Relation between myofibers and connective tissue during muscle injury repair.

Abstract:

:The connective tissue framework in skeletal muscle combines the contractile myofibers into a functional unit, in which the contraction of myofibers is transformed into movement via myotendinous junctions (MTJs) at their ends, where myofibers attach to tendons/fascia. The cytoskeletal contractile myofilament apparatus adheres through subsarcolemmal and transmembrane molecules to the surrounding extracellular matrix, with integrin and dystrophin associated chains of molecules being the two main adhesion complexes. In shearing type of muscle injury both myofibers and the connective tissue framework are ruptured and thereby the functional tendon-muscle-tendon units are disrupted. The stumps of the ruptured myofibers are separated and at the same time joined by a connective tissue scar, through which the ends of regenerating myofibers try to pierce, but as the scar becomes more compact the ends attach to the scar by new mini-MTJs. During the early phase ruptured myofibers try to compensate for the lost MTJ attachment by reinforcing their integrin mediated lateral adhesion, which returns to normal low level after formation of the mini-MTJs and at which time complementary increase of dystrophin and associated molecules on lateral sarcolemma takes place. The stumps appear to remain separated by and attached to the interposed scar for many months, possibly for ever, i.e. the original tendon-muscle-tendon units may have become permanently divided into two consecutive units. Remarkably, axon sprouts are able to penetrate through the interposed scar to form new neuromuscular junctions on those abjunctional stumps which were denervated by the rupture.

journal_name

Scand J Med Sci Sports

authors

Kääriäinen M,Järvinen T,Järvinen M,Rantanen J,Kalimo H

doi

10.1034/j.1600-0838.2000.010006332.x

subject

Has Abstract

pub_date

2000-12-01 00:00:00

pages

332-7

issue

6

eissn

0905-7188

issn

1600-0838

journal_volume

10

pub_type

杂志文章,评审
  • Effect of overreaching on cognitive performance and related cardiac autonomic control.

    abstract::The purpose of this study was to characterize the effect of a 2-week overload period immediately followed by a 1-week taper period on different cognitive processes including executive and nonexecutive functions, and related heart rate variability. Eleven male endurance athletes increased their usual training volume by...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1111/j.1600-0838.2012.01465.x

    authors: Dupuy O,Lussier M,Fraser S,Bherer L,Audiffren M,Bosquet L

    更新日期:2014-02-01 00:00:00

  • Alpine Skiing With total knee ArthroPlasty (ASWAP): impact on molecular and architectural features of musculo-skeletal ageing.

    abstract::This study investigated features of skeletal muscle ageing in elderly individuals having previously undergone unilateral total knee arthroplasty (TKA) and whether markers of sarcopenia could be mitigated by a 12-week alpine skiing intervention. Novel biomarkers agrin, indicative of neuromuscular junction (NMJ) degener...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1111/sms.12458

    authors: Narici M,Conte M,Salvioli S,Franceschi C,Selby A,Dela F,Rieder F,Kösters A,Müller E

    更新日期:2015-08-01 00:00:00

  • Cross-education of muscle strength: cross-training effects are not confined to untrained contralateral homologous muscle.

    abstract::The aim of this study was to evaluate whether electrical muscle stimulation (EMS) on dominant wrist flexors causes an increase in the muscle strength of the contralateral wrist extensors. Twenty-three healthy, young, adult men were included in this prospective, double-blind, controlled study. Participants were randoml...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-0838.2011.01311.x

    authors: Sariyildiz M,Karacan I,Rezvani A,Ergin O,Cidem M

    更新日期:2011-12-01 00:00:00

  • Effects of training on functional performance in 65, 75 and 85 year-old women: experiences deriving from community based studies in Odense, Denmark.

    abstract::The aim of the Odense training studies is to elucidate if regular physical training influences the expected decline in physical functional ability in order to assess capacity for postponing dependence in old age. All participants were healthy community-dwelling women representing three different age-cohorts of 65, 75 ...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1034/j.1600-0838.2003.00302.x

    authors: Puggaard L

    更新日期:2003-02-01 00:00:00

  • Electromyographic adjustments during continuous and intermittent incremental fatiguing cycling.

    abstract::We studied the sensitivity of electromyographic (EMG) variables to load and muscle fatigue during continuous and intermittent incremental cycling. Fifteen men attended three laboratory sessions. Visit 1: lactate threshold, peak power output, and VO2max . Visits 2 and 3: Continuous (more fatiguing) and intermittent (le...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1111/sms.12578

    authors: Martinez-Valdes E,Guzman-Venegas RA,Silvestre RA,Macdonald JH,Falla D,Araneda OF,Haichelis D

    更新日期:2016-11-01 00:00:00

  • Hamstring injury prevention in soccer: Before or after training?

    abstract::We examined the effects of a 12-week program of Nordic hamstring exercises (NHE), administered before or after football training, upon eccentric hamstring strength, muscle activity, and architectural adaptations. Amateur soccer players were randomized into three groups. The control group (CON; n=11) undertook core sta...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/sms.12925

    authors: Lovell R,Knox M,Weston M,Siegler JC,Brennan S,Marshall PWM

    更新日期:2018-02-01 00:00:00

  • Effect of whey protein- and carbohydrate-enriched diet on glycogen resynthesis during the first 48 h after a soccer game.

    abstract::The effect of a whey protein- and carbohydrate (CHO)-enriched diet on the rate of muscle glycogen resynthesis after a soccer match was examined. Sixteen elite soccer players were randomly assigned to a group ingesting a diet rich in carbohydrates and whey protein [CHO, protein, and fat content was 71, 21, and 8E%, res...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-0838.2011.01418.x

    authors: Gunnarsson TP,Bendiksen M,Bischoff R,Christensen PM,Lesivig B,Madsen K,Stephens F,Greenhaff P,Krustrup P,Bangsbo J

    更新日期:2013-08-01 00:00:00

  • Patients with schizophrenia have impaired muscle force-generating capacity and functional performance.

    abstract::Patients with schizophrenia have impaired physical health. However, evidence of how skeletal muscle force-generating capacity (FGC), a key component of functional performance, may contribute to the impairment is scarce. Thus, the aim of this study was to investigate the patient groups' skeletal muscle FGC and its asso...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1111/sms.13526

    authors: Nygård M,Brobakken MF,Roel RB,Taylor JL,Reitan SK,Güzey IC,Morken G,Vedul-Kjelsås E,Wang E,Heggelund J

    更新日期:2019-12-01 00:00:00

  • Influence of nitrate supplementation on VO₂ kinetics and endurance of elite cyclists.

    abstract::The present study examined if an elevated nitrate intake would improve VO(2) kinetics, endurance, and repeated sprint capacity in elite endurance athletes. Ten highly trained cyclists (72 ± 4 mL O(2) /kg/min, mean ± standard deviation) underwent testing for VO(2) kinetics (3 × 6 min at 298 ± 28 W), endurance (120 min ...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/sms.12005

    authors: Christensen PM,Nyberg M,Bangsbo J

    更新日期:2013-02-01 00:00:00

  • Characteristics of acute groin injuries in the adductor muscles: A detailed MRI study in athletes.

    abstract::Acute adductor injuries account for the majority of acute groin injuries; however, little is known about specific injury characteristics, which could be important for the understanding of etiology and management of these injuries. The study aim was to describe acute adductor injuries in athletes using magnetic resonan...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1111/sms.12936

    authors: Serner A,Weir A,Tol JL,Thorborg K,Roemer F,Guermazi A,Yamashiro E,Hölmich P

    更新日期:2018-02-01 00:00:00

  • Exercise-mediated modulation of autophagy in skeletal muscle.

    abstract::Although exercise exerts multiple beneficial health effects, it may also damage cellular structures. Damaged elements are continuously degraded and its constituents recycled to produce renovated structures through a process called autophagy, which is essential for the adaptation to training. Autophagy is particularly ...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章,评审

    doi:10.1111/sms.12945

    authors: Martin-Rincon M,Morales-Alamo D,Calbet JAL

    更新日期:2018-03-01 00:00:00

  • Performing a forward dive with 5.5 somersaults in platform diving: simulation of different technique variations.

    abstract::Performing dives with multiple somersaults is an inherent component of competitive diving. In individual international competitions, dives are performed from a 1- or 3-m springboard as well as from a 10-m platform, and divers use different technique variations in accelerating and decelerating rotation about the somers...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1111/sms.12728

    authors: Heinen T,Supej M,Čuk I

    更新日期:2017-10-01 00:00:00

  • The role of prediagnostic data in injury epidemiology in preprofessional dancers.

    abstract:INTRODUCTION:preprofessional dance training starts at very early ages, on a highly demanding environment placing students at significant risk for injury. Injury management and prevention are a matter of concern. Given the constant interchangeability of risk factors, identifying injury patterns may prove to be equally a...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1111/sms.13382

    authors: Moita JP,Gomes A,Xarez L,Coelho C

    更新日期:2019-04-01 00:00:00

  • Does type 1 diabetes alter post-exercise thermoregulatory and cardiovascular function in young adults?

    abstract::Recent data demonstrated that individuals with type 1 diabetes mellitus (T1DM) exhibit impaired sweating and increased rectal temperature (i.e., heat storage) during exercise compared with healthy controls. Our purpose in this study was to investigate the consequences of T1DM on post-exercise thermal homeostasis. Sixt...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1111/sms.12344

    authors: McGinn R,Carter MR,Barrera-Ramirez J,Sigal RJ,Flouris AD,Kenny GP

    更新日期:2015-10-01 00:00:00

  • Ability of closed and open kinetic chain tests of muscular strength to assess functional performance.

    abstract::The purpose of this study was to investigate the ability of closed and open kinetic chain tests of muscular strength to assess functional performance. Sixteen healthy male subjects, with a mean (+/-SD) age, body mass and height of 27+/-5 years, 78+/-9 kg and 183+/-9 cm, respectively, volunteered to participate in the ...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1034/j.1600-0838.2000.010003164.x

    authors: Augustsson J,Thomeé R

    更新日期:2000-06-01 00:00:00

  • Description of pain provocation tests used for the diagnosis of sports-related chronic groin pain: relationship of tests to defined clinical (pain and tenderness) and MRI (pubic bone marrow oedema) criteria.

    abstract::The clinical assessment of groin pain in athletes is difficult, with the lack of specific clinical tests being in part responsible. Three pain provocation tests used in the diagnosis of chronic groin pain are described and their relationship to defined clinical and MRI criteria has been assessed. Eighty-nine Australia...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1111/j.1600-0838.2004.00380.x

    authors: Verrall GM,Slavotinek JP,Barnes PG,Fon GT

    更新日期:2005-02-01 00:00:00

  • Correlates of regular exercise during pregnancy: the Norwegian Mother and Child Cohort Study.

    abstract::The aims of this study were to describe the level of exercise during pregnancy and to assess factors associated with regular exercise. Using data from the Norwegian Mother and Child Cohort Study conducted by the Norwegian Institute of Public Health, 34 508 pregnancies were included in the present study. Data were coll...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1111/j.1600-0838.2008.00840.x

    authors: Owe KM,Nystad W,Bø K

    更新日期:2009-10-01 00:00:00

  • Facts, noise and wishful thinking: muscle protein turnover in aging and human disuse atrophy.

    abstract::Surprisingly little is known about the mechanisms of muscle atrophy with aging and disuse in human beings, in contrast to rodents, from which much has been extrapolated to explain the human condition. However, this extrapolation is likely unwarranted because the time course, extent of wasting, muscle fiber involvement...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0838.2009.00967.x

    authors: Rennie MJ,Selby A,Atherton P,Smith K,Kumar V,Glover EL,Philips SM

    更新日期:2010-02-01 00:00:00

  • Hydration and sweating responses to hot-weather football competition.

    abstract::During a football match played in warm (34.3 ± 0.6 °C), humid (64 ± 2% rh) conditions, 22 male players had their pre-match hydration status, body mass change, sweat loss and drinking behavior assessed. Pre-match urine specific gravity (1.012 ± 0.006) suggested that all but three players commenced the match euhydrated....

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1111/j.1600-0838.2010.01218.x

    authors: Kurdak SS,Shirreffs SM,Maughan RJ,Ozgünen KT,Zeren C,Korkmaz S,Yazici Z,Ersöz G,Binnet MS,Dvorak J

    更新日期:2010-10-01 00:00:00

  • Altered relationship between R-R interval and R-R interval variability in endurance athletes with overtraining syndrome.

    abstract::Autonomic dysfunction decreases within-subject correlation between R-R interval length (RRi) and vagally mediated RRi variability in cardiac disease. We tested the hypothesis that overtraining syndrome (OTS) may also weaken this relationship. Nine OTS and 10 control endurance athletes underwent 24-h electrocardiogram ...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1111/sms.12114

    authors: Kiviniemi AM,Tulppo MP,Hautala AJ,Vanninen E,Uusitalo AL

    更新日期:2014-04-01 00:00:00

  • Factors influencing isometric exercise training-induced reductions in resting blood pressure.

    abstract::Hypertension is a major health concern, and current recommendations for blood pressure management (lifestyle modifications and pharmacological intervention) have not been universally successful. For two decades, isometric exercise training (IET) has become established as effective at reducing in resting BP (RBP) in a ...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章,评审

    doi:10.1111/sms.12225

    authors: Lawrence MM,Cooley ID,Huet YM,Arthur ST,Howden R

    更新日期:2015-04-01 00:00:00

  • Effects of contract-relax vs static stretching on stretch-induced strength loss and length-tension relationship.

    abstract::The purpose of this study was to determine the acute effects of contract-relax stretching (CRS) vs static stretching (SS) on strength loss and the length-tension relationship. We hypothesized that there would be a greater muscle length-specific effect of CRS vs SS. Isometric hamstring strength was measured in 20 healt...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/sms.12399

    authors: Balle SS,Magnusson SP,McHugh MP

    更新日期:2015-12-01 00:00:00

  • Cardiorespiratory fitness in aging men and women: the DR's EXTRA study.

    abstract::The aim of the study was to describe the levels and to create reference values of cardiorespiratory fitness, expressed as maximal oxygen consumption (VO(2max) ), maximal metabolic equivalents (METs) and maximal workload in aging men and women. We measured VO(2max) directly by a breath-by-breath method during a maximal...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-0838.2010.01127.x

    authors: Hakola L,Komulainen P,Hassinen M,Savonen K,Litmanen H,Lakka TA,Rauramaa R

    更新日期:2011-10-01 00:00:00

  • In-season changes in heart rate recovery are inversely related to time to exhaustion but not aerobic capacity in rowers.

    abstract::To determine if in-season changes in heart rate recovery (HRR) are related to aerobic fitness and performance in collegiate rowers. Twenty-two female collegiate rowers completed testing before and after their competitive season. Body fat percentage (BF%) was determined by dual-energy X-ray absorptiometry. Maximal aero...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1111/sms.12934

    authors: Haraldsdottir K,Brickson S,Sanfilippo J,Dunn W,Watson A

    更新日期:2018-02-01 00:00:00

  • Post-resistance exercise hemodynamic and autonomic responses: Comparison between normotensive and hypertensive men.

    abstract::To compare post-resistance exercise hypotension (PREH) and its mechanisms in normotensive and hypertensive individuals, 14 normotensives and 12 hypertensives underwent two experimental sessions: control (rest) and exercise (seven exercises, three sets, 50% of one repetition maximum). Hemodynamic and autonomic clinic m...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1111/sms.12280

    authors: Queiroz AC,Sousa JC,Cavalli AA,Silva ND Jr,Costa LA,Tobaldini E,Montano N,Silva GV,Ortega K,Mion D Jr,Tinucci T,Forjaz CL

    更新日期:2015-08-01 00:00:00

  • Do anthropometric and fitness characteristics vary according to birth date distribution in elite youth academy soccer players?

    abstract::We examined whether maturity, anthropometric profiles and fitness measures vary according to birth date distribution in elite, under-14 youth academy soccer players. The selection year was divided into four quarters, with 160 male players grouped according to individual birth date. Players had their skeletal age deter...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1111/j.1600-0838.2008.00867.x

    authors: Carling C,le Gall F,Reilly T,Williams AM

    更新日期:2009-02-01 00:00:00

  • Correlates of physical activity parenting: The Skilled Kids study.

    abstract::We examined the relationship between physical activity parenting (PAP) and child, family, and environmental factors in families. The participants were 840 families with young children (n = 993; 5.40 ± 1.14 years) and parents (n = 993; 35.8 ± 5.29 years). Parents' self-reported PAP (co-participation, (in)direct support...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1111/sms.13287

    authors: Laukkanen A,Niemistö D,Finni T,Cantell M,Korhonen E,Sääkslahti A

    更新日期:2018-12-01 00:00:00

  • Isolated hip and ankle fatigue are unlikely risk factors for anterior cruciate ligament injury.

    abstract::Lower extremity neuromuscular fatigue purportedly increases anterior cruciate ligament (ACL) injury risk through promotion of extreme landing mechanics. However, the impact of fatigue on muscle groups critical to the landing strategy remains unclear. This study examined the effects of isolated hip rotator and triceps ...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1111/j.1600-0838.2009.01076.x

    authors: Thomas AC,Palmieri-Smith RM,McLean SG

    更新日期:2011-06-01 00:00:00

  • The epidemiology of kicking injuries in professional Rugby Union: A 15-season prospective study.

    abstract:PURPOSE:While kicking in Rugby Union can be influential to match outcome, the epidemiology of kicking injuries remains unknown. This study therefore aimed to investigate the epidemiology of injuries attributed to kicking in professional rugby, including playing position-specific effects and differences in kicking volum...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1111/sms.13737

    authors: Lazarczuk SL,Love T,Cross MJ,Stokes KA,Williams S,Taylor AE,Fuller CW,Brooks JHM,Kemp SPT,Bezodis NE

    更新日期:2020-09-01 00:00:00

  • Muscle contractile properties of cancer patients receiving chemotherapy: Assessment of feasibility and exercise effects.

    abstract:BACKGROUND:This pilot trial explores the feasibility of measuring muscle contractile properties in patients with cancer, effects of exercise during chemotherapy on muscle contractile properties and the association between changes in contractile muscle properties and perceived fatigue. METHOD:Patients who received (neo...

    journal_title:Scandinavian journal of medicine & science in sports

    pub_type: 杂志文章

    doi:10.1111/sms.13758

    authors: Buffart LM,Sweegers MG,de Ruijter CJ,Konings IR,Verheul HMW,van Zweeden AA,Grootscholten C,Chinapaw MJ,Altenburg TM

    更新日期:2020-10-01 00:00:00