Abstract：
:Although numerically far less than claudicants, patients with critical leg ischemia (CLI) demand a disproportionately large commitment both in medical effort and economically and represent the major workload for vascular surgical units. The incidence and prevalence of CLI is approximately 500 to 1,000/million/year. The risk factors for the development of CLI are largely the same as those for the progression of local disease in IC, the most important, apart from age, being smoking and diabetes. Major amputation is more common amongst claudicants who are heavy smokers and who continue to smoke, and although stopping smoking slows down the vascular changes and reduces the likelihood of symptomatic progression, it does not reduce the risk of major amputation over the following 2 to 3 years. Diabetic PAOD patients are about 10 times more likely to come to amputation than nondiabetic PAOD patients, and the prevalence of gangrene is 20 to 30 times higher in individuals with diabetes and PAOD compared with nondiabetics with PAOD. There is some evidence that most of these effects of risk factors are additive.
journal_name
Semin Vasc Surgjournal_title
Seminars in vascular surgeryauthors
Dormandy J,Heeck L,Vig Ssubject
Has Abstractpub_date
1999-06-01 00:00:00pages
138-41issue
2eissn
0895-7967issn
1558-4518journal_volume
12pub_type
杂志文章,评审abstract：:Prophylaxis for venous thromboembolism is an area that has received intense study in certain conditions, but less than adequate coverage in other areas. In considering who needs prophylaxis, patients are categorized into levels of risk. Clinical venous thromboembolism can be correlated to these levels of risk. Methods...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：
更新日期：2000-09-01 00:00:00
abstract：:The development of carotid duplex scanning revolutionized the diagnosis of carotid artery disease. Continued advances in the technology as well as widespread experience with cartoid ultrasound have redefined the role this technology plays in the care of patients with carotid atherosclerosis. Recent clinical trials hav...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：
更新日期：1998-03-01 00:00:00
abstract：:Acute limb ischemia is one of the most potentially devastating but treatable diseases faced by the vascular surgeon. It is crucial to identify the ischemic process early, as the outcomes of early intervention can lead to limb salvage, whereas late recognition places the patient at risk for limb loss and potential mort...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2008.12.004
更新日期：2009-03-01 00:00:00
abstract：:In vascular surgery, the gold standard for evaluation of the lower-extremity arterial tree has long been contrast arteriography (CA). Associated risks of CA are well-documented and include severe allergic reactions, arterial injury and/or hemorrhage, and contrast-induced nephropathy. Increasingly, less-invasive techni...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2007.02.005
更新日期：2007-03-01 00:00:00
abstract：:The size of abdominal aortic aneurysms (AAA) is the most usual predictor of the risk for rupture. Because chronic metalloproteinases production and activation by inflammatory cells causes degradation of elastin and collagen in the aneurysmal wall, the detection of an increased metabolic process preceding fissuration a...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2004.03.002
更新日期：2004-06-01 00:00:00
abstract：:The use of autologous femoral veins for in situ reconstruction of the aortoiliac segment is an effective technique to treat native aorta or prosthetic graft infections. The indications, technical details, and outcomes of this procedure are detailed. Graft infection involving the aortic segment, while rare, remains one...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2019.07.002
更新日期：2019-01-01 00:00:00
abstract：:The increasing availability of and vascular surgeons' familiarity with digital cine-fluoroscopy in the operating room has been facilitated by the advent and growing popularity of endovascular aortoiliac aneurysm repair and other endovascular techniques that are being incorporated into vascular surgical practice. Digit...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2003.08.006
更新日期：2003-12-01 00:00:00
abstract：:Aortoiliac occlusive disease is a significant cause of lower extremity ischemic symptoms. Over the past two decades, most patients have been treated with a variety of surgical procedures, including aortofemoral and extra-anatomic bypasses. Most recently, percutaneous balloon angioplasty and stents have been successful...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：
更新日期：1997-12-01 00:00:00
abstract：:The pathophysiology of the diabetic foot ulcer and soft-tissue infection is due to neuropathy, trauma, and, in many patients, concomitant peripheral artery occlusive disease. Diabetic neuropathy results in foot deformity, leading to increased skin pressure with walking. Once a foot ulcer develops, the limb is at high ...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2019.02.001
更新日期：2018-01-01 00:00:00
abstract：:Constructing vascular access for hemodialysis causes changes in blood flow to the extremity, which can lead to distal ischemia. Ischemic steal syndrome is manifested by pain; weakness; pallor; and, in severe cases, ulceration and tissue loss. Severe ischemia, requiring reintervention, has an incidence of 4%, although ...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2007.07.009
更新日期：2007-09-01 00:00:00
abstract：:Endovascular aneurysm repair has proven to be a valuable alternative to open repair in selected patients. This less invasive procedure, however, requires long-term surveillance for its own set of potential complications, including perigraft leakage, or endoleak. This article focuses on the detection of these leaks, fi...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2004.09.003
更新日期：2004-12-01 00:00:00
abstract：:While carotid angioplasty and stenting has been clearly established as a minimally invasive alternative to endarterectomy for patients with carotid occlusive disease, its indications continue to evolve, being refined as more controlled data of large studies are being accumulated. The purpose of this article is to revi...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2008.03.003
更新日期：2008-06-01 00:00:00
abstract：:Nutcracker syndrome is one of the abdominal venous entrapments, caused by compression of the left renal vein between the superior mesenteric artery and the abdominal aorta. Occasionally a retro-aortic left renal vein is compressed between the aorta and the vertebral body (posterior nutcracker syndrome). The renal vein...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2013.04.006
更新日期：2013-03-01 00:00:00
abstract：:Over the last decade, more than 25,000 endovascular stent grafts have been used to treat aortic aneurysms. Although results have been promising thus far, problems with endoleaks, material failure, device migration, and aneurysm rupture continue to be reported. Improvements in device material and design have contribute...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1016/s0895-7967(03)00006-1
更新日期：2003-06-01 00:00:00
abstract：:Elimination of the embolic potential of existing thrombus, restoration of unobstructed flow, prevention of further thrombosis, and preservation of venous valve function are the ideal goals of therapy for acute deep vein thrombosis (DVT). Meeting these goals will not only prevent pulmonary embolus, but will also minimi...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章
doi：10.1053/j.semvascsurg.2010.10.002
更新日期：2010-12-01 00:00:00
abstract：:The recent endovascular aneurysm repair (EVAR) 1 and 2 and Dutch Randomized Endovascular Aneurysm Management (DREAM) trials addressed management of abdominal aortic aneurysms (AAAs) larger than 5.5 cm in diameter. The DREAM and EVAR 1 trials randomized patients appropriate for open repair between endovascular repair (...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2006.03.001
更新日期：2006-06-01 00:00:00
abstract：:Since carotid endarterectomy was revitalized following the North American Symptomatic Carotid Endarterectomy Trial and Asymptomatic Carotid Atherosclerosis Study, results have improved. However, types of carotid endarterectomy, indications, risk factors, surgical factors, techniques, and other treatment modalities may...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,多中心研究
doi：10.1016/s0895-7967(04)00052-3
更新日期：2004-09-01 00:00:00
abstract：UNLABELLED:A variety of intraoperative imaging and assessment techniques can be used during carotid endarterectomy (CEA) to evaluate the technical results of the arterial repair. However, the necessity of utilizing these techniques routinely in every case, and the actual ability of these studies to improve the outcomes...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2007.10.003
更新日期：2007-12-01 00:00:00
abstract：:The obturator bypass is a useful method for revascularizing the lower extremity in the presence of a hazardous groin dissection. The most common indication for employing this method of reestablishing arterial continuity is in circumventing infected vascular prostheses. One- and 5-year patency rates of 72.7% and 56.9% ...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章
doi：
更新日期：2000-03-01 00:00:00
abstract：:Management of venous ulceration has evolved tremendously during the last 2 decades. There has been considerable progress in our understanding of the pathophysiology, hemodynamics, venous imaging, and therapeutic options for venous ulcers, including endovenous ablation, iliac vein stenting, and vein-valve repair techni...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2015.07.002
更新日期：2015-03-01 00:00:00
abstract：:The etiology of foot lesions in diabetics is multifactorial. Arterial insufficiency, neuropathy, and susceptibility to infection are major factors contributing to the formation of nonhealing diabetic foot lesions. These factors lead to a 15% ulceration rate in diabetics with 20% resulting in amputation. This amputatio...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2012.04.001
更新日期：2012-06-01 00:00:00
abstract：:Patients with end-stage liver disease (ESLD) who develop hepatorenal syndrome (HRS) have very high mortality rates. For patients with HRS type I, median survival without specific therapy is only 2 weeks. Due to worsening clinical condition in such patients secondary to uremia and hepatic disease, some form of renal re...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,meta分析,评审
doi：10.1053/j.semvascsurg.2017.04.001
更新日期：2016-12-01 00:00:00
abstract：:Innovation in medicine is often driven by the observations of imaginative physicians who are blessed with insatiable curiosity, coupled with the inability to accept technical boundaries, the status quo of patient care, or the acceptance of procedural morbidity. Few examples illustrate this truism better than the physi...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2018.03.002
更新日期：2018-03-01 00:00:00
abstract：:Aortic infection is an uncommon but life-threatening condition. Conservative medical treatment is insufficient in many cases because of the high risk of persistent infection, aortic rupture, and death. Conventional open surgical treatment consists of extensive tissue debridement, complete removal of the infected prost...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2011.10.009
更新日期：2011-12-01 00:00:00
abstract：:The failure of an autogenous or prosthetic arteriovenous hemodialysis access is usually related to the failure of the venous outflow resulting from a stenosis somewhere in the venous system, commonly at the venous anastomosis for a prosthetic access or within the central veins. The National Kidney Foundation's Kidney ...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2011.05.008
更新日期：2011-06-01 00:00:00
abstract：:Renal artery stenting remains an important adjuvant treatment for true-resistant hypertension, although recent disappointing randomized trials highlight the importance of careful patient selection. Safe and successful renal interventions begin with critical core knowledge regarding renal artery anatomy and understandi...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2014.06.002
更新日期：2013-12-01 00:00:00
abstract：:Ischemia-reperfusion injury is a continuing challenge to vascular surgeons. Microvascular factors and mechanisms underlying edema and compartment syndrome provide a useful end point for analysis and planning of therapy. We review the pivotal role of endothelium-leukocyte interactions and of cytokines in the genesis of...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：
更新日期：1998-09-01 00:00:00
abstract：:The decision to operate on a patient with an aortic aneurysm is based on the risk of aneurysm rupture versus the risk of aneurysm repair, within the context of the patient's overall life expectancy. Risk of rupture is still primarily based on the maximum aneurysm diameter, with some allowances made for factors that mo...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2007.04.001
更新日期：2007-06-01 00:00:00
abstract：:For generations, the use of techniques to defer skin pressure and protect the lower-extremity wound has been a cardinal goal to achieve therapeutic success and healing. Choosing the appropriate postoperative offloading device or shoe is often difficult, as it is challenging to merge optimal mechanical protection with ...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2014.10.002
更新日期：2014-03-01 00:00:00
abstract：:Recent advances in endovascular technologies have made catheter-based interventions a preferred treatment strategy in patients with intermittent claudication or ischemic rest pain of the lower extremity. Although the current body of literature is inundated with clinical reports favoring countless endovascular devices ...
journal_title：Seminars in vascular surgery
pub_type： 杂志文章,评审
doi：10.1053/j.semvascsurg.2010.05.001
更新日期：2010-09-01 00:00:00
