Abstract：
OBJECTIVE:To quantitatively assess the antispastic effect of intrathecally administered baclofen on muscle stiffness in spastic patients. DESIGN:Case-control study. SETTING:Clinical laboratory in a university hospital of a city of more than 1,000,000 inhabitants. PARTICIPANTS:Eighteen healthy adult volunteers (9 men, 9 women) were recruited for establishing the normal values. Eleven spastic patients (8 men, 3 women) comprised the study group. MAIN OUTCOME MEASURES:The resistance to passive sinusoidal displacement of 5 degrees imposed to the ankle joint was measured at frequencies from 3 to 12 Hz. Torque and displacement signals were subjected to a Fourier analysis to isolate the elastic and viscous components of the total muscle stiffness. RESULTS:In comparison with the period before intrathecal injection, and with the control group, it was shown that at 4 hours after injection, stretch reflex activity was abolished and elastic and viscous muscle stiffness approached control values. The abnormal residual stiffness concerned only the elastic component due to chronic transformations of the spastic muscle and/or due to changes in joints and periarticular connective tissue. This antispastic effect was completely reversed 36 hours after injection. CONCLUSION:The present study shows that the antispastic effect of intrathecally administered baclofen in spastic patients can be quantitatively assessed by a sensitive method allowing measurement of elastic and viscous components of muscle stiffness.
journal_name
Arch Phys Med Rehabiljournal_title
Archives of physical medicine and rehabilitationauthors
Detrembleur C,Plaghki Ldoi
10.1016/s0003-9993(00)90071-6subject
Has Abstractpub_date
2000-03-01 00:00:00pages
279-84issue
3eissn
0003-9993issn
1532-821Xpii
S0003-9993(00)90071-6journal_volume
81pub_type
杂志文章abstract：:This study examined the validity and reliability of the anaerobic threshold (AT) using blood lactate (ATLa) and respiratory gas exchange (ATg) criteria during cycle ergometry (CE) and wheelchair ergometry (WE) in athletes with spastic cerebral palsy (CP). Eleven subjects attempted a discontinuous incremental test prot...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1993-03-01 00:00:00
abstract：OBJECTIVES:To determine whether the measurement properties of the Mayo-Portland Adaptability Inventory Version 4 (MPAI-4) and its participation index (M2PI), which have been adopted as 2 outcome measures in the Veterans Health Administration (VHA) National Polytrauma Rehabilitation Systems of Care, are adequate in vete...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2019.10.191
更新日期：2020-05-01 00:00:00
abstract：:Despite the rapid growth in the number of rehabilitation specialty hospitals in recent years, there is little knowledge of the performance of these facilities. The recent growth in the number of for-profit rehabilitation providers and increasing competition among for-profit and not-for-profit rehabilitation hospitals ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/s0003-9993(95)80569-9
更新日期：1995-05-01 00:00:00
abstract：:This retrospective study examined the effects of type of payor (ie, catastrophic, Medicaid, and private) and extent of benefits and independent living (IL) resources received on functional and psychosocial outcomes after spinal cord injury (SCI). One hundred seventy SCI persons with dates of injury from 1985 to 1990 a...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/0003-9993(94)90164-3
更新日期：1994-04-01 00:00:00
abstract：OBJECTIVES:To investigate the links between resilience and depressive symptoms, social functioning, and physical functioning in people aging with disability and to investigate the effects of resilience on change in functional outcomes over time. DESIGN:Longitudinal postal survey. SETTING:Surveys were mailed to a comm...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2015.02.023
更新日期：2015-07-01 00:00:00
abstract：:A study of body composition was conducted on 45 patients with spinal cord injury (SCI) and 12 able-bodied healthy subjects who served as controls. Body composition was assessed in terms of water (W), fat (F), protein (P), and mineral (M) content. SCI patients exhibited lower absolute amounts of W, F, and P, but no dif...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/0003-9993(85)90167-4
更新日期：1985-04-01 00:00:00
abstract：OBJECTIVE:To examine for differences in joint position sense (JPS) between knees with reconstructed anterior cruciate ligaments (ACLs) and uninjured knees by using a functional weight-bearing measurement method. DESIGN:Two-way repeated-measures in a convenience sample. SETTING:An Australian university rehabilitation ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/s0003-9993(03)00007-8
更新日期：2003-06-01 00:00:00
abstract：:Four patients with end-stage renal failure on maintenance hemodialysis and one patient with near end-stage renal failure received inpatient rehabilitation following lower extremity amputation. All were prosthetically restored. Three of the patients had bilateral below-knee amputations and were ambulatory at the time o...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1986-05-01 00:00:00
abstract：OBJECTIVE:To compare the efficacy of 2 group treatments for persons with brain injury (BI) and their caregivers in promoting perceived self-efficacy (PSE) and emotional and neurobehavioral functioning. DESIGN:Randomized controlled trial. SETTING:Outpatient BI rehabilitation. PARTICIPANTS:Subjects (N=38), including 1...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.apmr.2015.10.097
更新日期：2016-02-01 00:00:00
abstract：OBJECTIVE:To determine the most reliable method to measure the length of the radial nerve during a nerve conduction study (NCS). DESIGN:Cadaveric investigation. SETTING:A practical anatomy research laboratory in a university. PARTICIPANTS:Fresh cadavers (N=10), with 1 cadaver for study design and 9 for data. INTERV...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2016.08.464
更新日期：2017-03-01 00:00:00
abstract：OBJECTIVE:To examine whether, in patients with carpal tunnel syndrome (CTS), electrodiagnostic study findings were associated with patient symptom severity and functional limitations after controlling for potentially confounding variables including depression, somatization, and pain-related catastrophizing. DESIGN:Cro...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2006.10.013
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVE:To compare results of the observational Wisconsin Gait Scale (WGS) and global gait indexes such as Gait Deviation Index (GDI) and Gait Variability Index (GVI), constituting an objective method of assessing gait, and taking into account parameters identified during 3-dimensional gait analysis (3DGA). DESIGN:A...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2018.12.031
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVE:To assess different aspects of sexual function in men with spinal cord injury (SCI) using the Male Sexual Quotient (MSQ), a newly developed tool to assess sexual function and satisfaction. DESIGN:Cross-sectional study. SETTING:Tertiary rehabilitation center. PARTICIPANTS:Patients (N=295) older than 18 year...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2016.01.005
更新日期：2016-06-01 00:00:00
abstract：:Twenty-nine C4 to C7 motor-complete spinal cord injured subjects were evaluated to determine whether the manual muscle test (MMT) performed within 24 hours of injury or at 72 hours after injury better predicts short-term functional muscle recovery. A single muscle in the zone of injury that had a muscle grade between ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1991-07-01 00:00:00
abstract：OBJECTIVE:To evaluate whether adding functional exercise training to standard physiotherapy during residential slow-stream rehabilitation (SSR) improves discharge outcomes and functional ability. DESIGN:Randomized controlled trial. SETTING:A regional hospital. PARTICIPANTS:Older people (N=60) admitted to SSR. INTER...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.apmr.2014.12.012
更新日期：2015-05-01 00:00:00
abstract：OBJECTIVE:To determine the association of various symptoms and psychiatric diagnoses with a remote history of mild traumatic brain injury (MTBI) and a current diagnosis of posttraumatic stress disorder (PTSD). DESIGN:Cross-sectional cohort study. SETTING:Nonclinical. PARTICIPANTS:Three groups of randomly selected co...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2009.01.023
更新日期：2009-07-01 00:00:00
abstract：:Sixty patients with spinal muscular atrophy (SMA) are presented. Although the life span with Type I SMA (Werdnig-Hoffmann disease) may be short, children with the disease can be made more comfortable with appropriate medical care and parental support. Despite electrodiagnostic findings which are not always pathognomon...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1984-09-01 00:00:00
abstract：:Power wheelchair (PWC) users depend on their equipment to reliably transport them throughout daily activities and allow them to participate fully in community life. However, as reported by Worobey and colleagues, PWCs frequently require repairs and cause users a variety of problems, which can range from annoying to ca...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 评论,杂志文章
doi：10.1016/j.apmr.2014.01.002
更新日期：2014-04-01 00:00:00
abstract：:Fifty-six shoulders in 50 patients with adhesive capsulitis were divided into 2 groups, using different treatment programs. Group A comprised 28 shoulders in 26 patients. These were treated by therapeutic heating modalities followed by therapeutic exercises and gentle rhythmic stabilization manipulation. Group B total...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:In this cross-sectional study, the bone mineral density of the lumbar spine, the back extensor strength, and the level of physical activity were determined in 68 healthy, postmenopausal women. Physical activity was determined by a graded questionnaire and varied from sedentary to heavy vocational and avocational activ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1988-04-01 00:00:00
abstract：OBJECTIVE:To examine the effects of skill training on swallowing in individuals with dysphagia secondary to Parkinson's disease (PD) and to explore skill retention after treatment termination. DESIGN:Within-subject pilot study with follow-up after 2 weeks of treatment and after a 2-week nontreatment period. SETTING:C...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2014.03.001
更新日期：2014-07-01 00:00:00
abstract：OBJECTIVE:To investigate the relationship between pushrim forces and the progression of shoulder injuries in manual wheelchair users. DESIGN:Longitudinal case series. SETTING:Biomechanics laboratory and magnetic resonance imaging (MRI) facility at a Veterans Health Administration medical center and university hospita...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1053/s0003-9993(03)00282-x
更新日期：2003-11-01 00:00:00
abstract：OBJECTIVE:Rearfoot motion, particularly rearfoot pronation, has been associated with many foot and leg pathologies. The assessment of abnormal rearfoot pronation frequently involves the use of video assessment in both clinical and research settings, but the reliability of this assessment has not been addressed. DESIGN...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/s0003-9993(96)90003-9
更新日期：1996-07-01 00:00:00
abstract：OBJECTIVES:To compare the effects of biofeedback with those of active exercise and passive treatment in treating work-related neck and shoulder pain. DESIGN:A randomized controlled trial with 3 intervention groups and a control group. SETTING:Participants were recruited from outpatient physiotherapy clinics and a loc...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.apmr.2010.12.037
更新日期：2011-06-01 00:00:00
abstract：OBJECTIVE:To examine the reliability, convergent, and discriminant validity of the limits of stability (LOS) test to assess dynamic postural stability in adolescents using a portable forceplate system. DESIGN:Cross-sectional reliability observational study. SETTING:School setting. PARTICIPANTS:Adolescents (N=36) com...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2015.08.418
更新日期：2015-12-01 00:00:00
abstract：:There continues to be considerable confusion and controversy on the use of diagnostic and clinical terms assigned to patients with severe alterations in consciousness. This confusion results largely from the lack of a uniform classification system that is based on behaviorally defined criteria. This position paper pro...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/s0003-9993(95)80031-x
更新日期：1995-02-01 00:00:00
abstract：OBJECTIVE:To test a functional electric stimulation (FES)-assisted exercise therapy system for improvement of motor function of the hemiplegic upper extremity. DESIGN:A before-after trial, with 2-month follow-up. SETTING:A university research laboratory. PARTICIPANTS:A convenience sample of 6 subjects (3 men, 3 wome...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 临床试验,杂志文章
doi：10.1016/j.apmr.2003.08.094
更新日期：2004-06-01 00:00:00
abstract：OBJECTIVE:To examine the effect of different levels of fractional inspired oxygen (FiO(2)) (15%, 21%, 50%) on peak oxygen consumption (VO(2)peak) during arm exercise in persons with spinal cord injury and in able-bodied controls. DESIGN:Case-control study. SETTING:University medical center in the Netherlands. PARTIC...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2003.02.001
更新日期：2004-02-01 00:00:00
abstract：OBJECTIVE:To assess the relationship between foot pressures measured during level walking and other types of ambulatory activity in subjects with diabetes mellitus (DM) and peripheral neuropathy (PN). DESIGN:Descriptive survey with repeated measures. SETTING:University medical center. PARTICIPANTS:Convenience sample...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2003.06.004
更新日期：2004-02-01 00:00:00
abstract：:The degree to which physical therapists correctly predicted motor and functional outcome for stroke patients was investigated. Therapists used an adapted form of the physical therapy portion of the Patient Evaluation Conference System (PECSc)--a 14-item assessment measured on an 8-point scale. At admission to a rehabi...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1989-02-01 00:00:00
