[Determination of NMP-22 as recurrence marker in bladder cancer. Preliminary study].

Abstract:

OBJECTIVES:The present study was conducted to determine the efficacy of NMP-22 as a diagnostic test for recurrence of bladder tumors and to compare its efficacy with urine cytology. METHODS:30 patients (25 male, 5 female), aged 41-87 years (mean 73.4), with bladder tumor were evaluated by cytology, cystoscopy and determination of NMP-22 at 3 and 6 months post-TUR of the bladder. A positive test was defined as NMP-22 greater than 10 U/ml. RESULTS:80.7% were T1, 15.3% T2-T3, 76.8% were grade I and II, and 23.2% were grade III. NMP-22 showed a sensitivity of 69%, a specificity of 64%, a positive predictive value of 52% and a negative predictive value of 78%, using tumor recurrence at 3 and 6 months as the unit of analysis, for a recurrence rate of 36%. Cytology showed a sensitivity of 44%, a specificity of 92%, a positive predictive value of 77% and a negative predictive value of 74%. When both tests were used, we obtained a sensitivity of 87.5%, a specificity of 64.2%, a positive predictive value of 58.3% and a negative predictive value of 90%. In grade I tumors, determination of NMP-22 had a sensitivity of 100%, a specificity of 77.7%, a positive predictive value of 60% and a negative predictive value of 69%. CONCLUSIONS:NMP-22 showed an acceptable sensitivity but a low positive predictive value, therefore control cystoscopic evaluation cannot be avoided. The sensitivity and negative predictive values increased when NMP-22 and cytology are used in combination. We found NMP-22 to be a very useful marker for recurrence of low grade tumors.

journal_name

Arch Esp Urol

authors

Pérez García FJ,Escaf Barmadah S,Fernández Gómez JM,Rodríguez Martínez JJ,Martín Benito JL

subject

Has Abstract

pub_date

2000-05-01 00:00:00

pages

305-12

issue

4

eissn

0004-0614

issn

1576-8260

journal_volume

53

pub_type

杂志文章
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  • [Bilateral isolated infiltration in the epididymis and sperm cord as first sign of chronic lymphatic leukemia].

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    doi:

    authors: Pérez García FJ,Fernández Gómez JM,Martín Huéscar A,Sahagún Argüello JL,Rábade Rey CJ,Rodríguez Martínez JJ,Pérez del Río MJ

    更新日期:1997-03-01 00:00:00

  • [Validity studies in laparoscopic simulation. Methodology and design considerations.]

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    doi:

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  • [Vesicovaginal fistula in an 8-year-old girl].

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    pub_type: 杂志文章,评审

    doi:

    authors: Unda Urzaiz M,Prieto Ugidos N,Iriarte Soldevilla I,de Soto Arranz C,Flores Corral N

    更新日期:1989-06-01 00:00:00

  • [Cold ischemia and renal graft survival: A paired analysis comparing first and second grafts from the same donor].

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    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章

    doi:

    authors: Puche-Sanz I,Flores-Martín JF,Vázquez-Alonso F,Expósito-Ruiz M,Bravo-Soto J,Vicente-Prados J,Cózar-Olmo JM

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  • Laparoscopic cystectomy: indications and limitations.

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    pub_type: 杂志文章,评审

    doi:

    authors: Carvalhal EF,Gill IS

    更新日期:2002-07-01 00:00:00

  • [The Spanish participation in the Congresses of the International Society of Urology during the 20th century].

    abstract:OBJECTIVES:With the occasion of the Centenary of the Constitution in 1907 of the International Society of Urology, initially named Association, we point at the topics treated and analyze the presence of the Spanish urologists in the foundation act as well as their role and contributions in the meetings during the 20th ...

    journal_title:Archivos espanoles de urologia

    pub_type: 历史文章,杂志文章

    doi:

    authors: Pérez Albacete M,Tornero Ruíz J,Server Pastor G,de León Castell IP

    更新日期:2007-10-01 00:00:00

  • [Induction of micturition in the cat by electric stimulation of the sacral roots].

    abstract::The authors carried out detailed experiments on cats under anaesthesia, with electrical stimulation of the L7, S1, S2 and S3 ventral roots and of the vesical detrusor in order to study their contraction. They varied the frequency, intensity and duration parameters of the stimulation beats, using as contraction index, ...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章

    doi:

    authors: Tallada M,Perales L,Romero J,Buño W Jr

    更新日期:1980-07-01 00:00:00

  • [Primary embryonic rhabdomyosarcoma of the prostate. An unusual location].

    abstract::We report on an 18-year-old patient with embryonal rhabdomyosarcoma of the prostate who presented with urinary retention. An ultrasound-guided percutaneous punction corroborated the presumptive diagnosis. The patient was submitted to the appropriate combined treatment modality of chemotherapy, radiotherapy and surgery...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章

    doi:

    authors: Romero Tenorio M,Fariñas Varo JM,Báez Perea JM,Almaised J,Ramírez Chamorro R,Parra Martínez JL

    更新日期:1989-07-01 00:00:00

  • [Microscopic innervation of the spermatic ducts and testis. I. Vas deferens].

    abstract::The microscopic innervation of the vas deferens in the rat was studied both in light and electron microscope. The nerve fibres form perivascular, intramuscular and subepithelial plexuses. Inside the connective tissue surrounding the vas deferens both isolated nerve fibres and sensory corpuscles (glomerular and Ruffine...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章

    doi:

    authors: Suárez-Garnacho S,Vega JA,Alvarez Arenal A,Pérez Casas A,Alvarez Menéndez JC,Hernández LC

    更新日期:1989-07-01 00:00:00

  • [Testicular malacoplakia].

    abstract::A rare case of testicular malacoplakia is described herein. To our knowledge only 32 cases have been reported up to 1989. The microscopic features are described and the literature is briefly reviewed. ...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章,评审

    doi:

    authors: Lioy Lupis MT,Quintana RM,Monsalve J,Iotti RM

    更新日期:1993-11-01 00:00:00

  • [Medical treatment of uric acid lithiasis of the urinary tract and usefulness of double J catheter].

    abstract:OBJECTIVE:To analyze the utility of chemolysis and the double-J ureteral catheter in patients with uric acid calculi. METHODS:The study comprised 30 patients (28 men and 2 women) treated with chemolysis for uric acid calculi and who consulted for renal colic. The indication for placement of a double-J ureteral stent w...

    journal_title:Archivos espanoles de urologia

    pub_type: 临床试验,杂志文章

    doi:

    authors: Granados Loarca EA

    更新日期:2001-03-01 00:00:00

  • [Fistula between ileal conduit and small intestine after cutaneous ureteroileostomy].

    abstract::We report on a case of ileal conduit-enteric fistula which appeared early after ureteroileostomy using the Bricker technique. The appearance of gastrointestinal content through the stoma was the only sign. An ileogram permitted making the diagnosis. Conservative treatment was instituted and the fistula resolved sponta...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章

    doi:

    authors: Albisu Tristán A,Acha Pérez M,Zabala Egurrola JA,Llarena Ibarguren R,Pertusa Peña C

    更新日期:1992-04-01 00:00:00

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    pub_type: 杂志文章

    doi:

    authors: Emiliani E,Gavrilov P,Mayordomo O,Salvador J,Palou J,Rosales A,Villavicencio H

    更新日期:2017-05-01 00:00:00

  • Endoscopic treatment of recto-vesical fistula after radical prostatectomy. Our findings in 2 patients.

    abstract:OBJECTIVE:The recto-vesical fistula (FRV) that follows a radical prostatectomy is an unusual complication and involves a difficult management. A wide variety of surgical aggressive repair techniques are described in literature, including end-colostomy. Furthermore, non-invasive procedures are barely documented. We pres...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章

    doi:

    authors: Oteo Manjavacas P,Estigarribia Benítez CA,Borrego Hernando J,Martínez Albares JL

    更新日期:2020-11-01 00:00:00

  • [Scholia about the pandemia urbi et orbi et orbe generate by de COVID-19 disease.]

    abstract::The Goddess of Health had two daughters, Panacea and Higinia, the fruit of the first is diagnosis, prognosis and treatment, and the fruit of the second is health management, prevention, and statistics. Humanbeings are unexpectedly subjected to:1. Happenings: they belong to the plane of the personality, crisis, the Age...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章

    doi:

    authors: Coullaut-Valera Jáuregui J,Coullaut-Valera García R,Coullaut-Valera García J,Gómez-Pastrana C

    更新日期:2020-06-01 00:00:00

  • [Urinary lithiasis as a systemic disease.]

    abstract::Urinary lithiasis is a prevalent disorder of uncertain origin which provokes health problems through potential harm to the urinary system, renal parenchyma or the body as a whole, with a frequent trend to relapse. Historically urinary calculi have been studied and treated as an isolated disease but nowadays we know mo...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章

    doi:

    authors: Leanez Jiménez M,Candau Vargas-Zúñiga F,Reina Ruiz C

    更新日期:2017-01-01 00:00:00

  • [Epidermoid carcinoma of the urinary tract. Immunohistochemical study].

    abstract::Six patients diagnosed as having urothelial carcinoma with varying degrees of squamous features are described. Four had pure squamous carcinoma. Two had transitional cell carcinoma (1 with squamous areas and the other had carcinoma in situ). The histological analyses of specimens were performed using immunohistochemic...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章

    doi:

    authors: Salas Valien JS,García Díez F,González Morán MA,Rodríguez López JA,Guerreiro González R

    更新日期:1990-11-01 00:00:00

  • [Paratesticular leiomyosarcoma. Review and update].

    abstract:OBJECTIVES:To present one case of paratesticular leiomyosarcoma, a rare tumor which has been reported in 5 cases only in our country. To review the management of this type of tumor. METHODS:A 73-year-old male presenting with a 4 cm mass adjacent to the right testicle underwent excision of the mass, spermatic cord and ...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章,评审

    doi:

    authors: Llarena Ibarguren R,Azurmendi Sastre V,Martín Bazaco J,Villafruela Mateos A,Eizaguirre Zarza B,Pertusa Peña C

    更新日期:2004-06-01 00:00:00

  • [Characterization of the DURR (dynamic urethral resistance relation] in the study of function lower urinary tract symptoms in the male].

    abstract:OBJECTIVES:To determine the type and to quantify the DURR phenomena in the male. METHODS:We conducted a clinical and urodynamic study in 31 male patients with functional lower urinary tract symptoms. RESULTS:DURR is produced by two types of mechanisms: urethral rigidity and contraction of the urethral wall. The patie...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章

    doi:

    authors: Vírseda Chamorro M,Salinas Casado J,Aristizábal Agudelo JM,Adot Zurbano JM,Esteban Fuertes M,Fernández Ajubita H,Resel Estévez L

    更新日期:1998-01-01 00:00:00

  • [Clinical and ultrasonographic characteristics of prostatic cancer diagnosed with transrectal biopsy].

    abstract:OBJECTIVE:To analyze the clinical, ultrasound and pathological characteristics of patients with prostate cancer diagnosed by ultrasound-guided transrectal biopsy who consulted for lower urinary tract symptoms compatible with benign hyperplasia of the prostate. METHODS:From 1994 to 1998 ultrasound-guided transrectal bi...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章

    doi:

    authors: Herranz Amo F,Verdú Tartajo F,Díez Cordero JM,Leal Hernández F,Bielsa Carrillo A,García Burgos J,Subirá Ríos D

    更新日期:1999-12-01 00:00:00

  • [The results of open surgery in the ureteropelvic junction syndrome].

    abstract:OBJECTIVE:To evaluate the efficacy of the Anderson-Hynes pyeloplasty in 47 patients with pelviureteric junction syndrome and to compare our results with the reported results for open surgery and other techniques. METHODS:The records of 47 patients (21 males, 26 females) with pelviureteric junction syndrome treated at ...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章

    doi:

    authors: Rado Velázquez MA,Portillo Martín JA,Martín García B,Hernández Rodríguez R,Correas Gómez MA,Gutiérrez Baños JL,del Valle Schaan JI,Roca Edreira A,Gutiérrez García R,de Diego Rodríguez E,Hernández Castrillo A

    更新日期:1999-06-01 00:00:00

  • [Nanobacteria and urinary system lithiasis].

    abstract::The presence of microorganisms in certain renal calculi having been demonstrated; currently, there is a debate about the possibility of certain germs of extremely small size, Nanobacteria, which can have an important role in the general theory of lithogenesis. ...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章,评审

    doi:

    authors: García Cuerpo E

    更新日期:2003-03-01 00:00:00

  • [Foreign body as renal pseudotumor in a patient with renal polycystic kidney].

    abstract:OBJECTIVE:To report a case of granuloma due to a retained surgical sponge that mimicked a pseudotumor in a patient with autosomal dominant polycystic kidney disease. The appearance of retained surgical sponges on diagnostic imaging is reviewed. METHODS:Patient evaluation included renal ultrasound, magnetic resonance i...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章

    doi:

    authors: Rebassa Llull MJ,Muñoz Vélez D,Hidalgo Pardo F,Gutiérrez Sanz-Gadea C,Palmer Sancho J,Mus Malleu A,Torrens Darder I,Ozonas Moragues M

    更新日期:2000-11-01 00:00:00

  • [Intrathoracic ectopic kidney in an adult: case report and bibliographic review].

    abstract:OBJECTIVE:We report the case of a 61-year-old male with the incidental diagnosis of intrathoracic renal ectopia during the workup study for a possible lung mass. METHODS:We performed a bibliographic review on the incidence, origin, clinical presentation and diagnosis of this type of renal ectopia. RESULTS:Chest x-ray...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章,评审

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    更新日期:2008-06-01 00:00:00

  • [Antirreflux ureteral catheters.]

    abstract::Double-J ureteral stents disposal is associated with the appearance of side effects in up to 90% of the patients. The main causes of these symptoms are related to stent's design and the materials they are manufactured from. Vesicoureteral reflux and bladder trigone irritation are the etiopathogenic causes of ureteral ...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章,评审

    doi:

    authors: Soria F,de la Cruz JE,Morcillo E,Rioja J,Sánchez-Margallo FM

    更新日期:2016-10-01 00:00:00

  • [Echography, a diagnostic method in testicular abscess].

    abstract::We report on 10 patients who presented with a scrotal mass. The diagnosis of testicular abscess was made on ultrasonographic examination of the scrotal mass. The sensitivity and specificity rates of the foregoing imaging technique were 100%. Furthermore, it permitted determining with precision the extent and degree of...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章

    doi:

    authors: Granados EA,de la Torre P,Alberola J

    更新日期:1991-07-01 00:00:00

  • [Training program on medical urology: Future perspectives.]

    abstract::Urology is defined as the medical-surgical specialty that includes the study, diagnosis and treatment of medical conditions of the urinary system. It is well specified by the National Commission of Specialties that we must know the medical pathology that concerns us. However, on occasions, resident training focuses on...

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章

    doi:

    authors: Gil Moradillo J,Cabrera Meiras F,Alonso Isa M,Lara Isla A,Justo Quintas J,García Rojo E,González Padilla D,García Gómez B,Medina Polo J,Romero Otero J

    更新日期:2018-01-01 00:00:00

  • [Perineo-scrotal gangrene (Fournier's gangrene)].

    abstract::Four cases of perineoscrotal gangrene are reported herein. All were immune-suppressed and three were diabetics. Its primary focus was in the GU tract or intestine. Culture was positive for Gram-negative aerobes and anaerobes. Early aggressive surgery and adjuvant antibiotic therapy achieved an excellent survival rate....

    journal_title:Archivos espanoles de urologia

    pub_type: 杂志文章

    doi:

    authors: Ruiz Rubio JL,Lapuerta Torres E,Bueno Selles C,Martínez Morillas LM,Calatrava Gadea S,Díaz Calleja E,Castillo Gimeno JM

    更新日期:1990-07-01 00:00:00

  • [Cystocele and stress urinary incontinence associated with lower urinary tract obstruction].

    abstract:OBJECTIVES:The association of stress urinary incontinence secondary to urethral hypermobility and lower urinary tract obstruction in the same patient with cystocele is rare, and even represents a contradiction. The objective of our work is to treat to define the characteristics that identify this entity, in comparison ...

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    pub_type: 杂志文章

    doi:10.4321/s0004-06142007000500008

    authors: Salinas J,Prieto S,Adot JM,Virseda M,Silmi A

    更新日期:2007-06-01 00:00:00