authors： Corcoran ME,Lanius R,Duren A

更新日期：1992-12-01 00:00:00

abstract：:Alterations in the level of consciousness may render the interpretation of the memory test results from the intracarotid amobarbital procedure difficult. The present study was designed to investigate the impact of inattention and somnolence on memory performance during the Amytal test. Nineteen consecutive patients un...

journal_title：Epilepsy research

authors： Malmgren K,Bilting M,Hagberg I,Hedström A,Silfvenius H,Starmark JE

更新日期：1992-09-01 00:00:00

abstract：:Recently, mutations of KCNQ2 or KCNQ3, members of the KCNQ-related K(+)-channel (KCNQ-channel) family, were identified as cause of benign familial neonatal convulsions (BFNC). However, the exact pathogenic mechanisms of age-dependent development and spontaneous remission of BFNC remain to be elucidated. To clarify the...

journal_title：Epilepsy research

authors： Okada M,Zhu G,Hirose S,Ito KI,Murakami T,Wakui M,Kaneko S

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Large administrative databases may prove useful to assess epilepsy-related comorbidity and mortality. Despite their increased use, their validity as data source in epilepsy is yet under-ascertained. METHODS:Achmea is a large Dutch health insurance company covering about 25% of the population. We performed a...

journal_title：Epilepsy research

authors： Wassenaar M,Carpay JA,Sander JW,Thijs RD

更新日期：2018-01-01 00:00:00

abstract：:There is strong evidence that epileptic seizures occur in diurnal or 24-h patterns. A study in rat models of partial epilepsy showed circadian seizure patterns, and in humans circadian rhythmicity in interictal discharges has been found, suggesting that circadian rhythm may play a role in epilepsy. Circadian influence...

journal_title：Epilepsy research

authors： Hofstra WA,Gordijn MC,van der Palen J,van Regteren R,Grootemarsink BE,de Weerd AW

更新日期：2011-05-01 00:00:00

abstract：:In this second paper the clinical features and electrophysiological underpinnings of more complex psychotic states associated with epilepsy are reviewed. (a) Complex partial status epilepticus, in particular of temporal lobe origin, may result in mental states remarkably similar to those seen in the primary psychoses....

journal_title：Epilepsy research

authors： Elliott B,Joyce E,Shorvon S

更新日期：2009-08-01 00:00:00

abstract：:Since magnetic resonance imaging (MRI) technique is constantly evolving with higher field strength scanners, the question arises whether images from different field strength scanners can be used interchangeably for scientific and clinical purposes. We address this issue in a study group of patients with temporal lobe ...

journal_title：Epilepsy research

authors： Scorzin JE,Kaaden S,Quesada CM,Müller CA,Fimmers R,Urbach H,Schramm J

更新日期：2008-11-01 00:00:00

abstract：:The present study aimed at investigating to what extent the regulation of excitability in cortical networks, as indicated by surface-negative slow cortical potentials (SCPs), is impaired in epileptic patients and to what extent training of SCP self-regulation by means of biofeedback and instrumental learning procedure...

journal_title：Epilepsy research

authors： Rockstroh B,Elbert T,Birbaumer N,Wolf P,Düchting-Röth A,Reker M,Daum I,Lutzenberger W,Dichgans J

更新日期：1993-01-01 00:00:00

abstract：:The Third Eilat Conference on New Antiepileptic Drugs was held at the Royal Beach Hotel from May 27 to May 30, 1996. Epileptologists and scientists from 20 countries attended the conference, which was held to discuss critical issues in drug development, new antiepileptic drugs (AEDs) in development, progress reports a...

journal_title：Epilepsy research

authors： Bialer M,Johannessen SI,Kupferberg HJ,Levy RH,Loiseau P,Perucca E

更新日期：1996-11-01 00:00:00

abstract：PURPOSE:Clobazam (CLB, 1,5-benzodiazepine, 1,5-BZP) has been reported to show unique antiepileptic action profile distinguishing from standard 1,4-BZPs. To further elucidate the action profile of CLB, its effects on the abnormal circling fits (ACFs) and generalized tonic-clonic convulsions (GTCs) in Ihara epileptic rat...

journal_title：Epilepsy research

authors： Miura Y,Amano S,Torii R,Ihara N

更新日期：2002-05-01 00:00:00

abstract：PURPOSE:Focal cortical dysplasia (FCD) has been recognized as one of the most frequent causes of drug resistant epilepsy, especially in children. In infancy, onset of FCD-related epilepsy is substantially characterized by epileptic spasms (ES) or focal seizures. Which elements pertaining to the FCD are responsible for ...

journal_title：Epilepsy research

authors： Serino D,Freri E,Ragona F,D'Incerti L,Bernardi B,Di Ciommo V,Granata T,Vigevano F,Fusco L

更新日期：2015-01-01 00:00:00

abstract：:Although accumulating evidence indicates that the immunomodulatory medication thalidomide exerts anticonvulsant properties, the mechanisms underlying such effects of thalidomide are still unknown. Our previous preclinical study suggested that nitric oxide (NO) signaling may be involved in the anticonvulsant effects of...

journal_title：Epilepsy research

authors： Pourshadi N,Rahimi N,Ghasemi M,Faghir-Ghanesefat H,Sharifzadeh M,Dehpour AR

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:To analyze electroclinical features of absence seizures during sleep. PRINCIPAL RESULTS:30 children with genetic generalized epilepsy had 52 paroxysms of GSW >2s during sleep. 18/52 (35%) demonstrated a clinical sign. Ictal GSW lasted an average of 6.5s. CONCLUSION:Motor manifestations are seen during GSW>2s ...

journal_title：Epilepsy research

authors： Sadleir LG,Farrell K,Smith S,Connolly MB,Scheffer IE

更新日期：2011-02-01 00:00:00

abstract：:We examined the influence of seizures and carbamazepine (CBZ) on spiking rates in kindled cats. In the first experiment, spiking rates were measured before and after seizures, with and without CBZ. CBZ was administered immediately after seizures in order not to affect them. Spiking rates were measured over 9 h during ...

journal_title：Epilepsy research

authors： Gigli GL,Gotman J

更新日期：1991-04-01 00:00:00

abstract：:Multiple subpial transection (MST) is an effective surgical therapy for patients with intractable seizures whose epileptogenic lesions lie in the cortex and are unresectable. Morrell developed this procedure and reported clinical results obtained using it. However, only the disappearance of epileptiform discharges aft...

journal_title：Epilepsy research

authors： Sugiyama S,Fujii M,Ito H

更新日期：1995-05-01 00:00:00

abstract：:Weak relationships have been reported between subjective complaints of memory deficits and memory performance in neuropsychological tests in patients with temporal lobe epilepsy (TLE). This study investigated whether the individual exposure to cognitive demands in daily life contributes to cancel out the performance-c...

journal_title：Epilepsy research

authors： Gleissner U,Helmstaedter C,Quiske A,Elger CE

更新日期：1998-11-01 00:00:00

abstract：:The ketogenic diet (KD) increased the expression of calbindin-D(28k) (CB) in the interneurons of the hippocampus compared with the normal diet (ND)-fed mice. Also, 2 days after kainic acid (KA) administration, numerous CB-expressing astrocytes were found in the KD-fed mice compared with those of the ND-fed mice. These...

journal_title：Epilepsy research

authors： Noh HS,Kang SS,Kim DW,Kim YH,Park CH,Han JY,Cho GJ,Choi WS

更新日期：2005-07-01 00:00:00

abstract：:Valproate (VPA) and vigabatrin (gamma-vinyl GABA, GVG) are two novel antiepileptic drugs with a presumed GABAergic mechanism of action. However, for VPA, this aspect has been extensively debated. The aim of the present study was to investigate whether treatment of cultured neurons with clinically relevant concentratio...

journal_title：Epilepsy research

authors： Gram L,Larsson OM,Johnsen AH,Schousboe A

更新日期：1988-03-01 00:00:00

abstract：:This study was carried out to evaluate Synthetic Aperture Magnetometry-kurtosis (SAM(g(2))), a spatially filtered source localization technique in magnetoencephalography (MEG), for identification of epileptogenic areas of focal cortical dysplasia (FCD). Three children with FCD were investigated to localize the ictal o...

journal_title：Epilepsy research

authors： Ishii R,Canuet L,Ochi A,Xiang J,Imai K,Chan D,Iwase M,Takeda M,Snead OC 3rd,Otsubo H

更新日期：2008-10-01 00:00:00

abstract：:Single photon emission computed tomography (SPECT) is increasingly being used as an adjunctive technique in the localisation of epileptogenic foci prior to surgery. As yet, few studies have been undertaken to establish the clinical associations of areas of reduced cerebral perfusion. Sixty-three consecutive patients (...

journal_title：Epilepsy research

authors： Duncan S,Gillen G,Adams FG,Duncan R,Brodie MJ

更新日期：1992-10-01 00:00:00

abstract：:This investigation of cognitive functioning in patients with symptomatic localization-related (partial) epilepsy prior to administration of antiepileptic medication is part of a nationwide prospective, double-blind study of drug efficacy and longitudinal changes in cognition associated with seizure disorders. Recently...

journal_title：Epilepsy research

authors： Prevey ML,Delaney RC,Cramer JA,Mattson RH

更新日期：1998-03-01 00:00:00

abstract：:Novel treatments for epilepsy are necessary because many epilepsy patients are resistant to medication. Metabotropic glutamate receptors (mGluRs), specifically mGluR 2 and 3, may serve as antiepileptic drug targets because of their role in controlling synaptic release. In this study, we administered a Group 2 mGluR ag...

journal_title：Epilepsy research

authors： Caulder EH,Riegle MA,Godwin DW

更新日期：2014-02-01 00:00:00

abstract：:Epilepsy - the world's most common serious brain disorder - is defined by recurrent unprovoked seizures that result from complex interactions between distributed neural populations. We explore some macroscopic characteristics of emergent ictal networks by considering intracranial recordings from human subjects with in...

journal_title：Epilepsy research

authors： Kramer MA,Kolaczyk ED,Kirsch HE

更新日期：2008-05-01 00:00:00