Risk factors for anastomotic leakage after low anterior resection with total mesorectal excision.

Abstract:

BACKGROUND:This study aims to analyze the risk factors for anastomotic leakage after low anterior resection with the technique of total mesorectal excision (TME). METHODS:From September 1993 to November 1998, 196 patients with rectal cancer from 3 to 12 cm from the anal verge were treated with low anterior resection with TME. The data were entered in a prospective manner, and the factors that might affect anastomotic leakage were analyzed. RESULTS:The mean level of anastomosis was 3.6 cm from the anal verge (range 1 to 5 cm). The leakage rate was 10.2%. Female gender (P = 0.01; 95% confidence interval [CI] 1.3 to 14.3; odds ratio 4.3) and presence of a diversion stoma (P = 0.01; 95% CI 1.4 to 14.2; odds ratio 4.5) were independent significant factors for lower anastomotic leakage. The absence of a stoma was associated with significantly increased leakage in male (P = 0.001) but not in female (P = 0.51) patients. CONCLUSIONS:With low anastomosis after low anterior resection with TME, diversion stoma construction should be performed routinely in men. In women, the need for diversion can be more selective.

journal_name

Am J Surg

authors

Law WI,Chu KW,Ho JW,Chan CW

doi

10.1016/s0002-9610(00)00252-x

subject

Has Abstract

pub_date

2000-02-01 00:00:00

pages

92-6

issue

2

eissn

0002-9610

issn

1879-1883

pii

S000296100000252X

journal_volume

179

pub_type

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