Immunohistochemical localization of collagen VI in arthrofibrosis.

Abstract:

:Arthrofibrosis is a disabling complication after knee trauma and surgery. Clinically, it is characterized by pain and joint stiffness due to massive connective tissue proliferation. In similar pathological conditions with fibrotic transformation such as lung fibrosis or superficial fibromatoses, an increased expression of collagen type VI has been reported. Collagen VI, which forms a filamentous network, is thought to serve as an anchoring element between collagen I/III fibrils and basement membranes and as a cell binding structure. Collagen VI may also play a contributing role in the pathogenesis of arthrofibrosis. The aim of the present study was therefore to demonstrate the localization and distribution of type VI collagen in arthrofibrotic tissue. Tissue samples from the infrapatellar fat pad and intercondylar synovia of 13 patients suffering from arthrofibrosis were taken at surgery. The expression of type VI collagen was studied immunohistochemically using an immunoperoxidase method for light microscopic visualization. Histologic analysis showed a synovial hyperplasia with inflammatory cell infiltration and vascular proliferation. Compared with normal synovial tissue, type VI collagen was widely distributed as a network subsynovially and around the capillary walls. The results of the present study suggest that dysregulation of collagen VI synthesis could be an important contributing factor in the complex mechanisms of disordered matrix protein deposition leading to arthrofibrosis.

authors

Zeichen J,van Griensven M,Albers I,Lobenhoffer P,Bosch U

doi

10.1007/s004020050417

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

315-8

issue

5-6

eissn

0936-8051

issn

1434-3916

pii

91190315.402

journal_volume

119

pub_type

临床试验,杂志文章
  • Surgical reconstruction for chronic painful acromioclavicular joint dislocations.

    abstract:INTRODUCTION:We reviewed the results of modified Weaver-Dunn procedure in patients with persistent painful shoulder following acromioclavicular joint dislocations. MATERIALS AND METHODS:Modified Weaver-Dunn procedure using of mersilene tape was done. There were 15 patients with Rockwood type III injury. The mean age a...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-007-0298-7

    authors: Kumar S,Penematsa SR,Selvan T

    更新日期:2007-08-01 00:00:00

  • Automated percutaneous lumbar discectomy with and without chymopapain pretreatment versus non-automated discoscopy-monitored percutaneous lumbar discectomy. An experimental study in human cadaver spines.

    abstract::Percutaneous lumbar discectomy has gained growing interest during recent years as an alternative to open surgery for protrusions and non-sequestrated subligamentous intervertebral disc herniations. As a less invasive method it competes with chemonucleolysis. At least two modifications are known to date: automated perc...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/BF00453143

    authors: Pfeiffer M,Schäfer T,Griss P,Mennel HD,Arndt D,Henkel K

    更新日期:1990-01-01 00:00:00

  • Dedifferentiated chondrosarcoma of the thumb: a case report.

    abstract::Dedifferentiated chondrosarcoma (DDCS) comprises approximately 10% of all chondrosarcomas and has the worst outcome with 5-year survival of 10%. The preferred localizations are femur, humerus and pelvis. We report a case of DDCS that arose in proximal phalanx of left-hand thumb of a 66-year-old man. He was admitted wi...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-007-0538-x

    authors: Doganavsargil B,Argin M,Sezak M,Sabah D,Sarsik B,Omur O,Oztop F

    更新日期:2009-02-01 00:00:00

  • Retrograde stem removal in revision hip surgery: removing a loose or broken femoral component with a retrograde nail.

    abstract:INTRODUCTION:Removal of a cemented femoral stem during revision total hip arthroplasty is a technically demanding procedure that requires a multitude of surgical techniques and tools. To gain full access to the cement and the stem, distal fenestration or a transfemoral approach is often required. This paper presents a ...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-010-1063-x

    authors: Tóth K,Sisák K,Nagy J,Manó S,Csernátony Z

    更新日期:2010-07-01 00:00:00

  • Minimally invasive internal fixator for unstable pelvic ring injuries with a pedicle screw-rod system: a retrospective study of 23 patients after 13.5 months.

    abstract:PURPOSE:Pelvic ring fractures are challenging injuries and require effective treatment due to the frequently compromised patient condition. The aim of this study was to evaluate the outcome of unstable pelvic ring injuries treated with a minimally invasive pedicle screw-rod system. METHODS:Retrospective analysis was p...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-018-3094-7

    authors: Hua X,Yan SG,Cui Y,Yin Z,Schreiner AJ,Schmidutz F

    更新日期:2019-04-01 00:00:00

  • Management of intraarticular proximal interphalangeal joint fracture-dislocations and pilon fractures with the Ligamentotaxor® device.

    abstract:INTRODUCTION:Fracture-dislocation and pilon injuries of the proximal interphalangeal joints (PIPJ) continue to pose significant management challenges. Stable fracture configurations can be treated with extension block splinting or pinning. Unstable fractures usually require open or closed reduction and fixation either ...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-020-03482-8

    authors: Mabvuure NT,Pinto-Lopes R,Sierakowski A

    更新日期:2020-08-01 00:00:00

  • Long term results of the Corin C-Fit uncemented total hip arthroplasty in young patients.

    abstract:INTRODUCTION:We conducted a prospective study to evaluate the long-term results after Corin C-Fit uncemented total hip arthroplasty in young patients with hydroxyapatite or porous coated components. MATERIALS AND METHODS:We prospectively followed 36 patients (38 hips) who had Corin C-Fit uncemented total hip arthropla...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-007-0557-7

    authors: Raj D,Jaiswal PK,Sharma BL,Fergusson CM

    更新日期:2008-12-01 00:00:00

  • Cobalt serum levels differ in well functioning Birmingham resurfacing and Birmingham modular THA.

    abstract:INTRODUCTION:Metal-on-metal (MoM) bearings are known to release metal ions secondary to wear and corrosion. This may cause local reactions (adverse soft tissue reactions and osteolysis) and systemic effects. Little is known about the exact pattern and the differences between large head MoM total hip replacements (THA) ...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-016-2439-3

    authors: Renner L,Faschingbauer M,Schmidt-Braekling T,Boettner F

    更新日期:2016-05-01 00:00:00

  • Evaluation of the integrity of the deltoid ligament in supination external rotation ankle fractures: a systematic review of the literature.

    abstract:BACKGROUND AND PURPOSE:Review the literature concerning modalities to evaluate the integrity of the deltoid ligament in patients with supination external rotation ankle fractures. METHODS:The electronic databases Pubmed/Medline, CINAHL and Embase were searched from 1987 to November 2007 to identify all published origi...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章,评审

    doi:10.1007/s00402-008-0768-6

    authors: van den Bekerom MP,Mutsaerts EL,van Dijk CN

    更新日期:2009-02-01 00:00:00

  • Risk of neurological injury in posterior bone block surgery for recurrent glenohumeral instability: a cadaveric study.

    abstract:INTRODUCTION:Recurrent posterior glenohumeral instability poses a challenge for treatment. Bone block procedures have been advocated in cases where a bony defect is present. However, these techniques are not free of complications due to the proximity of neurovascular structures. The aim of this study is to measure the ...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-018-2986-x

    authors: Valencia Mora M,Martínez Menduiña A,Hernández Galera C,Pérez Expósito R,Aramberri Gutiérrez M

    更新日期:2018-12-01 00:00:00

  • Reconstruction of AAOS type III and IV acetabular defects with the Ganz reinforcement ring: high failure in pelvic discontinuity.

    abstract:BACKGROUND:Large acetabular defects and pelvic discontinuity represent complex problems in revision total hip arthroplasty. This study aimed to investigate whether reconstruction with the Ganz reinforcement ring would provide durable function in large acetabular defects. PATIENTS AND METHODS:46 hips (45 patients, 19 m...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-017-2731-x

    authors: Hourscht C,Abdelnasser MK,Ahmad SS,Kraler L,Keel MJ,Siebenrock KA,Klenke FM

    更新日期:2017-08-01 00:00:00

  • Does discoid lateral meniscus have inborn peripheral rim instability? Comparison between intact discoid lateral meniscus and normal lateral meniscus.

    abstract:INTRODUCTION:Little is known about peripheral rim instability (PRI) of adult discoid lateral meniscus (DLM). We compared PRI of the intact DLM (iDLM) to those of intact normal lateral meniscus (LM) in adult patients and also investigated whether there was any association between PRI and DLM tears. MATERIALS AND METHOD...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-018-2987-9

    authors: Kim JH,Bin SI,Lee BS,Kim JM,Kim NK,Lee CR

    更新日期:2018-12-01 00:00:00

  • Chronic painful sesamoids of the thumb.

    abstract::In patients with persistent localized pain at the level of a sesamoid bone of the thumb not obviously related to trauma, sesamoidectomy gives excellent results. Often no X-ray or histological abnormalities are found, leaving the origin of pain problems still unsolved. ...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/BF00431360

    authors: van der Voort JH,Kon M

    更新日期:1990-01-01 00:00:00

  • Suture anchor fixation strength in osteopenic versus non-osteopenic bone for rotator cuff repair.

    abstract:INTRODUCTION:Rotator cuff tears are increasing with age. Does osteopenic bone have an influence on the pullout strength of suture anchors? MATERIALS AND METHODS:SPIRALOK 5.0 mm (DePuy Mitek), Super Revo 5 mm and UltraSorb (both ConMed Linvatec) suture anchors were tested in six osteopenic and six healthy human cadaver...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-008-0689-4

    authors: Pietschmann MF,Fröhlich V,Ficklscherer A,Gülecyüz MF,Wegener B,Jansson V,Müller PE

    更新日期:2009-03-01 00:00:00

  • Tibia fracture following removal of the ETN (Expert Tibia Nail): a case report.

    abstract::We report on a patient who sustained a fracture of the tibial shaft during the removal of the newest type of an intramedullary nail (Expert Tibia Nail, Synthes. In this case report, we discuss the causes of this complication and possible ways to prevent this. ...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-008-0805-5

    authors: Seebauer CJ,van Scherpenzeel KM,Haas NP,Bail HJ

    更新日期:2009-07-01 00:00:00

  • The value of magnetic resonance imaging as postoperative control after arthroscopic treatment of osteochondritis dissecans.

    abstract::The purpose of our study was to evaluate the value of MRI for preoperative arthroscopical planning in patients with osteochondritis dissecans. Based on the experience from 136 patients with osteochondritis dissecans of the knee or the ankle who were arthroscopically operated by retrograde drilling a follow-up study wa...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s004020050235

    authors: Schneider T,Fink B,Jerosch J,Assheuer J,Rüther W

    更新日期:1998-01-01 00:00:00

  • Does repair of deltoid ligament contribute to restoring a mortise in SER type IV ankle fracture with syndesmotic diastasis?

    abstract:PURPOSE:To analyze the radiographic and clinical outcomes of deltoid ligament repair, we studied 34 supination external rotation type IV ankle fracture patients with deltoid ruptures who required syndesmosis fixation. METHODS:We retrospectively evaluated 34 cases of ruptured deltoid ligaments with associated supinatio...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-020-03645-7

    authors: Choi S,Choi Y,Baek E,Jo S

    更新日期:2020-10-29 00:00:00

  • Patient-reported outcome assessment after total joint replacement: comparison of questionnaire completion times on paper and tablet computer.

    abstract:INTRODUCTION:Patient-reported outcome (PRO) assessment is becoming increasingly important after joint replacement surgery. However, PRO data collection, questionnaire handling, and data processing are time consuming and costly process. The aim of our study was to evaluate the efficiency of PRO assessment using tablet c...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-015-2222-x

    authors: Kesterke N,Egeter J,Erhardt JB,Jost B,Giesinger K

    更新日期:2015-07-01 00:00:00

  • Revision total knee arthroplasty due to bone cement and metal hypersensitivity.

    abstract:INTRODUCTION:Hypersensitivity to implants is a rare complication of total knee arthroplasty (TKA). Metal and, less frequently, bone cement can produce allergic symptomatology that if unresponsive to conservative treatment could lead to revision. MATERIALS AND METHODS:We present the case of a patient with generalized p...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-016-2614-6

    authors: Stathopoulos IP,Andrianopoulos N,Paschaloglou D,Tsarouchas I

    更新日期:2017-02-01 00:00:00

  • Variations in the origin of the medial and inferior calcaneal nerves.

    abstract:INTRODUCTION:Entrapment of the medial heel region nerves is often mentioned as a possible cause of heel pain. Some authors have suggested that the medial and inferior calcaneal nerves may be involved in such heel pain, including plantar fasciitis, heel pain syndrome and fat pad disorders. The aim of this study was to g...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-005-0088-z

    authors: Govsa F,Bilge O,Ozer MA

    更新日期:2006-01-01 00:00:00

  • Compound osteosynthesis of pathological fractures of the proximal femoral shaft. Experimental studies on the biomechanical effects of additional intramedullary splinting.

    abstract::The biomechanical stability of two compound osteosynthesis techniques with and without intramedullary splinting were compared in 20 paired cadaver femora. Group A was stabilised using a contoured 12-hole DC plate and polymethylmethacrylate cement. In group B an additional intramedullary semi-diameter osteosynthesis pl...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/BF00573454

    authors: Heller KD,Zilkens KW,Cohen B,Hammer J

    更新日期:1996-01-01 00:00:00

  • Stability of capsule closure and postoperative anterior knee pain after medial parapatellar approach in TKA.

    abstract:PURPOSE:Anterior knee pain after total knee arthroplasty (TKA) remains a widely discussed postoperative complication. In contrast to sports traumatology, the role of the dissected medial patellofemoral ligament (MPFL) using a medial parapatellar approach in TKA has not been discussed so far. In the present study, it wa...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-017-2706-y

    authors: Keshmiri A,Dotzauer F,Baier C,Maderbacher G,Grifka J,Sendtner E

    更新日期:2017-07-01 00:00:00

  • Anterior reconstructive spinal surgery with Zielke instrumentation for metastatic malignancies of the spine.

    abstract::From March 1984 to April 1996, 60 consecutive patients with spinal metastasis underwent palliative surgery by anterior corpectomy and Zielke instrumentation. Their ages ranged from 21 to 76 years (mean 54 years). Thirty-two patients had metastasis to the thoracic spine, 20 to the lumbar spine, and 8 had both thoracic ...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/pl00021238

    authors: Chen LH,Chen WJ,Niu CC,Shih CH

    更新日期:2000-01-01 00:00:00

  • A lateral retinacular release during total knee arthroplasty changes femorotibial kinematics: an in vitro study.

    abstract:INTRODUCTION:Lateral retinacular release (LRR) is a common procedure during total knee arthroplasty (TKA), especially if patellar maltracking is observed intraoperatively. The impact of LRR on patellofemoral kinematics is well-examined, but the influence on femorotibial kinematics requires more elucidation. Therefore, ...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-017-2843-3

    authors: Steinbrück A,Schröder C,Woiczinski M,Glogaza A,Müller PE,Jansson V,Fottner A

    更新日期:2018-03-01 00:00:00

  • Gaucher disease--the orthopaedic aspect. Report of seven cases.

    abstract::Seven patients with Gaucher type 1 disease are presented: five female and two male. The orthopaedic problems encountered were: avascular necrosis of both femoral heads in two girls, bilateral bone infarctions of the femurs in all three girls, complicated by staphylococcal osteomyelitis of the right femur in one girl a...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/BF00443393

    authors: Tauber C,Tauber T

    更新日期:1995-01-01 00:00:00

  • A rare case of progressive bilateral congenital abduction contracture with shoulder dislocations treated with proximal deltoid release.

    abstract::The contracture of the deltoid muscle is an uncommon disorder. Amongst the various causes reported, post intramuscular injection and trauma leading to the fibrosis of the muscle are common. However, congenital cases are extremely rare. We report a case of congenital progressive bilateral abduction contracture left unt...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-007-0291-1

    authors: Bhagat S,Bansal M,Sharma H,Jandhyala R,Amin P,Pandit J

    更新日期:2008-03-01 00:00:00

  • Simple and comminuted displaced olecranon fractures: a clinical comparison between tension band wiring and plate fixation techniques.

    abstract:INTRODUCTION:The purpose of this retrospective study is to compare the clinical, functional outcome and complications occurrence between tension band wiring (TBW) and plate fixation both for simple and comminuted displaced olecranon fractures. MATERIALS AND METHODS:Between January 2005 and June 2012 (minimum 1-year fo...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-014-2021-9

    authors: Tarallo L,Mugnai R,Adani R,Capra F,Zambianchi F,Catani F

    更新日期:2014-08-01 00:00:00

  • The distance of the gluteal nerve in relation to anatomical landmarks: an anatomic study.

    abstract:INTRODUCTION:Gluteal insufficiency is of concern with lateral approaches to total hip arthroplasty. Damage to the branches of the superior gluteal nerve may cause degeneration of the innervated muscles. The direct anterior approach exploits the intermuscular and internerval interval between tensor fasciae latae lateral...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-017-2847-z

    authors: Putzer D,Haselbacher M,Hörmann R,Thaler M,Nogler M

    更新日期:2018-03-01 00:00:00

  • Bone density correlates with clinical outcomes after ankle fracture fixation.

    abstract:INTRODUCTION:Osteoporosis and decreased bone density are known to increase fracture incidence and severity. Although much is known regarding the effects of bone density on fracture risk and the treatment options for prevention of fragility fractures, whether bone quality alters clinical outcomes after fracture fixation...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s00402-018-3017-7

    authors: Warner SJ,Garner MR,Fabricant PD,Lorich DG

    更新日期:2018-12-01 00:00:00

  • Biochemical alterations secondary to disuse atrophy in the rat's serum and limb tissues.

    abstract::Disuse atrophy has been the subject of research studies of an animal model in which single-limb immobilization induces atrophic changes in the immobilized limb. These reveal systemic changes in the experimental animals that go far beyond the local response expected in that situation and are not fully understood as yet...

    journal_title:Archives of orthopaedic and trauma surgery

    pub_type: 杂志文章

    doi:10.1007/s004020050011

    authors: Cohen I,Bogin E,Chechick A,Rzetelny V

    更新日期:1999-01-01 00:00:00