Abstract:
OBJECTIVES:To explore the links between the histological composition of the prostate and the symptoms related to the clinical BPH. MATERIAL & METHODS:The prostates of 34 patients with symptoms of BPH and 17 asymptomatic patients were biopsied. Using light microscopy, the ratio of stromal to glandular surfaces was calculated. The main dimensions of 5 epithelial cells randomly selected, were examined under electron microscopy in each case. The number and length of microvilli, and the number of secretory granules were determined. The results of symptomatic and asymptomatic subjects were compared by means of Student's t and Mann-Whitney's U tests. RESULTS:The mean ratio of stromal and glandular surfaces came to 4:1 and 6.5:1 in the symptomatic and asymptomatic patients, respectively. The difference was not statistically significant (p = 0.18). Although the average cellular surface of the symptomatic patients was inferior to that of the asymptomatic subjects (74 and 88 mu2. respectively), the differences did not reach statistical significance (p = 0.14). Similarly, the mean nuclear surface of the symptomatic and asymptomatic patients (19.5 and 20.8 mu2, respectively) did not differ (p = 0.48). No differences were detected in the number of secretory granules and microvilli, nor in the length of the microvilli. CONCLUSIONS:The occurrence of symptoms related to the clinical BPH is not due to differences in the composition of the prostate. No clear links seem to exist between the structural changes in the epithelial cells and the development of symptoms. Considering the proportions of epithelium and stroma, therapy focused in the prostatic stroma should yield the best results.
journal_name
Actas Urol Espjournal_title
Actas urologicas espanolasauthors
Páez Borda A,Luján Galán M,Martín Osés E,de la Cal MA,García M,Martín-Benito J,Barba C,Berenguer Sánchez Asubject
Has Abstractpub_date
1999-06-01 00:00:00pages
518-22issue
6eissn
0210-4806issn
1699-7980journal_volume
23pub_type
杂志文章abstract:OBJECTIVE:To asses the prognostic value of deoxyribonucleic acid (DNA) ploidy in a group of patients with prostate cancer treated with adrogenic blockade. MATERIALS AND METHODS:A retrospective study on 136 patients with prostatic cancer having undergone androgenic blockade was carried out. The prognostic influence of ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(01)72616-2
更新日期:2001-04-01 00:00:00
abstract::We report a strange case of a bladder whose first metastasic manifestation, after two years of the diagnosis, was a peripheric polyneuropathia. This patient was treated with immunotherapy with BCG for superficial carcinoma of the bladder during one year. Gradually central neurological symptoms appeared and the patient...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(99)72387-9
更新日期:1999-11-01 00:00:00
abstract:INTRODUCTION:Primary adenocarcinoma of the seminal vesicle is an extremely rare condition. Some cases have been described in relation to congenital seminal vesicle cysts, which is often also associated with agenesia or ipsilateral renal disgenesia. The rareness of this type of lesions makes it difficult to plan a regul...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/j.acuro.2011.01.007
更新日期:2011-05-01 00:00:00
abstract::The hernia of the bladder in the scrotum is a highly uncommon observation. From the clinical standpoint the usual manifestation is a two-stroke voiding. The recommended urological examinations to reach a diagnosis are ultrasound, endovenous urography, retrograde urethrocystography and cystoscopy. Management includes t...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:
更新日期:1999-01-01 00:00:00
abstract::Case report of a patient bearer of a double-J ureteral catheter due to ureteral lithiasis. After persistent renoureteral pain and fever, the proximal migration of the catheter is confirmed radiologically. The predisposing factors for this complication, described in the literature, are reviewed. ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:
更新日期:1997-04-01 00:00:00
abstract:OBJECTIVE:To analyze the incidence of urological complications, like fistula and stenosis in our series of 282 renal transplants and their management. MATERIALS AND METHODS:Between December 1995 and October 2005, 282 adult recipients underwent renal transplant. The most common urological complication was urinary fistu...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(06)73503-3
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVE:To determine the values of PSA in Spanish workers without history of prostate problems and compare them with other geographical latitudes. METHODS:Observational, retrospective, multicenter and population-based study, conducted between January 1 and December 31, 2006. A total of 65303 workers participated in ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,多中心研究
doi:
更新日期:2010-09-01 00:00:00
abstract::Presentation of one case of vesical nephrogenic adenoma diagnosed as an accidental histological finding following TUR of vesical tumour. This case if considered of interest due to the rarity of the lesion (some 300 cases reported) and the limited number of quotations in the Spanish literature. ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:
更新日期:1992-10-01 00:00:00
abstract::Contribution of a case report of megacalycosis in a nine and a half-year old male child, in whom the disorder was diagnosed by our team when he was only four. The intense colic pains experienced by the child together with the isotopic renogram non responsive to seguril typical of obstruction, raised the diagnosis of s...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1997-03-01 00:00:00
abstract::Given the nature of the multiple causes of male infertility, some of them are «reversible» and can be managed with a surgical procedure to recover, in some cases, the fertilizing capacity of the male reproductive tract. With appropriate use of diagnostic tools and clinical judgement, the physician can identify the ide...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:10.1016/j.acuro.2019.10.012
更新日期:2020-06-01 00:00:00
abstract::Report of a 32-year old male patient with an injury of the posterior urethra caused by firearm. Initial examination only revealed fracture of the femoral vein. Absence of spontaneous micturition during the immediate post-operative made necessary to undertake retrograde urethrography, in which a fracture of the posteri...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1995-04-01 00:00:00
abstract::Contribution of two cases of congenital adrenal hyperplasia by blockade in the 21-hydroxylase enzyme synthesis. Diagnosis was reached from the clinical signs and symptoms (virilization syndrome), and was confirmed by radiological and laboratory tests. Hormone treatment was done with hydrocortisone and fludrocortisone,...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1995-02-01 00:00:00
abstract::In Spain, based on the IIEF, 19% of males between 25 and 70 years old present some degree of erectile dysfunction (ED). Therefore, around 2,000,000 Spanish men present this condition and could require medical attention for it. Here, we present an up-date of the most important aspects of erectile dysfunction (pathophys...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:10.1016/s0210-4806(02)72844-1
更新日期:2002-10-01 00:00:00
abstract::We report a case of necrotizing granulomatous vasculitis in the spermatic cord in a 35-year-old man with an antecedent of brain stroke 3 years before. The clinical manifestation was as a painless left scrotal mass. The diagnosis was established by histological examination of the spermatic cord. We discuss the physical...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(05)73340-4
更新日期:2005-09-01 00:00:00
abstract::Appearance of orbital metastatic (OM) neoplasia is the most frequent cause of eye tumour; however, its incidence related to prostatic carcinoma (PC) is rare, primarily when there is sole infiltration of the periorbital soft tissue (STOM). The paper describes the case of a patient diagnosed with PC presenting proptosis...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract::Stones with different compositions respond differently to shock wave lithofragmentation. Likewise, the various lithotrity systems used may have different effects on the stones. To determine the relationships between stone composition and their fragmentation patterns, we conducted an in vitro study using endoscopy, mag...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract::Presentation of four cases of keratinizing squamous metaplasia (KSM), two of the renal pelvis, one pyelocaliceal and one ureteral. Nephrouretetectomy was performed in all cases. All our patients showed good evolution. A review of the literature is made discussing all the etiological, diagnostic and therapeutical aspec...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:
更新日期:1994-09-01 00:00:00
abstract:OBJECTIVES:To perform the linguistic and psychometric validation of the Spanish version of the BSW (Benefit, Satisfaction and Willingness to continue) questionnaire. MATERIAL AND METHODS:Epidemiologic, observational, multicenter, prospective (October 2008-February 2009) study in patients ≥40 years old with de novo ove...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,多中心研究
doi:10.1016/j.acuro.2013.03.005
更新日期:2013-09-01 00:00:00
abstract:CONTEXT:Despite being a validated source of biomarkers, liquid biopsy has not yet succeeded in becoming part of the standard clinical practice in prostate cancer patients. Few biomarkers undergo adequate validation, prospective and independent, of their predictive and/or prognostic value, which results in a lack of the...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,评审
doi:10.1016/j.acuro.2019.08.007
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVES:To disclose the features of bladder cancer in current smokers at diagnosis and to study the differences in recurrence and progression between smokers and non-smokers. PATIENTS & METHODS:786 consecutive patients with bladder cancer from 1991 to 2004 were studied in a retrospective manner and characteristics ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(07)73648-3
更新日期:2007-04-01 00:00:00
abstract::The microscopic patterns adopted by prostate carcinomas are extraordinarily variable making its histopathological classification and grading extremely complicated. There are numerous systems for prostatic tumours' grading, but many of them lack a truly reproducible character and an acceptable degree of reliability; fo...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1992-09-01 00:00:00
abstract::Contribution of one case of prostate cancer presenting with a large abdominal mass associated to anaemia and weight loss. Serum PSA level was greater than 10,000 ng/mL. Imaging studies showed large retroperitoneal mass that led to other differential diagnoses. Biopsy revealed findings suggestive of adenocarcinoma with...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/s0210-4806(99)72377-6
更新日期:1999-10-01 00:00:00
abstract::Some feasibility problems were detected during the evaluation of the IPSS questionnaire in Spanish that might limit its application. Our initial experience with the IPSS in patients undergoing surgery had 3 aims: 1) assess if changes in format and wording will improve feasibility; 2) evaluate symptoms before and after...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1995-03-01 00:00:00
abstract::Presentation of three cases of haemodialysis patients with acquired cystic renal disease (ACRD) who, over the course of their illness, developed clear cells renal carcinoma. The paper emphasizes the common association of these two entities and the need to consider ACRD cases as patients at high risk of developing rena...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1992-07-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVES:The study was conducted to identify the risk factors of upper tract stone formation in patients with diversions after radical cystectomy (RC). MATERIALS AND METHODS:All patients with diversion after RC were collected in our center from January 2005 to December 2013. Three different common d...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/j.acuro.2019.04.002
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVES:The functional symptoms of the filling phase and detrusor overactivity are two inter-related dysfunctions of the lower urinary tract. We have aimed to study the participation of the lesion of the pudendal nerve in both urinary dysfunctions. MATERIAL AND METHODS:A cross-sectional cutoff study in a series of ...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/j.acuro.2011.07.011
更新日期:2012-01-01 00:00:00
abstract:GOALS:To estimate the prevalence, age distribution, impact on quality of life and type of urinary incontinence (UI) in women over 30 years in Mallorca (Spain). MATERIAL AND METHODS:Cross-sectional descriptive study on a randomized sample of 673 women in the health district affiliated to Son Llàtzer Hospital and the 14...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章,多中心研究
doi:10.1016/j.acuro.2012.11.004
更新日期:2013-06-01 00:00:00
abstract::Retrocaval ureter is a rare disease in childhood which is due to a abnormal development of the inferior cava vein. We report a new case of retrocaval ureter in a 9 year-old girl who had consulted for macrohematuria and right flank pain. Preoperative intravenous urography and DTPA diuretic renogram suggested this entit...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1998-10-01 00:00:00
abstract::Presentation of a retrospective study in 227 lithiasic patients with indication for extracorporeal lithotrity (ESWL) as first line of therapy or as adjuvant treatment, referred to three lithotripter units over the last five years. There was a high percentage of personal history of lithiasis (55.5%), colic pain being t...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract:INTRODUCTION:primary hyperaldosteronism is one of the few potentially curable causes of secondary arterial hypertension. One of the most important variants is the adenoma of the adrenal cortex that produces aldosterona (Conn's Syndrome). The treatment of choice in this subgroup of patients was the removal of the lesion...
journal_title:Actas urologicas espanolas
pub_type: 杂志文章
doi:10.1016/j.acuro.2010.11.009
更新日期:2011-02-01 00:00:00