Abstract：
PURPOSE:Temperature increase, oxidative stress, and inflammatory reactions after endurance exercise were expected to stimulate the synthesis of heat shock proteins (HSP) in peripheral blood leukocytes. Furthermore, it was of interest whether regular endurance training influences HSP expression. METHODS:The expression of HSP27, HSP60, HSP70, constitutive HSC70, and HSP90 in the cytoplasma and surface of lymphocytes, monocytes, and granulocytes of 12 trained athletes was analyzed by flow cytometry before and after (0, 3, and 24 h) a half marathon. Twelve untrained persons at rest were included as control. RESULTS:After the race, there was a significantly greater percentage of leukocytes expressing cytoplasmic HSP27, HSP60, and HSP70 (P < 0.01), whereas HSC70 and HSP90 remained unchanged. The fluorescence intensity increased significantly in monocytes for HSP27 (0 and 3 h) and HSP70 (0, 3, and 24 h) and in granulocytes, only 24 h postexercise for HSP70. The percent values of trained athletes at rest were significantly lower compared with untrained persons (P < 0,01). CONCLUSIONS:Strenuous exercise increased HSP expression in blood immediately after the run, indicating a protective function of HSP in leukocytes of athletes to maintain function after heavy exercise. The downregulation of HSP-positive cells in trained athletes at rest seems to be a result of adaptation mechanisms to regular endurance training.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Fehrenbach E,Passek F,Niess AM,Pohla H,Weinstock C,Dickhuth HH,Northoff Hdoi
10.1097/00005768-200003000-00007subject
Has Abstractpub_date
2000-03-01 00:00:00pages
592-600issue
3eissn
0195-9131issn
1530-0315journal_volume
32pub_type
杂志文章abstract：BACKGROUND:For optimal health benefits, moderate- to vigorous-intensity physical activity (MVPA) is recommended in sustained bouts lasting ≥10 min. However, short spurts of MVPA lasting <10 min are more common in everyday life. It is unclear whether short spurts of MVPA further protect against the development of hypert...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000662
更新日期：2015-11-01 00:00:00
abstract：PURPOSE:This study aimed to determine whether competitive intermittent exercise in the heat affects recovery, aggravates markers of muscle fiber damage, and delays the recovery of performance and muscle glycogen stores. METHODS:Plasma creatine kinase, serum myoglobin, muscle glycogen, and performance parameters (sprin...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31827ded04
更新日期：2013-05-01 00:00:00
abstract：:The assumption that lower extremity function is bilaterally symmetrical is prevalent throughout the biomechanics literature. The unilateral development of many overuse and acute injuries may suggest that this assumption is inaccurate. Analyses of bilateral function report conflicting results and may be partially attri...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1994-09-01 00:00:00
abstract：:The downswing phase in golf was represented as a double pendulum pivoted at the shoulder joint and hinged at the wrist. The motion of such a pendulum was used to derive a series of equations which were used to describe the instantaneous values of several of the component features of the downswing. Results of this anal...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/00005768-198201000-00012
更新日期：1982-01-01 00:00:00
abstract：:Ten pairs of monozygotic twins of both sexes were submitted to a 20-wk endurance-training program, four and five times per week, 40 min per session, at an average of 80% of the maximal heart rate reserve. Testing and training were performed on cycle ergometers. Maximal aerobic power (MAP in ml O2 X min-1 X kg-1) and v...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/00005768-198410000-00012
更新日期：1984-10-01 00:00:00
abstract：PURPOSE:Compare three published methods of quantifying physical activity (total activity, peak strain, and bone-loading exposure (BLE) scores) and identify their associations with areal bone mineral density (aBMD), volumetric BMD (vBMD), and bone strength. METHODS:Postmenopausal women (N = 239; mean age: 53.8 yr) from...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,多中心研究
doi：10.1249/mss.0b013e318155a7fe
更新日期：2007-12-01 00:00:00
abstract：PURPOSE:The purpose of this study was to examine the relative association of physical activity, cardiorespiratory fitness (CRF), and adiposity with C-reactive protein (CRP) in prepubescent children. METHODS:Forty-five prepubescent children (age = 9.4 ± 1.6 yr; 26 boys) were assessed for adiposity (percent fat) via dua...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181e0355e
更新日期：2010-11-01 00:00:00
abstract：PURPOSE:We aimed to evaluate in a longitudinal study the effect of intensive training on cardiac autonomic control in athletes using 24-h heart rate variability analysis. METHODS:Time and frequency domain measures of heart rate variability were calculated from 24-h Holter monitoring in 15 high level bicyclists (mean a...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199805000-00008
更新日期：1998-05-01 00:00:00
abstract：:The relationships between physical activity, physical fitness, and coronary heart disease risk factors measured in a large community sample were evaluated. Self-reported physical activity using a single question, maximal oxygen consumption estimates derived from the Pawtucket Heart Health Step Test, blood pressure, no...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：:Increased vertical impact loading during running has been associated with a variety of running related injuries including stress fractures, patellofemoral pain, and plantar fasciitis. PURPOSE:The purpose of this study was to examine the acute and long-term effect of a gait retraining program aimed at teaching runners...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000001710
更新日期：2018-12-01 00:00:00
abstract：PURPOSE:To examine the influence of two patellofemoral braces on pain response, patellar alignment, and patellofemoral joint contact area in persons with patellofemoral pain. METHODS:Fifteen women between the ages of 18 and 45 yr with a diagnosis of patellofemoral pain participated. After the assessment of pain respon...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.mss.0000132376.50984.27
更新日期：2004-07-01 00:00:00
abstract：PURPOSE:To determine the prevalence of reversible airway obstruction in a group of professional football training camp participants. METHODS:All attendees at a Canadian Football League team rookie preseason training camp were invited to participate in a protocol designed to elicit symptoms and signs of reversible airw...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200012000-00003
更新日期：2000-12-01 00:00:00
abstract：:Magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) are new and powerful tools to study tissue biochemistry, and to provide precise anatomical visualization of soft tissue structures. This review focuses on the use of these techniques to study exercise-induced muscle injury. MRS measurements sho...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：
更新日期：1992-05-01 00:00:00
abstract：PURPOSE:To investigate the effects of blood flow restriction (BFR) combined with electrical muscle stimulation (EMS) on skeletal muscle mass and strength during a period of limb disuse. METHODS:Thirty healthy participants (22 ± 3 years; 23 ± 3 kg·m) were randomly assigned to either: control (CON; n=10), BFR alone (BFR...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002544
更新日期：2020-10-22 00:00:00
abstract：PURPOSE:High school cross-country runners have a high incidence of injury, particularly at the shin and knee. An increased step rate during running has been shown to reduce impact forces and loading of the lower extremity joints. The purpose of this prospective study was to examine step rate as a risk factor for injury...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000890
更新日期：2016-07-01 00:00:00
abstract：UNLABELLED:Nampt/pre-B-cell colony-enhancing factor/visfatin (visfatin) release from adipocytes has recently been suggested to be nutrient responsive and linked to systemic nicotinamide adenine dinucleotide biosynthesis and regulation of pancreatic beta-cell function. PURPOSE:We hypothesized that if visfatin does play...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e318195bad5
更新日期：2009-06-01 00:00:00
abstract：PURPOSE:Cardiac aldosterone might be involved in the deleterious effects of nandrolone decanoate (ND) on the heart. Therefore, we investigated the involvement of cardiac aldosterone, by the pharmacological block of AT1 or mineralocorticoid receptors, on cardiac hypertrophy and fibrosis. METHODS:Male Wistar rats were r...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e318217e8b6
更新日期：2011-10-01 00:00:00
abstract：PURPOSE:There is a lack of robust evidence to support a daily step count target that equates to current physical activity guidelines in children and youth. This information would be useful to researchers and practitioners who are using pedometers to monitor physical activity. METHODS:Accelerometer and pedometer data c...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31823f23b1
更新日期：2012-05-01 00:00:00
abstract：PURPOSE:Despite endorsement by various health organizations, there is a lack of research on the effectiveness of perceptually regulated exercise training (PRET) as a method of exercise intensity prescription. The purpose of this study was to confirm the efficacy of an 8-wk PRET program clamped at RPE13 to improve aerob...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0b013e31824d266e
更新日期：2012-08-01 00:00:00
abstract：PURPOSE:Apnea divers hyperinflate the lung by taking a deep breath followed by glossopharyngeal insufflation. The maneuver can lead to symptomatic arterial hypotension. We tested the hypotheses that glossopharyngeal insufflation interferes with cardiac function further reducing cardiac output (CO) using cardiac magneti...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31821ff294
更新日期：2011-11-01 00:00:00
abstract：:Muscle force can be transmitted via connective tissues to neighboring muscles. The goal of this research is to determine the extent to which this effects force summation between synergists during physiological conditions. This manuscript reviews two studies examining the interaction between synergists in cat hindlimb....
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：10.1249/MSS.0b013e318183c0c3
更新日期：2009-01-01 00:00:00
abstract：PURPOSE:Development of an endurance training-overtraining protocol for Wistar rats that includes increased workload and is characterized by analyses of performance and biomarkers. METHODS:The running protocol lasted 11 wk: 8 wk of daily exercise sessions followed by 3 wk of increasing training frequency (two, three, a...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e318191259c
更新日期：2009-05-01 00:00:00
abstract：:The individual anaerobic threshold (IAT) is the highest metabolic rate at which blood lactate (LA) concentrations are maintained at a steady state during prolonged exercise. The purpose of this study was to compare the effects of active and passive recovery on the determination of the IAT before and after an endurance...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章
doi：
更新日期：1989-10-01 00:00:00
abstract：:Maximal lactate steady state (MLSS) refers to the upper limit of blood lactate concentration indicating an equilibrium between lactate production and lactate elimination during constant workload. The aim of the present study was to investigate whether different levels of MLSS may explain different blood lactate concen...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199602000-00013
更新日期：1996-02-01 00:00:00
abstract：PURPOSE:To determine whether lactate profiling could detect changes in discrete aspects of endurance fitness in world-ranked swimmers during a season. METHODS:Eight male and four female Australian National Team swimmers aged 20--27 yr undertook a 7 x 200-m incremental swimming step test on four occasions over an 8-mon...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200102000-00019
更新日期：2001-02-01 00:00:00
abstract：PURPOSE:Muscle sympathetic nerve activity (MSNA) is increased in older endurance-trained men, yet the reflex sympathetic forearm vasoconstrictor response to graded lower body negative pressure (LBNP) diminishes with age. The aim of this study was to assess the influence of aerobic exercise capacity on this altered neur...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31822a68a5
更新日期：2012-02-01 00:00:00
abstract：INTRODUCTION:Regular exercise can reduce the risk of developing cardiovascular disease through risk factor modification, with high-intensity exercise and more recently small muscle mass training providing alternatives to moderate-intensity exercise. METHODS:This study randomly assigned 53 healthy middle-age adults (ag...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1249/MSS.0000000000002053
更新日期：2019-11-01 00:00:00
abstract：PURPOSE:To determine whether the magnitude of improvement in athletic performance and the mechanisms driving these adaptations differ in relatively weak individuals exposed to either ballistic power training or heavy strength training. METHODS:Relatively weak men (n = 24) who could perform the back squat with proficie...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0b013e3181d2013a
更新日期：2010-08-01 00:00:00
abstract：UNLABELLED:A new accelerometer, the Kenz Lifecorder EX (LC; Suzuken Co. Ltd, Nagoya, Japan), offers promise as a feasible monitor alternative to the commonly used Actigraph (AG: Actigraph LLC, Fort Walton Beach, FL). PURPOSE:This study compared the LC and AG accelerometers and the Yamax SW-200 pedometer (DW) under fre...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/mss.0b013e3180313056
更新日期：2007-04-01 00:00:00
abstract：INTRODUCTION:It is well established that hemodynamic dysfunction, resulting in diminished upper-extremity work capacity, occurs in persons with spinal cord injury (SCI) as compared with those who are nondisabled (ND). Although it has been shown that persons with paraplegia display higher values of heart rate (HR) with ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200209000-00001
更新日期：2002-09-01 00:00:00
