Abstract：
:Surprisingly little is known about the mechanisms of muscle atrophy with aging and disuse in human beings, in contrast to rodents, from which much has been extrapolated to explain the human condition. However, this extrapolation is likely unwarranted because the time course, extent of wasting, muscle fiber involvement and alterations of muscle protein turnover are all quite different in rodent and human muscle. Furthermore, there is little evidence that static indices of protein turnover represent dynamic changes and may be misleading. With disuse there are reductions in the rate of muscle protein synthesis (MPS) large enough to explain the atrophic loss of muscle protein without a concomitant increase in proteolysis. In aging, there is no evidence that there are marked alterations in basal muscle protein turnover in healthy individuals but instead the ability to maintain muscle after feeding is compromised. This anabolic resistance is evident with physical inactivity, which exacerbates the inability to maintain muscle mass with aging. The main conclusion of this review is that in uncomplicated, non-inflammatory disuse atrophy, the facilitative change causing loss of muscle mass is a depression of MPS, exacerbated by anabolic resistance during feeding, with possible adaptive depressions, rather than increases, of muscle proteolysis.
journal_name
Scand J Med Sci Sportsjournal_title
Scandinavian journal of medicine & science in sportsauthors
Rennie MJ,Selby A,Atherton P,Smith K,Kumar V,Glover EL,Philips SMdoi
10.1111/j.1600-0838.2009.00967.xsubject
Has Abstractpub_date
2010-02-01 00:00:00pages
5-9issue
1eissn
0905-7188issn
1600-0838pii
SMS967journal_volume
20pub_type
杂志文章,评审abstract：:We examined the effect of curcumin (CUR) ingestion before or after exercise on changes in muscle damage and inflammatory responses after exercise. We conducted two parallel experiments with different CUR ingestion timings using a double-blind crossover. In Exp. 1, ten healthy men ingested 180 mg d-1 of CUR or placebo ...
journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章,随机对照试验
doi：10.1111/sms.13373
更新日期：2019-04-01 00:00:00
abstract：PURPOSE:While kicking in Rugby Union can be influential to match outcome, the epidemiology of kicking injuries remains unknown. This study therefore aimed to investigate the epidemiology of injuries attributed to kicking in professional rugby, including playing position-specific effects and differences in kicking volum...
journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章
doi：10.1111/sms.13737
更新日期：2020-09-01 00:00:00
abstract：:Hypertension is a major health concern, and current recommendations for blood pressure management (lifestyle modifications and pharmacological intervention) have not been universally successful. For two decades, isometric exercise training (IET) has become established as effective at reducing in resting BP (RBP) in a ...
journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章,评审
doi：10.1111/sms.12225
更新日期：2015-04-01 00:00:00
abstract：:To compare the effects of three 7-week interval training programs varying in work period duration but matched for effort in trained recreational cyclists. Thirty-five cyclists (29 male, 6 female, VO(2peak) 52 ± 6 mL kg/min) were randomized to four training groups with equivalent training the previous 2 months (∼6 h/wk...
journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1600-0838.2011.01351.x
更新日期：2013-02-01 00:00:00
abstract：:This study aimed (a) to estimate the transition rate for top 50 ranked track and field jumpers, (b) to compare the performance progression of top 50 ranked senior jumpers (top50 senior) to those who failed to be top 50 ranked in the senior category despite being top 50 ranked in the under 18 category (only U18), and (...
journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章
doi：10.1111/sms.13819
更新日期：2021-01-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章,随机对照试验
doi：10.1111/sms.12925
更新日期：2018-02-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章
doi：10.1111/j.1600-0838.2007.00720.x
更新日期：2008-08-01 00:00:00
abstract：:Acute acetaminophen (ACT) ingestion has been reported to reduce thermal strain during cycling in the heat. In this study, nine active participants ingested 20 mg of ACT per kg of total body mass (ACT) or a placebo (PLA), 60 min prior to cycling at a fixed rate of metabolic heat production (ACT: 8.3 ± 0.3 W/kg; PLA: 8....
journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章,随机对照试验
doi：10.1111/sms.12336
更新日期：2015-06-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章
doi：10.1111/sms.12889
更新日期：2018-01-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章
doi：10.1111/j.1600-0838.2012.01491.x
更新日期：2014-02-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章
doi：10.1111/j.1600-0838.2004.377.x
更新日期：2004-12-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章
doi：10.1111/j.1600-0838.2010.01144.x
更新日期：2012-02-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章,meta分析
doi：10.1111/j.1600-0838.2010.01246.x
更新日期：2011-02-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章
doi：10.1111/sms.12272
更新日期：2015-08-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章
doi：10.1111/j.1600-0838.2007.00756.x
更新日期：2009-02-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章
doi：10.1111/sms.12918
更新日期：2018-02-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章
doi：10.1111/sms.12614
更新日期：2016-11-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章
doi：10.1111/j.1600-0838.2009.00933.x
更新日期：2010-02-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章,随机对照试验
doi：10.1111/sms.13014
更新日期：2018-03-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章
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更新日期：1997-04-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章,随机对照试验
doi：10.1111/sms.12827
更新日期：2017-12-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章
doi：10.1111/j.1600-0838.2009.01065.x
更新日期：2011-08-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章,随机对照试验
doi：10.1111/sms.12007
更新日期：2013-02-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1997-06-01 00:00:00
abstract：:The purpose of this study was to examine the effect of strapping on different components of motor performance of wrist and ankle joints. The subjects were 14 healthy volunteers (12 females, two males), aged 21-33 years, with no known previous injuries of the ankle and wrist joints. The measurements were made with the ...
journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章
doi：10.1111/j.1600-0838.1997.tb00146.x
更新日期：1997-08-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章,评审
doi：10.1034/j.1600-0838.2003.02477.x
更新日期：2003-04-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章
doi：10.1034/j.1600-0838.2002.00142.x
更新日期：2002-08-01 00:00:00
abstract：:The purpose of this study was to develop a grounded theory of the process of inspirational coach leadership in sport. A Straussian grounded theory methodology was used. Semi-structured interviews and focus groups were conducted with athletes (n = 22) and coaches (n = 15). Data were analyzed through a process of open a...
journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章
doi：10.1111/sms.13513
更新日期：2019-11-01 00:00:00
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journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章
doi：10.1111/sms.13287
更新日期：2018-12-01 00:00:00
abstract：:The purpose of this study was to investigate the influence of perceived motivational climate and gender on sportspersonship behavior of competitive youth football players. Participants were 512 boy and 202 girl Norwegian youth football players (12-14 years old) competing in an international football tournament. A 2 x ...
journal_title：Scandinavian journal of medicine & science in sports
pub_type： 杂志文章
doi：10.1111/j.1600-0838.2003.00320.x
更新日期：2004-06-01 00:00:00
