Local coagulofibrinolysis in the postsurgical recovery of patients with chronic subdural haematoma.

Abstract:

:Postoperative recovery of patients with chronic subdural haematoma (CSH) was investigated by comparing pre- and postoperative coagulant and fibrinolytic activity in the haematoma contents of 15 patients with SCH. Patients in this study were treated draining the haematoma cavity without irrigation, a procedure dubbed the closed drainage. Haematomas were collected during, and 24 hrs after, surgery. Postoperative fibrinolytic activity was lower than that observed pre-operatively. In particular, levels of tissue plasminogen activator activity (TPA), and fibrin and fibrinogen degradation products (FDP) all decreased. In contrast, coagulant activity increased postoperatively. This paper will discuss the role of local coagulofibrinolysis in the postoperative recovery of CSH patients.

journal_name

Acta Neurochir (Wien)

journal_title

Acta neurochirurgica

authors

Matsumoto M,Sakata Y,Yamazaki T,Endo G,Ohishi H,Takasu N

doi

10.1007/s007010050283

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

177-81

issue

2

eissn

0001-6268

issn

0942-0940

journal_volume

141

pub_type

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